[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ente Ospedaliero Cantonale, Bellinzona\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":337},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,46,72,92,113,136,160,180,206,227,246,266,285,315],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100616237","real-time-monitoring-of-the-injection-pressure-during-the-peripheral-nerve-block-100616237",false,"NCT07302997","Real-Time Monitoring of the Injection Pressure During the Peripheral Nerve Block","A Single-Center, First-in-Human, Randomized, Controlled, Feasibility Study of a New Device for the Real-Time Continuous Monitoring of the Injection Pressure of Local Anesthetic in Subjects Undergoing Ultrasound-guided Peripheral Nerve Block: the Smart Needle Monitoring System Investigation","Smart Needle","Inclusion Criteria:\n\n* Informed Consent signed by the subject\n* Age ≥ 18 years\n* Scheduled for elective surgery below the elbow (e.g., hand surgery, distal radius surgery, forearm surgery) requiring an axillary block\n* ASA physical status I-III\n* Ability to understand the investigation\n* Ability and willingness to follow and complete the procedures of the investigation\n\nExclusion Criteria:\n\n* Contraindications to the axillary block (e.g., local infection)\n* Refusal of locoregional anesthesia for the surgical procedure\n* Pre-existing neurologic deficits in the operative extremity\n* Body Mass Index ≥ 35 kg\u002Fm2\n* Known allergy to local anesthetic (mepicavaine hydrochloride)\n* Inability to comply with post-operative evaluations e.g. due to language problems, psychological disorders, dementia, etc. of the subject","ALL","18 Years",{"count":20,"type":21},34,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial with medical device is to learn if the Smart Needle Monitoring System works to maintain a safe low injection pressure during a type of regional anaesthetic (Peripheral Nerve Block (PNB)) in patients due to undergo surgery below the elbow . It will also learn about the safety of the device and patients' perception of the quality of anesthesia.\n\nParticipants will:\n\n* be operated locally according to standard clinical practice\n* undergo post-anesthesia recovery and any neurologic symptoms or signs assessment on postoperative days 1 and 7",[27,28],"No Condition","Real-time Monitoring of the Injection Pressure During Ultrasound-guided Axillary Block",[30,31,32],"axillary block","injection pressure","real-time monitoring","RECRUITING","2026-03-12",{"date":36,"type":37},"2026-03-13","ACTUAL",{"date":39,"type":37},"2025-12-19",{"date":41,"type":21},"2026-12",{"name":43,"class":44},"Ente Ospedaliero Cantonale, Bellinzona","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":45},"100543392","quality-of-postoperative-analgesia-and-functional-recovery-after-elective-cesarean-delivery-100543392","NCT06355271","Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery","Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery Adding Different Doses of Intrathecal Fentanyl to Spinal Anesthesia With Bupivacaine and Intrathecal Morphine. A Single Center, Randomized, Multiple Blinded, Controlled Trial","MoFe","Inclusion Criteria:\n\n* patients over 18 year of age\n* height over 160 cm\n* American Society Anesthesiologists physical status I and II\n* term singleton parturients\n* scheduled for elective cesarean delivery during spinal anesthesia at Ospedale Regionale Bellinzona Valli\n\nExclusion Criteria:\n\n* patients with inability to consent\n* patient refusal\n* contraindication to spinal anesthesia (eg, hemodynamic instability, infection at the surgery site, and neurologic defects such as transverse myelitis)\n* emergency cesarean delivery\n* preeclampsia\u002Feclampsia\n* allergy to drugs used in the protocol","FEMALE",{"count":56,"type":21},63,[24],"Based on randomization, patients will receive a mixture for spinal anesthesia and will be followed in the following hours for the various outcomes and for functional recovery",[60],"Obstetric Pain",[62,63,64],"Cesarean section","Fentanyl","Functional Recovery",{"date":66,"type":37},"2026-03-16",{"date":68,"type":37},"2024-06-12",{"date":70,"type":21},"2027-12-31",{"name":43,"class":44},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":45},"100555058","ai-assisted-migraine-education-efficacy-safety-and-patients-acceptance-100555058","NCT06507150","AI-assisted Migraine Education: Efficacy, Safety and Patients' Acceptance","Inclusion Criteria:\n\n* aged between 18 and 65 years at the time of signing the informed consent\n* Newly diagnosis of migraine, confirmed through the medical chart\n* The participant must be capable of giving signed informed consent\n* Access to a laptop, computer, smartphone, or tablet\n\nExclusion Criteria:\n\n* Insufficient knowledge of the protocol language (italian)\n* Patients with cognitive impairment and\u002For unable to use or access the AI-powered learning platform developed in this study.