[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ege University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":687},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,33,0,25,[9,46,80,105,131,160,185,212,241,269,296,320,346,371,395,423,452,477,502,527,547,583,610,639,661],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100637857","video-assisted-emotional-preparation-and-emotional-expression-during-subcutaneous-procedures-in-children-with-cancer-100637857",false,"NCT07602621","Video-Assisted Emotional Preparation and Emotional Expression During Subcutaneous Procedures in Children With Cancer","The Effect of Video-Assisted Emotional Preparation on Emotional Expression in Children With Cancer Undergoing Subcutaneous Procedures","Inclusion Criteria:\n\n* The child must be between the ages of 3 and 6,\n* The child must be receiving inpatient treatment at the Pediatric Hematology Clinic,\n* The child must be scheduled to undergo a subcutaneous procedure related to a leukemia diagnosis\n* The child and parent must agree to participate in the study and provide written informed consent,\n* The child and parent must be able to communicate in basic Turkish,\n* At least one parent (mother or father) must be present with the child during the procedure.\n\nExclusion Criteria:\n\n* Development of an acute or unstable clinical condition\n* The child's discharge or continuation of treatment on an outpatient basis\n* A single SC procedure performed based on the child's clinical condition\n* The child has received sedation or a medication causing confusion prior to the procedure\n* The child has severe vision or hearing problems that prevent video viewing or a structured emotional preparation interview\n* Another interventional procedure is scheduled for the same day\n* Withdrawal of informed consent by the child or parent during the process\n* Difficulty adhering to the study protocol (e.g., discontinuing the procedure or refusing the procedure).\n* If communication or cooperation issues prevent the completion of research data, the case will be excluded from the study.","ALL","3 Years","6 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this randomized controlled trial is to evaluate whether video-assisted emotional preparation helps reduce emotional distress in children with leukemia undergoing subcutaneous procedures. The study will also examine whether this intervention affects procedure duration and crying time during the procedure.\n\nThe main questions it aims to answer are:\n\n* Does video-assisted emotional preparation improve children's emotional expression during subcutaneous procedures?\n* Does the intervention reduce the duration of the procedure?\n* Does the intervention shorten crying time during the procedure?\n\nResearchers will compare video-assisted structured emotional preparation with structured emotional preparation alone and routine care to determine the effectiveness of the intervention.\n\nParticipants will be randomly assigned to one of three groups:\n\n* video-assisted structured emotional preparation,\n* structured emotional preparation only,\n* or routine care",[28],"Pediatric Leukemia",[30,31,32,33],"emotional expression","subcutaneous tretament","pediatric nursing","video assisted intervention","NOT_YET_RECRUITING","2026-05-21",{"date":37,"type":38},"2026-05-26","ACTUAL",{"date":40,"type":22},"2026-07-01",{"date":42,"type":22},"2027-07-01",{"name":44,"class":45},"Ege University","OTHER",{"id":47,"slug":48,"hasResults":12,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":12,"sex":17,"minAge":19,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":56,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},"100589509","music-and-vr-effects-on-pain-anxiety-and-fear-during-oral-mucositis-care-in-leukaemic-children-100589509","NCT06955338","Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children","The Effect of Music Recital and Virtual Reality on Pain, Anxiety and Fear During Oral Mucositis Care in Children With Leukaemia: A Randomised Controlled Study","Inclusion Criteria:\n\nThe participant child\n\n* is between the ages of 6-12 years\n* is being followed up as an inpatient in the Paediatric Haematology Clinic\n* is receiving leukaemia treatment only\n* has oral mucositis\n* does not have a systemic infection\n* willing to participate in the study\n* speak Turkish and are open to communication\n* has no visual and hearing problems (not using glasses or hearing aids)\n\nExclusion Criteria:\n\n* Cases not fulfilling the inclusion criteria will be excluded from the study.","12 Years",{"count":55,"type":22},45,[25],"Children undergoing leukaemia treatment are exposed to a wide range of chemotherapeutic agents and immunosuppressive therapies during treatment and are therefore at great risk for complications. Mucositis is one of the leading chemotherapy-related complications affecting the quality of life of the child. Although it varies according to the degree of mucositis, oral mucosal erythema, white plaques and ulcers are extremely painful and traumatising procedures for pediatric patients during mucositis care. The pain and fear they experience during the procedure may lead children to delay\u002Fnot perform oral mucositis care or not allow their parents to do so. Since mucositis is a painful condition in children, it is recommended to use distracting nonpharmacological methods that can help reduce the pain and fear of children during mucositis care. In this context, the aim of this study was to determine the effects of music and virtual reality on pain, anxiety and fear during oral mucositis care in children aged 6-12 years receiving leukaemia treatment. Block randomisation (gender (F\u002FM) and age groups (6-9\u002F10-12) will be used to identify participants. Five minutes before the oral mucositis care procedure, all participants, regardless of group, will be assessed with the Child Anxiety Scale-Disposition (CAS-D), Child Fear Scale and Visual Analogue Scale (VAS). The study will be conducted in three groups as control group, VR group and music group. Descriptive characteristics of dependent and independent categorical variables will be given as number and percentage, numerical descriptive characteristics will be given as mean and standard deviation. In examining the relationship between dependent and independent variables, Mann Whitney-Kruskal Wallis or Student t-Anova analyses will be performed according to the result of the analysis of conformity to normal distribution. Bonferroni analysis will be used for pairwise comparisons and Covariance analysis will be used to investigate the effect of variables with children.",[59,60,61],"Anxiety","Pain","Fear",[63,64,65,66,67,68,69,70],"leukemia","mucositis","fear","anxiety","pain","children","nursing","symptom management","2026-05-16",{"date":73,"type":38},"2026-05-19",{"date":75,"type":22},"2026-12-01",{"date":77,"type":22},"2027-12-01",{"name":44,"class":45},1,{"id":81,"slug":82,"hasResults":12,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":23,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100640400","the-effect-of-video-assisted-mindfulness-based-breathing-on-quality-of-life-and-mental-well-being-in-individuals-with-breast-cancer-100640400","NCT07575386","The Effect of Video-Assisted Mindfulness-Based Breathing on Quality of Life and Mental Well-Being in Individuals With Breast Cancer","Inclusion Criteria:\n\nDiagnosed with breast cancer Aged 18 years or older Stage I, II, or III breast cancer Completed at least 4 cycles of chemotherapy Completed chemotherapy treatment Able to understand and speak Turkish Has access to a digital device (smartphone, tablet, or computer) Willing to participate in the study\n\n✔ Exclusion Criteria: Diagnosis of another type of cancer Presence of psychiatric disorders (e.g., schizophrenia, bipolar disorder, major depression, anxiety disorders) Stage IV breast cancer Presence of respiratory problems Previous or current experience with yoga or meditation Refusal to participate in the study","18 Years",{"count":88,"type":22},50,[25],"This study aims to evaluate the effect of video-assisted mindfulness-based breathing on quality of life and mental well-being in individuals with breast cancer. Breast cancer patients often experience physical and psychological challenges that negatively affect their quality of life. Mindfulness-based breathing is a simple, non-invasive method that may help reduce stress and improve well-being.\n\nIn this randomized controlled study, participants will be assigned to either an intervention group or a control group. The intervention group will receive a face-to-face breathing training session and will practice daily mindfulness-based breathing exercises using a 5-minute video for 6 weeks. The control group will receive routine care.