[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fenerbahce University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":691},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,31,0,25,[9,53,82,112,137,160,186,208,235,265,293,322,349,379,404,432,466,497,524,552,573,597,621,649,673],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100640580","structured-combined-exercise-program-in-postmenopausal-women-effects-on-heart-rate-variability-and-menopausal-symptoms-100640580",false,"NCT07615790","Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms","The Effect of a Structured Combined Exercise Program on Heart Rate Variability and Menopausal Symptoms in Postmenopausal Women: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Women in the postmenopausal period\n* Aged between 45 and 65 years\n* Able to communicate and cooperate with the researchers\n* Not participating in another structured exercise program\n* Willing to participate voluntarily in the study\n\nExclusion Criteria:\n\n* Presence of severe cardiovascular, neurological, orthopedic, or psychiatric disease\n* Hormone replacement therapy use during the study period\n* Cognitive impairment affecting participation\n* Uncontrolled hypertension or other unstable medical conditions\n* Regular participation in structured exercise training within the last 6 months\n* Smoking or alcohol use that may affect heart rate variability measurements","FEMALE","45 Years","65 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn whether a structured combined exercise program can improve heart health, menopausal symptoms, sleep quality, and quality of life in postmenopausal women aged 45 to 65 years.\n\nThe main questions it aims to answer are:\n\nDoes the exercise program improve heart rate variability, which shows how well the heart is controlled by the nervous system? Does the exercise program lower menopausal symptoms? Does the exercise program improve sleep quality and quality of life?\n\nResearchers will compare women who join the exercise program with women who continue their usual daily activities.\n\nParticipants in the exercise group will take part in a supervised exercise program for 12 weeks. They will exercise 2 days each week. Each session will last 45 minutes and will include warm-up, balance, strengthening, coordination, flexibility, and cool-down exercises.\n\nParticipants in the control group will continue their usual daily activities during the study.",[28,29,30,31],"Postmenopausal","Menopausal Symptoms","Autonomic Nervous System Diseases","Sleep Wake Disorders",[33,34,35,36,37,38,39],"Structured combined exercise","Postmenopausal women","Heart rate variability","Cardiac autonomic function","Menopausal symptoms","Sleep quality","Quality of life","RECRUITING","2026-05-28",{"date":43,"type":44},"2026-05-29","ACTUAL",{"date":46,"type":44},"2026-04-27",{"date":48,"type":22},"2026-09",{"name":50,"class":51},"Fenerbahce University","OTHER",1,{"id":54,"slug":55,"hasResults":12,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100639314","development-and-evaluation-of-the-effectiveness-of-patient-gowns-for-patients-undergoing-abdominal-surgery-100639314","NCT07607457","Development and Evaluation of the Effectiveness of Patient Gowns for Patients Undergoing Abdominal Surgery","Patient Inclusion Criteria for the Study:\n\n* Be 18 years of age or older\n* Have undergone major abdominal surgery performed on an elective basis in a general surgery clinic (e.g., colorectal surgery, gastric surgery, hepatobiliary surgery, etc.)\n* Currently receiving care and treatment with medical devices (e.g., drains, Foley catheters, etc.)\n* Willing to participate in the study\n\nPatient Inclusion Criteria for the Study:\n\n* The participant refuses to wear a hospital gown\n* The participant has an allergy to the specified fabric Patients who are unable to mobilize for any reason (paralysis, general health impairment, history of stroke, etc.)\n* Patients with difficulty speaking and understanding Turkish\n* Patients lacking cognitive competence\n* Patients who develop complications within the first 24 hours after surgery and require revision surgery\n* Patients with prolonged intensive care unit (ICU) stays during the postoperative period\n* Since both the standard-sized traditional patient gown and the newly developed patient gown (available in sizes M-L) will be used in the study, patients whose body measurements do not fit within this size range will not be included in the study. This approach was adopted to prevent differences in comfort, mobility, and safety resulting from size mismatch from influencing the results, to ensure standardization in measurements, and to maintain comparability between the intervention and control groups.\n\nInclusion Criteria for Healthcare Professionals in the Study:\n\n* Providing care to patients who have undergone abdominal surgery\n* Having worked in the field for more than one year\n* Volunteering to participate in the study\n\nExclusion Criteria for Healthcare Professionals in the Study:\n\n• Being on leave or on sick leave during the study period.","ALL","18 Years",{"count":62,"type":22},172,[25],"Traditional hospital gowns fail to protect patient privacy due to their design features, restrict freedom of movement and are incompatible with medical equipment. This situation negatively affects both patient satisfaction and the quality of care. The limited number of studies addressing this issue in the literature highlights the unique value of the topic. This project will be conducted with a randomized controlled design to develop a functional and ergonomic hospital gown suitable for clinical requirements for patients undergoing abdominal surgery and to evaluate its effectiveness. During the design process, priority will be given to privacy, ease of mobilization and integration with medical devices.\n\nThe study first plans to produce a prototype of a cotton fabric apron. Technical modeling will be conducted in collaboration with the Department of Textile and Fashion Design at Bahçeşehir University; the prototype will then be evaluated for clinical suitability. In the second phase, an experimental study will be conducted at Medicana Hospital in Ataşehir, Istanbul, to assess the apron's effectiveness. The sample size was determined using power analysis to include 86 patients in each of the control and intervention groups, for a total of 172 patients, and 14 healthcare professionals will participate in the study. Patient and healthcare professional identification forms, along with patient apron evaluation questionnaires, will be used as data collection tools.\n\nThe study consists of five main work packages: (1) obtaining the necessary permits and registering the research, (2) selecting materials and determining fabric properties, (3) technical modeling and design work, (4) patient trials, and (5) data analysis. Interdisciplinary collaboration will be maintained throughout the process, and the final model will be developed through iterative prototyping and pilot trials.\n\nThe widespread impact of the project is expected to increase the quality of clinical care by enhancing the comfort and safety of surgical patients, facilitating the workflow of healthcare professionals and promoting sustainable textile usage. In addition, the commercialization of the developed product has the potential to make an economic contribution to the domestic textile sector.",[66],"Abdominal Surgery Patients",[68,69,70,71,72],"Abdominal surgery","Patient gown","Functional design","Clinical care","Privacy","NOT_YET_RECRUITING","2026-05-22",{"date":76,"type":44},"2026-05-27",{"date":78,"type":22},"2026-06-01",{"date":80,"type":22},"2026-12-31",{"name":50,"class":51},{"id":83,"slug":84,"hasResults":12,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":17,"minAge":60,"maxAge":19,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":92,"briefSummary":93,"conditions":94,"keywords":99,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":4},"100639382","the-impact-of-ai-powered-training-on-gynecological-examination-anxiety-and-satisfaction-100639382","NCT07599358","The Impact of AI-Powered Training on Gynecological Examination Anxiety and Satisfaction","Digital Transformation in Women's Health: The Impact of AI-Powered Training on Gynecological Examination Anxiety and Satisfaction","Inclusion Criteria:\n\n* Applying to the outpatient clinic for a gynecological examination\n* Being between 18-65 years of age\n* Agreeing to participate in the study\n\nExclusion Criteria:\n\n* Communication barrier\n* Having a psychological diagnosis,\n* Being pregnant",true,{"count":91,"type":22},114,[25],"Gynecological cancers, particularly cervical, ovarian, and endometrial cancers, pose a global problem. Cervical cancers are quite common worldwide, and this rate is even higher in developing countries. Cervical cancers are easily treatable when detected early, and screening is quite easy. Diagnosis is routinely made through human papillomavirus (HPV) testing and cytological screening. Eliminating anxiety, fear, and uncertainty about gynecological examinations makes the examination process easier, thus enabling early diagnosis and treatment of diseases. Keeping up with developing and