[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Emporia State University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100634573","miles-for-mental-health-100634573",false,"NCT07541443","Miles for Mental Health","Miles for Mental Health: The Impact of Cardiovascular Fitness on Mental Health Outcomes","Inclusion Criteria:\n\n* Age 18+ years\n* Generalized anxiety and\u002For depressive disorder diagnosis\n* Able to exercise without use of ambulatory device\n* Willing and able to attend a minimum of 2 group exercise sessions weekly\n\nExclusion Criteria:\n\n* Myocardial infarction or symptoms of coronary artery disease in the last 2yrs\n* Uncontrolled hypertension within the last 6 months\n* Cancer in the last 2yrs (except non-metastatic basal or squamous cell carcinoma)\n* Significant pain or musculoskeletal disorder that would prohibit participation in an exercise program\n* Possible\u002Fprobably dementia or mild cognitive impairment (MCI) base on adjudication\n* Physician concern regarding safety or completion of the study","ALL","18 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","Common mental health disorders, like anxiety and depression, are widespread among the American population. The prevalence of mental health disorders among adults continues has consistently increased from previous decades and is now a major public health challenge. Data shows that 1 in 5 Americans regularly report feeling depressed. Therapy is supported as an effective means of treating mental anxiety and depression, and lessening their severity. But therapy is expensive and not always covered by insurance. It is well known that exercise provides physiological and psychological benefits to those suffering from mental health disorders. However, prescribing and monitoring exercise can be challenging, if not impossible, for mental health practitioners, and individuals often are unsure how to begin an exercise program on their own. Studies that have investigated the impact on exercise on mental health have delivered exercise using a traditional clinical trial exercise structure, where exercise is completed by the client\u002Fpatient under the supervision of a professional. This structure, while beneficial, does not always transfer well to real-world settings. Working one-on-one with an exercise professional poses financial and scheduling barriers for most. Few, if any, studies have used group exercise and group therapy to address mental health concerns. This study aims to combine cardiovascular exercise with group therapy to investigate the impact of cardiovascular fitness on mental health outcomes among Rural dwelling adults living with generalized anxiety and\u002For depressive disorders.",[26,27],"Generalized Anxiety Disorder (GAD)","Depressive and Anxiety Disorders",[29,30,31,32,33],"cardiovascular fitness","mental health","anxiety","depression","group exercise","NOT_YET_RECRUITING","2026-04-14",{"date":37,"type":38},"2026-04-21","ACTUAL",{"date":40,"type":20},"2026-06-01",{"date":42,"type":20},"2026-12-31",{"name":44,"class":45},"Emporia State University","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100567409","exercise-from-afar-progressing-at-risk-individuals-to-independent-exercise-100567409","NCT06667817","Exercise From Afar: Progressing At Risk Individuals to Independent Exercise","Exercise From Afar: Progressing At-Risk Rural Adults to Effective Independent Exercise for Dementia Risk Reduction","Inclusion Criteria:\n\n* 40 to 70 years of age\n* Characterized as underactive by the TAPA\n* Able to read and converse in English\n* Willing and able to install an application on their smart phone\n\nExclusion Criteria:\n\n* Myocardial infarction or symptoms of coronary artery disease in the last 2yrs\n* Uncontrolled hypertension within the last 6 months\n* Cancer in the last 2yrs (except non-metastatic basal or squamous cell carcinoma)\n* Significant pain or musculoskeletal disorder that would prohibit participation in an exercise program\n* Possible\u002Fprobably dementia or mild cognitive impairment (MCI) base on adjudication\n* Physician concern regarding safety or completion of the study",true,"40 Years","70 Years",{"count":57,"type":20},50,[23],"The purpose of this study is to investigate the efficacy of a technology-driven independent exercise program on health outcomes associated with dementia risk among underactive rural adults.\n\nUnderactive adults (n=50), ages 40-70 years, from federally designated rural and frontier Kansas counties will be recruited to participate in this study. Specific inclusionary and exclusionary criteria will be used to screen potential participants and determine eligibility. Following recruitment and screening, participants will complete baseline physical fitness and health assessments, supervised by the research team. Following completion of baseline assessments, a personal training\u002Ffitness app will be employed to design and deliver exercise programming and track exercise participation, adherence and progression over the course of the study. All prescribed exercise will follow national governing body recommendations and include specific exercises found in previous work to be beneficial for physical health and brain plasticity. The study team will record exercise instruction videos that can be accessed by all participants at any time throughout the study. The particular app used will allow the research team to organize exercise videos into structured training sessions, allowing participants to exercise on their own, at the location of their choice, with ample instruction. The app will also allow participants to record themselves performing various exercises and send them to the research team for analysis of technique and safety. Communication between study personnel and participants will be delivered via the app. Phone calls and\u002For Zoom sessions will be offered as an alternative if necessary. Our goal is to create a safe, effective means of delivering personalized exercise programming to rural adults that reduces barriers to exercise, improves physical fitness and biomarkers associated with dementia risk and lends itself to exercise adherence in a population that is at an increased risk for cognitive decline. Middle aged adults will be included in the study as they are at an age when successful behavior change is more probable (than older, institutionalized adults); older adults will be included as they are in the high-risk category for dementia. Following the exercise intervention, all baseline assessments will be repeated. Data will be compared to determine the impact of the exercise program on each variable (i.e. dementia risk biomarkers, QOL, physical fitness, etc.).",[61],"Sedentary Behavior","RECRUITING","2025-02-17",{"date":65,"type":38},"2025-02-18",{"date":67,"type":38},"2024-10-31",{"date":69,"type":20},"2025-07-01",{"name":44,"class":45},1,""]