\n\nOutcomes will be measured at baseline and after 6 weeks using validated scales assessing quality of life and mental well-being. This study aims to provide evidence for a simple and accessible supportive care method for individuals with breast cancer.",[92],"Breast Cancer",[92,94,95,96],"Mindfulness","Quality of Life","Mental Well-being","2026-05-02",{"date":99,"type":38},"2026-05-08",{"date":101,"type":22},"2026-09-02",{"date":103,"type":22},"2027-06-02",{"name":44,"class":45},{"id":106,"slug":107,"hasResults":12,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":23,"phases":115,"briefSummary":116,"conditions":117,"keywords":119,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":4},"100635732","telerehabilitation-dual-task-training-in-temporomandibular-joint-dysfunction-100635732","NCT07556510","Telerehabilitation Dual-Task Training in Temporomandibular Joint Dysfunction","Effect of Telerehabilitation-Based Dual-Task Training on Clinical Outcomes in Temporomandibular Joint Dysfunction","Inclusion Criteria:\n\n* Diagnosis of temporomandibular joint dysfunction according to the\n* Temporomandibular Disorders Research Diagnostic Criteria and Diagnostic\n* Criteria for Temporomandibular Disorders\n* No neurological, orthopedic, or systemic condition that may affect balance\n* Ability to comply with a telerehabilitation program\n* Willingness to provide written informed consent\n* No prior physiotherapy treatment for temporomandibular joint dysfunction\n\nExclusion Criteria:\n\n* Inability to participate in regular exercise or telerehabilitation programs\n* Presence of severe systemic diseases (cardiac, rheumatologic, neurological) or other severe chronic conditions\n* Presence of psychiatric disorders or cognitive impairment\n* Use of medications that may affect balance (such as sedatives)\n* History of jaw or dental surgery within the last 6 months\n* Receipt of physiotherapy, splint therapy, or similar treatment for temporomandibular joint dysfunction within the last 3-6 months","25 Years",{"count":114,"type":22},30,[25],"This randomized controlled trial will be conducted among 18-25-year-old participants who present with temporomandibular joint dysfunction symptoms, including pain, limited range of motion, and joint crepitation. Participants will be randomly allocated into control and intervention groups using block randomization. The control group will receive a standard physiotherapy program, while the intervention group will additionally perform telerehabilitation-based dual-task exercises. The intervention will last for six weeks, with progressive increases in exercise and cognitive task difficulty. Outcomes will be assessed at baseline and at the end of the 6th week. Primary and secondary outcome measures include pain intensity (Visual Analog Scale), jaw functional limitation (Jaw Functional Limitation Scale-20), oral habits, static balance (Tetrax system), and dynamic balance (Timed Up and Go Test). Within-group and between-group comparisons will be performed. The sample size was calculated using power analysis, resulting in 30 participants in total (15 per group), accounting for potential dropouts.",[118],"Temporomandibular Joint Dysfunction",[120,121,67,122],"temporomandibular joint dysfunction","dual-task","balance","2026-04-29",{"date":125,"type":38},"2026-05-05",{"date":127,"type":22},"2026-06-16",{"date":129,"type":22},"2027-02-16",{"name":44,"class":45},{"id":132,"slug":133,"hasResults":12,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":12,"sex":139,"minAge":86,"maxAge":4,"enrollmentInfo":140,"targetDuration":4,"studyType":141,"phases":4,"briefSummary":142,"conditions":143,"keywords":148,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":79},"100630709","effect-of-trendelenburg-position-and-pneumoperitoneum-on-optic-nerve-sheath-diameter-in-robot-assisted-prostatectomy-100630709","NCT07491198","Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted Prostatectomy","Effect of Steep Trendelenburg Position and Pneumoperitoneum on Optic Nerve Sheath Diameter in Robot-Assisted Laparoscopic Radical Prostatectomy: A Prospective Study","ONSD-RALP","Inclusion Criteria:\n\n* Age ≥ 18 years\n* ASA physical status I-III\n* Patients scheduled for robot-assisted laparoscopic radical prostatectomy or open radical prostatectomy under general anesthesia\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* History of intracranial surgery or intracranial lesion\n* Known ocular disease (glaucoma, retinal detachment, diabetic retinopathy, previous ocular surgery, etc.)\n* Intraocular pressure greater than 30 mmHg\n* Refusal to participate in the study","MALE",{"count":88,"type":22},"OBSERVATIONAL","This prospective study aims to evaluate the effect of steep Trendelenburg position and pneumoperitoneum on optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic radical prostatectomy and open radical prostatectomy under general anesthesia. Increased intracranial pressure may occur during robotic surgery due to pneumoperitoneum and head-down positioning. Optic nerve sheath diameter measured by ocular ultrasonography is a non-invasive method used to assess intracranial pressure changes. Hemodynamic and respiratory parameters will also be recorded during surgery. The results of this study may help to better understand the physiological effects of surgical position and pneumoperitoneum during prostatectomy procedures.",[144,145,146,147],"Prostate Cancer","Optic Nerve Sheath Diameter","Robot-Assisted Radical Prostatectomy","Steep Trendelenburg Position With Penumoperitoneum in Robot Assisted Laparoscopic Prostatectomy",[145,149,150,146],"Trendelenburg Position","Pneumoperitoneum","RECRUITING","2026-03-18",{"date":154,"type":38},"2026-03-24",{"date":156,"type":38},"2026-01-05",{"date":158,"type":22},"2026-09",{"name":44,"class":45},{"id":161,"slug":162,"hasResults":12,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":168,"targetDuration":4,"studyType":141,"phases":4,"briefSummary":170,"conditions":171,"keywords":176,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":179,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":79},"100630708","effect-of-glycemic-control-on-intraoperative-nirs-and-postoperative-recovery-in-diabetic-patients-100630708","NCT07491185","Effect of Glycemic Control on Intraoperative NIRS and Postoperative Recovery in Diabetic Patients","Effects of Intraoperative Near-Infrared Spectroscopy and Postoperative Recovery on Glycemic Control Levels in Patients With Diabetes Mellitus: A Prospective Study","NIRS-DM","Inclusion Criteria:\n\n* Age ≥18 years\n* Patients scheduled for elective urologic surgery under general anesthesia\n* ASA physical status I-III\n* Patients with diabetes mellitus or non-diabetic control patients\n* Availability of preoperative HbA1c measurement\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* ASA physical status \\>III\n* Emergency surgery\n* History of cerebrovascular disease or neurological disorder\n* Previous brain or neurological surgery\n* Inability to communicate or refusal to participate\n* Intraoperative hemodynamic instability\n* Inadequate NIRS monitoring data",{"count":169,"type":22},80,"This prospective observational study aims to evaluate the effect of glycemic control level on intraoperative cerebral oxygenation measured by near-infrared spectroscopy (NIRS) and postoperative recovery in patients with diabetes mellitus undergoing elective urologic surgery under general anesthesia.\n\nPatients will be grouped according to HbA1c levels to assess the relationship between long-term glycemic control and intraoperative regional cerebral oxygen saturation, hemodynamic parameters, and postoperative recovery scores.",[172,173,174,175],"Diabetes Mellitus","Glycemic Control","Cerebral Oxygenation","Anesthesia",[172,173,177,178],"Near-Infrared Spectroscopy","Postoperative Recovery",{"date":154,"type":38},{"date":181,"type":38},"2025-11-01",{"date":183,"type":22},"2027-03",{"name":44,"class":45},{"id":186,"slug":187,"hasResults":12,"nctId":188,"briefTitle":189,"officialTitle":190,"acronym":4,"eligibilityCriteria":191,"healthyVolunteers":12,"sex":17,"minAge":192,"maxAge":53,"enrollmentInfo":193,"targetDuration":4,"studyType":23,"phases":195,"briefSummary":196,"conditions":197,"keywords":198,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":79},"100628944","effect-of-helfer-skin-tap-and-vibration-on-pain-and-fear-in-children-during-intramuscular-injection-100628944","NCT07468227","Effect of Helfer Skin Tap and Vibration on Pain and Fear in Children During Intramuscular Injection","The Effect of Helfer Skin Tap and Vibration Techniques on Pain and Fear During Intramuscular Injection in Children Aged 5-12 Years in the Pediatric Emergency Department: A Randomized Controlled Trial","Inclusion Criteria:\n\n* The child must be in the 5-10 age group\n* Intramuscular injection must be performed,\n* The child must be able to communicate in Turkish,\n* Verbal\u002Fwritten consent must be obtained from the parents\u002Flegal guardians\n\nExclusion Criteria:\n\n* Known neurological disorders,\n* Inability to communicate cognitively,\n* Chronic pain syndrome\n* Acute and life-threatening clinical condition","5 Years",{"count":194,"type":22},186,[25],"Intramuscular injection is one of the most common invasive procedures in childhood and is frequently associated with pain and fear. These negative experiences may affect children's attitudes toward healthcare and complicate nursing care. Therefore, using non-pharmacological methods is essential for promoting child-friendly services. This study aims to evaluate the effects of the Helfer Skin Tap and vibration techniques on pain and fear levels in children aged 5-10 years during intramuscular injections.\n\nThe study is designed as a parallel, three-arm randomized controlled trial conducted in the Pediatric Emergency Clinic of Ege University Hospital. Participants will be allocated by simple randomization to Helfer Skin Tap, vibration, or standard care. Sample size was calculated with G\\*Power 3.1 using a repeated-measures within-between interaction model with two time points (T0-T1), α=0.05, and power=0.80. Assuming a medium effect size (f=0.25) based on previous studies, at least 159 children are required. Allowing for 15% attrition, the final sample will include 186 participants (62 per group).\n\nData will be collected using a Child Information Form including sociodemographic characteristics and prior injection experiences. A Procedure Record Form will document randomization, assigned group, medication, dose, injection site, duration, child's position, and parental presence.