[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Federal University of Bahia\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":133},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,51,79,106],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100643344","transauricular-vagus-nerve-stimulation-frequencies-for-postoperative-pain-100643344",false,"NCT07633444","Transauricular Vagus Nerve Stimulation Frequencies for Postoperative Pain","Effects of Different Frequencies of Transauricular Vagus Nerve Stimulation on Postoperative Pain: A Randomized, Double-Blind, Sham-Controlled Trial With Preoperative and Postoperative Sessions","TVNS-PAIN","Inclusion Criteria:\n\n* Adults aged 18 to 59 years.\n* Undergoing elective abdominal or urologic surgery.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* History of neurological disorders.\n* History of psychiatric disorders.\n* Inability to understand study procedures.\n* Pregnancy.\n* Cognitive impairment.\n* Communication difficulties that interfere with study assessments.\n* Auricular dermatitis or skin lesions at the stimulation site.\n* Pre-existing cardiac arrhythmia.\n* Chronic opioid use.\n* Implanted electronic medical devices, including pacemakers.","ALL","18 Years","59 Years",{"count":21,"type":22},174,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn whether different frequencies of transauricular vagus nerve stimulation (tVNS) can reduce postoperative pain and opioid consumption in adults undergoing abdominal or urologic surgery. It will also evaluate the effects of tVNS on recovery quality, autonomic function, and treatment safety. The main questions it aims to answer are:\n\nDoes transauricular vagus nerve stimulation reduce postoperative opioid consumption during the first 24 hours after surgery? Do different stimulation frequencies (high-frequency and low-frequency tVNS) produce different effects on postoperative pain and autonomic responses? Is transauricular vagus nerve stimulation safe and well tolerated in surgical patients?\n\nResearchers will compare high-frequency tVNS, low-frequency tVNS, and sham stimulation (inactive stimulation) to determine their effects on postoperative pain and opioid requirements.\n\nParticipants will:\n\nBe randomly assigned to receive high-frequency tVNS, low-frequency tVNS, or sham stimulation.\n\nReceive two 30-minute stimulation sessions, one before anesthesia and one after surgery in the post-anesthesia care unit.\n\nUndergo assessments of postoperative pain, opioid consumption, need for rescue analgesics, postoperative nausea and vomiting, heart rate changes, and quality of recovery.\n\nBe monitored for adverse events related to the intervention during the study period.\n\nA total of 174 participants will be enrolled in this single-center, randomized, double-blind, sham-controlled clinical trial.",[28,29,30],"Postoperative Pain","Postoperative Nausea and Vomiting (PONV)","Opioid Consumption, Postoperative",[28,32,33,34,35,36,37],"Transauricular Vagus Nerve Stimulation","tVNS","Neuromodulation","Opioid Consumption","Pain Management","Randomized Controlled Trial","RECRUITING","2026-06-07",{"date":41,"type":42},"2026-06-10","ACTUAL",{"date":44,"type":22},"2026-06-01",{"date":46,"type":22},"2026-12-04",{"name":48,"class":49},"Federal University of Bahia","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":50},"100628192","parents-in-action-an-online-intervention-aimed-at-parents-well-being-100628192","NCT07458438","Parents in Action: An Online Intervention Aimed at Parents' Well-being","Evaluation of an Online Intervention to Promote Parental Well-being and Child Development","Inclusion Criteria:\n\n* parents of children between 3 and 6 years of age\n* parents must live with the child\n* child must attend public school\n\nExclusion Criteria:\n\n* parents under 19 years of age\n* child with chronic disease or genetic syndromes\n* lack of access to the internet or a digital device","19 Years",{"count":60,"type":22},150,[25],"The goal of this clinical trial is to learn if an online intervention improves well-being in low-income parents with children aged between 3 and 6 years. The main question\\[s\\] it aims to answer \\[is\u002Fare\\]:\n\n* Does life satisfaction improves after the online intervention?\n* Do stress, anxiety and depression symptoms diminish after the online intervention? Researchers will compare parents who took the online intervention with parents who did not to see if the intervention makes parents feel more satisfied with life and less stressed, anxious and depressed.\n\nParticipants will be interviewed about their own well-being, mental health and parenting practices and about their children's behavior and screen use before taking the online intervention.\n\nDuring the intervention, parents will watch videos, answer quizzes and do simple activities at home.\n\nAfter the online intervention, parents will be interviewed again about their own well-being, mental health and parenting practices and about their children's behavior and screen use before taking the online intervention.",[64,65],"Psychiatric Aspects","Psychosocial Aspects",[67,68,69,70],"parenthood","well-being","mental health","early childhood development","2026-03-09",{"date":73,"type":42},"2026-03-11",{"date":75,"type":42},"2024-06-01",{"date":77,"type":22},"2027-12-31",{"name":48,"class":49},{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":17,"minAge":87,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":50},"100524434","telepharmacy-on-patients-with-arterial-hypertension-100524434","NCT06108674","Telepharmacy on Patients With Arterial Hypertension","Evaluation of the Effectiveness of Telepharmacy on Clinical Outcomes of Patients With Arterial Hypertension: Celeste Randomized Clinical Trial","CELESTE","Inclusion Criteria:\n\n* Elderly patients admitted to the service with a diagnosis of systemic arterial hypertension made by a physician based on a patient report, report or medical prescription.