[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fatih Sultan Mehmet Training and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":539},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,19,0,[8,45,82,107,135,170,195,222,249,273,299,320,352,379,414,441,465,490,516],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100642008","remifentanil-vs-esmolol-during-intubation-for-cerebral-aneurysm-coil-embolization-100642008",false,"NCT07660861","Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil Embolization","Effects of Remifentanil Versus Esmolol on Optic Nerve Sheath Diameter\u002FEyeball Transverse Diameter Ratio During Endotracheal Intubation in Patients Undergoing Cerebral Aneurysm Coil Embolization: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective cerebral aneurysm coil embolization under general anesthesia\n* Planned endotracheal intubation\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Emergency procedures\n* Hemodynamic instability before induction of anesthesia\n* Severe cardiac conduction abnormalities or clinically significant arrhythmias\n* Contraindication or allergy to remifentanil or esmolol\n* Chronic opioid use or opioid dependence\n* Known orbital disease, ocular trauma, or conditions interfering with optic nerve sheath diameter measurements\n* Anticipated difficult airway\n* Pregnancy\n* Refusal to participate in the study","ALL","18 Years",{"count":19,"type":20},84,"ESTIMATED","INTERVENTIONAL",[23],"NA","Endotracheal intubation may cause significant increases in blood pressure, heart rate, and intracranial pressure, particularly in patients undergoing cerebral aneurysm coil embolization. Remifentanil and esmolol are commonly used agents to attenuate these responses during anesthesia induction.\n\nThis randomized controlled trial aims to compare the effects of remifentanil and esmolol administered before endotracheal intubation on optic nerve sheath diameter\u002Feyeball transverse diameter ratio (ONSD\u002FETD), a noninvasive surrogate marker of intracranial pressure, as well as hemodynamic responses in patients undergoing elective cerebral aneurysm coil embolization.\n\nThe findings may help identify the most effective strategy for minimizing intubation-related intracranial pressure changes and hemodynamic fluctuations in neurointerventional anesthesia practice.",[26,27],"Cerebral Aneurysm Unruptured","Intracranial Pressure",[29,27,30,31,32],"Optic Nerve Sheath Diameter","Remifentanil","Esmolol","Coil Embolization","NOT_YET_RECRUITING","2026-06-16",{"date":36,"type":37},"2026-06-22","ACTUAL",{"date":36,"type":20},{"date":40,"type":20},"2027-07-01",{"name":42,"class":43},"Fatih Sultan Mehmet Training and Research Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":44},"100636200","eyelid-taping-alone-versus-taping-with-lubricant-eye-drops-for-perioperative-corneal-protection-100636200","NCT07562594","Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection","Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection During General Anesthesia: A Randomized Assessor-Blinded Trial With Cost-Effectiveness Analysis","Inclusion Criteria:\n\n* Age 18 to 75 years\n* ASA physical status I or II\n* Scheduled for elective non-ocular surgery under general anesthesia\n* Expected anesthesia duration between 30 and 180 minutes\n* Supine surgical position\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Preoperative corneal epithelial defect, keratitis, conjunctivitis, conjunctival hyperemia, or chemosis\n* Known ocular surface disease (dry eye syndrome, Sjögren syndrome, rheumatoid arthritis, systemic lupus erythematosus, or other systemic conditions associated with ocular surface involvement)\n* Use of topical or systemic medications known to affect tear production within the past 30 days\n* History of ocular surgery or ocular trauma\n* Contact lens use\n* Planned head and neck surgery\n* Prone or lateral decubitus surgical position\n* Patients requiring rapid sequence induction\n* Inability or refusal to provide written informed consent",true,"75 Years",{"count":55,"type":20},200,[23],"During general anesthesia, the eye's natural protective reflexes are suppressed, which can lead to corneal drying and injury. To prevent this, anesthesiologists routinely tape the eyelids closed. In many centers, lubricant eye drops are also applied in addition to taping, but whether this adds meaningful protection is unclear.This study will compare two approaches to eye protection during general anesthesia lasting 30 minutes to 3 hours: eyelid taping alone versus eyelid taping combined with lubricant eye drops. Two hundred adult patients undergoing elective, non-eye surgery in the supine position will be randomly assigned to one of the two groups.The main outcome is corneal surface damage measured by a standardized fluorescein staining score (NEI scale, 0-15) assessed by a blinded evaluator one hour after surgery. Secondary outcomes include tear film stability (TBUT), tear production (Schirmer test), patient-reported eye symptoms at 2 and 24 hours after surgery, and a cost-effectiveness analysis comparing the two approaches.If taping alone proves equally effective, routine use of lubricant eye drops may be unnecessary, reducing costs without compromising patient safety.",[59,60,61],"Corneal Injury","Exposure Keratopathy","Perioperative Complications",[63,64,65,66,67,68,69,70,71,72,73],"Corneal protection","General anesthesia","Eyelid taping","Lubricant eye drops","Corneal fluorescein staining","NEI corneal staining scale","Perioperative eye care","Schirmer test","Tear break-up time","Cost-effectiveness","Randomized controlled trial","2026-05-04",{"date":76,"type":37},"2026-05-07",{"date":78,"type":20},"2026-06-01",{"date":80,"type":20},"2026-12-02",{"name":42,"class":43},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":94,"phases":4,"briefSummary":95,"conditions":96,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":44},"100630389","the-efficacy-and-safety-of-a-single-dose-hyaluronic-acid-injection-in-the-treatment-of-knee-osteoarthritis-100630389","NCT07487038","The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis","Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in Adults With Symptomatic Knee Osteoarthritis: A Retrospective Study","ESSDHAITKO","Inclusion Criteria:\n\n* Participants who have provided written informed consent.\n* Male and female participants aged 40 to 70.\n* Bilateral or unilateral, painful, primary knee osteoarthritis.\n* Knee pain lasting at least 4 weeks while standing, walking, and\u002For moving, and the presence of at least one of the following features on an X-ray taken within the last 3 months: tibiofemoral osteophytes, femoral or tibial endplate osteosclerosis, or narrowing of the joint space (Kellgren-Lawrence grade 2-3).\n* Baseline Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Score (sum of five 100-mm components) between 200 and 400 mm.