[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fisher and Paykel Healthcare\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":250},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,44,73,96,119,142,162,181,205,230],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100610040","closed-loop-oxygen-control-in-chronic-obstructive-pulmonary-disease-copd-patients-treated-with-nasal-high-flow-in-the-hospital-100610040",false,"NCT07222410","Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital","Closed Loop Oxygen Control in COPD Patients Treated With Nasal High Flow in the Hospital","Inclusion Criteria:\n\n* Has cognitive ability to provide informed consent\n* Aged 22 years or older\n* Hospitalized with hypoxemia\u002Frespiratory distress\n* Diagnosis of COPD\n* Candidate for\u002Fcurrently prescribed nasal high flow (flow rate of at least 25 L\u002Fmin) with supplemental oxygen, as assessed by the investigator\n* Expected duration of oxygen and nasal high flow therapy \\>24 hours (not necessarily continuous)\n\nExclusion Criteria:\n\n* Receiving Non Invasive Ventilation (NIV) or indicated for NIV as per European Respiratory Society \u002FAmerican Thoracic Society guidelines\n* Hemodynamic instability (systolic blood pressure \\\u003C90mmHg or requirement for vasopressor or inotropic support)\n* Patient receiving end of life care\n* Nasal or facial conditions precluding use of nasal high flow\n* Pregnancy or breastfeeding\n* Cognitive impairment or impaired consciousness precluding informed consent\n* Unsuitable for adhesive finger pulse oximetry, as assessed by the investigator\n* Any other condition which, at the investigator's discretion, is believed to present a safety risk to the patient if included\n* The presence of any active comorbidities that affect the patient's condition importantly in the next 30 days, as assessed by the investigator\n* Has already participated in this clinical trial","ALL","22 Years",{"count":19,"type":20},70,"ESTIMATED","INTERVENTIONAL",[23],"NA","The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with hypoxemia\u002Frespiratory distress.",[26],"COPD",[26,28,29,30],"closed loop oxygen control","hypoxemia","nasal high flow","RECRUITING","2026-06-21",{"date":34,"type":35},"2026-06-23","ACTUAL",{"date":37,"type":35},"2026-01-07",{"date":39,"type":20},"2027-11",{"name":41,"class":42},"Fisher and Paykel Healthcare","INDUSTRY",4,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100630217","vela-generation-ii-usability-and-performance-of-a-non-invasive-ventilation-mask-100630217","NCT07484802","Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask.","Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask. A Prospective Self-Controlled Study.","Inclusion Criteria:\n\n* Adults that are stable on prescribed NIV\n* Able to receive NIV therapy on a sub-nasal mask\n* Are 21 years old or older\n\nExclusion Criteria:\n\n* Contraindicated for NIV\n* NIV is likely to fail and\u002For intubation be required, at the doctor's discretion\n* CPAP or bilevel pressure of ≥ 30 cmH2O required\n* Do not fit the investigation mask or the standard mask\n* Pregnancy (tested under standard care)\n* Unable to tolerate NIV for the duration of the investigation\n* Unable to understand the consent process","21 Years",{"count":53,"type":20},60,[23],"Study Overview The goal of this clinical trial is to learn whether an improved non invasive ventilation mask with airway washout can reduce how often people need to breathe and perform as well as standard NIV masks when used with different ventilators, in people receiving NIV therapy for respiratory distress or respiratory insufficiency.\n\nThe main question(s) it aims to answer are:\n\n* Does the new mask reduce breathing rate compared with a standard NIV mask?\n* Does the ventilator perform as expected when used with the new mask, including pressure delivery and leak?\n* Do clinicians and participants find the new mask fits and functions well?\n\nThree iterations of the new mask (vented, non-vented, dual limb) will be compared to standard of care to see if the mask reduces the need to breathe and performs consistently across ventilators compared with usual NIV masks.\n\n\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_\\_ What Participants Will Do Participants will wear two different NIV masks, each for one hour, during a single study session lasting approximately 2.5 hours.\n\nParticipants will be asked to:\n\n* Wear a small, stick on carbon dioxide (CO₂) sensor on the skin.\n* Use their usual NIV mask for one hour while ventilator data are collected.