\n\nPain and fear will be assessed immediately before (T0) and after (T1) the injection. Pain will be measured with the Wong-Baker FACES Pain Rating Scale (0-10) and fear with the Children's Fear Scale (0-4). Ratings will be obtained independently from the child, parent, and observing nurse.\n\nThe procedure will be video-recorded to enable objective evaluation of behavioral responses. Recordings will be scored by an independent blinded expert using standardized criteria. Videos will be used only for research purposes, with identifying features concealed, stored in coded format, and destroyed after study completion.",[60,61],[199,200,201,202,203],"pediatric emergency","intramuscular injection","Helfer Skin Tap","vibration","randomized controlled trial","2026-03-11",{"date":206,"type":38},"2026-03-12",{"date":208,"type":22},"2026-05-01",{"date":210,"type":22},"2027-05-01",{"name":44,"class":45},{"id":213,"slug":214,"hasResults":12,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":4,"eligibilityCriteria":218,"healthyVolunteers":12,"sex":17,"minAge":219,"maxAge":4,"enrollmentInfo":220,"targetDuration":4,"studyType":23,"phases":222,"briefSummary":223,"conditions":224,"keywords":229,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":240,"locationsCount":4},"100629313","virtual-reality-based-health-at-my-feet-program-for-individuals-with-type-2-diabetes-100629313","NCT07473050","Virtual Reality-Based 'Health at My Feet' Program for Individuals With Type 2 Diabetes","Virtual Reality-Based 'Health at My Feet' Program for Individuals With Type 2 Diabetes: A Randomized Controlled Study","Inclusion Criteria:\n\n* Being over 18 years of age\n* Having been diagnosed with type 2 diabetes for at least one year\n* Having a risk level of 0, 1, or 2 according to the International Working Group on the Diabetic Foot (IWGDF) Risk Level Classification\n* Having completed primary education or higher\n* Not having hearing, speech, or visual impairments\n* Being able to use a smartphone\n* Not having received prior training in diabetic foot care\n* Being willing to participate in the study\n\nExclusion Criteria:\n\n* Having previously had a diabetic foot ulcer or currently having a diabetic foot ulcer\n\n  \\- Risk level 3 according to the International Working Group on the Diabetic Foot (IWGDF) Risk Level Classification\n* Having a severe\u002Funcontrolled comorbid disease\n* Wishing to withdraw from the study","19 Years",{"count":221,"type":22},70,[25],"This randomized controlled experimental study aims to develop and evaluate the effectiveness of a Virtual Reality-Based \"Health to My Foot\" program designed for individuals with Type II Diabetes Mellitus. The study will assess the program's impact on diabetic foot knowledge, foot care self-efficacy, foot care behaviors, and foot health outcomes.\n\nThe research will be conducted between April and October 2026 at a university hospital diabetes outpatient clinic in İzmir, Türkiye. A total of 70 participants diagnosed with Type II DM will be enrolled and randomly assigned to either the intervention group (n=35) or the control group (n=35) using stratified block randomization.\n\nParticipants in the intervention group will receive the Virtual Reality-Based \"Health to My Foot\" program through virtual reality goggles and will have access to a recorded foot care training video for home use. They will also receive weekly motivational reminder messages for three months. The control group will receive standard outpatient care only.\n\nData will be collected at baseline (pre-test), 1 month (post-test), and 3 months (follow-up) using validated scales and a nurse follow-up form to evaluate knowledge, self-efficacy, behaviors, and clinical foot health indicators. The findings are expected to contribute to sustainable patient education strategies and to support the prevention of diabetic foot complications and reduction of healthcare costs.",[225,226,227,228],"Diabetic Foot - Telemedical Monitoring","Diabetic","Foot Care","Virtual Reality",[230,231,228,69,232],"Diabetic foot","Foot care","nursing care","2026-03-10",{"date":235,"type":38},"2026-03-16",{"date":237,"type":22},"2026-04-16",{"date":239,"type":22},"2026-07-30",{"name":44,"class":45},{"id":242,"slug":243,"hasResults":12,"nctId":244,"briefTitle":245,"officialTitle":246,"acronym":4,"eligibilityCriteria":247,"healthyVolunteers":248,"sex":249,"minAge":86,"maxAge":250,"enrollmentInfo":251,"targetDuration":4,"studyType":23,"phases":252,"briefSummary":253,"conditions":254,"keywords":257,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":79},"100611664","the-effect-of-birth-positions-on-labor-100611664","NCT07243522","The Effect of Birth Positions on Labor","The Effect of Birth Positions on Pelvic Floor Muscle Strength, Severity, and Quality of Perineal Pain in Primiparous Pregnant Women: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Being between 18 and 35 years of age\n* Being primiparous\n* Being at term (37-42 weeks)\n* Being in the latent phase of the first stage of labor\n* Being in the vertex position, having a single, live fetus\n* Having an estimated fetal weight between 2500 and 4000 grams\n* Having a maternal Body Mass Index \\\u003C30\n* Pregnant women who are expected to give birth vaginally\n* Ability to understand and speak Turkish\n* Volunteer to participate in the study\n\nExclusion Criteria:\n\n* Non-cephalic presentation\n* Chronic diseases (heart disease, epilepsy, hypertension, hypothyroidism, diabetes, and kidney disease, etc.)\n* Risk of obstetric complications (gestational hypertension, cephalopelvic disproportion, antepartum hemorrhage, intrauterine growth restriction, premature rupture of membranes, etc.)\n* History of pelvic surgery\n* History of prolapse surgery\n* History of collagen disorder\n* Severe anemia\n* Presence of genital tract infection\n* Abnormalities of the vulva (presence of vulvar edema, scarring, etc.)\n* Application of fundal pressure\n* Interventional delivery (use of forceps\u002Fvacuum during the second stage, etc.)\n* Cesarean section\n* Fetal (risk\u002Fpresence of congenital malformations, estimated fetal weight \\\u003C2500 g or \\>4000 g)",true,"FEMALE","35 Years",{"count":221,"type":22},[25],"This study is a randomized controlled trial aimed at evaluating the effects of positions used during labor on pelvic floor muscle strength and the severity and nature of perineal pain in primiparous pregnant women. The World Health Organization (WHO) recommends supporting women's freedom of movement during the second stage of labor and encouraging upright birthing positions. However, in many countries, births are still performed in supine or lithotomy positions, and knowledge and practice regarding upright positions persist. This situation points to a significant knowledge and practice gap for both birthing women and healthcare professionals.\n\nThe study will be conducted at the Birth Unit of Bakırçay University Çiğli Training and Research Hospital, Izmir. Following ethics committee approval, the study will be conducted within one year. The sample will consist of 70 primiparous pregnant women who present to the birth unit and meet the inclusion criteria. Participants will be randomly assigned to the intervention and control groups via random.org. Pregnant women in the intervention group will deliver in the Semi-Fowler's (semi-sitting) position, while those in the control group will deliver in the lithotomy position, which is the hospital's standard practice.\n\nData will be collected in two stages. In the first stage, data will be collected at the onset of labor and when cervical dilation reaches 8-10 cm. In the second stage, data will be collected within 24 hours after delivery, at 6 weeks and 6 months postpartum. Data collection tools will be administered to each woman a total of five times in the first and second stages. Pelvic floor muscle strength will be assessed both objectively with a perineometer and subjectively with the Oxford scale. The severity and nature of perineal pain will be measured with the McGill Pain Scale Short Form.\n\nThe hypotheses of the study are that delivering in a semi-sitting position will increase pelvic floor muscle strength and reduce perineal pain. The data will be analyzed using the SPSS 23 software package, using parametric and non-parametric tests. Intention-to-treat (ITT) analysis will be applied when necessary to mitigate the impact of data loss.\n\nThis study aims to evaluate not only the effects of birthing positions on the labor process but also their impact on women's health in the postpartum period. This research, which will contribute to expanding the limited literature on this topic, is also expected to support the widespread adoption of a woman-centered approach to care in maternity services.",[255,256],"Primipara Pregnant","Primipara Labour",[258,259,260],"birth positions","pelvic floor","perineal pain","2026-03-01",{"date":263,"type":38},"2026-03-03",{"date":265,"type":38},"2025-10-07",{"date":267,"type":22},"2026-10-07",{"name":44,"class":45},{"id":270,"slug":271,"hasResults":12,"nctId":272,"briefTitle":273,"officialTitle":274,"acronym":4,"eligibilityCriteria":275,"healthyVolunteers":12,"sex":17,"minAge":276,"maxAge":4,"enrollmentInfo":277,"targetDuration":4,"studyType":141,"phases":4,"briefSummary":279,"conditions":280,"keywords":284,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":79},"100626978","frailty-and-outcomes-in-older-emergency-department-patients-with-pneumonia-100626978","NCT07442656","Frailty and Outcomes in Older Emergency Department Patients With Pneumonia","Impact of Clinical Frailty Scale on Morbidity and Mortality in Older Adults Diagnosed With Pneumonia in the Emergency Department: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Age ≥65 years\n* Clinical and radiological diagnosis of pneumonia in the emergency department\n* Ability to obtain informed consent from the patient or legal representative\n* Availability of a caregiver or relative able to describe baseline functional status\n\nExclusion Criteria:\n\n* Presentation with cardiopulmonary arrest or ongoing cardiopulmonary resuscitation at admission\n* Confirmed COVID-19 pneumonia\n* Inability to obtain reliable baseline functional history due to absence of an informant\n* Refusal to provide informed consent","65 Years",{"count":278,"type":22},150,"Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on acute physiological derangements and may not adequately capture biological reserve and frailty in older adults. Frailty is a geriatric syndrome reflecting increased vulnerability to stressors and reduced recovery capacity.