[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Erbil Polytechnic University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100635327","knee-osteoarthritis-rehab-high-intensity-laser-vs-classical-modalities-100635327",false,"NCT07551245","Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities","Rehabilitation of Knee Osteoarthritis by High Intensity Laser Therapy vs Classical Modalities","HILT-CM (KOA)","Inclusion Criteria:\n\n* Diagnosis of Knee Osteoarthritis: Patients must have a clinical and radiographic diagnosis of knee OA according to the American College of Rheumatology (ACR) criteria, including evidence of joint space narrowing, osteophyte formation, and other degenerative changes observed on X-rays or MRI.\n\nAge: Adults aged between 40 and 75 years. Willingness to Participate: Participants must provide informed consent and be willing to adhere to the study protocol, including attending all treatment sessions and follow-up assessments.\n\nKellgren-Lawrence Grade: Patients with knee OA grades 1-3 (mild to moderate OA).\n\nExclusion Criteria:\n\n* Contraindications to Laser Therapy:\n\nActive malignancy History of epilepsy Photosensitivity disorders Active infection in the treatment area\n\nSurgical History:\n\nPatients who have undergone knee surgery within the past 6 months Scheduled surgery during the study period\n\nAdvanced Disease:\n\nKellgren-Lawrence Grade 4 (severe OA) where surgical intervention is indicated\n\nPregnancy or Lactation:\n\nPregnant or lactating women\n\nSevere Comorbidities:\n\nUncontrolled diabetes Severe cardiovascular disease Neurological disorders that might interfere with participation or affect treatment outcomes",true,"ALL","30 Years","60 Years",{"count":22,"type":23},100,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis. Knee osteoarthritis is a common condition, especially in older adults, causing pain, stiffness, reduced movement, and difficulty performing daily activities. Current treatments focus on reducing pain and improving joint function.\n\nIn this study, 100 patients with knee osteoarthritis will be divided into two groups. One group will receive HILT combined with therapeutic exercises, while the other group will receive conventional physical therapy modalities along with the same exercises. The treatment outcomes will be evaluated over time.\n\nThe main outcomes include pain reduction (measured by pain scales such as WOMAC and VAS), improvement in joint function, and structural changes in the knee assessed by MRI. In addition, laboratory tests will be used to measure inflammation, cartilage health markers, and oxidative stress before and after treatment.\n\nThe goal is to determine whether HILT provides better pain relief, improves joint function, and is safe compared to standard therapy. The results may help improve rehabilitation strategies for patients with knee osteoarthritis.",[29],"Knee Arthritis Osteoarthritis",[31,32,33],"LASER","knee OA","classical modalities","RECRUITING","2026-04-19",{"date":37,"type":38},"2026-04-24","ACTUAL",{"date":40,"type":38},"2026-04-20",{"date":42,"type":23},"2027-01-20",{"name":44,"class":45},"Erbil Polytechnic University","OTHER",""]