changing technology and using it to improve women's health is an undeniable change in recent times. This study aims to determine the effect of an AI-assisted informational training program on women's anxiety and satisfaction levels regarding gynecological examinations.",[95,96,97,98],"Gynecological Examination","Artificial Intelligence (AI)","Patient Satisfaction","Anxiety",[100,101,102,103],"gynecological examination","artificial intelligence","patient satisfaction","anxiety","2026-05-14",{"date":106,"type":44},"2026-05-20",{"date":108,"type":22},"2026-05-02",{"date":110,"type":22},"2026-09-29",{"name":50,"class":51},{"id":113,"slug":114,"hasResults":12,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":12,"sex":17,"minAge":19,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":23,"phases":121,"briefSummary":122,"conditions":123,"keywords":125,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":52},"100635360","effects-of-action-observation-and-metaphorical-imagery-in-pelvic-floor-muscle-training-for-geriatric-urinary-incontinence-100635360","NCT07551674","Effects of Action Observation and Metaphorical Imagery in Pelvic Floor Muscle Training for Geriatric Urinary Incontinence","Investigation of the Effects of Pelvic Floor Muscle Training Applied Via Action Observation Method Accompanied by Metaphorical Imagery on Urinary Incontinence in Geriatric Women","Inclusion Criteria:\n\n* Diagnosed with stress or stress-predominant mixed urinary incontinence by a physician\n* Women aged 65 years and older\n* Literate in Turkish to understand, interpret, and answer the questionnaires\n* Scoring 24 or higher on the Mini-Mental State Examination (MMSE)\n* Able to walk independently without the use of any walking aids (assistive devices)\n* Having signed the informed consent form\n\nExclusion Criteria:\n\n* Received pelvic floor muscle training within the past 6 months\n* Presence of fecal incontinence\n* Current genitourinary infection or use of medication for urinary incontinence\n* History of urinary incontinence surgery or presence of symptomatic pelvic organ prolapse\n* Presence of neurological, orthopedic, psychiatric, hematological, or cardiovascular conditions that would preclude participation in exercise\n* Body mass index (BMI) ≥ 25 kg\u002Fm²\n* Hearing or visual impairments that would negatively affect participation\n* Presence of hematuria, urethral and\u002For bladder fistula, or a history of pelvic surgery","80 Years",{"count":21,"type":22},[25],"This clinical trial investigates the effects of a 12-week Pelvic Floor Muscle Training (PFMT) program applied via Action Observation Therapy (AOT) with metaphorical imagery on urinary incontinence, quality of life, and treatment adherence in geriatric women. The study will be conducted between June 2025 and June 2026 in nursing homes in Istanbul, targeting women aged 65 and older who are diagnosed with stress or stress-predominant mixed urinary incontinence, possess normal cognitive function (Standardized Mini Mental Test score ≥ 24), and walk independently. Eligible participants will be divided into groups, where both will undergo a progressive exercise regimen involving twice-weekly 45-50 minute group sessions that advance from supine positions to standing and jumping movements. However, the AOT study group will uniquely perform these exercises while observing and imagining projected metaphor-themed visuals to enhance motor learning and motivation. Efficacy will be evaluated pre- and post-intervention using various standardized tools, including the Pelvic Floor Distress Inventory-20, a 24-hour pad test, the Incontinence Severity Index, the Movement Imagery Questionnaire-3, and the Incontinence Quality of Life Scale, to comprehensively assess improvements in incontinence severity, functional status, and overall well-being.",[124],"Urinary Continence",[126,127,128],"urinary incontinence","geriatrics","action observation","2026-05-08",{"date":131,"type":44},"2026-05-11",{"date":133,"type":44},"2025-03-19",{"date":135,"type":22},"2026-09-01",{"name":50,"class":51},{"id":138,"slug":139,"hasResults":12,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":89,"sex":59,"minAge":60,"maxAge":144,"enrollmentInfo":145,"targetDuration":147,"studyType":148,"phases":4,"briefSummary":149,"conditions":150,"keywords":4,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":158,"leadSponsor":159,"locationsCount":52},"100636687","plantar-pressure-and-pain-in-young-adults-100636687","NCT07568925","Plantar Pressure and Pain in Young Adults","Investigation of the Relationship Between Plantar Pressure Distribution and Pain Localization and Severity in Young Adults","Inclusion Criteria:\n\n* Young adults aged between 18 and 35 years\n* Ability to stand and walk independently\n* Adequate cognitive function to understand and follow the measurement procedures\n* Willingness to participate voluntarily and provide written informed consent\n* Absence of acute lower extremity pain or injury on the day of assessment\n* Not using any assistive devices (e.g., orthoses, canes) during measurement\n\nExclusion Criteria:\n\n* History of a foot deformity diagnosed during childhood\n* History of musculoskeletal injury involving the lower extremity or lumbar region within the past 12 months\n* Previous surgery involving the lower extremity or lumbar region\n* Any condition that may affect general motor function, balance, circulation, sensory function, or pain perception","35 Years",{"count":146,"type":22},53,"1 Day","OBSERVATIONAL","The musculoskeletal system represents a holistic movement organization emerging from the integrated function of the central nervous system, musculoskeletal structures, and joint complexes. This organization is defined in the literature as the kinetic chain, characterized by the sequential and coordinated activation of body segments to enable distal segments to perform activities with optimal speed, position, and timing. The efficiency of the kinetic chain depends on optimal length-tension relationships, neuromuscular control, and balanced load transfer between segments. As the initial point of contact with the ground, the foot functions not merely as a passive support surface but as a dynamic structure actively involved in postural control, balance, and the regulation of ground reaction forces. Plantar pressure distribution and Center of Pressure (CoP) dynamics are considered objective indicators of foot-ground interaction. Due to its complex anatomical and biomechanical structure, any mechanical disturbance within the foot can influence the loading patterns of the entire kinetic chain.Abnormal plantar pressure distribution-characterized by increased peak pressures, altered forefoot-rearfoot load ratios, and increased CoP variability-may lead to compensatory load redistribution in proximal joints. These compensations have been associated with altered motor strategies, reduced neuromuscular control, and impaired shock absorption. Consequently, such alterations may contribute to the development of pain in proximal regions. This suggests a potential association between plantar pressure patterns and pain localization and severity in young adults.",[151,152,153],"Young Adult","Plantar Pressure Distrubution","Pain","2026-05-01",{"date":156,"type":44},"2026-05-06",{"date":154,"type":22},{"date":154,"type":22},{"name":50,"class":51},{"id":161,"slug":162,"hasResults":12,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":168,"enrollmentInfo":169,"targetDuration":4,"studyType":148,"phases":4,"briefSummary":171,"conditions":172,"keywords":175,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":185,"locationsCount":52},"100631529","investigation-of-digital-media-use-in-patients-receiving-chemotherapy-100631529","NCT07501871","Investigation of Digital Media Use in Patients Receiving Chemotherapy","Assessment of Digital Meda Use and eHealth Literacy in Patients Receiving Chemotherapy","DMU-CH","Inclusion Criteria:\n\n* Patients aged between 18 and 67 years\n* Receiving chemotherapy treatment\n* Able to communicate and understand the study procedures\n* Voluntarily agree to participate in the study\n\nExclusion Criteria:\n\n* Patients with cognitive impairment or communication difficulties\n* Patients who refuse to participate\n* Patients with incomplete questionnaire responses","67 Years",{"count":170,"type":22},80,"This study aims to examine digital media use and eHealth literacy among patients receiving chemotherapy. Digital media has become an important tool for accessing health information, communicating with healthcare providers, and supporting self-management.