\n* Individuals deemed by the investigator to be able to adhere to the visit schedule.\n* Discontinuation of all NSAIDs, corticosteroids, and other pain relievers, including over-the-counter medications, herbal treatments, or chondroprotective agents prior to injection, and no use of these during the study follow-up period (except for acetaminophen).\n* Patients who have not received another intra-articular injection in the knee or participated in a physical therapy program during the follow-up period.\n\nExclusion Criteria:\n\n* Participants hospitalized in the hospital.\n* Participants with inflammatory knee conditions other than OA (e.g., rheumatoid arthritis, chronic hemochromatosis, sickle cell anemia, and\u002For chondrocalcinosis, as well as arthropathies associated with systemic diseases such as gout and hemophilia, and infectious joint disease).\n\nThe presence of significant joint effusion identified by the investigator during a clinical examination and confirmed by an ultrasound examination performed on each patient to determine the presence of effusion\n\n* Body mass index (BMI) \\>35 kg\u002Fm²\n* Severe misalignment of the knee axis (i.e., \\>12° severe varus or valgus deformity and\u002For clinically significant moderate to severe instability).\n* Clinical findings of hip osteoarthritis (OA) and\u002For hip joint replacement on the same side as the affected knee. Hip joint replacement on the opposite side of the affected knee is not exclusionary, provided the patient does not have symptomatic hip OA.\n* Surgical intervention on the symptomatic knee within the previous 12 months (including joint replacement) or arthroscopy of the symptomatic knee within the past 3 months (note: joint replacement of the contralateral knee is permitted if performed more than 12 months prior and the participant does not report pain of ≥ 20 mm on the WOMAC pain subscale).\n* Intra-articular (IA) injections in both knees within the past 4 weeks (e.g., corticosteroids, chondroprotective agents).\n* Changes to current medications or the addition of new medications to treat knee OA within the past 4 weeks (i.e., a change in dose or regimen lasting at least 4 weeks).\n* Regular use of opioid pain relievers for pain management. Use of long-acting pain relievers such as analgesic patches, methadone, and levorphanol at any time","40 Years","70 Years",{"count":93,"type":20},133,"OBSERVATIONAL","HA therapy typically consists of several intra-articular injections administered at weekly intervals. A single-dose IA-HA treatment offers patients and physicians a treatment option that involves both lower costs and fewer clinic visits. Furthermore, considering the administration procedure, we believe that single-dose therapy helps reduce the risk of potential side effects.\n\nIn light of this information, our study aims to retrospectively evaluate the efficacy and safety of HA in patients with symptomatic knee OA who have received a single-dose intra-articular HA injection.",[97,98],"Knee Osteoarthristis","Hyaluronic Acid","2026-04-24",{"date":101,"type":37},"2026-04-29",{"date":103,"type":20},"2026-05-01",{"date":105,"type":20},"2026-05-15",{"name":42,"class":43},{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":114,"targetDuration":116,"studyType":94,"phases":4,"briefSummary":117,"conditions":118,"keywords":120,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":44},"100634897","effects-of-ultrasound-guided-scalp-block-on-opioid-use-hemodynamics-and-postoperative-inflammation-in-craniotomy-100634897","NCT07545655","Effects of Ultrasound-Guided Scalp Block on Opioid Use, Hemodynamics, and Postoperative Inflammation in Craniotomy","Investigation of the Effects of Preoperative Ultrasound-Guided Scalp Block on Perioperative Opioid Consumption, Hemodynamic Stability, and Inflammatory Response in Patients Undergoing Craniotomy With a Skull Pin Head Holder","Inclusion Criteria:\n\n* Aged 18 years and older\n* Scheduled for elective intracranial surgery with skull pin head holder fixation\n* Classified as American Society of Anesthesiologists (ASA) physical status I-III\n* Provided written informed consent in the preoperative period\n\nExclusion Criteria:\n\n* Allergy to local anesthetics\n* Coagulopathy or anticoagulant use\n* Local infection at injection site\n* Pregnancy or breastfeeding\n* Chronic opioid use (\\>3 months) or chronic pain syndrome\n* Severe psychiatric disorders affecting pain assessment\n* Emergency surgery\n* Active infection or rheumatic disease\n* Hematological disease or malignancy (active or within 5 years)\n* Recent use of biological agents, chemotherapy, or corticosteroids (within 30 days)\n* NSAID use within 24 hours before surgery\n* Advanced organ failure (NYHA III-IV, Child-Pugh C, eGFR \\\u003C30 mL\u002Fmin)\n* Refusal to participate\n* Communication difficulties preventing pain assessment",{"count":115,"type":20},60,"1 Year","This study shows that in craniotomy patients using a skull pin head holder, an ultrasound-guided scalp block reduces perioperative opioid consumption, improves hemodynamic stability, and decreases the inflammatory response.",[119],"Craniotomy Surgery",[121,122,123,124,125,126],"Craniotomy","Ultrasound-guided scalp block","Skull pin head holder","Perioperative opioid consumption","Hemodynamic stability","Inflammatory response","2026-04-21",{"date":129,"type":37},"2026-04-22",{"date":131,"type":20},"2026-04-10",{"date":133,"type":20},"2027-03-10",{"name":42,"class":43},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":143,"targetDuration":4,"studyType":94,"phases":4,"briefSummary":145,"conditions":146,"keywords":151,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":167,"leadSponsor":169,"locationsCount":44},"100633591","ultrasound-vs-clinical-parameters-for-difficult-airway-prediction-in-obesity-100633591","NCT07528677","Ultrasound vs Clinical Parameters for Difficult Airway Prediction in Obesity","Comparison of Airway Ultrasonography and Conventional Difficult Airway Parameters for Predicting Difficult Airway in Obese Patients: A Prospective Observational Study","Inclusion Criteria:\n\n* Age 18-65 years\n* BMI \\>30 kg\u002Fm2\n* ASA physical status I, II, or III\n* Scheduled for elective surgery requiring orotracheal intubation under general anesthesia\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Emergency surgery\n* History of previous head and neck surgery or radiotherapy\n* Known or anticipated difficult airway (history of difficult intubation)\n* Presence of cervical spine pathology or limited neck mobility\n* Presence of oropharyngeal or laryngeal pathology\n* Pregnancy\n* Patients with tracheostomy\n* Refusal to participate","65 Years",{"count":144,"type":20},70,"Obesity is associated with anatomical changes in the upper airway that increase the risk of difficult laryngoscopy and difficult mask ventilation during anesthesia. Conventional airway assessment parameters such as Mallampati score, neck circumference, and STOP-BANG scale are widely used but have limited predictive accuracy in obese patients. Airway ultrasonography has emerged as a promising non-invasive tool for difficult airway prediction; however, ultrasonographic criteria have not yet been standardized.