[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Escola Superior de Tecnologia da Saúde do Porto\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":239},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,48,74,99,122,151,173,193,217],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100644476","effect-of-the-suboccipital-inhibition-technique-on-balance-changes-100644476",false,"NCT07670819","Effect of the Suboccipital Inhibition Technique on Balance Changes","Inclusion Criteria:\n\n* Healthy individuals (defined by the absence of the exclusion criteria listed below)\n* Aged between 18 and 35 years\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Recent history of falls\n* History of spinal or foot surgery\n* Cervical fractures\n* Known postural instability\n* Suspected neurovascular compromise\n* Neurological deficits\n* Neurological or vestibular disorders\n* Use of medication or substances that may affect the nervous system\n* Osteopathy students from the 2nd, 3rd, and 4th academic years",true,"ALL","18 Years","35 Years",{"count":20,"type":21},74,"ESTIMATED","INTERVENTIONAL",[24],"NA","Postural balance is an essential capacity for functional autonomy and the performance of activities of daily living, relying on the continuous integration of visual, vestibular, and somatosensory information. Within this system, the upper cervical region plays a particularly important role, as it contributes to the orientation of the head in space and to the coordination between the head, eyes, and trunk. Due to their deep location between the occiput, atlas, and axis, the suboccipital muscles have a high proprioceptive significance and are frequently associated with cervical position control and sensorimotor regulation.\n\nChanges in muscle tension, stiffness, or dysfunction in this region may alter the quality of afferent information transmitted to the central nervous system, potentially interfering with postural stability, head position awareness, body sway, and center of pressure control. In this context, the suboccipital inhibition technique is used in osteopathic practice as a manual intervention aimed at reducing myofascial tension, promoting relaxation of the upper cervical musculature, and potentially normalizing proprioceptive input.",[27],"Balance Changes",[27,29,30,31,32,33,34,35],"Osteophaty","Balance","Suboccipital muscles","Suboccipital inhibition","Cervical proprioception","Postural control","Center of pressure","NOT_YET_RECRUITING","2026-06-25",{"date":39,"type":40},"2026-06-29","ACTUAL",{"date":42,"type":21},"2026-07",{"date":44,"type":21},"2026-09",{"name":46,"class":47},"Escola Superior de Tecnologia da Saúde do Porto","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":68,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":72,"locationsCount":73},"100644595","effect-of-osteopathic-technique-on-maximum-mouth-opening-width-masseter-muscle-tone-and-stiffness-100644595","NCT07670832","Effect of Osteopathic Technique on Maximum Mouth Opening Width, Masseter Muscle Tone and Stiffness","Effect of Temporomandibular Joint Compression and Decompression Technique on Maximum Mouth Opening Width, Masseter Muscle Tone and Stiffness: A Randomized Controlled Study","Inclusion Criteria:\n\n* Asymptomatic adults that signed the informed consent\n* Functional dentition\n* Preserved masticatory function\n\nExclusion Criteria:\n\n* Diagnosis of inflammatory systemic disorders\n* Diagnosis of cardiovascular disorders\n* Diagnosis of respiratory disorders\n* Diagnosis of central nervous system disorders\n* Diagnosis of rheumatic disorders\n* Visual disturbance affecting balance or proprioception",{"count":56,"type":21},32,[24],"The purpose of this study is to assess the effect of compression and decompression thecnique on the temporomandibular joint on maximum mouth opening width, masseter muscle tone and stiffness in asymptomatic adults, compared with a control condition consisting of cranial listening touch without therapeutic intent. Evaluations will be conducted immediately after the intervention and one week later.",[60],"Asymptomatic Condition",[62,63,64,65,66,67],"Masseter","Maximum Mouth opening Width","muscle tone","TMJ","Temporomandibular joint","stiffness",{"date":39,"type":40},{"date":70,"type":21},"2026-06",{"date":44,"type":21},{"name":46,"class":47},1,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":95,"startDateStruct":96,"completionDateStruct":97,"leadSponsor":98,"locationsCount":73},"100644565","effects-of-an-osteopathic-manual-therapy-protocol-on-heart-rate-variability-stress-and-anxiety-in-young-adults-100644565","NCT07670806","Effects of an Osteopathic Manual Therapy Protocol on Heart Rate Variability, Stress, and Anxiety in Young Adults","Effect of an Osteopathic Intervention Protocol on the Parasympathetic System on Stress and Anxiety in Young Adults: a Randomized Clinical Trial","Inclusion Criteria:\n\n* age between 18 and 35 years old;\n* presence of symptoms\u002Fdiagnosis of stress and\u002For anxiety in the last week.