\n* Switch to the investigational mask for one hour while ventilator data are collected.\n* Choose whether to return to their original mask or remain on the investigational mask after the study period.\n* Caregiver opinion on the mask will be collected.\n\nParticipants may also choose (optional):\n\n* To have three small blood samples taken (These samples are optional, and participants can still take part in the study if they decline them.)\n\n  * One when they agree to take part in the study\n  * One when the investigational mask is fitted\n  * One after wearing the investigational mask for one hour\n* To provide feedback on how the two masks felt and performed.\n\nDuring the study, researchers will collect data from the ventilator, including:\n\n* Breathing rate and depth\n* NIV pressure settings\n* Amount of air leak Research staff will also complete a short form assessing how well the mask fit and functioned. Participants will remain in the study until the investigational mask is removed.",[57,58],"Respiratory Insufficiency","Respiratory Failure",[60,61,62,63],"Airway washout","Fisher and Paykel healthcare","optiNIV","vela gen 2","NOT_YET_RECRUITING","2026-03-18",{"date":67,"type":35},"2026-03-20",{"date":69,"type":20},"2026-07-01",{"date":71,"type":20},"2027-12-31",{"name":41,"class":42},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},"100628947","nasal-airflow-in-post-operative-patients-100628947","NCT07468266","Nasal Airflow in Post-operative Patients","Impacts of F&P Tui on Cortical Activity in Invasively Ventilated Post-operative Patients","Inclusion Criteria:\n\n* Adults \\>18 years of age\n* Receiving sedation via propofol and fentanyl\n* Undergoing surgical procedure with planned post-operative invasive ventilation\n\nExclusion Criteria:\n\n* Pre-existing neurological injury or condition","18 Years",{"count":82,"type":20},12,[23],"The goal of this investigation is to examine the effect of nasal airflow in invasively ventilated adult patients following planned surgery. The main questions it aims to answer are:\n\n* Does the investigational device produce an effect measured by EEG?\n* Are there differences in effect with modified airflow states?",[86],"Invasive Ventilation","2026-03-09",{"date":89,"type":35},"2026-03-12",{"date":91,"type":20},"2026-03",{"date":93,"type":20},"2027-02",{"name":41,"class":42},1,{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":103,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":21,"phases":105,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":116,"leadSponsor":118,"locationsCount":4},"100628598","the-effect-of-home-and-hospital-mask-designs-on-respiratory-variables-in-healthy-volunteers-100628598","NCT07463716","The Effect of Home and Hospital Mask Designs on Respiratory Variables in Healthy Volunteers","The Effect of Home and Hospital Mask Designs on Respiratory Variables in Healthy Volunteers: A Pilot Clinical Investigation","Inclusion Criteria:\n\n* Aged 18 years or over\n* Able to give informed consent\n\nExclusion Criteria:\n\n* Unable to tolerate non-invasive ventilation (NIV)\n* Unable to adequately fit an NIV mask\n* Claustrophobia while using NIV\n* Symptoms of cold or flu (including COVID-19) in previous twenty-four hours\n* Chronic Rhinitis or self-reported history of upper airway obstruction\n* Pneumothorax or history of previous pneumothorax\n* Employee in the NIV team at Fisher \\& Paykel Healthcare",true,{"count":5,"type":20},[23],"The goal of this randomized cross-over study is to investigate whether the design of non-invasive ventilation (NIV) mask impacts respiratory variables in healthy volunteers on NIV therapy. The main questions it aims to answer are:\n\n* To assess if mask design impacts the ventilatory ratio in healthy volunteers.\n* To assess if mask design impacts transcutaneous CO2, respiratory rate, and tidal volume in healthy volunteers.\n\nParticipants will attend five study visits:\n\n* Visit 1. Participants will be fitted to use non-invasive ventilation briefly to acclimatize them to using the therapy.\n* Visit 2. Participants will receive NIV with one of four masks. They will be asked to breathe through their mouth or through their nose, with a break from NIV in between the two sessions of NIV.