\n\nThis prospective observational study aims to evaluate the utility of airway ultrasonography in predicting difficult airway in adult obese patients (BMI \\>30 kg\u002Fm²) scheduled for elective surgery under general anesthesia. Ultrasonographic measurements will include the distance from skin to hyoid bone (DSHB) at the level of the hyoid bone, the anterior neck soft tissue thickness at the thyrohyoid membrane level, and the hyomental distance ratio (HMDR). These parameters will be compared with conventional airway assessment tools and correlated with intraoperative Cormack-Lehane laryngoscopy grade and Han Scale mask ventilation score to determine their predictive value for difficult airway.",[147,148,149,150],"Obesity (BMI > 35)","Difficult Airway","Difficult Airway Intubation","Difficult Mask Ventilation",[152,153,154,155,156,157,158,159,160,161,64,162],"Airway ultrasonography","Difficult airway prediction","Obese patients","Cormack-Lehane classification","Han Scale","Hyomental distance ratio","Distance from skin to hyoid bone","Neck circumference","Mallampati score","STOP-BANG scale","Orotracheal intubation","2026-04-09",{"date":165,"type":37},"2026-04-14",{"date":131,"type":20},{"date":168,"type":20},"2026-11",{"name":42,"class":43},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":177,"targetDuration":116,"studyType":94,"phases":4,"briefSummary":179,"conditions":180,"keywords":182,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":44},"100633218","laryngeal-edema-assessment-by-cuff-leak-test-and-ultrasound-in-icu-patients-and-its-relationship-with-weaning-success-100633218","NCT07523828","Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success","The Relationship Between Assessment of Laryngeal Edema in Intensive Care Patients Using Cuff Leak Test and Ultrasound-Guided Laryngeal Air Column Width Difference and Weaning Success","Inclusion Criteria:\n\n* Patients who have been intubated and receiving invasive mechanical ventilation for at least 24 hours in the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital and who are considered by the intensive care physician to be ready for weaning from mechanical ventilation:\n* Patients over 18 years of age\n* Patients who have given their voluntary consent\n\nExclusion Criteria:\n\n* Patients under 18 years of age\n* Patients with a history of oral cavity surgery such as direct laryngoscopy and biopsy, microlaryngoscopic surgery, tonsillectomy, adenoidectomy, soft palate, oropharynx, hypopharynx, larynx and trachea,\n* Patients with a history of allergy, asthma, reflux, upper respiratory tract viral or fungal infections, and cancer surgery,\n* Patients who received radiotherapy to the neck region, or who had more than one intubation attempt in the previous year,\n* Tracheostomized patients, patients with upper respiratory tract obstruction, vocal cord paralysis, and patients with stridor clinical picture before intubation,\n* Patients for whom voluntary consent cannot be obtained",{"count":178,"type":20},100,"This study evaluates laryngeal edema in ICU patients during weaning from mechanical ventilation. It compares the cuff leak test and ultrasound-based laryngeal air column measurements in predicting weaning success. Ultrasound offers a non-invasive and real-time alternative for airway assessment. The study also examines post-extubation complications such as stridor, sore throat, dysphonia, and dysphagia.",[181],"Laryngeal Edema",[183,184,185,186],"laryngeal edema","airway ultrasound","cuff leak test","weaning success","2026-04-05",{"date":189,"type":37},"2026-04-13",{"date":191,"type":20},"2026-04-08",{"date":193,"type":20},"2026-08-30",{"name":42,"class":43},{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":201,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":203,"targetDuration":205,"studyType":94,"phases":4,"briefSummary":206,"conditions":207,"keywords":210,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":44},"100630268","lymphoedema-diagnosis-and-treatment-100630268","NCT07485465","Lymphoedema Diagnosis and Treatment","The Role of Chat GPT in the Diagnosis and Treatment of Lymphedema","CDTL","Inclusion Criteria:\n\n* Patients over the age of 18\n* Clinical diagnosis of lymphoedema\n* Clinical diagnosis of lipoedema\n* Clinical diagnosis of venous insufficiency\n\nExclusion Criteria:\n\n* Lack of medical history\n* Lack of demographic data\n* Lack of clinical data and\n* Lack of imaging methods",{"count":204,"type":20},25,"1 Day","A domain-specific, custom-trained large language model for the differential diagnosis and treatment planning of lymphedema, lipedema, and venous insufficiency.",[208,209],"Lymphedema","Artificial Intelligence (AI)",[211,212,213],"lymphedema","chat gpt","artificial intelligence","2026-03-17",{"date":216,"type":37},"2026-03-20",{"date":218,"type":20},"2026-03-15",{"date":220,"type":20},"2026-04-01",{"name":42,"class":43},{"id":223,"slug":224,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":228,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":230,"targetDuration":4,"studyType":21,"phases":232,"briefSummary":233,"conditions":234,"keywords":237,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":44},"100627158","effect-of-magnetotherapy-combined-with-cold-application-and-exercise-in-patients-with-lateral-epicondylitis-100627158","NCT07444996","Effect of Magnetotherapy Combined With Cold Application and Exercise in Patients With Lateral Epicondylitis","Effectiveness of Magnetotherapy in Patients With Lateral Epicondylitis: A Randomized Double-Blind Controlled Trial","MAGNET-LE","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Clinical diagnosis of lateral epicondylitis\n* Tenderness over the lateral epicondyle on palpation\n* Tenderness over the common extensor tendon\n* At least one positive provocation test (Cozen, Mill's, or Maudsley's test)\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Acute infection\n* Elbow surgery within the past 12 months\n* Presence of electronic implants (e.g., pacemaker, cochlear implant)\n* Pregnancy\n* Physical therapy for the elbow within the past 3 months\n* Corticosteroid injection to the elbow within the past 3 months\n* History of elbow trauma within the past 3 months\n* Hyperthyroidism or adrenal hyperfunction\n* Paroxysmal neurological disorders (e.g., epilepsy)\n* Myasthenia gravis\n* Inability to comply with the treatment protocol or follow-up assessments",{"count":231,"type":20},40,[23],"This study aims to evaluate the effectiveness of magnetotherapy in the treatment of lateral epicondylitis (tennis elbow). Lateral epicondylitis is a common musculoskeletal condition characterized by pain and tenderness over the outer part of the elbow, often associated with repetitive wrist extension and gripping activities. It may cause reduced grip strength, functional limitations, and decreased quality of life.