\n\nExclusion Criteria:\n\n* individuals with cognitive impairments that prevent participation;\n* individuals with cardiovascular problems;\n* pregnant women;\n* those taking medications that affect cardiac function, anxiolytics, and antidepressants;\n* caffeine consumption in the last 4 hours;\n* alcohol consumption in the previous 24 hours;\n* tobacco use in the last 48 hours;\n* recent cervical trauma;\n* students of osteopathy.","30 Years",{"count":83,"type":21},30,[24],"Anxiety is characterized by excessive worry and anticipation of future threats, often accompanied by physiological and behavioral manifestations. Anxiety disorders are among the most prevalent mental health conditions worldwide and represent a significant public health concern, particularly among young adults and university students, who frequently experience academic, social, and financial stressors. The aim of this randomized clinical trial is to evaluate the effect of a protocol, consisting of 4 manual techniques, compared to a placebo group, in heart rate variability immediately after the intervention and in anxiety after one week in young adults. The main questions it aims to answer are:\n\nDoes the osteopathic intervention protocol influence the parasympathetic nervous system? Does the osteopathic intervention protocol influence anxiety and stress?\n\nThe researchers will compare the osteopathic protocol to a placebo (simulation technique), in order to see if the protocol influences anxiety and stress. Participants will:\n\nPrior to the intervention, complete the EADS questionnaire and undergo measurement of heart rate variability; Undergo the protocol or placebo; Immediately after the intervention, they will undergo the measurement of heart rate variability; After one week in the intervention, complete the questionnaire EADS.",[87,88],"Stress","Anxiety",[88,90,91,92,93,94],"Autonomic System Nervous","Parasympathetic Autonomic System Nervous","heart rate variability","Manual Therapy Techniques","Young Adults",{"date":39,"type":40},{"date":70,"type":21},{"date":44,"type":21},{"name":46,"class":47},{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":107,"briefSummary":108,"conditions":109,"keywords":112,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":120,"leadSponsor":121,"locationsCount":73},"100644588","psoas-major-muscle-intervention-on-chronic-lumbar-pain-in-cleaning-professionals-100644588","NCT07672197","Psoas Major Muscle Intervention on Chronic Lumbar Pain in Cleaning Professionals.","Influence of the Stretching Technique on the Psoas Major Muscle on Chronic Lumbar Pain in Cleaning Professionals: Randomized Controlled Trial.","Inclusion Criteria:\n\n* Being a cleaning professional for at least 4 years\n* Report at least 1 episode of lumbar pain in the last 3 months\n\nExclusion Criteria:\n\n* Any severe spinal condition (such as spondylolisthesis, spine fracture, etc.)\n* Any severe neurological or rheumatological condition\n* Pregnancy\n* Daily use of pain medication",{"count":83,"type":21},[24],"The goal of this randomized controlled trial is to determine the effect of a psoas major muscle intervention on non-specific and chronic lumbar pain in cleaning professionals. It is expected that this intervention will reduce the severity and frequency of symptoms. This study aims to evaluate the effect of psoas major stretching techniques. To collect data, participants will rate their pain intensity on a numeric pain scale at rest and during maximal lumbar flexion. Secondary variables include lumbar flexion range of motion (ROM), assessed by the Schöber test, and hip ROM, which will be measured before and after the intervention using a digital goniometer.",[110,111],"Lumbar Pain","Non-specific Low Back Pain (NSLBP)",[113,114,115,116],"manual therapy","cleaning professionals","psoas major","stretching technique",{"date":118,"type":40},"2026-06-26",{"date":42,"type":21},{"date":44,"type":21},{"name":46,"class":47},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":15,"sex":129,"minAge":17,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":133,"briefSummary":134,"conditions":135,"keywords":137,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":147,"completionDateStruct":148,"leadSponsor":150,"locationsCount":73},"100552604","influence-of-osteopathic-intervention-on-cervical-muscles-in-tension-headaches-in-women-100552604","NCT06475248","Influence of Osteopathic Intervention on Cervical Muscles in Tension Headaches in Women","Influence of Osteopathic Intervention on Cervical Muscles in Tension Headaches in Women: Randomized Controlled Trial","Inclusion Criteria:\n\n* Tension headaches;\n* Being over eighteen years of age;\n\nExclusion Criteria:\n\n* Loss of mobility of cervical;\n* Cervical and shoulder pain during episodes;\n* Other headaches (migraine, cervicogenic headache...)