\n* Patients who present uncontrolled blood pressure at the time of assessment based on the average of three measurements using a standardized protocol at the pharmacy will be included;\n* Patients must have a cell phone and know how to use it;\n* Patient not have previously received pharmaceutical care.\n\nExclusion Criteria:\n\n* Elderly people who are unable to use their cell phones due to cognitive impairments (Mini Mental State Examination (MMSE).\n* Elderly person considered unable of using a telephone (Instrumental Activities of Daily Living)\n* Elderly with controlled blood pressure according to home monitoring.","60 Years",{"count":89,"type":22},194,[25],"The goal of this clinical trial is to compare the effectiveness of a pharmaceutical care protocol via teleconsultation in the management of uncontrolled hypertension with pharmaceutical care carried out in elderly patients assisted in primary health care. The main questions it aims to answer are:\n\n1. How effective is a pharmaceutical care protocol via teleconsultation on the clinical outcomes of elderly people with uncontrolled hypertension, when compared to in-person pharmaceutical care?\n2. How effective is a pharmaceutical care protocol via teleconsultation in adherence to the treatment of elderly people with hypertension, when compared to in-person pharmaceutical care?\n\nParticipants will undergo four visits. Two visits will be for the application of instruments and measurement of clinical parameters to be carried out at the beginning and end of follow-up (visits 1 and 4). These will be carried out in a pharmacist's office at the pharmacy by previously trained pharmacists and pharmacy students. Visits 2 and 3 will be pharmaceutical consultations to be carried out in person and\u002For via telepharmacy.\n\nResearchers will compare pharmaceutical care via telepharmacy with in-person pharmaceutical care to see how effective these services are in controlling blood pressure in elderly patients with uncontrolled blood pressure.",[93],"Hypertension",[95,96,97],"pharmaceutical care","telepharmacy","elderly patients","2025-08-06",{"date":100,"type":42},"2025-08-12",{"date":102,"type":42},"2023-11-01",{"date":104,"type":22},"2026-03",{"name":48,"class":49},{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":23,"phases":117,"briefSummary":118,"conditions":119,"keywords":121,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":50},"100587454","effects-of-gpr-on-non-specific-chronic-low-back-pain-100587454","NCT06928597","Effects of GPR on Non-Specific Chronic Low Back Pain","Global Postural Reeducation (GPR) in the Treatment of Patients With Non-Specific Chronic Low Back Pain: A Randomized Sham-Controlled Clinical Trial","GPRSHAM","Inclusion Criteria:\n\n* Adults aged between 18 and 55 years with chronic non-specific low back pain,\n* Participants who voluntarily agree to participate and sign the Free and Informed Consent Form,\n* Participants who have never done any treatment with the GPR method, and\n* Participants who have not been undergoing physiotherapy treatment for at least 2 months.\n\nExclusion Criteria:\n\n* Patients with pain lumbar acute, or it is, with symptoms gifts there is less of dose weeks, what carried out blocking medicinal in the column us last six months;\n* Patients with hernia of disk of type extruded and\u002For kidnapped;\n* Patients in possess or be in investigation of any kind of neoplasia;\n* Patients who have undergone any type of surgery with placement of any type of prosthesis in the spine;\n* Intellectual or sensory disability that prevents them from understanding commands or describing symptoms;\n* Patients who have a significant change in tactile sensitivity that prevents them from reporting any symptoms;\n* Patients who have any type of vestibular changes;\n* Serious pathologies of the spine;\n* Amputation of upper or lower limbs;\n* Spinal Cord Injury;\n* Low back pain with sacroiliac irradiation; any type of rheumatic diseases, such as: Rheumatoid Arthritis, Fibromyalgia, and others;\n* Patients that be performing or carried out last two months any type of conservative treatments, such as: Acupuncture, hydrotherapy, manual therapy, Pilates, conventional physiotherapy, and others; and\n* Patients who have travel plans in the coming months.","55 Years",{"count":116,"type":22},42,[25],"Introduction: Low back pain affects approximately 18.5% of the Brazilian population in adulthood, significantly impacting the quality of life and generating substantial costs for the health system. The Global Postural Reeducation Method (GPR) is a promising therapeutic alternative due to its multidimensional approach, capable of improving postural control and reducing pain. Objectives: to evaluate the Efficacy of the RPG method compared to simulated RPG (SHAM) in treating patients with chronic nonspecific low back pain. Methods: Randomized sham-controlled clinical trial. Forty-two adult individuals with chronic nonspecific low back pain will be recruited and distributed into two groups: the Experimental Group (EG), which will receive GPR sessions, and the Control Group (CG), which will receive RPG-SHAM sessions. Both groups will be treated for 30 minutes once a week for 8 weeks. Descriptive analysis will be performed, continuous variables will be summarized to the mean, and standard deviation and categorical variables will be summarized as absolute and relative frequencies. To assess the effects of the intervention over team, analysis of variance (ANOVA) with repeated measures will be used, with a significance level of 5% (p \\\u003C 0.05). Expected Results: This study is expected to provide robust evidence on the effectiveness of RPG in treating patients with low back pain, contributing to a better understanding of this complex health condition. The results will potentially positively impact the clinical practice of Orthopedic Physiotherapy, offering an exercise-based and accessible approach for treating patients with low back pain.",[120],"Low Back Pain",[122,123,124],"Low back pain","Global Posture Reeducation","Chronic Pain","2025-08-04",{"date":127,"type":42},"2025-08-05",{"date":129,"type":42},"2025-06-01",{"date":131,"type":22},"2026-12-01",{"name":48,"class":49},""]