\n\nThis prospective observational cohort study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS) for in-hospital mortality, 30-day mortality, and morbidity in patients aged 65 years and older presenting to the emergency department with pneumonia. Additionally, the study will assess whether incorporating frailty assessment into existing pneumonia severity scores improves prognostic accuracy.",[281,282,283],"Community-Acquired Pneumonia","Fraility","Hospitalizations",[282,285,286,287],"Clinical Fraility Scale","Older adults","Geriatric Emergency Medicine","2026-02-26",{"date":290,"type":38},"2026-03-02",{"date":292,"type":38},"2026-01-01",{"date":294,"type":22},"2026-04-30",{"name":44,"class":45},{"id":297,"slug":298,"hasResults":12,"nctId":299,"briefTitle":300,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":12,"sex":17,"minAge":302,"maxAge":53,"enrollmentInfo":303,"targetDuration":4,"studyType":23,"phases":304,"briefSummary":305,"conditions":306,"keywords":310,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":313,"lastUpdatePostDateStruct":314,"startDateStruct":316,"completionDateStruct":318,"leadSponsor":319,"locationsCount":79},"100608606","the-effect-of-mandala-on-anxiety-and-fear-levels-in-children-with-leukemia-before-intrathecal-chemotherapy-treatment-100608606","NCT07203742","The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment","Inclusion Criteria:\n\n* The patient must be between 4 and 12 years of age.\n* The patient must be hospitalized and followed up at the Pediatric Hematology Clinic.\n* The patient must only be receiving leukemia treatment.\n* The patient must not have any other chronic diseases.\n* The patient must not have any systemic infections.\n* The patient has received at least two courses of intrathecal chemotherapy treatment\n* The patient does not have a diagnosis of psychological\u002Fmental symptoms as a side effect of chemotherapy treatment\n* Intrathecal treatment will be administered to the patient in accordance with the chemotherapy protocol\n* The patient and the caregiver parent are volunteers\n* The caregiver parent speaks Turkish and is open to communication.\n\nExclusion Criteria:\n\n* Cases that do not meet the inclusion criteria will be excluded from the study.","4 Years",{"count":21,"type":22},[25],"This study aims to examine the effect of mandala coloring activity, administered before intrathecal chemotherapy treatment in children with leukemia, on pre-procedure anxiety and fear in children. The main question this study aims to answer is:\n\nDoes mandala coloring administered before intrathecal chemotherapy treatment reduce pre-procedure anxiety and fear in children with leukemia?\n\nDescriptive demographic data will be collected from the children who will be given mandalas. Data will be collected using an Anxiety Scale and a Fear Scale.",[307,308,309],"Acute Lymphoblastic Leukemia","Childhood Acute Leukemia","Acute Myeloblastic Leukaemia",[311,66,65,312,69],"intrathechal chemotherapy treatment","mandala","2026-02-13",{"date":315,"type":38},"2026-02-17",{"date":317,"type":38},"2025-09-29",{"date":158,"type":22},{"name":44,"class":45},{"id":321,"slug":322,"hasResults":12,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":4,"eligibilityCriteria":326,"healthyVolunteers":12,"sex":249,"minAge":86,"maxAge":327,"enrollmentInfo":328,"targetDuration":4,"studyType":23,"phases":330,"briefSummary":331,"conditions":332,"keywords":334,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":338,"lastUpdatePostDateStruct":339,"startDateStruct":341,"completionDateStruct":343,"leadSponsor":345,"locationsCount":79},"100622990","prophylactic-tranexamic-acid-in-low-risk-repeat-cesarean-delivery-a-randomized-controlled-trial-100622990","NCT07390799","Prophylactic Tranexamic Acid in Low-Risk Repeat Cesarean Delivery: A Randomized Controlled Trial","Effect of Prophylactic Tranexamic Acid Administered After Fetal Delivery on Perioperative Blood Loss and Neonatal Outcomes in Low-Risk Repeat Cesarean Delivery: A Randomized Controlled Trial","Inclusion Criteria:\n\nWomen aged 18 to 45 years Singleton pregnancy Gestational age ≥37+0 weeks Scheduled second or third cesarean delivery Classified as low risk for postpartum hemorrhage Ability to provide written informed consent Planned cesarean delivery under regional or general anesthesia\n\nExclusion Criteria:\n\nPrimary cesarean delivery More than three previous cesarean deliveries Placenta previa, placenta accreta spectrum, or suspected abnormal placentation Multiple pregnancy Known coagulation disorders or use of anticoagulant therapy History of thromboembolic disease Severe anemia (hemoglobin \\\u003C10 g\u002FdL) Hypertensive disorders of pregnancy (including preeclampsia or eclampsia) Intrauterine fetal demise Emergency cesarean delivery Known hypersensitivity to tranexamic acid","45 Years",{"count":329,"type":22},204,[25],"Postpartum hemorrhage remains a leading cause of maternal morbidity following cesarean delivery. Tranexamic acid (TXA) has been shown to reduce blood loss when used for the treatment of postpartum hemorrhage; however, its routine prophylactic use during cesarean delivery, particularly in low-risk women, remains controversial. Large randomized trials have demonstrated limited benefit on major maternal outcomes, and data regarding clinically meaningful blood loss reduction and neonatal safety are still inconclusive.\n\nThis randomized controlled trial aims to evaluate the effect of prophylactic tranexamic acid administered after fetal delivery on perioperative blood loss in women undergoing low-risk repeat cesarean delivery. Secondary objectives include the assessment of neonatal outcomes to further evaluate the safety of routine TXA administration in this population.\n\nThe results of this study are expected to provide evidence to inform clinical decision-making regarding the routine use of tranexamic acid in low-risk repeat cesarean deliveries, balancing potential maternal benefits against neonatal safety considerations.",[333],"Cesarean Delivery",[335,336,337],"Tranexamic Acid","Repeat Cesarean Section","Perioperative Blood Loss","2026-01-29",{"date":340,"type":38},"2026-02-05",{"date":342,"type":22},"2026-02-01",{"date":344,"type":22},"2026-09-30",{"name":44,"class":45},{"id":347,"slug":348,"hasResults":12,"nctId":349,"briefTitle":350,"officialTitle":351,"acronym":4,"eligibilityCriteria":352,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":353,"targetDuration":4,"studyType":23,"phases":354,"briefSummary":355,"conditions":356,"keywords":360,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":367,"completionDateStruct":368,"leadSponsor":370,"locationsCount":79},"100621727","nurse-led-early-mobilization-after-colorectal-surgery-100621727","NCT07374380","Nurse-Led Early Mobilization After Colorectal Surgery","Effect of a Nurse-Led Early Mobilization Protocol on Colorectal Surgery Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Scheduled for elective colorectal surgery (e.g., procedures related to\n* colorectal cancer, diverticulitis, or inflammatory bowel disease \\[IBD\\])\n* Able to ambulate independently preoperatively\n* Medically and cognitively able to participate in a mobilization protocol\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Undergoing emergency colorectal surgery\n* Patients requiring postoperative intensive care unit (ICU) admission\n* Severe cognitive impairment or psychiatric disorders that may affect participation\n* Musculoskeletal or neurological conditions that impair mobility\n* Inability to understand study instructions due to language or communication barriers",{"count":169,"type":22},[25],"This study was designed to evaluate the effectiveness of a nurse-led early mobilization protocol on postoperative recovery outcomes in patients undergoing elective colorectal surgery. The outcomes assessed include walking distance, mobility levels, gastrointestinal function (time to first flatus and first defecation), nausea, vomiting, comfort, fatigue, time to initiation of oral intake, patient satisfaction, incidence of postoperative complications, and length of hospital stay.