\n* Other interventions and\u002For pharmacological treatment a few days before the intervention;\n* Epilepsy;\n* Trauma.","FEMALE","60 Years",{"count":132,"type":21},43,[24],"This study aims to understand whether there is any relationship between the intervention on the trapezius, sternocleidomastoid and suboccipital muscles in patients with chronic tension headaches.",[136],"Tension Headaches",[138,139,140,141,142,143,144],"Tension headaches","Trapezius Stretching","sternocleidomastoid Stretching","Suboccipital Inhibition","Manual Therapy","Osteopathy","HIT-6","2026-06-22",{"date":37,"type":40},{"date":44,"type":21},{"date":149,"type":21},"2026-12-11",{"name":46,"class":47},{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":156,"acronym":4,"eligibilityCriteria":157,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":158,"enrollmentInfo":159,"targetDuration":4,"studyType":22,"phases":161,"briefSummary":162,"conditions":163,"keywords":165,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":171,"leadSponsor":172,"locationsCount":4},"100634642","effect-of-osteopathic-intervention-on-migraine-100634642","NCT07542340","Effect of Osteopathic Intervention on Migraine","Effect of Osteopathic Intervention on Migraine: A Randomised Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 50 years.\n* Presented five or more migraine episodes according to the criteria established by Monteiro et al. (2009), namely headache episodes with a minimum duration of 4 hours, unilateral location, pulsating character, photophobia, phonophobia, nausea, and vomiting.\n\nExclusion Criteria:\n\n* recent traumas not investigated by complementary examinations, clinical history of cranio-cervical traumas, such as fracture, dislocation, and ligament rupture (Ricard \\& Sallé, 2010; Croibier, 2005);\n* tumours, meningitis, neuropraxia, disc herniation, or cervical hemivertebra (Ricard \\& Sallé, 2010; Croibier, 2005);\n* contagious disease, such as tuberculosis (Croibier, 2005);\n* cardiovascular diseases, such as severe arterial hypertension, venous thrombosis, myocardial infarction, angina pectoris, recent stroke, intracranial arterial aneurysm (Croibier, 2005);\n* advanced osteoporosis (Croibier, 2005);\n* radiotherapy\u002Fchemotherapy treatment currently active or within 6 months of the last session (Croibier, 2005);\n* anticoagulant medication, vitamin K, treatment with corticosteroids, analgesics, and NSAIDs 10 to 15 days per month (Bigal et al., 2008; Croibier, 2005; International Headache Society (IHS), 2018).","50 Years",{"count":160,"type":21},45,[24],"Migraine is a common, disabling neurological condition characterized by severe, often unilateral pain accompanied by sensory symptoms like nausea and photophobia. Its pathophysiology involves activation of the trigeminovascular system, neuro-inflammation, and nervous system sensitisation.\n\nDue to the convergence of trigeminal and cervical nerves in the upper neck (C2), manual therapy may influence migraine symptoms. Osteopathic techniques, such as suboccipital inhibition and C2 manipulation, aim to reduce pain intensity and frequency by normalising mobility and reducing nociceptive stimulation. While promising, further research is needed to validate these interventions through rigorous clinical trials.",[164],"Migraine",[141,164,166,143],"Osteopathic Manipulative Treatment","2026-04-28",{"date":169,"type":40},"2026-05-04",{"date":70,"type":21},{"date":44,"type":21},{"name":46,"class":47},{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":81,"enrollmentInfo":180,"targetDuration":4,"studyType":22,"phases":182,"briefSummary":183,"conditions":184,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":192,"locationsCount":4},"100592510","psoas-muscle-release-in-non-specific-mechanical-low-back-pain-100592510","NCT06994364","Psoas Muscle Release in Non-specific Mechanical Low Back Pain","Efficacy of Psoas Muscle Release in Young Adults With Non-specific Mechanical Low Back Pain: Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 30 years.\n* Presence of low back pain for less than 1 month.\n* Presence of a latent trigger point in the psoas muscle.\n\nExclusion Criteria:\n\n* Volunteers with low back pain caused by: Disc herniation, Tumor, Infection, Fracture, Osteoporosis, Structural deformity or Inflammation.\n* Individuals with a history of spinal surgery.\n* Continuous use of analgesics.