[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Florida Atlantic University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":175},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,43,66,93,123,143],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100639341","exploring-the-feasibility-of-an-exercise-and-noninvasive-brain-stimulation-intervention-in-breast-cancer-survivors-100639341",false,"NCT07587957","Exploring the Feasibility of an Exercise and Noninvasive Brain Stimulation Intervention in Breast Cancer Survivors","Inclusion Criteria:\n\n* Breast cancer survivors (≥18 years) will be eligible to participate if the following inclusion criteria is met:\n* Diagnosed non-metastatic breast cancer (stages 0-3)\n* Completed primary breast cancer treatment (surgery, chemotherapy, radiation) for at least 3 months\n* Self-reported cognitive impairment after cancer treatment\n\nExclusion Criteria:\n\n* Current participation in aerobic exercise for ≥60 min\u002Fwk\n* Contraindication or impairment that precludes the potential participant from exercise as defined by the American College of Sports Medicine\n* The presence of serious medical illnesses, metal implants, previous brain trauma, epilepsy or history of seizures, previous surgery to the head or spinal cord, or skin problems at the forehead area where the tACS electrodes will be applied\n* Uncontrolled cardiovascular disease\n* Functional impairments or physical condition that would make exercise unsafe\n* Metastatic cancer or diagnosis of a different cancer (excluding melanoma) within the past 5 years\n* Contraindication to exercise a defined by the American College of Sports Medicine","ALL","18 Years",{"count":18,"type":19},40,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this study is to assess the feasibility of a 4-week intervention combining exercise and transcranial alternating current stimulation (Ex+tACS) in breast cancer survivors who report experiencing cancer-related cognitive impairment. Feasibility will be assessed by measuring participant retention, adherence, satisfaction with the intervention, and safety. The researchers will also examine pre-to-post intervention changes in attention, executive function, working memory, perceived cognitive function, and physical function before, after, and four weeks post intervention completion in the Ex+tACS group compared to a control group who will receive exercise and a placebo tACS condition (CON).",[25],"Breast Cancer",[25,27,28,29],"Cancer-related cognitive impairment","Non-invasive brain stimulation","Exercise","RECRUITING","2026-05-07",{"date":33,"type":34},"2026-05-14","ACTUAL",{"date":36,"type":34},"2026-01-07",{"date":38,"type":19},"2027-01-01",{"name":40,"class":41},"Florida Atlantic University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":20,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":42},"100634649","impact-of-dog-adoption-and-training-in-veterans-with-post-traumatic-stress-symptoms-andor-other-mental-health-conditions-100634649","NCT07542431","Impact of Dog Adoption and Training in Veterans With Post-traumatic Stress Symptoms and\u002For Other Mental Health Conditions","Assessment of Biopsychosocial Indicators Linked to Canine Intervention Treatment Response in Veterans With Post-traumatic Stress Symptoms and\u002For Other Mental Health Conditions","VCRM","Inclusion Criteria:\n\n* Military veteran with self-reported posttraumatic stress symptoms and\u002For other mental health conditions\n* Over 18 years of age\n* Applied and approved to adopt a shelter dog for training through the Humane Society of Broward County in Fort Lauderdale, Florida\n* English speaker (written and spoken)\n* Home internet access via tablet, computer or smartphone.\n\nExclusion Criteria:\n\n* Fear of dogs\n* Allergies to pet dander\n* Uncorrected hearing or visual impairment.",{"count":52,"type":19},120,[22],"The goal of this single-arm study is to learn if a dog adoption and training program can treat, prevent in \\[describe participant population\u002Fprimary condition; could include any of the following: sex\u002Fgender, age groups, healthy volunteers\\]. The main questions it aims to answer are:\n\n* Does the dog adoption and training program decrease posttraumatic stress symptoms in veterans with self-reported posttraumatic stress symptoms?\n* Does the dog adoption and training program decrease stress and improve psychosocial health in veterans with self-reported posttraumatic stress symptoms?\n* Does the dog adoption and training program decrease inflammation, increase oxytocin, and change the structure and resting-state function of specific brain regions in veterans with self-reported posttraumatic stress symptoms?\n\nParticipants will:\n\n* Attend eight one-hour professional dog training sessions within a 10-week period.\n* Visit the clinical research unit four times during the study for data collection.",[56,57],"Posttraumatic Stress Symptoms","Mental Health Conditions","2026-04-21",{"date":60,"type":34},"2026-04-24",{"date":62,"type":34},"2026-02-09",{"date":64,"type":19},"2030-12",{"name":40,"class":41},{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":15,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":42},"100602745","brain-nad-in-alzheimers-disease-100602745","NCT07127510","Brain NAD in Alzheimer's Disease","Measurement of Brain NAD Levels in Alzheimer's Patients and Control Subjects by 1H-MRS","ALZNAD","Inclusion Criteria:\n\n* Participants are able to come to the Florida Atlantic University Clinical Research Unit, are verbal and ambulatory.