\n* Vulnerable participants (e.g. minors, participants incapable of judgment or participants under tutelage)","65 Years",{"count":80,"type":21},140,[24],"Migraine affects 1 in 7 people globally, significantly impacting quality of life and economic productivity. Despite its prevalence, limited awareness leads to misdiagnosis, inadequate treatment, and stigmatization. AI can enhance migraine management through improved diagnosis, prediction, and personalized education. The primary objective of this study is to determine if adding AI-assisted migraine education to standard education improves patients' understanding of their condition more effectively.",[84],"Migraine","2026-03-11",{"date":34,"type":37},{"date":88,"type":37},"2024-09-01",{"date":90,"type":21},"2027-06",{"name":43,"class":44},{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":22,"phases":101,"briefSummary":102,"conditions":103,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":45},"100628301","this-is-a-study-to-find-out-whether-music-therapy-can-reduce-stress-during-wound-care-100628301","NCT07459855","This is a Study to Find Out Whether Music Therapy Can Reduce Stress During Wound Care","Music Therapy to Reduce Stress and Increase Satisfaction in Patients Undergoing Surgical Wound Dressings in the In-hospital Setting: a Randomized Study","Inclusion Criteria:\n\n* Hospitalized patients undergoing wound dressing procedures\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* Pregnant or lactating women\n* Cognitive impairment or language barriers\n* Severe hearing impairment\n* Clinical instability requiring urgent medical intervention at the time of wound dressing",{"count":100,"type":21},50,[24],"This study involves hospitalized patients who need wound dressing procedures. Patients will be assigned by chance to one of two groups. One group will listen to music of their choice during wound care, while the other group will receive standard wound care without music. The investigators will then compare the two groups to see whether listening to music helps reduce stress and improve the experience during the procedure.",[104],"Wound Surgical","2026-03-03",{"date":107,"type":37},"2026-03-10",{"date":109,"type":21},"2026-02-11",{"date":111,"type":21},"2026-05-31",{"name":43,"class":44},{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":120,"maxAge":121,"enrollmentInfo":122,"targetDuration":4,"studyType":22,"phases":124,"briefSummary":126,"conditions":127,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":45},"100441056","phase-4-this-is-a-study-to-verify-if-periarticular-hip-injection-of-corticosteroid-after-hip-replacement-reduce-the-pain-and-the-hospitalisation-time-100441056","NCT05023369","This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time","Periarticular Administration of Dexamethasone to Improve Post-operative Pain, Function, Nausea, Hospitalization Length, and Risk of Complications in Patients Undergoing Hip Arthroplasty - A Randomized Trial","Inclusion Criteria:\n\n* Patients undergoing unilateral cemented hip endoprosthesis for femoral neck fracture\n* Patients aged 50-90 years old\n* Patients with a BMI \\>18.5 and \\\u003C35\n* Patients able to provide informed consent and follow all the study procedures as indicated by the protocol\n* Informed Consent as documented by signature\n\nExclusion Criteria:\n\n* Contraindications to steroids\n* Revision endoprosthesis\n* Active steroid or immunosuppressive therapy in the last 30 days before the operation\n* Pregnant or breast-feeding women\n* Presence of other clinically significant concomitant disease states (ASA IV)\n* Uncontrolled diabetes mellitus\n* Contraindications to NSAIDs\n* Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus, SLE), gout, rheumatic arthritis\n* Known or suspected non-compliance, drug or alcohol abuse\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.