\n* Visits 3-5. Participants will receive NIV with one of the other three masks, repeating Visit 2.",[108],"Healthy Volunteers",[110,111],"Noninvasive ventilation","Pulmonary","2026-03-05",{"date":114,"type":35},"2026-03-11",{"date":91,"type":20},{"date":117,"type":20},"2026-06",{"name":41,"class":42},{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":21,"phases":128,"briefSummary":129,"conditions":130,"keywords":132,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":141,"locationsCount":4},"100588324","niv-with-airway-washout-for-dual-limb-ventilation-improvement-in-minute-ventilation-100588324","NCT06939920","NIV With Airway Washout for Dual Limb Ventilation: Improvement in Minute Ventilation","Inclusion Criteria:\n\n* Adults admitted to the ICU prescribed NIV and stable\n* Able to receive therapy on a sub-nasal (under-the-nose) mask\n* Are 18 years old or older\n\nExclusion Criteria:\n\n* Contraindicated for NIV\n* NIV is likely to fail and\u002For intubation be required, at the medical staff's discretion\n* Bilevel pressure of ≥ 30 cmH2O required\n* Do not fit the investigational mask or the standard mask\n* Pregnancy (tested under standard care)\n* Unable to tolerate NIV for the duration of the investigation\n* Agitated\n* Unable to understand the consent process","90 Years",{"count":127,"type":20},20,[23],"This is a prospective, non-randomized, non-blinded, crossover feasibility investigation to assess the safety, usability, and efficacy of the investigational mask in the hospital environment. Eligible patients that are stable in NIV and able to give informed consent will be approached and if they consent the patient will be included in the study. If potential participants decline, normal hospital care will be continued. The enrolled participant will receive NIV on the commercially available Visairo mask for one hour during which their ventilatory parameters will be logged. Then the participant will be switched to the investigational mask for another hour. The ventilator data will be collected for these two hours. At the end of the intervention the participant will be reverted to their original mask. The medical staff will be asked to fill out the case report form pertaining to the function and usability of the investigational mask compared to the conventional mask.",[131],"Respiratory Failure Requiring Non Invasive Ventilation",[133,134,60],"Non-invasive ventilation","OptiNIV","2025-05-19",{"date":137,"type":35},"2025-05-22",{"date":139,"type":20},"2025-07-01",{"date":69,"type":20},{"name":41,"class":42},{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":148,"targetDuration":4,"studyType":21,"phases":149,"briefSummary":150,"conditions":151,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":95},"100590835","the-effect-of-mask-design-on-ventilation-parameters-in-copd-and-ohs-patients-on-long-term-home-non-invasive-ventilation-an-experimental-study-100590835","NCT06972589","The Effect of Mask Design on Ventilation Parameters in COPD and OHS Patients on Long-term Home Non-invasive Ventilation. An Experimental Study.","Inclusion Criteria:\n\n* Age over 18 years\n* Prescribed nocturnal NIV for COPD or OHS\n* Able to complete an overnight sleep study\n* Comfortable to sleep on a standard double bed\n* Capacity to complete informed consent\n\nExclusion Criteria:\n\n* Uncontrolled sleep apnea (Apnea-hypopnea index (AHI) over 15 events\u002Fhour off personal NIV device data)\n* Prescribed IPAP above 25 cmH2O\n* Allergic to adhesive of the sensors\n* Self-reported cold\u002Fflu symptoms",{"count":127,"type":20},[23],"Chronic obstructive pulmonary disease (COPD) and obesity hypoventilation syndrome (OHS) are respiratory conditions that disrupt normal breathing. Positive airway pressure, specifically Non-Invasive Ventilation (NIV) delivers positive pressures via an interface such as a face mask and has been shown to improve breathing and reduce symptoms in patients with these conditions. Regular use of NIV can lead to better symptom management, improved quality of life, and reduced use of healthcare resources. However, poor performance of the NIV mask and poor comfort can make NIV therapy harder to tolerate. This study will assess if a new mask helps to improve the breathing of people on NIV and normalize blood gases.",[152,153],"COPD (Chronic Obstructive Pulmonary Disease)","Obesity Hypoventilation Syndrome (OHS)","2025-05-07",{"date":156,"type":35},"2025-05-15",{"date":158,"type":20},"2025-05",{"date":160,"type":20},"2026-04",{"name":41,"class":42},{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":169,"targetDuration":4,"studyType":21,"phases":171,"briefSummary":172,"conditions":173,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":95},"100568519","assessment-of-breathing-pattern-during-niv-100568519","NCT06682286","Assessment