\n\nIn this prospective, randomized, double-blind, sham-controlled clinical trial, 40 patients aged 18-65 years diagnosed with lateral epicondylitis will be enrolled. Participants will be randomly assigned into two groups using the sealed envelope method.\n\nThe experimental group will receive active magnetotherapy in addition to standard treatment (local application and supervised exercise therapy). The control group will receive sham magnetotherapy (inactive device without magnetic field) plus the same standard treatment. Treatments will be administered five days per week for three weeks.\n\nMagnetotherapy will be applied at a frequency of 50 Hz and intensity of 85 Gauss for 30 minutes per session. All participants will also receive 15 minutes of local application and 15 minutes of supervised exercises including eccentric wrist extensor exercises, isotonic strengthening, stretching, and isometric exercises.\n\nOutcomes will be evaluated at baseline (week 0), at the end of treatment (week 3), and at follow-up (week 12). Primary and secondary outcome measures include pain intensity (Visual Analog Scale), pressure pain threshold (algometer), grip strength (hand dynamometer), functional status (PRTEE and QuickDASH questionnaires), quality of life (SF-36), clinical provocation tests (Cozen, Mill's, and Maudsley's tests), and patient satisfaction (Likert scale).\n\nThe study hypothesis is that adding magnetotherapy to standard treatment will provide additional benefit in reducing pain and improving function compared to standard treatment alone.",[235,236],"Magnetotherapy","Lateral Epicondylitis (Tennis Elbow)",[238,239,240],"magnetotherapy","lateral epicondylitis","tennis elbow","2026-03-05",{"date":243,"type":37},"2026-03-09",{"date":245,"type":20},"2026-02-27",{"date":247,"type":20},"2026-11-27",{"name":42,"class":43},{"id":250,"slug":251,"hasResults":11,"nctId":252,"briefTitle":253,"officialTitle":254,"acronym":4,"eligibilityCriteria":255,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":256,"targetDuration":4,"studyType":94,"phases":4,"briefSummary":257,"conditions":258,"keywords":261,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":4},"100627691","prediction-of-postoperative-pain-using-venous-cannulation-pain-and-preoperative-anxiety-scores-100627691","NCT07451925","Prediction of Postoperative Pain Using Venous Cannulation Pain and Preoperative Anxiety Scores","Association of Venous Cannulation Pain and Preoperative Anxiety (APAIS) With Postoperative Pain Following Elective Laparoscopic Cholecystectomy: A Prospective Observational Study","Inclusion Criteria:\n\n* Age ≥18 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia\n* Ability to understand and use the Visual Analog Scale (VAS)\n* Ability to complete the Amsterdam Preoperative Anxiety and Information Scale (APAIS)\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency surgery\n* Conversion from laparoscopic to open surgery\n* Cognitive impairment or inability to communicate effectively\n* Chronic pain lasting longer than 3 months\n* More than three venous cannulation attempts\n* Surgical duration exceeding 2 hours\n* Refusal to participate",{"count":178,"type":20},"Postoperative pain remains a significant clinical problem affecting recovery, mobilization, and patient satisfaction after surgery. Considerable interindividual variability exists in postoperative pain intensity even among patients undergoing the same surgical procedure. This variability may be influenced not only by the extent of surgical trauma but also by individual pain sensitivity and psychological factors such as preoperative anxiety.\n\nThe aim of this prospective observational study is to evaluate whether pain intensity reported during routine venous cannulation and preoperative anxiety levels assessed by the Amsterdam Preoperative Anxiety and Information Scale (APAIS) can predict early postoperative pain severity in patients undergoing elective laparoscopic cholecystectomy under general anesthesia. Venous cannulation pain will be assessed using a 0-10 visual analog scale (VAS), and anxiety levels will be measured preoperatively using APAIS. Postoperative pain will be evaluated at predefined time points within the first 12 hours after surgery using VAS scores and analgesic consumption. Identifying simple and easily obtainable preoperative predictors may allow individualized postoperative analgesic strategies for patients at higher risk of severe postoperative pain.",[259,260],"Preoperative Anxiety","Postoperative Pain",[262,263,264,265],"APAIS","postoperative pain","preoperative anxiety","Laparoscopic Cholecystectomy","2026-03-04",{"date":241,"type":37},{"date":269,"type":20},"2026-03-02",{"date":271,"type":20},"2026-07-01",{"name":42,"class":43},{"id":274,"slug":275,"hasResults":11,"nctId":276,"briefTitle":277,"officialTitle":278,"acronym":4,"eligibilityCriteria":279,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":280,"enrollmentInfo":281,"targetDuration":4,"studyType":21,"phases":283,"briefSummary":284,"conditions":285,"keywords":288,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":44},"100625857","effect-of-kinesio-taping-combined-with-schroth-therapy-in-young-adults-with-idiopathic-scoliosis-100625857","NCT07428083","Effect of Kinesio Taping Combined With Schroth Therapy in Young Adults With Idiopathic Scoliosis","Comparison of Schroth Therapy and Kinesiotaping in Lower Back and Back Pain in Young Adults With Idiopathic Scoliosis: A Double-Blind Placebo-Controlled Randomized Study","Inclusion Criteria:\n\n* Individuals aged between 18 and 30 years.\n* Radiologically confirmed diagnosis of idiopathic scoliosis.\n* Cobb angle between 10° and 30° and considered candidates for conservative treatment.\n* Risser stage 5.\n* History of low back or back pain within the last 3 months (defined as NRS ≥ 4).\n* No acute orthopedic or neurological condition that would prevent participation in physical exercise interventions.\n* Willingness to participate voluntarily and provide written informed consent.\n* Ability to attend treatment sessions regularly throughout the study period.\n\nExclusion Criteria:\n\n* Diagnosis of non-structural (functional) scoliosis, congenital scoliosis, or neuromuscular scoliosis.\n* History of previous spinal surgery.\n* Participation in scoliosis-specific exercise therapy within the last 6 months.\n* Presence of open wounds, dermatological conditions, or allergy to taping materials.