\n\nThis observational study will be conducted with adult patients receiving chemotherapy in an outpatient setting. Data will be collected using a sociodemographic information form and the eHealth Literacy Scale (eHEALS). The findings are expected to contribute to a better understanding of digital media use and digital health literacy levels in chemotherapy patients.",[173,174],"Cancer","Chemotherapy",[176,177,178],"Oncology Nursing","Digital Media","eHealth Literacy","2026-04-16",{"date":181,"type":44},"2026-04-21",{"date":183,"type":22},"2026-04-20",{"date":106,"type":22},{"name":50,"class":51},{"id":187,"slug":188,"hasResults":12,"nctId":189,"briefTitle":190,"officialTitle":190,"acronym":4,"eligibilityCriteria":191,"healthyVolunteers":89,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":192,"targetDuration":4,"studyType":148,"phases":4,"briefSummary":193,"conditions":194,"keywords":196,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":207,"locationsCount":52},"100632516","evalution-of-the-effectiveness-of-a-shoulder-dystocia-training-program-designed-with-inverted-learning-supported-by-generative-artificial-intelligence-100632516","NCT07514702","Evalution of the Effectiveness of a Shoulder Dystocia Training Program Designed With Inverted Learning Supported by Generative Artificial Intelligence","Inclusion Criteria:\n\n* -Being a 3rd year student in the Midwifery Department of Fenerbahçe University and Istanbul-Cerrahpaşa Faculty of Health Sciences.\n* Having sufficient or unlimited internet access.\n\nExclusion Criteria:\n\n* Having previously taken a course on shoulder dystocia\n* Student's absence from class\u002Fsick leave",{"count":91,"type":22},"With the ongoing digital transformation in health education, the importance of learner-centered and technology-integrated approaches has been increasing. Particularly in teaching complex and unpredictable clinical situations in healthcare, the limited effectiveness of traditional methods has led to a growing need for innovative approaches such as flipped learning and self-directed learning. Generative artificial intelligence (GAI)-supported educational applications have the potential to enhance academic achievement by making the learning process more interactive. However, research evaluating the effectiveness of these technologies in education remains limited. In this context, GAI-supported flipped learning enables students to gain individualized learning experiences through simulated classroom or clinical environments and to be better prepared for clinical encounters and specific clinical skill training. One of the critical clinical topics that should be addressed within this framework is shoulder dystocia. Shoulder dystocia is an obstetric emergency, most cases of which are unpredictable and unavoidable. Accordingly, this study aims to evaluate the effects of a GAI-supported flipped learning approach applied to shoulder dystocia training on midwifery students' knowledge levels and self-directed learning skills through effective use of technology.",[195],"Shoulder Dystocia Training Using AI-supported Flipped Learning in Midwifery Education",[197,198,199,200],"shoulder dystocia","flipped learning","midwifery education","Generative Artificial Intelligence","2026-04-13",{"date":179,"type":44},{"date":204,"type":22},"2026-04",{"date":206,"type":22},"2027-06",{"name":50,"class":51},{"id":209,"slug":210,"hasResults":12,"nctId":211,"briefTitle":212,"officialTitle":213,"acronym":4,"eligibilityCriteria":214,"healthyVolunteers":89,"sex":59,"minAge":19,"maxAge":4,"enrollmentInfo":215,"targetDuration":4,"studyType":23,"phases":217,"briefSummary":218,"conditions":219,"keywords":223,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":234,"locationsCount":52},"100633343","effects-of-three-different-exercise-programs-on-dynamic-balance-in-community-dwelling-older-adults-100633343","NCT07525453","Effects of Three Different Exercise Programs on Dynamic Balance in Community-Dwelling Older Adults","Effects of Three Different Exercise Programs on Dynamic Balance in Community-Dwelling Older Adults: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 65 years and older\n* Ability to walk independently\n* Mini-Mental State Examination (MMSE) score \\> 24, indicating sufficient cognitive ability to understand and follow instructions\n* Willingness to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* History of serious lower extremity injury, surgery, or acute musculoskeletal condition within the last 6 months\n* Severe visual or hearing impairment that would prevent safe and accurate completion of the assessments\n* Presence of acute vestibular disorders significantly affecting balance\n* Presence of neurological disease\n* Uncontrolled cardiac disease, uncontrolled hypertension, severe pulmonary disease, or any condition that makes exercise unsafe",{"count":216,"type":22},45,[25],"This study aims to compare the effects of core stabilization exercises, an amplitude-based exercise program derived from LSVT BIG principles, and their combination on dynamic balance in community-dwelling healthy older adults aged 65 years and above. Secondary outcomes include functional mobility, fear of falling, reaction time, and quality of life.\n\nAge-related declines in neuromuscular and sensory functions impair postural control and increase fall risk. While both core stabilization and amplitude-based exercises have shown beneficial effects, their comparative and combined effects in healthy older adults remain unclear. This study will determine whether the combined intervention provides additional benefits over single interventions.",[220,221,222],"Balance Disorders","Aging","Risk of Falling in the Elderly",[224,225,226,227],"Dynamic Balance","Older Adults","Postural Control","Reaction Time","2026-04-12",{"date":230,"type":44},"2026-04-15",{"date":232,"type":44},"2026-03-16",{"date":131,"type":22},{"name":50,"class":51},{"id":236,"slug":237,"hasResults":12,"nctId":238,"briefTitle":239,"officialTitle":240,"acronym":4,"eligibilityCriteria":241,"healthyVolunteers":89,"sex":59,"minAge":242,"maxAge":243,"enrollmentInfo":244,"targetDuration":4,"studyType":148,"phases":4,"briefSummary":246,"conditions":247,"keywords":252,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":52},"100632267","development-sensory-profile-and-sleep-quality-in-preschool-children-across-different-caregiving-models-100632267","NCT07511465","Development, Sensory Profile, and Sleep Quality in Preschool Children Across Different Caregiving Models","Developmental Status, Sensory Processing, and Sleep Quality in Preschool Children Across Different Caregiving Models","Inclusion Criteria:\n\n* Preschool children aged 3 to 6 years\n* Child has been raised within the same primary caregiving model for at least the past 6 months\n* Parent or legal guardian is willing to participate voluntarily and provide informed consent\n* Child and caregiver are able to understand Turkish and follow the study instructions\n\nExclusion Criteria:\n\n* Previously diagnosed neurological, developmental, or psychiatric disorder (e.g., autism spectrum disorder, attention-deficit\u002Fhyperactivity disorder, developmental delay)\n* Currently receiving treatment or therapy for sensory processing problems, sleep problems, or developmental difficulties\n* Parent or legal guardian provides incomplete or incorrect study forms\n* Child is unable to cooperate with or complete the assessment procedures","3 Years","6 Years",{"count":245,"type":22},135,"This observational study aims to examine developmental status, sensory processing, and sleep quality in preschool children aged 3 to 6 years across different caregiving models. Children raised primarily by first-degree relatives, second-degree relatives, caregivers, or in daycare settings will be compared. Data will be collected using the Denver II Developmental Screening Test, the Dunn Sensory Profile, and the Tayside Children's Sleep Questionnaire. The study will also evaluate the relationships among developmental status, sensory processing, and sleep quality, and explore whether caregiving model is associated with differences in these outcomes.",[248,249,250,251],"Child Development","Sensory Processing","Sleep Quality","Caregiving Models",[253,254,255,38,256],"Preschool children","Developmental status","Sensory processing","Caregiving models","2026-04-05",{"date":259,"type":44},"2026-04-09",{"date":261,"type":44},"2026-01-05",{"date":263,"type":22},"2026-06",{"name":50,"class":51},{"id":266,"slug":267,"hasResults":12,"nctId":268,"briefTitle":269,"officialTitle":270,"acronym":271,"eligibilityCriteria":272,"healthyVolunteers":12,"sex":59,"minAge":273,"maxAge":119,"enrollmentInfo":274,"targetDuration":4,"studyType":23,"phases":276,"briefSummary":277,"conditions":278,"keywords":281,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":52},"100577092","effect-of-transcutaneous-auricular-vagus-nerve-stimulation-application-on-respiratory-functions-in-stroke-patients-100577092","NCT06793800","Effect of Transcutaneous Auricular Vagus Nerve Stimulation Application on Respiratory Functions in Stroke Patients","Effect of TAVNS Application on Respiratory Functions in Stroke Patients","TAVNS","Inclusion Criteria:\n\n* Being a chronic stroke patient with an ischemic or hemorrhagic stroke diagnosis made 1-3 years ago\n* Having been diagnosed with stroke for the first time\n* Ability to understand and follow simple verbal instructions\n* Being between the ages of 40 and 80\n* No conditions affecting perioral muscles, such as facial paralysis or swallowing disorders\n* No visual, auditory, or communication problems\n* No cardiopulmonary disorders\n* No additional neurological, cardiovascular, orthopedic, or similar conditions causing balance problems\n* Mini Mental State Examination (MMSE) score ≥24\n* No surgical operations or Botox applications in the last 6 months\n* Scoring 2 or below on the Modified Ashworth Scale\n\nExclusion Criteria:\n\n* Presence of infection, ulcer, or scar on the auricle\n* Metallic implants in the skull, hypersensitivity, injury, or inflammation inside the ear\n* Chronic pulmonary and\u002For cardiac diseases\n* Resting heart rate below 60 beats per minute\n* Devices such as pacemakers or cochlear implants\n* Uncontrolled hypertension\n* Chronic obstructive pulmonary disease (COPD) or asthma unrelated to stroke\n* History of surgical operation or Botox application within the last 6 months\n* Presence of aphasia, apraxia, or neglect syndrome\n* History of 2 or more strokes (SVO)\n* Comorbid conditions affecting respiratory functions (e.g., Multiple Sclerosis, Parkinson's, spinal cord injury, contractures, deformities after fractures, active upper or lower respiratory infections, etc.)