\n* Participation in another study with investigational drug within the 30 days preceding and during the present study\n* Previous enrolment into the current study\n* Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons.","50 Years","90 Years",{"count":123,"type":21},110,[125],"PHASE4","The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of hospitalisation, use of analgesics drugs.",[128],"Femoral Neck Fractures",{"date":130,"type":37},"2026-03-05",{"date":132,"type":37},"2021-12-10",{"date":134,"type":21},"2026-11-01",{"name":43,"class":44},{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":45},"100627578","effect-of-virtual-reality-on-the-need-of-premedication-before-surgery-100627578","NCT07450456","Effect of Virtual Reality on the Need of Premedication Before Surgery","Effect of Virtual Reality Immersion on the Need of Pharmacological Premedication Before Cardiac Surgery","Inclusion Criteria:\n\n* All patients undergoing elective surgery\n* Minimal age of 18-year-old\n* Able to give informed consent for the study\n* Requesting pharmacological premedication in the pre-operative period.\n\nExclusion Criteria:\n\n* Lacking capacity or ability to complete the consent form or to respond to the required obligations linked to the study protocol\n* Contraindications to pharmacological premedication\n* Known cognitive dysfunction, previous history of neurological\u002Fpsychiatric diseases like epilepsy\n* Non Italian speaking patients\n* Injuries to the head\u002Fface that would prohibit wearing headsets\n* Infectious skin conditions of the head\u002Fface\n* Contact isolation due to bacteria and viruses\n* Symptoms of vertigo or motion sickness\n* Reduced visual or auditory acuity\n* Pregnancy\n* Claustrophobia",{"count":144,"type":21},40,[24],"This study will assess, on patients requesting a pharmacological premedication in the preoperative period, if virtual reality reality could reduce the request of pharmacological premedication while maintaining a good level of comfort for the patient. The aim of this study is to understand if virtual reality could reduce the need for pharmacological premedication and their associated secondary effects.",[148,149,150,151],"Anxiety","Premedication","Surgery","Virtual Reality","2026-02-27",{"date":154,"type":37},"2026-03-04",{"date":156,"type":37},"2025-11-11",{"date":158,"type":21},"2026-10",{"name":43,"class":44},{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":4,"eligibilityCriteria":166,"healthyVolunteers":11,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":167,"targetDuration":4,"studyType":22,"phases":169,"briefSummary":170,"conditions":171,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":177,"leadSponsor":179,"locationsCount":45},"100623750","this-is-a-study-to-find-out-whether-surgery-using-a-metal-plate-to-fix-a-broken-elbow-in-older-adults-leads-to-better-recovery-and-arm-function-compared-to-non-surgical-treatment-100623750","NCT07400692","This is a Study to Find Out Whether Surgery Using a Metal Plate to Fix a Broken Elbow in Older Adults Leads to Better Recovery and Arm Function Compared to Non-surgical Treatment","Treatment of Olecranon Fractures in the Elderly, a Randomised Controlled Trial Comparing Surgical and Conservative Treatment","Inclusion Criteria\n\n* Patients with an acute (\\\u003C 2 weeks) Mayo type 2A or 2B olecranon fracture\n* Patients aged \\> 65 years • Patients with reduced functional demand, with a score \\> 2 and \\\u003C 7 on the Clinical Frailty Scale\n* Patients able to provide informed consent and follow all study procedures as indicated in the protocol\n* Signed informed consent for study participation\n\nExclusion criteria:\n\n* Patients aged \\\u003C 65 years or with a Clinical Frailty Scale score \\> 7 or \\\u003C 2\n* Patients with a Mayo type 2A or 2B fracture seen more than 2 weeks after injury\n* Old fracture (\\> 6 months), pseudoarthrosis, or unhealed nerve injury of the ipsilateral upper limb\n* Open (Gustilo-Anderson type 2 or 3) or pathological fracture\n* Previous injury to, or other condition of, the elbow with severe functional impairment\n* Patients with severe comorbidities preventing safe surgical treatment\n* Other acute fracture or nerve damage of the ipsilateral upper limb\n* Known drug or alcohol abuse\n* Inability to follow study procedures (e.g., due to language barriers or severe comorbidities)",{"count":168,"type":21},84,[24],"This study takes place in one hospital and uses a random method to divide patients into groups. It looks at the best way to treat a broken elbow (specifically, a displaced olecranon fracture) in older adults who don't use their arms heavily. There are 84 patients in total, with 42 people in each group",[172],"Olecranon Fracture","2026-02-03",{"date":175,"type":37},"2026-02-10",{"date":173,"type":21},{"date":178,"type":21},"2030-02-03",{"name":43,"class":44},{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":187,"enrollmentInfo":188,"targetDuration":4,"studyType":22,"phases":190,"briefSummary":191,"conditions":192,"keywords":194,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":45},"100395447","a-study-to-compare-two-different-managements-after-ankle-surgery-immediate-and-delayed-weight-bearing-100395447","NCT04429217","A