\n\nResearch Question:\n\nIn patients undergoing colorectal surgery (P), does a nurse-led early mobilization protocol (I), compared with standard mobilization practices (C), improve postoperative recovery outcomes (O), including walking distance, mobility levels, gastrointestinal function (time to first flatus and first defecation), nausea, vomiting, comfort, fatigue, time to initiation of oral intake, patient satisfaction, postoperative complication rates, and length of hospital stay?",[357,358,359,178],"Colorectal Surgery","Early Mobilization","Postoperative Care",[361,362,363],"colorectal surgery","early mobilization","Nurse-Led Intervention","2026-01-25",{"date":366,"type":38},"2026-01-28",{"date":156,"type":22},{"date":369,"type":22},"2026-12-29",{"name":44,"class":45},{"id":372,"slug":373,"hasResults":12,"nctId":374,"briefTitle":375,"officialTitle":376,"acronym":4,"eligibilityCriteria":377,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":378,"targetDuration":4,"studyType":23,"phases":380,"briefSummary":381,"conditions":382,"keywords":386,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":389,"startDateStruct":391,"completionDateStruct":392,"leadSponsor":394,"locationsCount":4},"100619431","effect-of-preoperative-abdominal-effleurage-on-postoperative-constipation-100619431","NCT07344532","Effect of Preoperative Abdominal Effleurage on Postoperative Constipation","The Effect of Preoperative Abdominal Superficial Effleurage Training on the Development of Postoperative Constipation in Patients Undergoing Abdominal Surgery","Inclusion Criteria:\n\n* Patients scheduled to undergo abdominal surgery\n* Patients who are able to communicate verbally\n* Patients who agree to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* Patients with preoperative constipation\n* Patients with known gastrointestinal diseases affecting bowel motility\n* Patients who are unable to perform abdominal superficial effleurage\n* Patients with cognitive impairment or communication difficulties\n* Patients who refuse to participate in the study",{"count":379,"type":22},42,[25],"This randomized controlled study aims to evaluate the effect of preoperative abdominal superficial effleurage training on the development of postoperative constipation in patients undergoing abdominal surgery. Participants will be randomly assigned to an intervention group receiving abdominal superficial effleurage training in addition to routine care or to a control group receiving routine care only. The effleurage technique will be taught preoperatively and performed by patients postoperatively. Postoperative constipation will be assessed on the 10th postoperative day using the Bristol Stool Form Scale. The findings of this study are expected to contribute to non-pharmacological nursing interventions for the prevention of postoperative constipation.",[383,384,385],"Constipation","Abdominal Surgery","Postoperative Constipation",[385,384,387,388],"Abdominal Effleurage","Non-Pharmacological Intervention",{"date":390,"type":38},"2026-01-27",{"date":233,"type":22},{"date":393,"type":22},"2026-09-10",{"name":44,"class":45},{"id":396,"slug":397,"hasResults":12,"nctId":398,"briefTitle":399,"officialTitle":399,"acronym":4,"eligibilityCriteria":400,"healthyVolunteers":248,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":401,"targetDuration":4,"studyType":23,"phases":403,"briefSummary":404,"conditions":405,"keywords":410,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":415,"lastUpdatePostDateStruct":416,"startDateStruct":418,"completionDateStruct":420,"leadSponsor":422,"locationsCount":79},"100620762","evaluation-of-the-effectiveness-of-using-virtual-reality-glasses-in-prehospital-intervention-training-for-crush-syndrome-100620762","NCT07361835","Evaluation of the Effectiveness of Using Virtual Reality Glasses in Prehospital Intervention Training for Crush Syndrome","Inclusion Criteria:\n\nBeing a second-year student currently enrolled in the first and emergency aid program at Muğla Sıtkı Koçman University.\n\nVoluntarily providing written informed consent to participate in the study. Having basic technological literacy to use virtual reality equipment.\n\nExclusion Criteria:\n\nFirst-year students who have not yet reached the relevant stage of the curriculum.\n\nStudents who have previously participated in a similar virtual reality-based crush syndrome simulation.\n\nStudents with medical conditions that may be aggravated by VR use (e.g., severe motion sickness, history of seizures).\n\nRefusal to participate voluntarily.",{"count":402,"type":22},61,[25],"This research is a randomized controlled study designed to develop and evaluate the effectiveness of a video-based virtual reality (VR) simulation for prehospital intervention training of crush syndrome for paramedic students. The study aims to examine the impact of VR simulation on knowledge levels, satisfaction, and sense of presence among second-year first and emergency aid students at Muğla Sıtkı Koçman University.",[406,228,407,408,409],"Rhabdomyolysis","Emergency Medical Services","Disaster Medicine","Crush Injuries",[411,412,413,414],"Prehospital Care","Paramedics","Simulation Training","Virtual Reality Simulation","2026-01-21",{"date":417,"type":38},"2026-01-23",{"date":419,"type":22},"2026-02",{"date":421,"type":22},"2026-05",{"name":44,"class":45},{"id":424,"slug":425,"hasResults":12,"nctId":426,"briefTitle":427,"officialTitle":428,"acronym":429,"eligibilityCriteria":430,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":431,"targetDuration":4,"studyType":23,"phases":433,"briefSummary":434,"conditions":435,"keywords":439,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":444,"lastUpdatePostDateStruct":445,"startDateStruct":447,"completionDateStruct":449,"leadSponsor":451,"locationsCount":4},"100620489","mobile-education-and-comfort-in-ostomy-patients-100620489","NCT07358286","MOBILE EDUCATION AND COMFORT IN OSTOMY PATIENTS","THE EFFECT OF KOLCABA'S COMFORT THEORY-BASED MOBILE EDUCATION ON COMFORT LEVELS OF OSTOMY PATIENTS: A RANDOMIZED CONTROLLED TRIAL","STOMA-PLUS","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Patients with a stoma (colostomy or urostomy)\n* Ability to use a smartphone or mobile device\n* Willingness to participate in the study\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Cognitive impairment that prevents understanding of the study procedures\n* Severe psychiatric disorders\n* Inability to use mobile technology\n* Participation in another interventional study during the study period",{"count":432,"type":22},68,[25],"Purpose of the Study\n\nThis study aims to understand whether a mobile education program can improve comfort levels in people living with a stoma. A stoma is a surgical opening created on the abdomen to allow stool or urine to leave the body. Living with a stoma can affect daily life in many ways, including physical comfort, emotional well-being, social life, and the home environment.\n\nThe education program used in this study is based on Kolcaba's Comfort Theory. This theory focuses on comfort as a whole and includes physical, emotional, social, and environmental aspects of a person's life. The study will compare people who receive mobile education with those who receive standard hospital care only.\n\nWho Can Take Part\n\nAdults aged 18 years and older who are scheduled to have colostomy, ileostomy, or urostomy surgery may take part in this study. Participants must be able to communicate in Turkish, read and understand written information, and agree to join the study voluntarily.\n\nPeople with severe cognitive problems, serious communication difficulties, or major vision or hearing problems will not be included.\n\nWhat Will Happen in the Study\n\nParticipants will be randomly assigned to one of two groups:\n\nMobile Education Group\n\nStandard Care Group\n\nBoth groups will receive routine care provided by the hospital.\n\nParticipants in the mobile education group will also receive access to a mobile application designed specifically for people with a stoma. This application includes:\n\nEasy-to-understand information about stoma care\n\nAnimated educational videos showing step-by-step stoma care practices\n\nGuidance on skin care, pouch changing, and hygiene\n\nInformation on common problems and when to seek medical help\n\nReminders to support daily stoma care routines\n\nThe mobile application can be used on smartphones and does not include diagnosis or treatment. It is for education and support only.\n\nParticipants in the standard care group will receive usual hospital education and care. After the study is completed, they will also be offered the mobile education program.\n\nWhat Participants Will Be Asked to Do\n\nAll participants will be asked to answer questionnaires that measure comfort levels at several time points:\n\nBefore surgery\n\nOne day after surgery\n\nFifteen days after discharge (by phone)\n\nOne month after surgery (during a clinic visit)\n\nParticipants in the mobile education group will be shown how to use the application and may use it as often as they wish. Researchers may contact participants to ask about their experience using the app and to identify any difficulties.\n\nPossible Benefits\n\nParticipants may gain better understanding of stoma care and feel more confident managing daily life with a stoma. The mobile education program may help reduce discomfort, support emotional well-being, and improve overall quality of life.\n\nThe results of this study may help healthcare professionals develop better education tools and support programs for people living with a stoma.\n\nRisks and Safety\n\nThis study does not involve experimental medical treatments. The mobile application provides education only. Personal data will not be collected through the app, and all information will be kept confidential. Participants may leave the study at any time without affecting their medical care.\n\nWhy This Study Is Important\n\nAccess to stoma care education can be limited due to time constraints, staff availability, and hospital resources. Mobile education may provide an easy and accessible way for people to receive reliable information whenever they need it.