\n* History of psychiatric disorders or neurological diseases.","30 Years",{"count":282,"type":20},51,[23],"In this study, the effects of Kinesio Taping methods applied in combination with Schroth therapy on pain and functional capacity in young adults diagnosed with idiopathic scoliosis will be evaluated.\n\nThis study is designed as a randomized controlled trial. Participants will be randomly assigned to one of three groups:\n\nGroup 1: Schroth therapy combined with Kinesio Taping\n\nGroup 2: Schroth therapy alone\n\nGroup 3: Schroth therapy combined with sham Kinesio Taping\n\nKinesio Taping will be applied for 4 weeks. The tape will remain in place for 5 consecutive days, followed by a 2-day rest period for the skin, and this cycle will be repeated throughout the intervention period.\n\nSchroth therapy will be administered 3 times per week for 4 weeks.\n\nAssessments will be conducted at baseline (Week 0), during treatment (Week 2), at the end of treatment (Week 4), and at follow-up (Week 8).\n\nThe primary outcome measures will be pain intensity assessed by the Numeric Rating Scale (NRS) and functional disability assessed by the Oswestry Disability Index (ODI). Secondary outcome measures will include the Scoliosis Research Society-22 (SRS-22) questionnaire and the Patient Global Impression of Change (PGIC) scale.",[286,287],"Scoliosis Idiopathic","Kinesio Taping",[289,290,291],"Scoliosis idiopathic","Kinesio taping","Schroth therapy","2026-02-26",{"date":269,"type":37},{"date":295,"type":20},"2026-02-01",{"date":297,"type":20},"2026-11-01",{"name":42,"class":43},{"id":300,"slug":301,"hasResults":11,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":4,"eligibilityCriteria":305,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":306,"targetDuration":4,"studyType":21,"phases":307,"briefSummary":308,"conditions":309,"keywords":312,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":315,"lastUpdatePostDateStruct":316,"startDateStruct":317,"completionDateStruct":318,"leadSponsor":319,"locationsCount":44},"100626463","magnetotherapy-in-carpal-tunnel-syndrome-randomized-controlled-study-100626463","NCT07435961","Magnetotherapy in Carpal Tunnel Syndrome: Randomized Controlled Study","Evaluation of the Effectiveness of Magnetotherapy in Patients With Carpal Tunnel Syndrome: A Placebo-Controlled, Triple-Arm, Randomized, Double-Blind Study","Inclusion Criteria:\n\n* Adults aged between 18 and 65 years.\n\nClinical diagnosis of carpal tunnel syndrome (CTS) based on physical examination findings, including positive Tinel and\u002For Phalen tests and hypoesthesia in the 3rd to 5th digits.\n\nElectrophysiologically confirmed mild-to-moderate carpal tunnel syndrome based on electromyography (EMG) findings.\n\nExclusion Criteria:\n\n* Severe carpal tunnel syndrome confirmed electrophysiologically by electromyography (EMG).\n\nHistory of previous surgical intervention for carpal tunnel syndrome.\n\nPresence of other peripheral nerve entrapments (e.g., ulnar nerve entrapment, radial nerve entrapment).\n\nElectrophysiologically confirmed polyneuropathy or cervical radiculopathy\u002Fcervical discopathy.\n\nRheumatologic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus).\n\nDiabetes mellitus (Type 1 or Type 2).\n\nPregnancy.\n\nPresence of electronic implants such as cardiac pacemaker, cochlear implant, or implantable defibrillator.\n\nActive acute infection.\n\nHistory of malignancy.\n\nReceipt of physical therapy or rehabilitation for the wrist or surrounding area within the past 6 months.\n\nCorticosteroid injection to the wrist within the past 6 months.\n\nHyperthyroidism or adrenal gland hyperfunction.\n\nOpen growth plates (epiphyseal plates not closed).\n\nParoxysmal neurological disorders (e.g., epilepsy).\n\nMyasthenia gravis.\n\nRegular use of pain medications such as pregabalin, duloxetine, or non-steroidal anti-inflammatory drugs (NSAIDs).",{"count":115,"type":20},[23],"This study is designed to investigate the effectiveness of low-frequency pulsed electromagnetic field therapy in individuals diagnosed with mild-to-moderate carpal tunnel syndrome (CTS). This double-blind, randomized controlled trial will randomly assign participants into three groups:\n\nGroup 1: Active magnetotherapy\n\nGroup 2: Placebo magnetotherapy (treatment using an identical device that does not generate a magnetic field)\n\nGroup 3: Routine (conservative) treatment group\n\nAll participants will receive a standard nighttime wrist splint and a standardized nerve and tendon gliding exercise protocol. Magnetic field applications will be administered five days per week for a total of 15 sessions. Assessments will be conducted at baseline (T0), at the end of treatment (T1 - Week 3), at 1 month (T2), and at 3 months (T3).\n\nThe primary outcome measures include the Boston Carpal Tunnel Questionnaire (BCTQ), pain intensity assessed by the Visual Analog Scale (VAS), functional status measured by QuickDASH, median nerve cross-sectional area assessed by ultrasonography, sensory function evaluated using the Semmes-Weinstein monofilament test, grip strength measured by dynamometry, and clinical test results (Tinel and Phalen tests). Secondary outcomes include sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI) and patient satisfaction.\n\nThis study aims to contribute to the scientific evidence regarding the effectiveness of magnetotherapy as a non-invasive treatment option for carpal tunnel syndrome.",[235,310,311],"Carpal Tunnel Syndrome (CTS)","Median Nerve Compression",[313,314,238],"median nerve compression","carpal tunnel syndrome(cts)","2026-02-21",{"date":245,"type":37},{"date":295,"type":20},{"date":297,"type":20},{"name":42,"class":43},{"id":321,"slug":322,"hasResults":11,"nctId":323,"briefTitle":324,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":326,"enrollmentInfo":327,"targetDuration":4,"studyType":94,"phases":4,"briefSummary":328,"conditions":329,"keywords":335,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":344,"lastUpdatePostDateStruct":345,"startDateStruct":347,"completionDateStruct":349,"leadSponsor":351,"locationsCount":44},"100625957","validity-and-reliability-of-the-hypertonia-assessment-tool-hat-in-stroke-patients-100625957","NCT07429383","Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke Patients","Inclusion Criteria:\n\n* Age 18 years and older\n* Clinically and radiologically confirmed diagnosis of stroke (ischemic or -hemorrhagic)\n* Brunnstrom stage between 2 and 6\n* Presence of post-stroke hypertonia (spasticity, dystonia, or rigidity)\n* Cognitive level sufficient to cooperate with assessments (Mini-Mental State Examination (MMSE) score \\>23 or equivalent clinical evaluation)\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Age under 18 years\n* Presence of severe accompanying neurodegenerative diseases (e.g., Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis)\n* Presence of primary musculoskeletal disorders affecting motor performance (e.g., rheumatologic diseases, fractures)\n* Brunnstrom stage of 1\n* Severe aphasia, impaired consciousness, or cognitive deficits preventing effective communication and cooperation\n* Any psychiatric disorder that may interfere with study participation","80 Years",{"count":115,"type":20},"In this study, the validity and reliability of the Hypertonia Assessment Tool (HAT), which has previously been validated in the pediatric cerebral palsy (CP) population, will be evaluated in adult individuals who have experienced a stroke. The HAT is a specific clinical instrument designed to differentiate subtypes of hypertonia, including spasticity, dystonia, and rigidity.