Study to Compare Two Different Managements After Ankle Surgery: Immediate and Delayed Weight-bearing.","Immediate vs Delayed Weight-bearing After Surgical Treatment of Malleolar Fractures: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Male and female adults\n* Age ranging from 18 to 70 years, included\n* Signed Informed Consent\n* Ankle fracture requiring surgical management classified as:1- Weber A fracture pattern (AO 44.A1, 44.A2, 44.A3) with or without association with a medial or posterior lesion\u002Ffracture or 2- Weber B fracture pattern (AO 44.B1, 44.B2, 44.B3) with or without association with a medial or posterior lesion\u002Ffracture\n* Willingness and ability to participate in the trial\n\nExclusion Criteria:\n\n* Weber C fracture pattern\n* Bilateral fractures or fractures in other locations\n* Maissoneauve associated lesion\n* Body Mass Index \\\u003C 18.5 and ≥ 30\n* Metabolic diseases influencing fracture healing processes\n* Medical comorbidities precluding operative intervention\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, general physical problem of the participant, etc.\n* Inability or contraindications to undergo the investigated intervention\n* Other clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular disease, etc.)\n* Pregnant women","70 Years",{"count":189,"type":21},100,[24],"The investigators will compare two types of rehabilitation in patients who undergo a surgery for treatment of malleolar fractures: immediate complete weight-bearing and delayed weight-bearing.\n\nThe investigators want to evaluate if the immediate complete weight-bearing can improve and hasten the functional outcome of the ankle without increasing the risk of complications.",[193],"Lateral Malleolus Fracture",[195,196,197],"Ankle","surgical treatment","malleolar fractures","2025-08-06",{"date":200,"type":37},"2025-08-07",{"date":202,"type":37},"2020-04-28",{"date":204,"type":21},"2028-02-02",{"name":43,"class":44},{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":212,"eligibilityCriteria":213,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":187,"enrollmentInfo":214,"targetDuration":4,"studyType":22,"phases":216,"briefSummary":217,"conditions":218,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":45},"100545784","this-is-a-study-to-evaluate-a-pre-confectioned-plantar-insole-for-the-treatment-of-plantar-heel-pain-100545784","NCT06386406","This is a Study to Evaluate a Pre-confectioned Plantar Insole for the Treatment of Plantar Heel Pain","A Mono-centric Clinical Investigation to Evaluate Performance of a Pre-confectioned Plantar Insole for the Treatment of Plantar Heel Pain.","TAP","Inclusion Criteria:\n\nMale and female adults\n\n* Age ranging 18 to 70 years\n* Patients with a history of at least 6 months of plantar fasciitis resistant to other conventional therapies\n* Willingness and ability to participate in the trial\n* Informed Consent signed by the subject\n\nExclusion Criteria:\n\n* Diabetes mellitus not controlled pharmacologically\n* Rheumatoid arthritis\n* Previous foot surgery\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, general physical problem of the participant, etc.",{"count":215,"type":21},25,[24],"Patients affected by plantar heel pain will be asked to use a pre-confectioned plantar insole for one year.\n\nThe aim of the study is to assess if the insole under study allows the patient to reach a better mobility and a faster return to the normal everyday life.",[219],"Plantar Fascitis","2025-08-05",{"date":198,"type":37},{"date":223,"type":37},"2024-04-23",{"date":225,"type":21},"2026-03-31",{"name":43,"class":44},{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":234,"targetDuration":4,"studyType":236,"phases":4,"briefSummary":237,"conditions":238,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":240,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":244,"locationsCount":245},"100537851","comparing-reports-recorded-by-the-patients-at-the-time-at-which-they-feels-pain-to-what-patients-report-at-monthly-visits-to-assess-symptoms-of-musculoskeletal-diseases-100537851","NCT06283199","Comparing Reports Recorded by the Patients at the Time at Which They Feels Pain to What Patients Report at Monthly Visits to Assess Symptoms of Musculoskeletal Diseases.","The Importance of Ecological Momentary Assessment to Capture the Whole Patient's Symptoms Experience in Musculo-skeletal Conditions","Inclusion Criteria:\n\n* Symptomatic patients\n* Patients able to give informed consent and to follow the protocol of the study (i.e. able to use a smartphone)\n* Patients \\>18 years\n* BMI \\\u003C35 and \\>18.5\n* Patients with a smartphone with Android or iOS as operative systems\n\nExclusion Criteria:\n\n* Patients unable to follow the protocol of the study (i.e. unable to use a smartphone, not owning a smartphone or unwilling to download or use the application)\n* Patients with a diagnosis of a musculoskeletal injury but without symptoms\n* Patients without a radiological examination confirming the diagnosis of musculoskeletal disease\n* Patients with planned surgery in the following 60 days\n* Pregnant or lactating woman\n* Patients with other diseases causing pain in the involved joint (e.g. rheumatoid arthritis or other rheumatologic diseases).