\n* Lack of cooperation","40 Years",{"count":275,"type":22},50,[25],"The purpose of this study is to evaluate the effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation (TAVSS) in improving respiratory muscle strength and function in chronic stroke patients. It aims to explore TAVSS as a potential complementary approach in enhancing rehabilitation outcomes for this population.",[279,280],"Hemiplegia","Respiratory Function Loss",[282,283,284],"hemiplegia","Vagus Nerve Stimulation","Respiration","2026-03-31",{"date":287,"type":44},"2026-04-01",{"date":289,"type":44},"2025-08-05",{"date":291,"type":22},"2027-07-30",{"name":50,"class":51},{"id":294,"slug":295,"hasResults":12,"nctId":296,"briefTitle":297,"officialTitle":298,"acronym":4,"eligibilityCriteria":299,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":119,"enrollmentInfo":300,"targetDuration":4,"studyType":23,"phases":302,"briefSummary":303,"conditions":304,"keywords":307,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":321,"locationsCount":52},"100628078","hiit-vs-mcit-for-stroke-related-sarcopenia-in-ischemic-stroke-100628078","NCT07456956","HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke","The Effect of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training on Sarcopenia and Clinical Outcomes in Patients With Ischemic Stroke: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* First-ever stroke.\n* Age 18 years or older.\n* Diagnosis of ischemic stroke.\n* Stroke duration between 1-6 months (subacute phase).\n* Modified Rankin Scale score \\\u003C 3.\n* Mini-Mental State Examination (MMSE) score ≥ 24.\n* Brunnstrom lower extremity motor stage between Stage III-V.\n* Lower extremity functional capacity sufficient to allow exercise participation (able to ambulate at least with an assistive device).\n* Lower extremity spasticity ≤ 2 according to the Modified Ashworth Scale.\n* Independent sitting balance (able to sit unsupported for at least 30 seconds).\n* Presence of sufficient voluntary active movement in the lower extremity to permit exercise application.\n* Ability to communicate.\n* Willingness to participate in the study and provision of written informed consent.\n\nExclusion Criteria:\n\n* Presence of hemispatial neglect.\n* History of recurrent stroke.\n* Presence of a psychiatric disorder.\n* Presence of orthopedic, neurological, or cardiopulmonary conditions that would contraindicate the planned exercise protocols.",{"count":301,"type":22},32,[25],"The aim of this study is to investigate the effect of post-stroke sarcopenia on prognosis and clinical outcomes in patients with ischemic stroke and to compare the effects of High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MCIT) exercise programs on muscle mass, as well as on functional capacity, quality of life, and clinical outcomes.",[305,306],"Stroke, Ischemic","Sarcopenia",[308,309,310,311,312,313],"Ischemic Stroke","Stroke-Related Sarcopenia","HIIT","MCIT","Exercise Training","Muscle Thickness","2026-03-22",{"date":316,"type":44},"2026-03-25",{"date":318,"type":44},"2026-03-02",{"date":320,"type":22},"2027-06-06",{"name":50,"class":51},{"id":323,"slug":324,"hasResults":12,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":89,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":329,"targetDuration":4,"studyType":23,"phases":331,"briefSummary":332,"conditions":333,"keywords":336,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":342,"lastUpdatePostDateStruct":343,"startDateStruct":345,"completionDateStruct":346,"leadSponsor":348,"locationsCount":52},"100630668","impact-of-artificial-intelligence-discussion-on-midwifery-students-100630668","NCT07490665","Impact of Artificial Intelligence Discussion on Midwifery Students","The Impact of Artificial Intelligence-Assisted Case Discussion on Artificial Intelligence Attitude, Usage and Proficiency Among Midwifery Students","Inclusion Criteria:\n\n* Being a 3rd\u002F4th year student in the Midwifery department\n* Having previously taken courses on Healthy and High-Risk Pregnancy\n* Having prepared and presented at least one midwifery care plan\n\nExclusion Criteria:\n\n* Using more than 20% absenteeism in field applications",{"count":330,"type":22},81,[25],"This study aimed to examine the effect of artificial intelligence-assisted case discussions on midwifery students' use and proficiency of artificial intelligence technologies and their clinical competency levels. With the rapid development of artificial intelligence, its integration into healthcare education has become increasingly important. Supporting case-based learning with AI tools may enhance students' clinical decision-making, problem-solving, and critical thinking skills. Therefore, this study evaluates the contribution of AI-assisted educational approaches to the professional development of midwifery students.",[334,335],"Healthy","Student",[337,338,339,340,341],"Artificial Intelligence","Midwifery","Clinical Competence","Problem-Based Learning","Health Occupations","2026-03-18",{"date":344,"type":44},"2026-03-24",{"date":232,"type":22},{"date":347,"type":22},"2026-07-20",{"name":50,"class":51},{"id":350,"slug":351,"hasResults":12,"nctId":352,"briefTitle":353,"officialTitle":354,"acronym":4,"eligibilityCriteria":355,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":119,"enrollmentInfo":356,"targetDuration":147,"studyType":148,"phases":4,"briefSummary":358,"conditions":359,"keywords":363,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":371,"lastUpdatePostDateStruct":372,"startDateStruct":374,"completionDateStruct":376,"leadSponsor":378,"locationsCount":52},"100627374","diaphragm-morphology-and-respiratory-muscle-strength-in-subacute-hemiplegic-patients-100627374","NCT07447804","Diaphragm Morphology and Respiratory Muscle Strength in Subacute Hemiplegic Patients","The Relationship Between Diaphragm Morphology and Respiratory Muscle Strength in Subacute Hemiplegic Patients: A Cross-Sectional Study","Inclusion Criteria:\n\n* Adults aged 18-80 years\n* Clinical diagnosis of hemiplegia\n* Subacute phase (1-6 months post-onset)\n* Ability to tolerate diaphragm ultrasonography and MIP\u002FMEP measurements\n* MMSE score ≥ 24\n* Adequate level of consciousness and ability to cooperate\n\nExclusion Criteria:\n\n* Respiratory comorbidities such as COPD, asthma, or interstitial lung disease\n* Diaphragmatic paralysis or severe chest wall deformity\n* Acute cardiopulmonary conditions preventing respiratory function testing\n* Severe cognitive impairment that may affect measurements\n* Inability to perform ultrasound assessment due to prior gastric or abdominal surgery",{"count":357,"type":22},38,"The aim of this study is to determine the relationship between diaphragm morphology (diaphragm excursion, end-inspiratory and end-expiratory diaphragm thickness, and thickening fraction) and respiratory muscle strength (maximum inspiratory pressure - MIP and maximum expiratory pressure - MEP) in patients with subacute hemiplegia.",[360,361,362],"Stroke","Hemiplegia Following Ischemic Stroke","Diaphragm Ultrasonography",[308,364,365,366,367,368,369,370],"Diaphragm","Ultrasonography","Pulmonary Funtion","Subacute Hemiplegia","Diaphragm morphology","Respiratory muscle strength","Rehabilitation","2026-03-03",{"date":373,"type":44},"2026-03-05",{"date":375,"type":44},"2026-02-26",{"date":377,"type":22},"2026-09-26",{"name":50,"class":51},{"id":380,"slug":381,"hasResults":12,"nctId":382,"briefTitle":383,"officialTitle":384,"acronym":4,"eligibilityCriteria":385,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":119,"enrollmentInfo":386,"targetDuration":4,"studyType":23,"phases":388,"briefSummary":389,"conditions":390,"keywords":392,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":396,"lastUpdatePostDateStruct":397,"startDateStruct":399,"completionDateStruct":401,"leadSponsor":403,"locationsCount":52},"100620773","the-effect-of-pursed-lip-breathing-exercise-on-anxiety-and-physiological-parameters-post-bronchoscopy-in-patients-with-copd-a-randomized-controlled-trial-100620773","NCT07361978","The Effect of Pursed-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patients With COPD: A Randomized Controlled Trial","The Effect of Purse-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patients With COPD: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients diagnosed with COPD\n* Patients undergoing