of Breathing Pattern During NIV","Breathing Route in COPD and OHS Patients on Long-term Home Non-invasive Ventilation: An Experimental Study","Inclusion Criteria:\n\n* Age over 18 years\n* Prescribed nocturnal NIV for COPD or OHS\n* Able to complete an overnight sleep study\n* Comfortable to sleep on a standard double bed\n* Capacity to complete informed consent\n\nExclusion Criteria:\n\n* Uncontrolled sleep apnea (Apnea-hypopnea index (AHI) over 15 events\u002Fhour off personal NIV device data)\n* Prescribed IPAP above 25 cmH2O\n* Self-reported pregnancy\n* Allergic to adhesive of the sensors\n* Self-reported cold\u002Fflu symptoms",{"count":170,"type":20},40,[23],"COPD and OHS are respiratory conditions that disrupt normal breathing. Positive airway pressure, specifically Non-Invasive Ventilation (NIV), has been shown to improve breathing and reduce symptoms in patients with these conditions. Regular use of NIV can lead to better symptom management, improved quality of life, and reduced use of healthcare resources. The type of mask used for breathing support can greatly affect a patient's comfort and willingness to use it. For conditions like Obstructive Sleep Apnea (OSA), which is a physical blockage of the airway caused by the relaxation of the muscles of the throat, nasal masks are often used because they are comfortable and work well. But for breathing support in the hospital, full face masks are typically used because patients are having significant trouble breathing and tend to breathe through their mouth.\n\nHowever, it's important to note that we don't yet fully understand the best way to provide breathing support for long-term NIV users, like COPD and OHS patients. The understanding of breathing route is currently only established for OSA. However, conditions like COPD affect the lungs and the overall system used for breathing, which is different from the throat blockage seen in OSA. So, the assumptions we make based on conditions like OSA may not apply to these other conditions. More research is needed to understand this better.",[152,153],{"date":175,"type":35},"2025-05-11",{"date":177,"type":35},"2025-01-24",{"date":179,"type":20},"2025-09",{"name":41,"class":42},{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":187,"targetDuration":4,"studyType":21,"phases":189,"briefSummary":190,"conditions":191,"keywords":194,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":204},"100516666","pilot-physiological-evaluation-of-an-investigational-mask-with-expiratory-washout-100516666","NCT06007495","Pilot Physiological Evaluation of an Investigational Mask with Expiratory Washout.","Inclusion Criteria:\n\n* No indication of intubation upon evaluation by physician in the next 2 hours\n* Fits the investigational mask\n\nSpecific for hypercapnic patients 1 of the following criteria\n\n* Patients hospitalized with acute respiratory failure (ARF) stabilized and tolerating NIV or;\n* Patient admitted to hospital with ARF with one criteria for NIV among the following:\n\n  * Acute hypercapnic respiratory failure with hypercapnia and acidosis (Partial pressure of arterial carbon dioxide (PaCO2) \\> 45 millimeters of mercury (mmHg) and pH \\\u003C 7.38) or\n  * Post-extubation period within 48 hours, in patients with high risk of re-intubation\n\nSpecific for hypoxemic patients\n\n1 of the following criteria\n\n* Hypoxemic respiratory failure without hypercapnia requiring nasal high flow or;\n* Hypoxemic respiratory failure without hypercapnia requiring NIV or;\n* Conventional oxygen therapy (COT) \\> 6 liters per minute (L\u002Fmin) with peripheral oxygen saturation (SpO2) \\\u003C 92%\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Inability to provide informed consent\n* Infectious isolation\n* Facial deformity, burns or morphology that prevents adequate mask placement\n* Claustrophobia\n* Nausea\n* Presence of nasogastric tube\n* Pneumothorax\n* Confusion or loss of consciousness\n* Severe upper gastro-intestinal bleeding\n* Any other condition, which at the investigators discretion, is believed may present a safety risk or impact the feasibility of the study or study results",{"count":188,"type":20},32,[23],"The goal of this pilot randomized cross-over study is to compare the effect of a full-face mask with expiratory washout to a conventional full face mask on non-invasive ventilation (NIV) in patients with acute hypercapnic, and acute hypoxemic, respiratory failure. The main questions it aims to answer are:\n\n* Does a mask with expiratory washout improve minute ventilation in patients using non-invasive ventilation compared with a conventional single-limb NIV mask\n* How does a mask with expiratory washout affect respiratory variables compared with a dual-limb NIV mask.