\n\nAccurate classification of hypertonia subtypes following stroke is crucial for guiding rehabilitation strategies. However, the HAT has not yet been validated in the adult post-stroke population. This study will be conducted at the Physical Medicine and Rehabilitation Clinic of SBU Fatih Sultan Mehmet Training and Research Hospital. The study aims to evaluate the validity and reliability of the HAT for use in adults with stroke.",[330,331,332,333,334],"Stroke","Hypertonia","Dystonia","Rigidity","Hemiplegia",[336,337,338,339,340,341,342,343],"hypertonia","dystonia","rigidity","reliability","validity","hemiplegia","spasticity","stroke","2026-02-20",{"date":346,"type":37},"2026-02-24",{"date":348,"type":20},"2026-03-01",{"date":350,"type":20},"2026-10-01",{"name":42,"class":43},{"id":353,"slug":354,"hasResults":11,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":4,"eligibilityCriteria":358,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":359,"targetDuration":4,"studyType":94,"phases":4,"briefSummary":360,"conditions":361,"keywords":364,"overallStatus":370,"whyStopped":4,"lastUpdateSubmitDate":371,"lastUpdatePostDateStruct":372,"startDateStruct":374,"completionDateStruct":376,"leadSponsor":378,"locationsCount":44},"100618065","effect-of-ultrasound-guided-quadro-iliac-plane-block-on-postoperative-analgesia-after-lumbar-spinal-surgery-100618065","NCT07326774","Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal Surgery","Evaluation of the Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia in Patients Undergoing Lumbar Spinal Surgery","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Body mass index (BMI) \\\u003C35 kg\u002Fm²\n* Scheduled for elective posterior lumbar spinal instrumentation surgery under general anesthesia\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Emergency surgery\n* Local infection or hematoma at the block application site\n* Previous surgery at the block application site\n* Presence of coagulopathy\n* Known allergy or toxicity to local anesthetics\n* History of hematological, renal, or hepatic disease, or advanced respiratory or cardiac failure\n* Chronic analgesic use, chronic alcohol consumption, or substance abuse\n* Inability to speak Turkish or presence of language\u002Fcommunication barriers",{"count":115,"type":20},"This prospective observational study aims to evaluate the effect of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia in patients undergoing lumbar spinal surgery. Lumbar spinal procedures are commonly associated with significant postoperative pain, which may impair early mobilization and increase opioid consumption. In routine clinical practice, QIPB is increasingly used as part of multimodal analgesia to improve pain control and reduce opioid-related adverse effects.\n\nAdult patients scheduled for elective lumbar spinal surgery under general anesthesia will be followed according to routine clinical care. Postoperative analgesia will be managed with intravenous patient-controlled analgesia (PCA) using tramadol, with or without the addition of ultrasound-guided QIPB, based on the preference of the attending anesthesiologist. No intervention or treatment assignment will be performed by the investigators.\n\nPostoperative pain scores at rest and during movement, opioid consumption, need for rescue analgesics, incidence of nausea and vomiting, and patient satisfaction will be recorded during the first 24 hours after surgery. The findings of this study are expected to provide further clinical evidence regarding the effectiveness of QIPB as part of multimodal analgesia in lumbar spinal surgery.",[260,362,363],"Lumbar Spine Surgery","Postoperative Analgesia",[365,366,367,368,363,369],"Quadro-Iliac Plane Block","QIPB","Ultrasound-Guided Regional Anesthesia","Lumbar Spinal Surgery","Patient-Controlled Analgesia","RECRUITING","2026-02-19",{"date":373,"type":37},"2026-02-23",{"date":375,"type":37},"2026-01-05",{"date":377,"type":20},"2026-10",{"name":42,"class":43},{"id":380,"slug":381,"hasResults":11,"nctId":382,"briefTitle":383,"officialTitle":384,"acronym":385,"eligibilityCriteria":386,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":387,"targetDuration":4,"studyType":21,"phases":389,"briefSummary":390,"conditions":391,"keywords":396,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":407,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":413,"locationsCount":44},"100624025","oxygen-reserve-index-guided-oxygen-titration-during-surgery-in-the-beach-chair-position-100624025","NCT07404267","Oxygen Reserve Index-Guided Oxygen Titration During Surgery in the Beach Chair Position","The Utility of Oxygen Reserve Index Guidance in Inspiratory Oxygen Titration for Patients Undergoing Surgery in the Beach Chair Position: A Prospective Comparative Study","ORI-BCP","Inclusion Criteria:\n\n* Adult patients aged 18 to 65 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective orthopedic surgery in the beach chair position\n* Body mass index (BMI) \\\u003C35 kg\u002Fm²\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 or ≥65 years\n* Finger deformities preventing the use of Oxygen Reserve Index (ORi) monitoring\n* Severe anemia (hemoglobin \\\u003C8 g\u002FdL)\n* Pregnancy\n* Refusal or inability to provide informed consent\n* History of stroke or significant vascular pathology\n* Severe cardiac or respiratory disease",{"count":388,"type":20},80,[23],"This study aims to evaluate whether guidance by the Oxygen Reserve Index (ORi) improves inspiratory oxygen fraction (FiO₂) titration compared with conventional pulse oximetry (SpO₂)-guided oxygen administration in adult patients undergoing surgery in the beach chair position.\n\nOxygen therapy is routinely used during general anesthesia to prevent hypoxemia; however, excessive oxygen administration may result in hyperoxia, which has been associated with adverse cardiovascular and pulmonary effects. Standard pulse oximetry may not adequately detect hyperoxia when oxygen saturation values are high.