elective bronchoscopy under sedation\n* Patients aged 18 - 80 years\n* Patients who are fully oriented, conscious, and able to communicate\n\nExclusion Criteria:\n\n* Patients undergoing emergency bronchoscopy\n* Patients with hemodynamic instability prior to the procedure (systolic blood pressure \\\u003C90 mmHg or \\>180 mmHg)\n* Patients with severe hearing or cognitive impairment",{"count":387,"type":22},64,[25],"This randomized controlled trial investigates the effect of Pursed Lip Breathing (PLB) on anxiety levels and physiological parameters in patients with Chronic Obstructive Pulmonary Disease (COPD) following bronchoscopy. While PLB is known to improve oxygenation and ventilation in pulmonary rehabilitation, its specific impact on the immediate recovery period after bronchoscopy is understudied. The study aims to determine if nurse-led PLB intervention significantly improves heart rate, blood pressure, oxygen saturation, and reduces anxiety compared to standard care.",[391],"COPD",[393,394,395,103],"copd","pursed-lip breathing","Nursing care","2026-01-21",{"date":398,"type":44},"2026-01-23",{"date":400,"type":22},"2026-01-28",{"date":402,"type":22},"2026-12-21",{"name":50,"class":51},{"id":405,"slug":406,"hasResults":12,"nctId":407,"briefTitle":408,"officialTitle":409,"acronym":4,"eligibilityCriteria":410,"healthyVolunteers":12,"sex":59,"minAge":411,"maxAge":412,"enrollmentInfo":413,"targetDuration":4,"studyType":23,"phases":415,"briefSummary":416,"conditions":417,"keywords":419,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":424,"lastUpdatePostDateStruct":425,"startDateStruct":427,"completionDateStruct":429,"leadSponsor":431,"locationsCount":52},"100619594","percussive-massage-therapy-using-heat-attachment-in-chronic-low-back-pain-100619594","NCT07346651","Percussive Massage Therapy Using Heat Attachment in Chronic Low Back Pain","The Effect of Percussive Massage Therapy Using a Heat Therapy Attachment on Pain and Disability in Patients With Chronic Low Back Pain","Inclusion Criteria:\n\n* Age 25 to 55 years.\n* Diagnosis of chronic low back pain confirmed by a physician (pain localized to the lumbar region, above the inferior gluteal folds and below the costal margin) with a duration of ≥ 3 months.\n* Baseline pain intensity of 30-80 mm on the Visual Analog Scale (3 cm ≤ VAS ≤ 8 cm).\n\nExclusion Criteria:\n\n* History of, or planned, surgery involving the low back or abdominal region.\n* Malignancy, vertebral fracture, or other serious spinal pathology.\n* Spinal injection or intervention within the past 3 months (e.g., epidural injection, facet joint steroid injection, neuroplasty).\n* Long-term use of analgesic or corticosteroid medications that may affect musculoskeletal symptoms.\n* Diagnosis of radiculopathy or neuropathy (with or without spinal canal stenosis).\n* Cognitive impairment that would preclude providing informed consent.\n* Significant structural spinal deformity (e.g., spondylolisthesis, congenital spinal deformities).\n* Progressive neurological disorder affecting the lower limbs\u002Fspine or inflammatory spinal disease (e.g., axial spondyloarthritis), or cardiovascular instability.\n* Pregnancy.\n* Medical conditions contraindicating exercise participation","25 Years","55 Years",{"count":414,"type":22},48,[25],"Low back pain is a global problem that currently affects many people's participation in daily activities, and its prevalence has been increasing over the years. Exercise is among the most effective treatment approaches for reducing and preventing pain and disability related to low back pain. To enhance the effects of exercise, various adjunctive methods may be needed. Local vibration applications delivered through mechanical devices are offer practical and time-efficient application, which may reduce the physiotherapist's manual workload, while also providing potential benefits for patients with musculoskeletal pain. Therefore, the aim of this study is to investigate the effects of Percussive Massage Therapy (PMT) applied using a heat-therapy attachment on pain, disability, spinal mobility, health-related quality of life, kinesiophobia, and patient satisfaction in individuals with chronic low back pain.\n\nPatients with chronic low back pain who meet the inclusion criteria will be randomly assigned to either the PMT group or the Control group (CG). All participants will receive a conventional rehabilitation program consisting of supervised exercise training and transcutaneous electrical nerve stimulation (TENS) for 2 weeks, 5 days per week, for approximately 45 to 60 minutes per day. The CG will receive only this conventional rehabilitation program. In addition, participants in the PMT group will receive PMT immediately after each conventional rehabilitation session, consisting of an 8-minute application (4 minutes per side) over the paravertebral muscles using a percussive massage therapy device.\n\nOutcome measures will be assessed at baseline and post-treatment (end of week 2). Pain intensity will be evaluated using the Visual Analog Scale (VAS); disability using the Oswestry Disability Index (ODI); spinal flexibility using the finger-to-floor distance test; health-related quality of life using the Short Form-36v2 (SF-36v2); and kinesiophobia using the Tampa Scale for Kinesiophobia (TSK). Treatment satisfaction will be assessed post-treatment using the Global Perceived Effect Scale (GPE), and all data will be recorded on a data collection form.",[418],"Chronic Low Back Pain (CLBP)",[420,421,422,423],"low back pain","percussive massage therapy","vibration","exercise","2026-01-08",{"date":426,"type":44},"2026-01-16",{"date":428,"type":22},"2026-01-12",{"date":430,"type":22},"2026-08",{"name":50,"class":51},{"id":433,"slug":434,"hasResults":12,"nctId":435,"briefTitle":436,"officialTitle":437,"acronym":4,"eligibilityCriteria":438,"healthyVolunteers":89,"sex":59,"minAge":4,"maxAge":4,"enrollmentInfo":439,"targetDuration":4,"studyType":23,"phases":441,"briefSummary":442,"conditions":443,"keywords":449,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":458,"lastUpdatePostDateStruct":459,"startDateStruct":461,"completionDateStruct":463,"leadSponsor":465,"locationsCount":52},"100619513","central-venous-catheter-care-training-for-pediatric-oncology-nurses-100619513","NCT07345598","Central Venous Catheter Care Training for Pediatric Oncology Nurses","Training in Central Venous Catheter Care: Effects on Knowledge and Infection Prevention Behaviors of Pediatric Oncology Nurses","Inclusion Criteria:\n\n* Provided care to a pediatric oncology patient at least once\n* Performed a procedure via a central venous catheter on a pediatric oncology patient\n* Voluntarily signed the informed consent form\n\nExclusion Criteria:\n\n* Not having previously performed a procedure via a central venous catheter",{"count":440,"type":22},30,[25],"The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections. This study was designed to evaluate the effect of training on central venous catheter care (CVCC), provided to nurses caring for pediatric oncology patients, on their knowledge level and infection prevention behaviors. The study aims to determine the effectiveness of an educational program intended to enhance nurses' knowledge and practical skills in preventing CVC-related infections, thereby contributing to evidence-based practices that improve patient safety.",[444,445,446,447,448],"Pediatric Cancer","Pediatric Oncology","Central Venous Catheter","Central Venous Catheter Placement","Central Venous Catheter Exit Site Infection",[450,451,448,452,453,454,455,456,457],"Pediatric Nursing","Central venous catheter placement","Nurse training","hand hygiene","knowledge","infection prevention","clinical education","quasi-experimental study","2026-01-07",{"date":460,"type":44},"2026-01-15",{"date":462,"type":22},"2026-01-22",{"date":464,"type":22},"2026-06-22",{"name":50,"class":51},{"id":467,"slug":468,"hasResults":12,"nctId":469,"briefTitle":470,"officialTitle":471,"acronym":4,"eligibilityCriteria":472,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":119,"enrollmentInfo":473,"targetDuration":4,"studyType":23,"phases":475,"briefSummary":476,"conditions":477,"keywords":481,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":489,"lastUpdatePostDateStruct":490,"startDateStruct":492,"completionDateStruct":494,"leadSponsor":496,"locationsCount":52},"100617191","chewing-gum-flavors-to-reduce-postoperative-nausea-and-vomiting-after-pipac-100617191","NCT07315412","Chewing Gum Flavors to Reduce Postoperative Nausea and Vomiting After PIPAC","Comparative Effectiveness of Ginger-Mint and Cinnamon-Flavored Gum in Preventing Nausea and Vomiting Following Pressurized Intraperitoneal Aerosol Chemotherapy","Inclusion Criteria:\n\n* Adults aged 18 years or older undergoing Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC).\n* Able to communicate, understand study instructions, and provide written informed consent.\n* No known allergy or intolerance to ginger, mint, or cinnamon.\n* Able and willing to chew gum for 15 minutes.\n* Apfel risk score ≥3 for postoperative nausea and vomiting.\n\nExclusion Criteria:\n\n* Postoperative complications requiring intensive care or reoperation.