\n\nThis study will help determine whether a comfort-focused mobile education program can support people living with a stoma and improve their overall comfort and well-being.",[436,437,438],"Stoma","Ostomy","Mobile Application",[440,441,442,443],"Ostomy Care","Mobile Health","Kolcaba's Comfort Theory","Nursing","2026-01-14",{"date":446,"type":38},"2026-01-22",{"date":448,"type":22},"2026-01",{"date":450,"type":22},"2026-06",{"name":44,"class":45},{"id":453,"slug":454,"hasResults":12,"nctId":455,"briefTitle":456,"officialTitle":457,"acronym":4,"eligibilityCriteria":458,"healthyVolunteers":248,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":459,"targetDuration":4,"studyType":23,"phases":461,"briefSummary":462,"conditions":463,"keywords":465,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":469,"lastUpdatePostDateStruct":470,"startDateStruct":472,"completionDateStruct":474,"leadSponsor":476,"locationsCount":79},"100616409","pediatric-drug-dose-calculation-100616409","NCT07305233","Pediatric Drug Dose Calculation","The Effect of Web-Supported Interactive Learning on the Knowledge Level of Nursing Students on Pediatric Drug Dose Calculation: A Randomized Controlled Study","Inclusion Criteria:\n\nStudents who had a computer or smartphone and students who volunteered to participate in the study were included in the study\n\nExclusion Criteria:\n\nStudents who did not have a computer or smartphone and students who did not complete all stages of the study were excluded from the study.",{"count":460,"type":22},108,[25],"This study is a randomized controlled trial that aimed to investigate the effect of a web-supported interactive learning program on the knowledge level of nursing students about pediatric drug dose calculation.\n\nThe study was conducted at one of Turkey's most established nursing faculties, and 108 students participated in the study. Participants were randomly assigned to study (n:54) and control (n:54) groups. The study group received both a traditional lecture and a Web-supported interactive learning application, while the control group was limited to a traditional lecture-based instruction. The \"Drug Dose Calculation Knowledge Test\", \"Perceived Learning Scale\", and \"Medication Administration Self-Efficacy Scale in Children for Nursing Students\" scales were used to collect the data.",[464],"Drug Dose",[466,467,468],"Pediatric nursing","drug calculation","ınteractive learning","2025-12-12",{"date":471,"type":38},"2025-12-26",{"date":473,"type":38},"2022-10-01",{"date":475,"type":22},"2025-12-31",{"name":44,"class":45},{"id":478,"slug":479,"hasResults":12,"nctId":480,"briefTitle":481,"officialTitle":482,"acronym":4,"eligibilityCriteria":483,"healthyVolunteers":12,"sex":249,"minAge":86,"maxAge":484,"enrollmentInfo":485,"targetDuration":4,"studyType":23,"phases":486,"briefSummary":487,"conditions":488,"keywords":490,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":494,"lastUpdatePostDateStruct":495,"startDateStruct":497,"completionDateStruct":499,"leadSponsor":501,"locationsCount":79},"100611557","efficacy-of-oral-contraceptive-progesterone-and-inositol-on-menstrual-regulation-in-pcos-100611557","NCT07242131","Efficacy of Oral Contraceptive, Progesterone, and Inositol on Menstrual Regulation in PCOS","Comparison of the Efficacy of Oral Contraceptive, Progesterone, and Inositol Use in Regulating Menstrual Cycles in Patients With Polycystic Ovary Syndrome (PCOS)","Inclusion Criteria:\n\n* Female participants aged 18 to 40 years.\n* Diagnosed with polycystic ovary syndrome (PCOS) according to the ESHRE\u002FASRM (Rotterdam) criteria (presence of at least two of the following: oligo\u002Fanovulation, clinical or biochemical hyperandrogenism, polycystic ovarian morphology).\n* No significant comorbid systemic disease.\n* Willingness to participate and ability to provide written informed consent.\n* Regular follow-up availability for at least 6 months.\n\nExclusion Criteria:\n\n* Known hepatic, renal, cardiovascular, or endocrine disorders other than PCOS.\n* Pregnancy or current use of hormonal therapy within the past 3 months.\n* History of thromboembolic disease, breast cancer, or other contraindications to hormonal treatment.\n* Inability to adhere to follow-up visits or treatment regimen.\n* Severe cognitive or communication impairment that prevents proper consent or data collection.\n* Known allergy or hypersensitivity to any component of the study drugs.\n* Participation in another interventional study within the past 3 months.","40 Years",{"count":278,"type":22},[25],"This cross-sectional study aims to compare the effectiveness of oral contraceptives, oral progesterone (didrogesterone), and inositol in regulating menstrual cycles among women diagnosed with polycystic ovary syndrome (PCOS).\n\nPCOS is a common endocrine disorder affecting reproductive-aged women and is associated with menstrual irregularities, hyperandrogenism, and polycystic ovarian morphology. While oral contraceptives are the mainstay of treatment, their use may be contraindicated in patients with cardiovascular risk factors, liver dysfunction, or in those who desire pregnancy.\n\nThis study investigates whether oral progesterone and myo-inositol can serve as effective and safer alternatives for menstrual regulation and improvement of ovarian morphology and hyperandrogenic symptoms.\n\nA total of 150 women aged 15-40 years with a diagnosis of PCOS will be enrolled and divided into three equal groups:\n\nGroup 1: Oral contraceptive users\n\nGroup 2: Oral progesterone users\n\nGroup 3: Inositol users The study will assess changes in menstrual regularity, ovarian morphology (via ultrasound), and clinical features such as hirsutism and acne before and after treatment.",[489],"Polycystic Ovary Syndrome (PCOS)",[491,492,493],"Polycystic Ovary Syndrome","Menstrual Cycle","Didrogesterone","2025-12-10",{"date":496,"type":38},"2025-12-18",{"date":498,"type":38},"2025-12-01",{"date":500,"type":22},"2026-06-01",{"name":44,"class":45},{"id":503,"slug":504,"hasResults":12,"nctId":505,"briefTitle":506,"officialTitle":507,"acronym":508,"eligibilityCriteria":509,"healthyVolunteers":12,"sex":249,"minAge":250,"maxAge":276,"enrollmentInfo":510,"targetDuration":4,"studyType":23,"phases":512,"briefSummary":513,"conditions":514,"keywords":516,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":520,"lastUpdatePostDateStruct":521,"startDateStruct":523,"completionDateStruct":524,"leadSponsor":526,"locationsCount":79},"100610345","endoscopic-tissue-cutting-and-abdominal-extraction-device-vs-conventional-cold-scalpel-100610345","NCT07226375","Endoscopic Tissue Cutting and Abdominal Extraction Device vs. Conventional Cold Scalpel","Comparison of Endoscopic Tissue Cutting and Abdominal Extraction Device With Conventional Cold Scalpel","SOLENDO-1","Inclusion Criteria:\n\n* Planned laparoscopic hysterectomy\n* Estimated uterine weight of 500 g or more\n\nExclusion Criteria:\n\n* Sexual inactivity",{"count":511,"type":22},84,[25],"The aim of the study is to compare the surgical tissue removal success of the endoscopic tissue cutting device, which was designed by the conductor and developed with the support of TUBITAK-1512 project and for which Turkish and European patent applications were made, with the conventional cold scalpel. Laparoscopic surgeries are performed through incisions ranging from 0.5 cm to 1 cm. After the operation, much larger masses need to be removed from the abdomen compared to these incisions. Currently, in laparoscopic surgery, masses are removed from the abdomen by cutting them into pieces with a scalpel, using electrical devices called power morcellators that are used to cut the tissue\u002Fmass with rotational movement and remove it from the abdomen, and directly removing the mass from the abdomen through an incision made as large as the size of the mass. Trying to remove large tissues\u002Fmass by dissecting them with a scalpel through incisions that are 1.5-2 cm wide and limit the surgeon's range of motion is quite laborious, tiring, time-consuming and risky. In the use of Power Morcellator disintegrator devices, there is a risk of the pieces of the mass spreading into the abdomen while cutting and separating the tissue\u002Fmass that is being removed into small pieces due to the rotational movement in the working principle. In operations where the Power Morcellator device is used, if the removed tissue is malignant (cancerous), the patient faces the risk of metastasis spreading to the entire abdomen. Due to these risks, the use of power morcellator devices has been completely banned in the United States, and in European Union countries, it has been required that the device be operated in protective bags. The invention is a medical device that will allow large masses to be removed quickly, safely and easily through small incisions in closed surgeries. The device offers an effective solution to the problems of the current technique.