[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Endo Health GmbH\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":67},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100644349","evaluation-of-a-mobile-menopause-application-100644349",false,"NCT07663305","Evaluation of a Mobile Menopause Application","EMMA","Inclusion Criteria:\n\n* Legal capacity\n* Ability to provide informed consent\n* Residency in Germany\n* Female gender\n* Age ≥18 years\n* Medically confirmed menopausal or other perimenopausal disorder (N95.1)\n* Ownership of a smartphone and ability to use it\n* Internet access for app usage and questionnaire completion\n* Email address for registration\n* Willingness to complete questionnaires online\n* Motivation for regular app usage\n* Sufficient proficiency in the German language\n* MRS II ≥ 9\n* Absence of exclusion criteria\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding during the study period\n* Current hormonal replacement therapy (HRT), initiation of HRT within eight weeks prior to study start and\u002For planned start of HRT during the study period\n* Changes in treatment with psychotropic medication within eight weeks prior to study start and\u002For planned during the study period\n* Start of psychotherapy within eight weeks prior to study start and\u002For planned during the study period\n* Start of a rehabilitation program within eight weeks prior to study start and\u002For planned during the study period\n* Surgery performed within eight weeks prior to study start and\u002For planned during the study period\n* Previous or current access to the Endo-App or other comparable digital health applications, or current active prescription\n* Current participation in other clinical studies\n* Failure to meet the inclusion criteria","FEMALE","18 Years",{"count":19,"type":20},426,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study examines whether a digital app can help women manage symptoms of menopause. A total of 426 women with medically confirmed menopausal symptoms are randomly assigned to either use the app in addition to their usual medical care for 24 weeks, or to continue with usual care alone. The app provides evidence-based content and exercises for multimodal menopause management. Participants are followed up over 24 weeks, with the primary outcome assessed at 12 weeks. The main goal is to evaluate whether the app improves menopause-specific quality of life.",[26],"N95.1 Menopausal and Female Climacteric States",[28,29,30],"Menopause","Digital Therapeutics","Quality of Life","NOT_YET_RECRUITING","2026-06-17",{"date":34,"type":35},"2026-06-23","ACTUAL",{"date":37,"type":20},"2026-06",{"date":39,"type":20},"2027-06",{"name":41,"class":42},"Endo Health GmbH","INDUSTRY",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":64,"leadSponsor":66,"locationsCount":43},"100586224","app-impact-on-quality-of-life-and-symptoms-in-pcos-100586224","NCT06912594","App Impact on Quality of Life and Symptoms in PCOS","Pilot Study to Investigate the Influence of an App on the Quality of Life and Symptoms of Patients With Polycystic Ovary Syndrome","Inclusion Criteria:\n\n* Legal capacity\n* Resident in Germany\n* Female gender\n* Age ≥18 years up to 65 years\n* Diagnosed and medically confirmed Polycystic Ovary Syndrome (E28.2)\n* Ownership of a smartphone with a compatible iOS or Android version and the ability to operate it\n* Internet access and an email address for registration, app usage, and completing questionnaires\n* Willingness to complete questionnaires online\n* Motivation to use the app regularly\n* Sufficient knowledge of the German language\n\nExclusion Criteria:\n\n* Changes in hormone therapy within eight weeks prior to the start of the study and\u002For planned within the next 12 weeks\n* Changes in treatment with metformin within eight weeks prior to the start of the study and\u002For planned within the next 12 weeks\n* Current treatment with medications for obesity (e.g., liraglutide, orlistat)\n* Changes in treatment with anti-androgens (e.g., spironolactone, cyproterone acetate, flutamide) within eight weeks prior to the start of the study and\u002For planned within the next 12 weeks\n* Pregnancy or breastfeeding\n* Current hormonal fertility treatment\n* Changes in treatment with psychotropic medications within eight weeks prior to the start of the study and\u002For planned within the next 12 weeks\n* Current psychotherapeutic treatment\n* Previous or current access to the Endo-App or other digital health applications (DiGAs)\n* Current participation in other clinical studies\n* Current nutritional counseling according to §20 SGB V or nutritional therapy according to §43 SGB V, or participation in weight reduction programs","65 Years",{"count":53,"type":20},220,[23],"This study investigates the influence of a PCOS app on the quality of life and symptoms of individuals with polycystic ovary syndrome (PCOS). The intervention group can use the app over the study period of twelve weeks in addition to care-as-usual (CAU). In the control group, this is compared with no use of the PCOS-App for a twelve-week period, that is, care-as-usual only\u002F continuation of the current treatment (waitlist design). The aim is to evaluate the effectiveness of the app and to gain insights for the design of future studies. The study is expected to last seven months and include 220 participants.",[57],"Polycystic Ovary Syndrome (PCOS)",[59,30,29],"PCOS","2025-04-02",{"date":62,"type":35},"2025-04-06",{"date":60,"type":20},{"date":65,"type":20},"2025-09",{"name":41,"class":42},""]