\n* Need for rescue antiemetic medication within the first 2 postoperative hours.\n* History of psychiatric disorder, neurological disease, or cognitive impairment affecting participation.\n* Anatomical or functional limitation preventing chewing (e.g., full dentures, jaw restriction, oral surgery).\n* Known phenylketonuria or metabolic intolerance to chewing gum ingredients.\n* Active chemotherapy, radiotherapy, or immunosuppressive therapy affecting gastrointestinal function.",{"count":474,"type":22},75,[25],"This randomized controlled clinical trial aims to evaluate the effectiveness of chewing gum with different natural flavors in reducing postoperative nausea and vomiting (PONV) following Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC). Adult patients undergoing PIPAC will be randomly assigned to one of three groups: (1) ginger-mint flavored gum, (2) cinnamon flavored gum, or (3) control group with standard postoperative care only. Participants in the intervention arms will chew one piece of gum for 15 minutes in the post-anesthesia care unit (PACU). Nausea intensity (Numeric Rating Scale, 0-10) and the presence of vomiting or retching will be assessed at baseline and every 15 minutes for 2 hours.\n\nThe study hypothesizes that ginger-mint and cinnamon flavored chewing gums, both plant-based and certified vegan, will be effective, non-pharmacological, and safe methods to reduce nausea and vomiting after PIPAC. This research may contribute to enhanced postoperative comfort and faster recovery by supporting the principles of Enhanced Recovery After Surgery (ERAS).",[478,479,480],"Postoperative Nausea and Vomiting (PONV)","Peritoneal Metastases From Colorectal Cancer","Intraperitoneal Chemotherapy",[482,483,484,485,486,487,488],"Chewing gum","ginger","cinnamon","postoperative neusea","vomiting","eras","supportive care","2025-12-23",{"date":491,"type":44},"2026-01-02",{"date":493,"type":22},"2025-12-10",{"date":495,"type":22},"2027-05-30",{"name":50,"class":51},{"id":498,"slug":499,"hasResults":12,"nctId":500,"briefTitle":501,"officialTitle":502,"acronym":503,"eligibilityCriteria":504,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":505,"targetDuration":4,"studyType":23,"phases":507,"briefSummary":508,"conditions":509,"keywords":511,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":516,"lastUpdatePostDateStruct":517,"startDateStruct":519,"completionDateStruct":521,"leadSponsor":523,"locationsCount":52},"100616730","effect-of-a-nurse-led-environmental-stressor-reduction-package-on-perceived-stress-and-sleep-quality-in-intensive-care-unit-patients-100616730","NCT07309406","Effect of a Nurse-Led Environmental Stressor Reduction Package on Perceived Stress and Sleep Quality in Intensive Care Unit Patients","Evaluating the Effects of a Nurse-Led Multicomponent Environmental Intervention on Stress Perception and Sleep Quality in ICU Patients: A Quasi-Experimental Study","ICU-SLEEP","Inclusion Criteria:\n\n* Adults aged 18 years and older\n\nPatients admitted to the intensive care unit (ICU)\n\nAwake and able to communicate (not under sedation or mechanical ventilation)\n\nExpected to remain in the ICU for at least 2 consecutive nights\n\nVoluntary participation with written informed consent\n\nExclusion Criteria:\n\n* Patients under 18 years old\n\nPatients diagnosed with delirium or severe cognitive impairment\n\nPatients with a history of psychiatric illness affecting sleep or stress perception\n\nPatients under continuous sedative or opioid infusion\n\nPatients discharged from the ICU or deceased before completing the intervention period (2-5 nights)",{"count":506,"type":22},68,[25],"This study aims to evaluate the effectiveness of a nurse-led \"Environmental Stressor Reduction Package\" on critically ill patients' perception of environmental stress and their sleep quality in the intensive care unit (ICU).\n\nThe package includes multi-component interventions such as reducing noise levels, adjusting lighting according to circadian rhythm, maintaining thermal comfort, limiting visitor traffic at night, and organizing nursing care to minimize sleep disruption. A structured \"Quiet Night Checklist\" will be used to monitor the implementation of these interventions during night shifts.\n\nThe study will be conducted in the 10-bed anesthesia and reanimation intensive care unit of Ümraniye Training and Research Hospital, İstanbul. Eligible adult patients who are awake, not under sedation, and able to communicate will be recruited. Participants in the intervention group will receive the Environmental Stressor Reduction Package for at least two and up to five consecutive nights, while the control group will continue to receive standard ICU care.\n\nOutcomes will be measured using two validated tools:\n\nThe Intensive Care Unit Environmental Stressor Scale (ICUESS) to assess perceived environmental stress.\n\nThe Richards-Campbell Sleep Questionnaire (RCSQ) to evaluate self-reported sleep quality.\n\nThe findings of this study are expected to contribute to evidence-based nursing interventions in the ICU setting, by improving patients' sleep quality and reducing stressors associated with the intensive care environment.",[510],"Sleep Disturbance",[512,513,514,250,515],"Critical Care Nursing","Environmental Stressors","Intensive Care Unit","Quiet Night Protocol","2025-12-15",{"date":518,"type":44},"2025-12-30",{"date":520,"type":22},"2025-12-29",{"date":522,"type":22},"2026-02-01",{"name":50,"class":51},{"id":525,"slug":526,"hasResults":12,"nctId":527,"briefTitle":528,"officialTitle":529,"acronym":4,"eligibilityCriteria":530,"healthyVolunteers":12,"sex":59,"minAge":411,"maxAge":19,"enrollmentInfo":531,"targetDuration":4,"studyType":23,"phases":533,"briefSummary":534,"conditions":535,"keywords":539,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":544,"lastUpdatePostDateStruct":545,"startDateStruct":547,"completionDateStruct":549,"leadSponsor":551,"locationsCount":52},"100615288","graded-motor-imagery-and-task-oriented-exercise-in-shoulder-impingement-100615288","NCT07290660","Graded Motor Imagery and Task-Oriented Exercise in Shoulder Impingement","Effectiveness of Graded Motor Imagery and Task-Oriented Exercise Training in Shoulder Impingement Syndrome","Inclusion Criteria:Adults aged 25-65 years\n\nDiagnosed with Stage I or Stage II shoulder impingement syndrome by an Orthopedics or Physical Medicine and Rehabilitation physician\n\nPositive Neer and Hawkins tests\n\nUnilateral shoulder pain for at least 3 months\n\nNo participation in any physiotherapy program for shoulder problems within the last year\n\nAbility to cooperate and follow instructions\n\nA score of 24 or above on the Standardized Mini-Mental Test -\n\nExclusion Criteria:\n\nHistory of previous shoulder surgery\n\nLocal corticosteroid injection within the last three months\n\nPresence of uncontrolled neurological, cardiac, or systemic diseases that may interfere with function\n\nCognitive impairments that may affect proper understanding or execution of the motor imagery program\n\nA score below 24 on the Standardized Mini-Mental Test\n\n\\-",{"count":532,"type":22},66,[25],"This study aims to compare the effects of graded motor imagery and task-oriented exercise training in individuals with shoulder impingement syndrome. A total of 66 participants aged 25-65 years will be randomly assigned to one of three groups: conventional physiotherapy, graded motor imagery, or task-oriented exercise training. All groups will receive standardized electrotherapy, while the intervention groups will additionally complete 6-week graded motor imagery or task-oriented exercise programs.\n\nPrimary outcomes include pain intensity, shoulder range of motion, muscle strength, proprioception, functional status, kinesiophobia, laterality recognition, movement imagery ability, and patient satisfaction. Assessments will be conducted before and after the intervention by the same physiotherapist. The study aims to determine whether motor imagery-based or task-oriented rehabilitation provides additional benefits compared with conventional physiotherapy in individuals with shoulder impingement syndrome.",[536,153,537,538],"Shoulder Impingement Syndrome","Motor Imagery Training","Task Oriented Training",[540,541,542,370,543],"Shoulder impingement syndrome","Graded motor imagery","Task-oriented exercise","pain","2025-12-05",{"date":546,"type":44},"2025-12-18",{"date":548,"type":44},"2025-12-01",{"date":550,"type":22},"2026-12-30",{"name":50,"class":51},{"id":553,"slug":554,"hasResults":12,"nctId":555,"briefTitle":556,"officialTitle":557,"acronym":4,"eligibilityCriteria":558,"healthyVolunteers":12,"sex":17,"minAge":60,"maxAge":4,"enrollmentInfo":559,"targetDuration":4,"studyType":23,"phases":561,"briefSummary":562,"conditions":563,"keywords":4,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":566,"lastUpdatePostDateStruct":567,"startDateStruct":569,"completionDateStruct":571,"leadSponsor":572,"locationsCount":4},"100608379","the-effect-of-mobile-application-assisted-nursing-services-on-symptom-control-in-breast-cancer-patients-100608379","NCT07200791","The Effect of Mobile Application-Assisted Nursing Services on Symptom Control in Breast Cancer Patients","Effect of Mobile Application-Supported Nursing Service on Symptom Management in Breast Cancer Patients During Chemotherapy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* 18 yaş ve üzerinde olan,\n* Çalışmaya katılmayı kabul eden,\n* Meme kanseri tanısı alan kadınlar,\n* 4AC-12 Paklitaksel tedavi protokolü uygulana,\n* Okuma yazma bilen ve iletişim problemi olmayan,\n* Akıllı telefonu olan bireyler\n* Akıllı telefonu kullanabilen bireyler\n* Verileri eksiksiz olarak dolduran bireyler\n\nExclusion Criteria:\n\n* Kardiyak problemi olan bireyler\n* Karaciğer ve böbrek yetmezliği olan bireyler\n* Mobil uygulama kullanamayan bireyler\n* Akıllı telefon kullanamayan bireyler\n* Araştırmadan ayrılmak isteyen bireyler\n* Araştırmada çeşitli sebeplerle eksik veri toplanan bireyler",{"count":560,"type":22},74,[25],"Breast cancer is the most common type of cancer in women, accounting for approximately one-quarter of all female cancers in Turkey. Chemotherapy is widely used in treatment, but it also affects healthy cells, leading to numerous side effects such as fatigue, nausea, hair loss, sleep problems, and skin and nail changes. These side effects complicate symptom management and negatively impact patients' self-efficacy and quality of life.