\n\nWithin the scope of the study, the morcellator scissors and the scalpel, which are designed and started to be mass-produced, will be compared in the morcellation (removal by separating into pieces) process to be performed during the removal of the mass from the vagina after laparoscopic hysterectomy surgeries, and the morcellation time, possible complications and the possible effects of the device to be used on the case will be investigated.",[515],"Laparoscopic Hysterectomy",[517,518,519],"laparoscopic hysterectomy","morcellation","tissue extraction","2025-11-13",{"date":522,"type":38},"2025-11-14",{"date":520,"type":38},{"date":525,"type":22},"2026-12-17",{"name":44,"class":45},{"id":528,"slug":529,"hasResults":12,"nctId":530,"briefTitle":531,"officialTitle":532,"acronym":533,"eligibilityCriteria":534,"healthyVolunteers":12,"sex":17,"minAge":535,"maxAge":53,"enrollmentInfo":536,"targetDuration":4,"studyType":23,"phases":537,"briefSummary":538,"conditions":539,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":317,"lastUpdatePostDateStruct":542,"startDateStruct":544,"completionDateStruct":545,"leadSponsor":546,"locationsCount":4},"100608508","virtual-reality-for-pain-fear-and-physiological-responses-during-pediatric-venous-catheterization-100608508","NCT07202468","Virtual Reality for Pain, Fear, and Physiological Responses During Pediatric Venous Catheterization","\"The Effect of Two Different Applications Shown With Virtual Reality Glasses During Peripheral Venous Catheterization on Pain, Fear, and Physiological Parameters in Children\"","VR-PainKids","Inclusion Criteria:\n\n* Children aged 7-12 years\n* Scheduled for day surgery in the pediatric surgery unit\n* Undergoing first-time peripheral intravenous catheterization in the clinic\n* Both child and parent provide informed consent\u002Fassent to participate\n* Child and parent have no speech or visual impairment\n\nExclusion Criteria:\n\n* Children younger than 7 or older than 12 years\n* Not scheduled for day surgery in the pediatric surgery unit\n* Child or parent declining participation\n* Presence of speech or visual impairment in child or parent","7 Years",{"count":278,"type":22},[25],"This study aims to evaluate the effect of two different virtual reality (VR) applications on children's pain, fear, and physiological parameters during peripheral intravenous catheterization. Children between the ages of 7 and 12 who are scheduled for day surgery in the pediatric surgery unit will be randomly assigned to one of three groups: (1) Aquarium VR video, (2) Kaleidoscope VR video, or (3) routine care control group.\n\nVR interventions will begin 2-3 minutes before the procedure and will continue throughout catheter insertion. The primary outcomes will include pain and fear levels measured by validated pediatric scales, while secondary outcomes will focus on physiological parameters such as heart rate, respiratory rate, body temperature, and oxygen saturation.\n\nThe purpose of this research is to determine whether distraction with VR technology can reduce procedural pain and fear in children, improve their cooperation during invasive procedures, and support atraumatic care practices in pediatric nursing.",[540,541],"Pain Management","Fear and Anxiety",{"date":543,"type":38},"2025-10-01",{"date":181,"type":22},{"date":342,"type":22},{"name":44,"class":45},{"id":548,"slug":549,"hasResults":12,"nctId":550,"briefTitle":551,"officialTitle":552,"acronym":553,"eligibilityCriteria":554,"healthyVolunteers":12,"sex":249,"minAge":112,"maxAge":555,"enrollmentInfo":556,"targetDuration":4,"studyType":141,"phases":4,"briefSummary":558,"conditions":559,"keywords":568,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":575,"lastUpdatePostDateStruct":576,"startDateStruct":578,"completionDateStruct":580,"leadSponsor":582,"locationsCount":79},"100607843","sexual-dysfunction-in-women-with-multiple-sclerosis-ms-100607843","NCT07193823","Sexual Dysfunction in Women With Multiple Sclerosis (MS)","Sexual Dysfunction Prevalence and Its Relationship With Various Factors in Women With Multiple Sclerosis","MS","Inclusion Criteria:\n\n* Female patients aged 25-50 years\n* Literate and able to comprehend written and spoken instructions\n* Diagnosed with relapsing-remitting form of multiple sclerosis\n* Having a continuous\u002Fregular sexual partner\n* Expanded Disability Status Scale (EDSS) score ≤ 5\n* At least 3 months since the last relapse\n* Sexually active within the past 3 months\n* Spasticity level \\\u003C grade 2 according to the Modified Ashworth Scale\n\nExclusion Criteria:\n\n* Pregnancy\n* Illiteracy or inability to understand spoken or written instructions\n* Absence of a continuous\u002Fregular sexual partner\n* Expanded Disability Status Scale (EDSS) score \\> 5\n* Not sexually active within the past 3 months\n* Spasticity level ≥ grade 2 according to the Modified Ashworth Scale","50 Years",{"count":557,"type":22},140,"Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with MS. The secondary objective is to evaluate the relationship between sexual dysfunction and fatigue, depression, anxiety, overactive bladder symptoms, and cognitive dysfunction.\n\nFor this purpose, the following validated instruments will be used: the Female Sexual Function Index (FSFI) to assess sexual dysfunction, the Brief International Cognitive Assessment for MS (BICAMS) to evaluate cognitive function, the Hospital Anxiety and Depression Scale (HADS) to assess depression and anxiety, the Fatigue Severity Scale (FSS) to measure fatigue, and the Overactive Bladder Questionnaire (OAB-V8) to evaluate overactive bladder symptoms.",[560,561,562,563,564,565,59,566,567],"Multiple Sclerosis","Multiple Sclerosis (MS) - Relapsing-remitting","Fatigue in Multiple Sclerosis","Sexual Disfunction","Cognitive Dysfunction","Depression","Overactive Bladder","Fatigue",[569,570,571,572,66,573,574],"multiple sclerosis","sexual dysfunction","cognitive dysfunction","depression","overactive bladder","fatigue","2025-09-22",{"date":577,"type":38},"2025-09-26",{"date":579,"type":38},"2024-07-16",{"date":581,"type":22},"2025-11",{"name":44,"class":45},{"id":584,"slug":585,"hasResults":12,"nctId":586,"briefTitle":587,"officialTitle":588,"acronym":589,"eligibilityCriteria":590,"healthyVolunteers":248,"sex":249,"minAge":86,"maxAge":250,"enrollmentInfo":591,"targetDuration":4,"studyType":23,"phases":593,"briefSummary":594,"conditions":595,"keywords":597,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":603,"lastUpdatePostDateStruct":604,"startDateStruct":605,"completionDateStruct":607,"leadSponsor":609,"locationsCount":79},"100598912","marmet-and-oxytocin-massage-for-breast-milk-increase-100598912","NCT07077655","Marmet and Oxytocin Massage for Breast Milk Increase","The Effectiveness of the Marmet Technique and Oxytocin Massage on Breast Milk Quantity in Mothers Who Have Undergone Cesarean Section","RCT","Inclusion Criteria:\n\n* Aged between 18-35 years\n* Literate\n* Fluent in Turkish\n* Volunteering to participate in the study\n* Primiparous (first-time mothers)\n* Within the first 2 hours postpartum (mothers performing their first breastfeeding under researcher supervision)\n* Have a single baby with an appropriate birth weight for gestational age (\\>2500 gr)\n* Have their baby with them\n* Received spinal anesthesia\n* Neither the mother nor the baby has any acute or chronic illness\n* Exclusively breastfeeding their baby\n* Had a term (37 weeks gestation or more) and cesarean delivery\n* Experienced no complications after the cesarean section\n* No issues preventing breastfeeding\n* Willing to breastfeed\n\nExclusion Criteria:\n\n* Are under 18 or over 35 years old\n* Are multiparous (have given birth before)\n* Are encountered more than 2 hours postpartum\n* Received general anesthesia\n* Have any acute or chronic illness themselves or their baby\n* Have conditions requiring mother and baby to be separated\n* Report experiencing severe pain\n* Formula-feed their baby or consume any milk-increasing medication or tea\n* Gave birth before 37 weeks gestation or had a vaginal delivery\n* Have an anatomical breast issue (absence of nipple, inverted nipple)\n* Have swelling, ecchymosis, or wounds on their back (for the oxytocin massage group)\n* Have a baby with a congenital anomaly\n* Have an issue preventing breastfeeding\n* Have a psychological issue\n* Are unwilling to breastfeed",{"count":592,"type":22},123,[25],"This study is designed as a randomized controlled single-blind experimental study to examine the effectiveness of the oxytocin massage and Marmet technique applied to mothers who have undergone cesarean section on breast milk quantity and maternal state anxiety levels. The hypotheses of the study are as follows:\n\nH0.1. There is no difference in the amount of breast milk among mothers in the Marmet technique, oxytocin massage, and control (placebo) groups.\n\nH1.1. There is a difference in the amount of breast milk among mothers in the Marmet technique, oxytocin massage, and control (placebo) groups.\n\nH0.2. There is no difference in the state anxiety scale scores among mothers in the Marmet technique, oxytocin massage, and control (placebo) groups.\n\nH1.2. There is a difference in the state anxiety scale scores among mothers in the Marmet technique, oxytocin massage, and control (placebo) groups.\n\nParticipants:\n\nMarmet technique, oxytocin massage, and control (placebo) groups will be informed about the study and asked to provide their consent. Participants will complete the descriptive questionnaire. Colostrum status will be checked and marked as \"present\" or \"absent\" on the \"Breast Milk, Vital Signs, and Pain Level Form.\" Under researcher supervision, the mother will breastfeed her baby. Afterward, the State Anxiety Inventory will be administered.\n\nTwo hours later, mothers will express milk using a hospital-grade pump, with 15 minutes on each breast (total 30 minutes). Milk volume, vital signs, pain levels, and milk flow rate will be recorded on the relevant form. Following this, mothers in the Marmet group will receive 10 minutes of the Marmet technique, mothers in the oxytocin group will receive 5 minutes of oxytocin massage, and mothers in the control group will receive 5 minutes of light touch on their wrists and shoulders. Immediately after, milk expression will again be performed with 15 minutes per breast (30 minutes total). The State Anxiety Inventory will be re-administered, and milk amount, vital signs, pain levels, and flow rate will be recorded again.