\n* Surgical treatment in the last year and intra-articular injection in the last 6 months",{"count":235,"type":21},1500,"OBSERVATIONAL","Patients will be introduced to the use of a mobile application for their smartphone to record the Ecological Momentary Assessment (EMA). This app will ask the patients to assess their pain and function two times daily for 2 months.\n\nAfter 1 month and at the end of the 2 months, follow-up visits will be performed and patients will be asked to retrospectively evaluate the pain that they suffered and the level of function they had during the last month.",[239],"Musculoskeletal Pain",{"date":198,"type":37},{"date":242,"type":37},"2021-04-06",{"date":70,"type":21},{"name":43,"class":44},2,{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":251,"acronym":4,"eligibilityCriteria":252,"healthyVolunteers":11,"sex":17,"minAge":253,"maxAge":120,"enrollmentInfo":254,"targetDuration":4,"studyType":22,"phases":256,"briefSummary":257,"conditions":258,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":260,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":45},"100489979","this-is-a-study-to-evaluate-nanofractures-technique-in-the-treatment-of-cartilage-lesions-100489979","NCT05660161","This is a Study to Evaluate Nanofractures Technique in the Treatment of Cartilage Lesions","A Pilot Study to Evaluate the Functional Outcome of Nanofractures for the Treatment of Cartilage Lesions","Inclusion Criteria:\n\n* Patients with cartilage lesions of the knee scheduled for surgery\n* Age 16-50\n* BMI between 18.5 and 30 points\n* Ability to give informed consent\n\nExclusion Criteria:\n\n* Uncorrected knee instability\n* Meniscectomy \\> 50%\n* Uncorrected knee misalignment\n* Uncontrolled metabolic diseases\n* Inability to give informed consent","16 Years",{"count":255,"type":21},20,[24],"Articular cartilage lesions, with their inherent limited healing potential, remain a challenging problem for orthopaedic surgeons. Various techniques, both palliative and reparative, have been used to treat this injury with variable success rates. If not adequately treated, they may even lead to the development of early-onset osteoarthritis. Among all the available techniques, microfractures are used in restoring the cartilage tissue, especially in the deep and extended lesions.\n\nMore recently, the need for minor bone trauma with still adequate bleeding resulted in the development of nanofractures. Nanofracturing means creating perforations with a smaller diameter that go deeper into the bone while damaging it less. This is supposed to reduce the injury to the subchondral bone and increase the amount of bone marrow-derived mesenchymal stromal cells at the bone surface.\n\nThus, the aim of this pilot study is to evaluate the efficacy of nanofractures for the treatment of cartilage lesions of the knee, specifically focusing on the chondral healing that will be addressed with magnetic resonance imaging.",[259],"Cartilage Damage",{"date":198,"type":37},{"date":262,"type":37},"2023-03-02",{"date":264,"type":21},"2027-01",{"name":43,"class":44},{"id":267,"slug":268,"hasResults":11,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":121,"enrollmentInfo":273,"targetDuration":4,"studyType":22,"phases":274,"briefSummary":275,"conditions":276,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":278,"startDateStruct":280,"completionDateStruct":282,"leadSponsor":284,"locationsCount":45},"100489482","total-hip-arthroplasty-fluoroscopy-vs-freehand-100489482","NCT05653687","Total Hip Arthroplasty: Fluoroscopy vs Freehand","A Randomized, Monocentric Investigator-initiated Clinical Investigation Comparing Fluoroscopy Versus Freehand in Total Hip Arthroplasty","Inclusion Criteria:\n\n* Patients undergoing unilateral primary THA through DAA\n* Patients aged 18-90 years old.\n* Patients with a BMI \\>18 and \\\u003C35.\n* Patients able to provide informed consent.\n* Informed consent as documented by signature.\n\nExclusion Criteria:\n\n* Revision THA.\n* Women who are pregnant or breast feeding.