\n\nMobile health applications allow patients to track their symptoms, communicate with healthcare professionals, and implement recommended non-pharmacological methods. Literature demonstrates that these applications reduce symptoms, improve quality of life, and enhance self-efficacy.\n\nThis research is a randomized controlled experimental trial designed to evaluate the effect of mobile app-assisted nursing services on symptom management in women diagnosed with breast cancer and undergoing chemotherapy. The research will be conducted in the chemotherapy unit of a training and research hospital in Istanbul.\n\nThe study will consist of two groups: an intervention group and a control group. Randomization will be conducted using a computer-assisted method (random.org). Based on the power analysis, 74 patients will be included in the sample for 85% power at a 95% confidence interval, a significance level of p\\\u003C0.05, and a medium effect size.\n\nInclusion criteria include individuals aged 18 years and older, female, diagnosed with breast cancer, undergoing the 4AC-12 Paclitaxel protocol, owning and using a smartphone, and consenting to participate in the study. Exclusion criteria include patients with cardiac problems, liver or kidney failure, inability to use the mobile app, or providing incomplete data.\n\nStudy data will be collected online via a mobile app. The results of the study will demonstrate the effectiveness of mobile health apps in symptom management, increasing self-efficacy, and improving quality of life.",[564,565],"Symptom Management","Quality of Life","2025-12-02",{"date":568,"type":44},"2025-12-09",{"date":570,"type":22},"2025-12",{"date":430,"type":22},{"name":50,"class":51},{"id":574,"slug":575,"hasResults":12,"nctId":576,"briefTitle":577,"officialTitle":578,"acronym":4,"eligibilityCriteria":579,"healthyVolunteers":12,"sex":59,"minAge":580,"maxAge":412,"enrollmentInfo":581,"targetDuration":4,"studyType":23,"phases":582,"briefSummary":583,"conditions":584,"keywords":586,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":590,"lastUpdatePostDateStruct":591,"startDateStruct":593,"completionDateStruct":595,"leadSponsor":596,"locationsCount":52},"100607799","connective-tissue-massage-and-core-training-in-mechanical-low-back-pain-100607799","NCT07193251","Connective Tissue Massage and Core Training in Mechanical Low Back Pain","The Effects of Connective Tissue Massage Combined With Core Stabilization Exercises on Pain, Functionality, and Endurance in Mechanical Low Back Pain","Inclusion Criteria:\n\n* Participants will be 20-55 years of age.\n* Participants will have a clinician-confirmed diagnosis of mechanical low back pain and will be referred by specialists in Physical Medicine and Rehabilitation.\n* Participants will have adequate cognitive ability to follow assessments and the treatment protocol and will agree to attend supervised sessions (2×\u002Fweek for 8 weeks) and to perform daily home exercises.\n* Participants will provide informed consent prior to any study procedures\n\nExclusion Criteria:\n\n* Participants will be excluded if they have a history of lumbar spine surgery.\n* Participants will be excluded for conditions affecting the lumbar region, including inflammatory arthritis, tumor, or infectious diseases.\n* Participants will be excluded if they present congenital anomalies of the lumbosacral region or secondary orthopedic problems that could interfere with the study.\n* Participants will be excluded if they have neurological disorders (e.g.,Parkinson's disease, Alzheimer's disease, multiple sclerosis) or systemic diseases such as diabetes mellitus.\n* Any medical condition judged by the investigators to preclude safe participation or adherence to the protocol will lead to exclusion.","20 Years",{"count":440,"type":22},[25],"This randomized controlled study will investigate the effects of connective tissue massage combined with core stabilization exercises in patients with mechanical low back pain. Participants will be assigned to two groups: one will receive core stabilization exercises with connective tissue massage, while the other will receive only core stabilization exercises. Pain will be evaluated using the Visual Analog Scale, functionality will be assessed with the Oswestry Disability Index, and endurance will be measured with static and dynamic curl-up, static back endurance, and side bridge tests. Quality of life will be assessed with the SF-36, and instrumental daily living activities will be evaluated with the Lawton \\& Brody Scale. The results will demonstrate whether adding connective tissue massage to core stabilization exercises will provide additional benefits in pain reduction, functional improvement, endurance, and quality of life compared to exercises alone.",[585],"Mechanical Low Back Pain",[587,588,589],"mechanical low back pain","connective tissue massage","core stabilization exercise","2025-09-18",{"date":592,"type":44},"2025-09-25",{"date":594,"type":22},"2025-10-01",{"date":570,"type":22},{"name":50,"class":51},{"id":598,"slug":599,"hasResults":12,"nctId":600,"briefTitle":601,"officialTitle":602,"acronym":4,"eligibilityCriteria":603,"healthyVolunteers":12,"sex":59,"minAge":60,"maxAge":19,"enrollmentInfo":604,"targetDuration":4,"studyType":23,"phases":606,"briefSummary":607,"conditions":608,"keywords":610,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":614,"lastUpdatePostDateStruct":615,"startDateStruct":616,"completionDateStruct":618,"leadSponsor":620,"locationsCount":52},"100604486","effects-of-connective-tissue-massage-and-physical-modalities-combined-with-stabilization-exercises-in-chronic-neck-pain-100604486","NCT07150143","Effects of Connective Tissue Massage and Physical Modalities Combined With Stabilization Exercises in Chronic Neck Pain","Comparative Effects of Connective Tissue Massage and Physical Modalities Added to Cervical and Scapulothoracic Stabilization Exercises on Pain, Function, and Endurance in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Being between 18 and 65 years of age,\n* Having non-specific chronic neck pain localized to the posterior cervical spine between the occipital region and the spinous process of the first thoracic vertebra,\n* Being able to cooperate with the assessments to be performed in the study.\n\nExclusion Criteria:\n\n* Neck pain resulting from trauma within the past 6 months;\n* A history of surgery related to cervical problems;\n* Clinical signs of cervical radiculopathy and\u002For myelopathy;\n* Inflammatory arthritis involving the cervical spine;\n* Tumors or infections of the cervical spine;\n* Vertebrobasilar artery insufficiency;\n* Neurological disorders (such as multiple sclerosis, Parkinson's disease, or syringomyelia);\n* Congenital anomalies affecting the spine; systemic diseases (such as diabetes mellitus);\n* Shoulder pathologies (including tendinitis, bursitis, or capsulitis).",{"count":605,"type":22},27,[25],"This randomized, double-blinded controlled trial aims to investigate the comparative effects of connective tissue massage and physical modalities, when combined with cervical and scapulothoracic stabilization exercises, in individuals with chronic non-specific neck pain. A total of 51 participants aged 18-65 years will be randomly assigned into three groups. Group 1 will perform stabilization exercises alone, Group 2 will receive stabilization exercises plus connective tissue massage, and Group 3 will receive stabilization exercises plus electrotherapy modalities (infrared, continuous ultrasound, and TENS). The interventions will be conducted twice weekly for 8 weeks, and participants will also perform home-based exercises daily. Primary outcomes include pain, disability, and endurance, while secondary outcomes focus on quality of life, cervical range of motion, and scapular function.",[609],"Non-specific Neck Pain",[611,612,588,613],"non-specific neck pain","scapulothoracic stabilization exercises","electrotherapy","2025-09-14",{"date":590,"type":44},{"date":617,"type":44},"2025-09-12",{"date":619,"type":22},"2026-10",{"name":50,"class":51},{"id":622,"slug":623,"hasResults":12,"nctId":624,"briefTitle":625,"officialTitle":626,"acronym":627,"eligibilityCriteria":628,"healthyVolunteers":89,"sex":59,"minAge":629,"maxAge":630,"enrollmentInfo":631,"targetDuration":4,"studyType":23,"phases":632,"briefSummary":633,"conditions":634,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":641,"lastUpdatePostDateStruct":642,"startDateStruct":644,"completionDateStruct":646,"leadSponsor":648,"locationsCount":52},"100596434","effect-of-developmental-care-on-comfort-growth-and-oral-feeding-transition-in-preterm-infants-100596434","NCT07045402","Effect of Developmental Care on Comfort, Growth, and Oral Feeding Transition in Preterm Infants","The Effect of Kangaroo Care and Maternal Voice on Comfort, Anthropometric Measurements, and Transition to Oral Feeding in Preterm Infants","KCareInfant","Inclusion Criteria:\n\n1. Infants with a gestational age between 30-34 weeks.