\n\nIn this prospective comparative study, patients will receive oxygen titration guided either by SpO₂ alone or by combined ORi and SpO₂ monitoring. The primary outcome is the incidence of intraoperative hyperoxemia, assessed by arterial blood gas analysis. Secondary outcomes include intraoperative oxygenation parameters and hemodynamic variables.",[392,393,394,395],"Hyperoxemia","Intraoperative Oxygen Therapy","Beach Chair Position","Cerebral Oxygenation",[397,398,399,400,401,402,403,64,404,405],"Oxygen Reserve Index","ORİ","FiO2 titration","Hyperoxia","Pulse oximetry","Arterial blood gas","Near-infrared spectroscopy","Beach chair position","Orthopedic surgery","2026-02-09",{"date":408,"type":37},"2026-02-11",{"date":410,"type":20},"2026-02-15",{"date":412,"type":20},"2026-07-31",{"name":42,"class":43},{"id":415,"slug":416,"hasResults":11,"nctId":417,"briefTitle":418,"officialTitle":419,"acronym":420,"eligibilityCriteria":421,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":422,"targetDuration":4,"studyType":21,"phases":424,"briefSummary":425,"conditions":426,"keywords":430,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":437,"startDateStruct":438,"completionDateStruct":439,"leadSponsor":440,"locationsCount":44},"100624014","effects-of-ankle-block-on-postoperative-analgesia-in-diabetic-and-non-diabetic-patients-100624014","NCT07404124","Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients","Comparison of Sensory and Motor Block Characteristics and Postoperative Analgesic Consumption After Ultrasound-Guided Ankle Block in Diabetic and Non-Diabetic Patients Undergoing Lower Extremity Surgery","ANKLE-DM","Inclusion Criteria:\n\n* Adults aged 18 years and older.\n* Patients scheduled for lower extremity surgery under ultrasound-guided ankle block as part of routine clinical care.\n* Patients able to provide written informed consent.\n* Availability of complete perioperative data including blood glucose levels, -HbA1c values, pain scores, and postoperative analgesic consumption.\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent.\n* Failure of ankle block requiring conversion to another anesthesia technique.\n* Known coagulation disorders contraindicating peripheral nerve block.\n* Active infection at the site of block application.\n* Chronic opioid or analgesic use, chronic alcohol use, or substance abuse.\n* History of diabetic ketoacidosis or hyperosmolar hyperglycemic state.\n* Severe renal or hepatic insufficiency.\n* Known allergy to local anesthetics such as lidocaine or bupivacaine.\n* Inability to perform perioperative blood glucose monitoring.\n* Cognitive impairment or psychiatric conditions interfering with study participation or data collection.",{"count":423,"type":20},46,[23],"This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery. The study will compare diabetic and non-diabetic patients and will also assess the impact of glycemic control on block onset time and postoperative analgesic consumption.\n\nAnkle block is commonly used in patients undergoing foot and ankle surgery, particularly in those with diabetes, peripheral neuropathy, or vascular disease, when general or neuraxial anesthesia may not be suitable. Previous studies suggest that diabetic neuropathy and impaired glycemic control may influence the onset and duration of peripheral nerve blocks.\n\nAdult patients scheduled for lower extremity surgery under ankle block will be included. All procedures will be performed as part of routine clinical care, and no additional interventions will be applied for research purposes. Sensory and motor block onset times, postoperative pain scores, opioid consumption within the first 24 hours, and patient and surgeon satisfaction will be recorded.\n\nThe results of this study are expected to provide clinically relevant information regarding the effects of diabetes and glycemic control on ankle block characteristics and postoperative analgesia.",[427,428,429],"Diabetes Mellitus","Diabetic Neuropathy","Postoperative Pain Management",[431,367,432,427,428,433,363,434,435,436],"Ankle Block","Peripheral Nerve Block","Glycemic Control","HBA1C","Lower Extremity Surgery","Opioid Consumption",{"date":408,"type":37},{"date":348,"type":20},{"date":297,"type":20},{"name":42,"class":43},{"id":442,"slug":443,"hasResults":11,"nctId":444,"briefTitle":445,"officialTitle":446,"acronym":4,"eligibilityCriteria":447,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":326,"enrollmentInfo":448,"targetDuration":4,"studyType":21,"phases":449,"briefSummary":450,"conditions":451,"keywords":455,"overallStatus":370,"whyStopped":4,"lastUpdateSubmitDate":457,"lastUpdatePostDateStruct":458,"startDateStruct":460,"completionDateStruct":462,"leadSponsor":464,"locationsCount":44},"100619602","suprascapular-nerve-block-and-proprioception-in-hemiplegic-shoulder-pain-a-randomized-controlled-study-100619602","NCT07346755","Suprascapular Nerve Block and Proprioception in Hemiplegic Shoulder Pain: A Randomized Controlled Study","Effects of Suprascapular Nerve Block on Proprioception in Hemiplegic Shoulder Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Presence of shoulder pain on the hemiplegic side with a Numeric Rating Scale (NRS) score \\> 3\n* At least 1 month since the cerebrovascular event (subacute and chronic stroke patients)\n* Active shoulder flexion range of motion \\> 90 degrees (required for the application of the laser pointer-assisted joint position sense test)\n* First-ever, unilateral hemiplegia\n\nExclusion Criteria:\n\n* Mini-Mental State Examination score \\\u003C 24 indicating cognitive impairment\n* Presence of aphasia\n* Shoulder spasticity with a Modified Ashworth Scale score \\> 2\n* Brunnstrom upper extremity motor stage \\\u003C 3\n* Botulinum toxin type A injection within the last 3 months to muscles affecting shoulder joint movement (trapezius, levator scapulae, pectoralis major, deltoid, serratus anterior, latissimus dorsi, rhomboids, teres major, biceps, coracobrachialis, triceps, supraspinatus, subscapularis, infraspinatus, and teres minor)\n* Pre-existing shoulder pathology causing pain in the hemiplegic shoulder\n* Presence of neglect syndrome\n* Complex regional pain syndrome, central pain, traumatic brachial plexus injury\n* Change in pain medication during the study period\n* Hypersensitivity to the medication used for suprascapular nerve block (lidocaine)\n* Adhesive capsulitis (frozen shoulder)\n* Other shoulder pathologies such as fractures or joint replacement",{"count":231,"type":20},[23],"The purpose of this prospective randomized controlled clinical trial is to evaluate the effect of suprascapular nerve block on shoulder joint proprioception in stroke patients with hemiplegic shoulder pain.\n\nFourteen patients aged 18-80 years with hemiplegic shoulder pain will be randomized into two groups. One group will receive suprascapular nerve block followed by a standardized physical therapy program, while the control group will receive the same physical therapy program alone.\n\nThe primary outcome is shoulder joint proprioception. Secondary outcomes include pain intensity, shoulder range of motion, motor recovery, stroke-specific quality of life, and upper extremity functional outcomes.