\n\nParticipants already prescribed NIV will undergo 3 arms of the investigation in a randomized order:\n\n* Single-limb NIV with investigation mask (with expiratory washout)\n* Single-limb NIV with conventional mask\n* Dual-limb NIV with conventional mask",[192,193],"Acute Hypercapnic Respiratory Failure","Acute Hypoxemic Respiratory Failure",[195],"Non-invasive Ventilation","2025-03-12",{"date":198,"type":35},"2025-03-14",{"date":200,"type":35},"2024-05-06",{"date":202,"type":20},"2025-12",{"name":41,"class":42},2,{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":103,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":211,"targetDuration":4,"studyType":21,"phases":213,"briefSummary":214,"conditions":215,"keywords":217,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":95},"100572847","the-inflate-study-defining-the-soft-palate-in-the-upper-airway-flow-pathway-100572847","NCT06738589","The Inflate Study; Defining the Soft Palate in the Upper Airway Flow Pathway","Inclusion Criteria:\n\n* Healthy adults aged 18+\n* Willing and able to consent to the study\n\nExclusion Criteria:\n\n* Contraindications for MRI (such as metal implants)\n* Contraindications for NIV (such as pneumothorax)\n* No history of lung or upper airway disease\n* Claustrophobia\n* Symptoms of a cold, flu, or significant congestion, within the last 3 days\n* Self-reported confirmed or suspected pregnancy\n* Palatal abnormalities or previous upper airway surgery (such as cleft palate and\u002For UPPP)\n* Prior major head or neck surgery with or without irradiation (such as radiotherapy of cutaneous cancers, robotic surgery for an oropharyngeal cancer)",{"count":212,"type":20},50,[23],"The goal of this clinical trial is to understand the impact of the size and shape of the soft palate on gas airflow in the upper airway in healthy volunteers. Utilizing Magnetic Resonance Imaging (MRI), this study aims to investigate:\n\n* How does soft palate anatomy change in different body positions?\n* What is the impact of positive pressure therapy, in the form of non-invasive ventilation (NIV) on soft palate anatomy? Researchers will compare MRI data without positive pressure to with positive pressure imaging to see if the addition of positive pressure impacts the size and shape of the soft palate.\n\nResearchers will also utilize measures of upper airway resistance to assess the impact of soft palate anatomy of airflow dynamics.\n\nParticipants will be asked to:\n\n* Lie inside an MRI scanner for up to 90 minutes (including breaks), in different body positions\n* Undergo NIV therapy for 5-10 minutes while breathing normally inside an MRI scanner\n* Have their upper airway resistance measured, in different body positions",[216,195],"Focus of the Study is the Anatomy of the Soft Palate",[218,219,220,221],"Soft Palate","MRI","NIV","Airway","2025-03-03",{"date":224,"type":35},"2025-03-05",{"date":226,"type":20},"2025-03-25",{"date":228,"type":20},"2027-08-01",{"name":41,"class":42},{"id":231,"slug":232,"hasResults":11,"nctId":233,"briefTitle":234,"officialTitle":234,"acronym":4,"eligibilityCriteria":235,"healthyVolunteers":11,"sex":16,"minAge":236,"maxAge":4,"enrollmentInfo":237,"targetDuration":4,"studyType":21,"phases":238,"briefSummary":239,"conditions":240,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":95},"100471697","oxygen-wound-therapy-feasibility-study-100471697","NCT05422248","Oxygen Wound Therapy Feasibility Study","Inclusion Criteria:\n\n* Patients with hard to heal lower leg wounds as determined by the treating clinician.\n* Patient has a wound area greater than the area of the interface\n* Aged 16 years and over\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Lower limb wounds with bone or tendon exposed\n* Infected wounds which require treatment with antibiotics\n* Wounds with critical bioburden requiring a medicated dressing\n* Wounds that require dressing changes more than every second day, for example high exudating wounds\n* Wounds with slough covering more than 30% of the wound surface","16 Years",{"count":5,"type":20},[23],"Determine the feasibility of using a new topical oxygen therapy device to treat hard to heal lower leg wounds.",[241],"Chronic Leg Ulcer","2023-09-11",{"date":244,"type":35},"2023-09-13",{"date":246,"type":35},"2022-12-01",{"date":248,"type":20},"2026-08-01",{"name":41,"class":42},""]