[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Evergreen General Hospital, Taiwan\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":95},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100602742","computer-aided-water-exchange-colonoscopy-with-and-without-linked-color-imaging-for-detection-of-clinically-significant-serrated-lesions-100602742",false,"NCT07127471","Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions","A Multicenter Prospective Randomized Controlled Trial of Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions in Computer-Aided Water Exchange Colonoscopy","Inclusion Criteria:\n\n* Male and female patients aged 40-80 years scheduled for average-risk screening colonoscopy, post-polypectomy surveillance, diagnosis for gastrointestinal symptoms (including unexplained iron deficiency anemia and clinically significant diarrhea of unexplained origin), or referred for colonoscopy owing to a positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT) result.\n\nExclusion Criteria:\n\n* familial adenomatous polyposis and hereditary non-polyposis CRC syndrome\n* personal history of serrated polyposis syndrome\n* personal history of CRC\n* history of inflammatory bowel disease\n* previous colonic resection\n* overt gastrointestinal bleeding\n* emergency colonoscopy or inpatients\n* planned EMR or ESD of large polyps\n* colon stricture or obstruction\n* contraindications to colonoscopy (eg, acute diverticulitis or toxic megacolon)\n* antithrombotic therapy precluding complete polyp resection\n* American Society of Anesthesiology classification of physical status \\>3\n* pregnant women or women planning pregnancy\n* refusal to provide a written informed consent",true,"ALL","40 Years","80 Years",{"count":21,"type":22},1090,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to compare the detection rate of clinically significant serrated lesions (CSSL) in participants undergoing water exchange (WE) colonoscopy with artificial intelligence (AI)-based computer-aided detection (CADe) for screening, surveillance, diagnosis for symptoms, or referred owing to a positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT) result. There will be two arms in this study: WE with AI-assisted CADe (WEAID) control and WEAID plus linked-color imaging (LCI). The main question it aims to answer is whether the addition of LCI into WEAID colonoscopy increases CSSL detection rate. Both groups use water instead of air to insert the colonoscope into the cecum. The control method uses CADe to help detect colonic lesions. The study method uses a combination of CADe and LCI to detect lesions. Researchers will compare CSSL detection rate to see if the addition of LCI increases the detection of CSSL during CADe-assisted WE colonoscopy.",[28,29,30,31],"Sessile Colonic Polyp","Serrated Lesion","Sessile Serrated Lesion","Colon Adenomas","RECRUITING","2025-11-17",{"date":35,"type":36},"2025-11-20","ACTUAL",{"date":33,"type":36},{"date":39,"type":22},"2027-07-31",{"name":41,"class":42},"Evergreen General Hospital, Taiwan","OTHER",4,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":51,"maxAge":19,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},"100448936","can-overall-adenoma-detection-rate-replace-screening-adenoma-detection-rate--multicenter-study-100448936","NCT05125939","Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study","Improving Colonoscopy Adenoma Detection Metrics by Extending the Screening-only Measurement to All Indications: a Prospective Multicenter Study","Inclusion Criteria:\n\n* consecutive patients aged ≥50 years undergoing colonoscopy are eligible for enrollment.\n\nExclusion Criteria:\n\n* high risk family history of colorectal cancer (CRC) e.g., familial adenomatous polyposis, hereditary non-polyposis CRC syndrome, multiple first degree relatives with CRC, or a single first degree relative with CRC at \\\u003C60 years\n* serrated polyposis syndrome\n* inflammatory bowel disease\n* colonoscopy to remove a large neoplastic polyps\n* obstructive lesions of the colon\n* gastrointestinal bleeding\n* current participation in other studies\n* hospitalized patients\n* mental retardation\n* pregnancy\n* refusal to provide a written informed consent.","50 Years",{"count":53,"type":22},2700,"OBSERVATIONAL","This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR. Overall indication includes screening, surveillance, and diagnostic indications.",[57,58],"Adenoma Detection Rate","Colonoscopy",[58,60,61],"Adenoma detection rate","Screening","2025-08-04",{"date":64,"type":36},"2025-08-07",{"date":66,"type":36},"2021-11-20",{"date":68,"type":22},"2026-09-30",{"name":41,"class":42},6,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":16,"sex":17,"minAge":78,"maxAge":19,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":81,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":93,"locationsCount":94},"100554274","water-exchange-and-co2-insufflation-with-abdominal-compression-device-to-reduce-manual-assistance-100554274","NCT06496958","Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance","CO2 Insufflation Colonoscopy With an Abdominal Compression Device and Water Exchange Colonoscopy to Reduce Manual Assistance by Endoscopy Staff: A Multicenter Randomized Trial","Inclusion Criteria:\n\n* Patients aged 45-80 years having an average risk for colorectal cancer who plan to undergo sedated outpatient colonoscopy for screening, surveillance, and those who have received a positive fecal immunochemical test result\n\nExclusion Criteria:\n\n* Patients with hereditary colorectal cancer syndrome, including familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer (Lynch syndrome)\n* Patients with serrated polyposis syndrome\n* Patients with known or suspected inflammatory bowel disease\n* Patients with a history of colorectal cancer or other intra-abdominal malignancy\n* Patients with a history of colorectal resection\n* Patients with a history of abdominal aortic aneurysm, cirrhosis, ascites, or other severe comorbid illnesses\n* Patients with recent wounds or skin rash on the anterior abdominal wall and back\n* Patients with known ventral hernia\n* Patients with unsedated procedure\n* Patients with planned bidirectional endoscopy\n* Patients with body mass index \\>35 kg\u002Fm2\n* Patients with waist circumference \\\u003C55 cm or \\>105 cm\n* Patients with known or suspected gastroparesis\n* Patients with planned therapeutic procedures (e.g., hemostasis, removal of a large polyp)\n* Patients with mental retardation\n* Pregnant women or those planning pregnancy\n* Patients unwilling to participate in the study","45 Years",{"count":80,"type":22},400,[25],"The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower proportion of patients requiring manual abdominal pressure during colonoscopic insertion compared with CO2 insufflation alone.",[84,85,58,86],"Manual Pressure","Repositioning","Colon Polyp","2024-11-03",{"date":89,"type":36},"2024-11-05",{"date":91,"type":36},"2024-09-02",{"date":68,"type":22},{"name":41,"class":42},2,""]