[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Eodyne Systems SL\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":81},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":5},"100584143","personalised-health-motor-and-cognitive-assistance-system-for-rehabilitation-phrase-100584143",false,"NCT06885502","Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE)","Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE): A Randomized Clinical Trial","PHRASE-2024","Inclusion Criteria:\n\n* Patients presenting an ischemic or intracerebral haemorrhagic stroke, ≥ 3 months post-stroke.\n* Age \\> 18 years old\n* Moderate to mild proximal upper limb motor impairment Medical Research Council Scale (MRC \\>2).\n* ARAT: \\\u003C50, inclusive, to avoid ceiling effects while allowing room for improvement.\n* Able to sit on a chair or a wheelchair to interact with the RGS system.\n* Minimal experience with smartphone technology based on the clinician's opinion\n* Willing to participate and agree to comply with the trial scheme and procedures\n* Must sign an Informed Consent Form (ICF) indicating that they understand the purpose and the procedures of the study.\n\nExclusion Criteria:\n\n* Presence of a condition or abnormality that, in the opinion of the investigator, would compromise the safety of the patient or the quality of the data.\n* Severe cognitive capabilities that prevent the execution of the study, evaluated by the MoCA \\\u003C 19 or based on the clinician's opinion.\n* Pre-stroke history of upper limb motor disability.\n* Unable to use the RGS independently, according to the clinician's observations, and needing more support from a caregiver to use the RGS.","ALL","18 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is a multicentric randomized controlled trial evaluating the effectiveness of digital technology, specifically a smartphone with integrated VR-and AR-based intervention, for at-home rehabilitation after stroke. The study focuses on combined motor and cognitive training for patients in the late subacute and chronic phases post-stroke. The intervention is provided through the Rehabilitation Gaming System application RGSapp, a goal-oriented, first-person virtual reality (VR) and augmented reality (AR) mobile application for upper limb rehabilitation. A total of seventy participants will be randomly assigned (1:1 ratio) to either the RGSapp intervention or conventional therapy\u002Fstandard of care for six weeks. The primary outcome is motor function improvement (upper limb), assessed using the Action Research Arm Test (ARAT). Secondary outcomes include changes in cognitive function, depression, usability, adherence, validity of remote assessments, and healthcare costs.",[27,28,29,30],"Stroke","Stroke Rehabilitation","Chronic Stroke Patients","Post Stroke Recovery",[27,32,33,34,35,36,37,38,39,40,41],"ARAT","Motor rehabilitation","Stroke rehabilitation","Telemedicine","Virtual Reality (VR)","Augmented Reality (AR)","Cognitive rehabilitation","Rehabilitation at home","eHealth technology","upper limbs","RECRUITING","2025-12-31",{"date":45,"type":46},"2026-01-06","ACTUAL",{"date":48,"type":46},"2025-02-21",{"date":50,"type":21},"2026-06-30",{"name":52,"class":53},"Eodyne Systems SL","INDUSTRY",{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":67,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100603590","integrating-ai-in-stroke-neurorehabilitation-100603590","NCT07138495","Integrating AI in Stroke Neurorehabilitation","Integrating AI in Stroke Neurorehabilitation (AISN)","AISN","Inclusion Criteria\n\n* ≥ 6 months post-stroke\n* Patients presenting a first-ever ischemic or intracerebral hemorrhagic stroke\n* Mild to Moderate unilateral upper limb motor impairment: Medical Research Council proximal and distal upper limb MRC ≥2; Action Research Arm Test: ARAT score \\\u003C 50 (0 = no function, 57 = no functional limitation).\n* Age \\> 18 years old\n* Able to sit on a chair or a wheelchair and interact with RGS during an entire session\n* Minimal experience with smartphone technology based on the clinician's opinion\n* Willing to participate in the RGS therapy\n* Sign the Informed Consent Form\n\nExclusion Criteria\n\n* Diagnosis with Epilepsy\n* Severe cognitive capabilities preventing the execution of the experiment or according to clinicians' criteria.\n* Severe associated impairment such as proximal but not distal spasticity, communication disabilities (sensory, Wernicke aphasia or apraxia), major pain (VAS \\> 75-100 mm), orthopedic devices that would interfere with the correct execution of the experiment (Modified Ashworth Scale \\> 3)\n* Unable to use the RGS app independently according to the clinician's observations and lacking support from a caregiver to use the RGS app\n* No experience with smartphone technology or based on the clinician's opinion.\n* Refusal to sign the Informed Consent\n* Participating or planning to participate in another trial while being part of the present study.",{"count":63,"type":21},192,[24],"The AISN multicenter randomized controlled trial will assess the effectiveness of a novel artificial intelligence (AI)-based clinical decision-support system integrated into the Rehabilitation Gaming System (RGS) for home-based post-stroke rehabilitation. Approximately 192 participants ≥6 months post-stroke will be recruited across several European centers and assigned to one of three groups: RGS with AI decision support, RGS without AI, or standard care. The primary outcome is upper limb motor improvement for stroke patients, with secondary measures including cognitive function, independence, quality of life, usability, cost-effectiveness, and AI-based support performance.",[27],[27,68,69,70,71],"home based rehabilitation","digital health","virtual reality","personalized rehabilitation","2025-12-16",{"date":74,"type":46},"2025-12-22",{"date":76,"type":46},"2025-10-15",{"date":78,"type":21},"2026-12-30",{"name":52,"class":53},4,""]