\n* Participants who had undergone manual therapy in the previous month.\n* Pregnant individuals.\n* Obese individuals.\n* Students of Osteopathy (from the 2nd, 3rd, or 4th year) and professionals in the manual therapy field.\n* Participants presenting red flags for osteopathic intervention.\n* Individuals with cognitive impairments that hindered their ability to understand the study\u002Fproject.",{"count":181,"type":21},40,[24],"Nonspecific low back pain affects approximately 80% of the population at some point in their lives.\n\nThe psoas muscle-positioned between the lumbar and pelvic regions-together with the paravertebral muscles, constitutes the primary muscular group responsible for dynamic stabilization of the spine. Alterations in this muscle may contribute to the onset of low back pain by modifying spinal biomechanics, particularly through increased lumbar lordosis and greater mechanical overload in the lumbar region.\n\nLatent myofascial trigger points are asymptomatic but can lead to muscle shortening and weakness. They are characterized by local tenderness and may provoke a localized muscular response known as a local twitch response.\n\nThe aim of this randomized experimental study was to evaluate the immediate effect of ischemic compression applied to the trigger point of the psoas muscle on pain perception and lumbar range of motion.\n\nResearchers will compare a group with a placebo technique to see if the release of the psoas muscle produces effects in this condition.\n\nThe variables analyzed in this study included low back pain, assessed using the Numeric Pain Rating Scale (NPRS); lateral lumbar flexion (right and left), measured using a tape measure (distance from the third finger to the floor); and lumbar flexion range of motion, assessed using the Schober test.",[185],"Low Back Pain","2025-09-15",{"date":188,"type":40},"2025-09-16",{"date":190,"type":21},"2026-04",{"date":44,"type":21},{"name":46,"class":47},{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":81,"enrollmentInfo":200,"targetDuration":4,"studyType":22,"phases":201,"briefSummary":202,"conditions":203,"keywords":205,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":73},"100544909","effect-of-the-diaphragm-stretching-technique-on-nonspecific-low-back-pain-100544909","NCT06375018","Effect of the Diaphragm Stretching Technique on Nonspecific Low Back Pain","Effect of the Diaphragm Stretching Technique on Symptomatology in Young Adults With Nonspecific Low Back Pain: Randomized Controlled Trial","Inclusion Criteria:\n\n* Nonspecific low back pain;\n* Age between 18 and 30.\n\nExclusion Criteria:\n\n* Serious cardiovascular and cardiorespiratory causes;\n* Spinal pathologies and injuries to the lumbar spine;\n* Cancer patients;\n* Pacemaker or implant carriers;\n* Pregnant women or volunteers suspected of being pregnant.",{"count":160,"type":21},[24],"This study aims to analyze the efficacy of diaphragm stretching technique on symptomatology in young adults with nonspecific low back pain.",[204],"Nonspecific Low Back Pain",[206,185,143,207,208,94],"Diaphragm","Osteopathic Medicine","Stretching Technique","2024-09-02",{"date":211,"type":40},"2024-09-05",{"date":213,"type":21},"2024-12",{"date":215,"type":21},"2025-12",{"name":46,"class":47},{"id":218,"slug":219,"hasResults":11,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":224,"targetDuration":4,"studyType":22,"phases":226,"briefSummary":227,"conditions":228,"keywords":230,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":238,"locationsCount":73},"100549854","effectiveness-of-the-suboccipital-inhibition-technique-in-forward-head-posture-100549854","NCT06439472","Effectiveness of the Suboccipital Inhibition Technique in Forward Head Posture.","Effectiveness of the Suboccipital Inhibition Technique in Individuals With Forward Head Posture: Randomized Controlled Trial","Inclusion Criteria:\n\n* male and female;\n* be over 18 years old;\n* have a craniovertebral angle of less than 49.9º.\n\nExclusion Criteria:\n\n* have a craniovertebral angle greater than 49.9º;\n* be a 3rd or 4th year osteopathy student;\n* be an osteopath.",{"count":225,"type":21},50,[24],"In this randomized controlled experimental trial, it is aimed to verify the effectiveness of applying the suboccipital inhibition technique in altering forward head posture, increasing the craniovertebral angle and decreasing the angle between the chin, the external acoustic meatus and the sternal angle.",[229],"Individuals With Forward Head Posture",[231],"Forward head posture; Craniovertebral angle; Suboccipital muscles; Osteopathy.","2024-06-02",{"date":234,"type":40},"2024-06-04",{"date":236,"type":21},"2024-09",{"date":213,"type":21},{"name":46,"class":47},""]