\n\nThe results of this study are expected to clarify the role of suprascapular nerve block on proprioception and rehabilitation outcomes in patients with hemiplegic shoulder pain.",[452,453,454],"Hemiplegic Shoulder Pain","Proprioception","Suprascapular Nerve Block",[452,453,456,334],"Suprascapular nerve block","2026-01-18",{"date":459,"type":37},"2026-01-21",{"date":461,"type":37},"2025-05-01",{"date":463,"type":20},"2026-05",{"name":42,"class":43},{"id":466,"slug":467,"hasResults":11,"nctId":468,"briefTitle":469,"officialTitle":470,"acronym":4,"eligibilityCriteria":471,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":142,"enrollmentInfo":472,"targetDuration":473,"studyType":94,"phases":4,"briefSummary":474,"conditions":475,"keywords":477,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":482,"lastUpdatePostDateStruct":483,"startDateStruct":485,"completionDateStruct":487,"leadSponsor":489,"locationsCount":44},"100573136","magnetic-resonance-imaging-parameters-in-patients-with-subacromial-impingement-syndrome-100573136","NCT06742359","Magnetic Resonance Imaging Parameters in Patients with Subacromial Impingement Syndrome","Relationship of Magnetic Resonance Imaging Parameters with Shoulder Function and Pain in Patients with Subacromial Impingement Syndrome","Inclusion Criteria:\n\n1. To be between the ages of 18-65\n2. Shoulder pain for at least six weeks\n\nExclusion Criteria:\n\n1. Presence of a rheumatologic disease,\n2. Presence of neurological disease\n3. Pregnancy\n4. Symptomatic osteoarthritis of the shoulder, shoulder instability, pathologies of the tendon of the long head of the biceps, glenoid injuries and partial tears greater than 3 mm and full-thickness tears of the rotator cuff\n5. Corticosteroid, hyaluronic acid and\u002For PRP injection in the shoulder area within the last 3 months",{"count":178,"type":20},"2 Months","Shoulder pain is the third most common musculoskeletal pain complaint in the world with an incidence of 7-30%. Subacromial impingement syndrome (SIS) is the most common cause of shoulder pain. Imaging in impingement syndrome is usually based on different imaging modalities. X-ray, magnetic resonance imaging (MRI) and ultrasound are the most commonly used, and MRI is considered by many authors to be the most reliable imaging modality for evaluation of the rotator cuff because it allows evaluation of soft tissues as well as bony abnormalities such as subacromial osteophytes and acromioclavicular joint capsular hypertrophy. MRI allows the diagnosis of rotator cuff tears with greater interobserver reliability than ultrasound in assessing tear size, retraction and atrophy. Few studies have investigated the impact of pathologic findings on MRI on the degree of symptoms and functional impairment seen in these patients. The aim of this study was to investigate the relationship between shoulder pain and function and MRI findings in patients with subacromial impingement syndrome.",[476],"Subacromial Impingement Syndrome",[478,479,480,481],"Subacromial impingement syndrome","pain","function","magnetic resonance imaging","2024-12-20",{"date":484,"type":37},"2024-12-27",{"date":486,"type":20},"2025-01-31",{"date":488,"type":20},"2025-04-30",{"name":42,"class":43},{"id":491,"slug":492,"hasResults":11,"nctId":493,"briefTitle":494,"officialTitle":495,"acronym":496,"eligibilityCriteria":497,"healthyVolunteers":52,"sex":16,"minAge":280,"maxAge":498,"enrollmentInfo":499,"targetDuration":205,"studyType":94,"phases":4,"briefSummary":500,"conditions":501,"keywords":503,"overallStatus":370,"whyStopped":4,"lastUpdateSubmitDate":508,"lastUpdatePostDateStruct":509,"startDateStruct":511,"completionDateStruct":513,"leadSponsor":515,"locationsCount":44},"100560097","ultrasonographic-evaluation-of-parasternal-intercostal-muscles-in-stroke-patients-100560097","NCT06572709","Ultrasonographic Evaluation of Parasternal Intercostal Muscles in Stroke Patients","Ultrasonographic Evaluation of Parasternal Intercostal Muscles and Their Correlation With Respiratory Function Test in Stroke Patients","UEPIMSP","Inclusion Criteria:\n\n* Ischemic or Hemorrhagic stroke patients, Stroke duration \\>6 months, Mini-mental test score \\>24\n\nExclusion Criteria:\n\n* Individuals with acute or chronic lung disease, Patients with a history of thoracic or abdominal surgery, Patients with other neuromuscular diseases, Aphasia type with impaired understanding, Facial paralysis","90 Years",{"count":115,"type":20},"Ultrasonographic evaluation of parasternal intercostal muscles and to determine whether there is a correlation with PFT parameters in stroke patients",[330,502],"Respiratory Muscle",[343,504,505,506,507],"intercostal muscle","pulmonary function test","respiratory muscle","ultrasound","2024-08-23",{"date":510,"type":37},"2024-08-27",{"date":512,"type":37},"2024-08-07",{"date":514,"type":20},"2024-09-04",{"name":42,"class":43},{"id":517,"slug":518,"hasResults":11,"nctId":519,"briefTitle":520,"officialTitle":521,"acronym":522,"eligibilityCriteria":523,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":524,"targetDuration":205,"studyType":94,"phases":4,"briefSummary":525,"conditions":526,"keywords":529,"overallStatus":370,"whyStopped":4,"lastUpdateSubmitDate":508,"lastUpdatePostDateStruct":533,"startDateStruct":534,"completionDateStruct":536,"leadSponsor":538,"locationsCount":44},"100560096","ultrasonographic-evaluation-of-asymptomatic-shoulder-joint-pathologies-in-rheumatoid-arthritis-patients-100560096","NCT06572696","Ultrasonographic Evaluation of Asymptomatic Shoulder Joint Pathologies in Rheumatoid Arthritis Patients","Ultrasonographic Evaluation of Asymptomatic Shoulder Joint Pathologies in Rheumatoid Arthritis Patients Compared to Healthy Controls: Case-Controlled Study","UEASJPRAP","Inclusion Criteria:\n\n* RA patients between the ages of 18-75 who has been diagnosed with RA for at least 12 months according to the 2010 American College of Rheumatology (ACR)\u002FEuropean League Against Rheumatism (EULAR) criteria and has no complaint of shoulder pain.\n\nExclusion Criteria:\n\n* Patients with clinically suspected shoulder pathology, a history of previous shoulder surgery, a history of direct trauma to the shoulder, a history of infectious arthritis, other connective tissue diseases, serious and chronic somatic or psychiatric diseases, any fracture in the upper extremities, and patients with limited joint movement.",{"count":115,"type":20},"Ultrasonographic determination of changes and degree of damage in asymptomatic shoulder joint periarticular structures in RA patients and comparison with healthy controls.",[527,528],"Rheumatoid Arthritis","Shoulder Injuries and Disorders",[530,531,532],"Rheumatoid arthritis","shoulder","shoulder impingement syndrome",{"date":510,"type":37},{"date":535,"type":37},"2024-08-12",{"date":537,"type":20},"2024-09-02",{"name":42,"class":43},""]