\n* Presence of other clinically significant concomitant disease states (ASA IV).\n* Previous enrolment into the current study.\n* Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons.",{"count":168,"type":21},[24],"The aim of the study is to compare total hip arthroplasty intervention executed with or without the use of intraoperative fluoroscopy in terms of positioning of the hip prosthesis. The comparison will be made on post-operative follow-up X-ray performed as per clinical practice, in order to verify if intraoperative fluoroscopy provides better prosthesis components positioning or not.",[277],"Intraoperative Fluoroscopy",{"date":279,"type":37},"2025-08-08",{"date":281,"type":37},"2023-05-22",{"date":283,"type":21},"2026-03",{"name":43,"class":44},{"id":286,"slug":287,"hasResults":11,"nctId":288,"briefTitle":289,"officialTitle":290,"acronym":4,"eligibilityCriteria":291,"healthyVolunteers":292,"sex":17,"minAge":18,"maxAge":293,"enrollmentInfo":294,"targetDuration":4,"studyType":22,"phases":296,"briefSummary":297,"conditions":298,"keywords":301,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":309,"startDateStruct":310,"completionDateStruct":312,"leadSponsor":314,"locationsCount":45},"100480341","a-study-to-compare-early-and-partial-weight-bearing-after-hallux-valgus-surgery-100480341","NCT05534724","A Study to Compare Early and Partial Weight-bearing After Hallux Valgus Surgery","Is Full Weight Bearing After the Modified Lapidus Operation Possible? A Randomized Controlled Trial to Compare Early and Partial Weight-bearing","Inclusion Criteria:\n\n* Patient who undergo modified Lapidus arthrodesis operation and associated with:\n* Additional surgical gestures such as e.g. interventions on the proximal phalanx of the first finger (Akin) or interventions on the 2nd and \u002F or 3rd ray (Weil \u002F Hohmann) \\[23,24\\].\n* Willingness and ability to participate in the trial\n* Signed Informed Consent\n\nExclusion Criteria:\n\n* Diabetes mellitus\n* Rheumatoid arthritis\n* Previous foot surgery\n* Classic Lapidus surgery\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, general physical problem of the participant, etc.\n* Inability or contraindications to undergo the investigated intervention\n* Pregnant women",true,"85 Years",{"count":295,"type":21},122,[24],"This is a two-arm randomized controlled trial with the aim to evaluate the effectiveness and safety of post-operative management after a modified Lapidus arthrodesis with\u002Fwithout an Akin or a Weil\u002FHohmann surgery fusion with immediate complete weight-bearing compared with partial weight-bearing (10 - 15kg) for 6 weeks as a novel approach for rehabilitation after a foot surgery.",[299,300],"Hallux Valgus","Orthopedic Disorder",[302,303,304,305,306,307,308],"Quality of life","Bone consolidation","Foot surgery","Lapidus surgery","Weil surgery","Hohmann surgery","Akin surgery",{"date":198,"type":37},{"date":311,"type":37},"2023-01-19",{"date":313,"type":21},"2026-07-01",{"name":43,"class":44},{"id":316,"slug":317,"hasResults":11,"nctId":318,"briefTitle":319,"officialTitle":320,"acronym":4,"eligibilityCriteria":321,"healthyVolunteers":11,"sex":17,"minAge":322,"maxAge":323,"enrollmentInfo":324,"targetDuration":4,"studyType":236,"phases":4,"briefSummary":326,"conditions":327,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":330,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":336,"locationsCount":245},"100402053","ultrasound-evaluation-of-superior-mesenteric-artery-measurements-in-a-healthy-pediatric-population-100402053","NCT04515251","Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population","A Prospective, Observational, Multicenter Study on Ultrasound Evaluation of Superior Mesenteric Artery Measurements in a Healthy Pediatric Population","Inclusion Criteria:\n\n* Male and female children\n* Age ranging from10 to 15 years, included\n* Abdominal ultrasound examination to be performed for indications other than gastrointestinal evaluation\n* Signed Informed Consent\n\nExclusion Criteria:\n\n* Presence of a disease that could distort the anatomy around the SMA (e.g., abdominal mass, lymphadenopathy, severe scoliosis, free abdominal fluid)\n* Oncologic patients at risk of neoplastic cachexia.","10 Years","15 Years",{"count":325,"type":21},289,"Multicenter, prospective, observational research project on children aged from 10 to 15 years old undergoing abdominal ultrasound examinations during routine clinical practice.",[328],"Superior Mesenteric Artery Syndrome","2025-07-30",{"date":331,"type":37},"2025-07-31",{"date":333,"type":37},"2020-04-27",{"date":335,"type":21},"2026-12-30",{"name":43,"class":44},""]