\n\nAll mothers will express milk using a hospital-grade breast pump, and the expression duration is standardized as 15 minutes per breast (30 minutes total) based on the literature. Two expressions will be performed - one before and one immediately after the intervention. Expressed milk will not be discarded and will instead be used to feed the babies via spoon or syringe under the researcher's supervision.",[596],"Healhty",[598,599,600,601,602],"breastmilk","mother","massage techniques","marmet technique","oxytocin massage","2025-09-16",{"date":575,"type":38},{"date":606,"type":38},"2025-08-25",{"date":608,"type":22},"2025-12-30",{"name":44,"class":45},{"id":611,"slug":612,"hasResults":12,"nctId":613,"briefTitle":614,"officialTitle":615,"acronym":616,"eligibilityCriteria":617,"healthyVolunteers":12,"sex":17,"minAge":276,"maxAge":4,"enrollmentInfo":618,"targetDuration":4,"studyType":141,"phases":4,"briefSummary":620,"conditions":621,"keywords":626,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":631,"lastUpdatePostDateStruct":632,"startDateStruct":634,"completionDateStruct":636,"leadSponsor":638,"locationsCount":4},"100605530","incidence-and-factors-of-functional-decline-after-emergency-department-discharge-in-older-adults-with-falls-100605530","NCT07163715","Incidence and Factors of Functional Decline After Emergency Department Discharge in Older Adults With Falls","Prospective Cohort Study on the Incidence and Associated Factors of Decline in Activities of Daily Living Among Older Adults Discharged From the Emergency Department After a Fall","FALL-ADL","Inclusion Criteria:\n\n* Age ≥ 65 years\n* Presentation to the emergency department with a simple (non-injurious) fall\n* Discharged from the ED without hospitalization\n* Cognitively able to answer online or telephone follow-up interviews\n\nExclusion Criteria:\n\n* Falls due to traumatic events other than simple falls\n* Hospital admission required after the fall\n* Presence of acute confusion, dementia, or other severe cognitive impairment\n* Inability to access online or telephone follow-up during the 30-day study period",{"count":619,"type":22},280,"The goal of this observational study is to learn about changes in activities of daily living (ADL) in older adults after being discharged from the emergency department (ED) following a fall.\n\nThe main questions this study aims to answer are:\n\nHow often do older adults experience a decline in their ability to perform daily activities after being discharged from the ED for a fall? What health or lifestyle factors (such as frailty, medications, physical activity, or fear of falling) are related to this decline? Participants will be 65 years or older, admitted to the ED for a simple fall, and discharged without hospitalization. At the time of their ED visit, participants will be asked questions about their health, medications, activity level, and daily functioning. They will then be contacted online or by phone at 7 days and 30 days after discharge to answer follow-up questions.\n\nThis study will help identify how common functional decline is after falls in older adults discharged from the ED, and which factors may predict higher risk. These findings could help improve follow-up care and prevention strategies for older patients.",[622,623,624,625],"Fall","Daily Activities","Functional Decline","Older Adults (65 Years and Older)",[627,628,629,630],"Falls","Decline fictional status","Decline daily activities","Emergency medicine","2025-09-02",{"date":633,"type":38},"2025-09-09",{"date":635,"type":22},"2025-09-05",{"date":637,"type":22},"2025-12-05",{"name":44,"class":45},{"id":640,"slug":641,"hasResults":12,"nctId":642,"briefTitle":643,"officialTitle":644,"acronym":4,"eligibilityCriteria":645,"healthyVolunteers":12,"sex":249,"minAge":86,"maxAge":276,"enrollmentInfo":646,"targetDuration":4,"studyType":23,"phases":648,"briefSummary":649,"conditions":650,"keywords":652,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":654,"lastUpdatePostDateStruct":655,"startDateStruct":657,"completionDateStruct":659,"leadSponsor":660,"locationsCount":79},"100514020","investigation-of-the-effect-of-distention-medium-temperature-on-image-quality-hyponatremia-risk-and-post-operative-pain-in-operative-hysteroscopy-100514020","NCT05973045","Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk, and Post-operative Pain in Operative Hysteroscopy","Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk and Post-operative Pain in Operative Hysteroscopy","Inclusion Criteria:\n\n* To be planned for operative hysteroscopy due to an endometrial polyp or type 0-1 myoma in the range of 2-3 cm\n* Having a vaginal delivery at least once before\n* Ability to communicate adequately in Turkish or English\n\nExclusion Criteria:\n\n* Pregnancy\n* Active vaginal, and cervical infection",{"count":647,"type":22},244,[25],"Minimally invasive applications are seen as the gold standard in today's gynecology practice and are frequently preferred by both patients and physicians. Less pain, shorter hospital stays, and better cosmetic results brought about by minimally invasive applications further increase their preference. One of these approaches is hysteroscopic interventions. Although hysteroscopy is a well-defined method, current research has focused on further reduction of pain. One of these methods is to warm the distention media at body temperature. theTaim of this study was to examine the effect of distention medium temperature on image quality, hyponatremia risk, and post-operative pain in operative hysteroscopy.",[651],"Post-operative Pain",[653],"hysteroscopy","2025-08-11",{"date":656,"type":38},"2025-08-14",{"date":658,"type":38},"2023-09-01",{"date":344,"type":22},{"name":44,"class":45},{"id":662,"slug":663,"hasResults":12,"nctId":664,"briefTitle":665,"officialTitle":666,"acronym":667,"eligibilityCriteria":668,"healthyVolunteers":12,"sex":249,"minAge":86,"maxAge":4,"enrollmentInfo":669,"targetDuration":4,"studyType":23,"phases":670,"briefSummary":671,"conditions":672,"keywords":676,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":679,"lastUpdatePostDateStruct":680,"startDateStruct":682,"completionDateStruct":684,"leadSponsor":686,"locationsCount":79},"100599201","home-based-transcutaneous-remotely-monitored-posterior-tibial-neuromodulation-100599201","NCT07081412","Home-Based Transcutaneous Remotely Monitored Posterior Tibial Neuromodulation","Home-Based Transcutaneous Remotely Monitored Posterior Tibial Neuromodulation System in Overactive Bladder: A Randomized Controlled Trial","TRIP-HOME","Inclusion Criteria:\n\n1. Patients who are ≥18 years old and female patients diagnosed with OAB\\* in Urology or Urogynecology outpatient clinics and who meet the inclusion criteria\n2. Being able to continue their T-PTNS\\*\\* treatment at home with the mobile application and accepting this,\n3. Having a smartphone compatible with the application for T-PTNS and being able to use the application\n4. Agreeing to be followed up for one year after treatment,\n5. Having stopped all antimuscarinics for at least two weeks,\n6. Being able to stand and use the toilet independently without difficulty,\n7. Volunteers who are willing to participate, have been informed about the study and have given signed informed consent, stating that they can comply with the requirements and restrictions listed in the informed consent form (ICP) and this protocol.\n\nExclusion Criteria:\n\n1. Patients under the age of 18\n2. Patients who are pregnant according to the results of a pregnancy test with urine or blood test, or who are planning a pregnancy during the study period, or who are breastfeeding\n3. Patients diagnosed with neurogenic bladder\n4. Patients with Dabetes Mellitus whose blood sugar cannot be controlled\n5. Patients with a history of allergic reactions on the skin\n6. Cases with prolapse greater than Stage-2 according to the POP-Q staging system and extending beyond the hymen\n7. Cases with a PVR evaluation of 100 ml and above with USG\n8. Contraindications for T-PTNS treatment (patients with pacemakers, implantable defibrillators or metal prostheses\n9. Patients with urinary tract infection\\*\n10. Having had botox applied to the bladder or pelvic floor muscles within the last year\n11. Having had a previous surgery related to the pelvic floor\n12. Current TENS use in the pelvic region, back or legs\n13. Having received PTNS treatment before\n14. Use of Interstim or Bion\n15. Those who do not accept the treatment or follow-up to be performed\n16. Those who may have problems complying with the requirements of the study plan\n17. Negative benefit\u002Frisk ratio determined by the investigator\n18. Those who have been included in any other clinical trial or use of investigational drug\u002Fdevice therapy within 30 days before the study visit",{"count":88,"type":22},[25],"To record the T-PTNS device (SmartUric) treatment performed by the patient at home via a mobile application in a remotely monitorable, secure and interactive manner with registration notes and a sham control group.",[673,674,675],"Overactive Bladder Syndrome","Overactive Bladder (OAB)","Transcutaneous Posterior Tibial Nerve Stimulation (TTNS)",[573,677,678,95],"neuromodulation","Posterior Tibial Nerve Stimulation","2025-07-22",{"date":681,"type":38},"2025-07-23",{"date":683,"type":38},"2025-06-24",{"date":685,"type":22},"2026-12-31",{"name":44,"class":45},""]