\n2. The mother's ability to read and write.\n3. The infant must be fully enterally fed at the time of enrollment in the study.\n4. Infants who are being fed via orogastric tube at the time of enrollment.\n5. Infants whose mothers agree to engage in skin-to-skin contact for 1 hour, five sessions per week, with auditory stimulation (storytelling) for 15 minutes will be included in the study.\n6. Infants whose mothers cannot participate in the study (due to health issues or other reasons) or refuse kangaroo care will be placed in the control group, where routine service care will be applied.\n\nExclusion Criteria:\n\n1. Presence of a congenital anomaly or genetic disease.\n2. Requirement of ventilator support.\n3. Infants receiving antibiotics for sepsis or suspected sepsis.\n4. Administration of sedative treatment.\n5. Having an intracranial hemorrhage greater than grade II.\n6. The mother having a physical condition that prevents skin-to-skin contact.\n7. The mother using substances or alcohol.","30 Weeks","34 Weeks",{"count":506,"type":22},[25],"This randomized controlled study aims to evaluate the effects of kangaroo care combined with maternal voice and fetal positioning on the comfort, growth, and transition to full oral feeding in preterm infants aged 30 to 34 weeks gestation. After ethical approval, eligible infants in the neonatal clinic will be randomly assigned to either the intervention group receiving kangaroo care, maternal voice, and fetal positioning, or a control group receiving only fetal positioning in the incubator. The intervention involves daily one-hour kangaroo care sessions with maternal storytelling, followed by positioning in the lateral fetal posture, continuing at least five days per week until infants achieve full oral feeding. Infant comfort will be assessed regularly using the Neonatal Comfort Behavior Scale before feeding, immediately after kangaroo care, and after fetal positioning. Growth parameters, including weight, length, and head circumference, will be measured and recorded on kangaroo care days. The control group will receive routine fetal positioning without kangaroo care, with identical measurements taken. The study aims to determine whether kangaroo care combined with maternal voice and fetal positioning improves infant comfort, supports growth, and facilitates the transition to full oral feeding in preterm newborns.",[635,636,637,638,639,640],"Infant, Premature","Kangaroo Mother Care","Comfort","Feeding","Oral Feeding Performance","Facilitated Tucking","2025-09-03",{"date":643,"type":44},"2025-09-04",{"date":645,"type":44},"2025-02-10",{"date":647,"type":22},"2026-03-10",{"name":50,"class":51},{"id":650,"slug":651,"hasResults":12,"nctId":652,"briefTitle":653,"officialTitle":653,"acronym":4,"eligibilityCriteria":654,"healthyVolunteers":12,"sex":59,"minAge":655,"maxAge":4,"enrollmentInfo":656,"targetDuration":4,"studyType":23,"phases":657,"briefSummary":658,"conditions":659,"keywords":661,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":665,"lastUpdatePostDateStruct":666,"startDateStruct":668,"completionDateStruct":670,"leadSponsor":672,"locationsCount":52},"100605504","effect-of-art-therapy-on-cognitive-and-hand-functions-of-alzheimers-patients-100605504","NCT07163377","Effect of Art Therapy on Cognitive and Hand Functions of Alzheimer's Patients","Inclusion Criteria:\n\n* Being 60 years of age or older\n* Having a diagnosis of mild or moderate Alzheimer's disease\n* Possessing the physical and cognitive capacity to participate in art therapy interventions\n* Providing informed consent\n\nExclusion Criteria:\n\n* Being in the severe stage of Alzheimer's disease\n* Having a history of severe psychiatric disorders such as schizophrenia or major depression\n* Having a physical disability that prevents the use of the upper extremities\n* Being unable to participate in the intervention due to visual or hearing impairments","60 Years",{"count":275,"type":22},[25],"This randomized controlled trial aims to investigate the effects of art therapy on cognitive functions and hand functions in individuals with Alzheimer's disease. Alzheimer's disease is a progressive neurodegenerative disorder characterized by decline in memory, executive functions, and daily living activities. In addition, fine motor skills and hand-eye coordination are significantly impaired, limiting independence in daily tasks.\n\nArt therapy is a non-pharmacological, low-cost, and feasible intervention that involves creative activities such as mandala painting, collage, clay modeling, and drawing. It has been shown to support cognitive performance, emotional well-being, and motor coordination by stimulating neuroplasticity. However, evidence focusing specifically on its impact on hand function in Alzheimer's patients remains limited.\n\nIn this study, 50 participants aged 60 years and older with mild to moderate Alzheimer's disease will be randomly assigned to an intervention group or a control group. The intervention group will attend art therapy sessions twice a week for 8 weeks (60 minutes per session), while the control group will receive no intervention. Cognitive functions will be assessed using the Mini-Mental State Examination (MMSE), and hand functions will be evaluated with the Nine Hole Peg Test (NHPT) and surface electromyography (sEMG) of forearm muscles.\n\nThe results of this study are expected to provide valuable evidence on the role of art therapy in supporting both cognitive and motor rehabilitation in Alzheimer's disease, potentially contributing to improved daily living independence and quality of life.",[660],"Alzheimer Disease",[662,663,664],"Alzheimer","Art therapy","Cognitive Function","2025-09-01",{"date":667,"type":44},"2025-09-09",{"date":669,"type":22},"2025-09",{"date":671,"type":22},"2026-01",{"name":50,"class":51},{"id":674,"slug":675,"hasResults":12,"nctId":676,"briefTitle":677,"officialTitle":677,"acronym":4,"eligibilityCriteria":678,"healthyVolunteers":12,"sex":59,"minAge":655,"maxAge":4,"enrollmentInfo":679,"targetDuration":4,"studyType":23,"phases":681,"briefSummary":682,"conditions":683,"keywords":684,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":665,"lastUpdatePostDateStruct":686,"startDateStruct":687,"completionDateStruct":688,"leadSponsor":690,"locationsCount":4},"100605478","the-effect-of-dual-task-training-on-cognitive-in-alzheimers-disease-100605478","NCT07163039","The Effect of Dual Task Training on Cognitive in Alzheimer's Disease","Inclusion Criteria:\n\n* Age ≥ 60 years\n* Diagnosed with mild-stage Alzheimer's disease (According to DSM-5 or NINCDS-ADRDA criteria)\n* MoCA score between 10-25 (Indicating sufficient cognitive capacity for dual-task training)\n* Ability to walk independently or with minimal assistance\n* Adequate hearing and vision to enable communication\n* Physical and mental capacity to participate in the dual-task training protocol\n* Provision of written informed consent (signed informed consent form)\n\nExclusion Criteria:\n\n* Diagnosis of advanced-stage Alzheimer's disease (MoCA \\\u003C 10)\n* Presence of additional neurological disorders affecting the motor system (e.g. Parkinson's disease, stroke, multiple sclerosis)\n* Severe hearing or vision impairment (inability to respond to visual or auditory stimuli)\n* History of psychiatric disorders (e.g., major depression, schizophrenia)\n* Orthopedic or cardiopulmonary conditions that would prevent participation in dual-task training\n* Participation in another cognitive or physical rehabilitation program within the last 3 months\n* Individuals with unstable cognitive status due to recent medication changes",{"count":680,"type":22},60,[25],"This randomized controlled clinical trial aims to evaluate the effectiveness of dual-task training on cognitive functions in patients with Alzheimer's disease. Participants will be randomly assigned to either a dual-task training group or a conventional exercise group. The intervention will last 8 weeks, with three supervised sessions per week. Cognitive performance, mobility, balance, and quality of life will be assessed before and after the intervention.",[660],[662,685],"Dual-Task Training",{"date":667,"type":44},{"date":669,"type":22},{"date":689,"type":22},"2026-05",{"name":50,"class":51},""]