\n* Age 65 to 80 included.\n* People with Alzheimer's disease (AD): AD diagnosis established by the person's physician according to the following criteria: clinical diagnosis AND either positive amyloid PET-scan or FDA-approved positive CSF or blood test.\n\nExclusion Criteria:\n\n* Under the age of 65 or over the age of 80.\n* Advanced dementia such that the person would require sedation for undergoing an MRI scan.\n* Receiving anti-amyloid intravenous treatments Leqembi or Kinsula.\n* Having an MRI-incompatible pacemaker or other MRI-incompatible hardware (e.g. comprising a metallic part).\n* Having a history of seizures.\n* Working at night.\n* Having cancer or having been diagnosed with cancer within the last 5 years (excluding superficial squameous or basal cell cancer).\n* People with no AD: MoCA test result lower than 26.",true,"65 Years","80 Years",{"count":78,"type":19},20,"OBSERVATIONAL","The goal of this observational study is to learn about the levels of nicotinamide adenine dinucleotide (NAD) in the brains of people with Alzheimer's disease. The study aims to determine if brain NAD levels are lower in people with Alzheimer's disease compared with people of the same age group who do not have Alzheimer's disease.\n\nParticipants with or without Alzheimer's disease will have a brain imaging session where NAD will be measured using magnetic resonance spectroscopy (MRS). Eight months later, they will have a second, similar, brain imaging session.",[82],"Alzheimer Disease (AD)",[84,82],"NAD","2026-03-21",{"date":87,"type":34},"2026-03-24",{"date":89,"type":34},"2026-03-18",{"date":91,"type":19},"2027-06-01",{"name":40,"class":41},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":98,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":15,"minAge":75,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":20,"phases":103,"briefSummary":104,"conditions":105,"keywords":112,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":42},"100609612","the-geriatric-emergency-department-pharmacologic-harm-prevention-project-100609612","NCT07216846","The Geriatric Emergency Department Pharmacologic Harm Prevention Project","GREAT PHARM","Inclusion Criteria:\n\n* Patients over the age of 65 with a ground level fall\n\nExclusion Criteria:\n\n* hospice and\u002For DNR status.","110 Years",{"count":102,"type":19},1000,[22],"The goal of this project is to determine whether pharmacogenomic testing (using participants' DNA) can help optimize medication prescribing and reduce side effects in older adults taking five or more medications.\n\nThe main questions it aims to answer are:\n\n* Can DNA-based prescribing reduce medication-related side effects, especially falls and fall-related injuries?\n* Does providing pharmacogenomic results to primary care physicians improve medication safety compared with usual care?\n\nResearchers will compare two groups:\n\n1. DNA Care Pathway: Physicians receive patients' DNA results to guide prescribing.\n2. Emergency Department Care Pathway: Physicians provide usual care; DNA results are shared only after study completion.\n\nParticipants will:\n\n* Provide a cheek swab sample for DNA analysis (1 minute).\n* Receive monthly follow-up phone calls for 6 months to track falls, injuries, medication changes, and side effects.\n* Complete a fall and medication calendar.\n* Allow researchers to review primary care physician medical records for study outcomes.\n\nApproximately 1,000 participants will take part, with follow-up lasting about 6-7 months.",[106,107,108,109,110,111],"Fall","Fall Accident","Poly Pharmacy","Adverse Drug Events","Pharmacogenomic Drug Interaction","Pharmacogenomic Testing",[106,113,114,115],"Geriatric","Pharmacogenomic","adverse drug event",{"date":117,"type":34},"2026-01-08",{"date":119,"type":34},"2026-01-01",{"date":121,"type":19},"2027-12-31",{"name":40,"class":41},{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":74,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":129,"targetDuration":4,"studyType":20,"phases":131,"briefSummary":133,"conditions":134,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":42},"100586043","phase-3-lidocaine-versus-diphenhydramine-to-achieve-local-anesthesia-for-laceration-repairs-100586043","NCT06910241","Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs","Inclusion Criteria:\n\n* Lacerations requiring one layer of sutures\n* Lacerations appropriate for repair by emergency physicians\n\nExclusion Criteria:\n\n* Active bleeding from laceration\n* Complex lacerations requiring multiple layers\n* Lacerations to be repaired by a specialist service\n* Patients with allergies to either diphenhydramine or lidocaine\n* Laceration repairs would benefit from the use of epinephrine as an additive to the local anesthetic",{"count":130,"type":19},100,[132],"PHASE3","Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of diphenhydramine is noninferior to the use of lidocaine 1% when trying to achieve local anesthesia for simple laceration repair. Patients who present to the emergency department with a simple laceration will be enrolled in the study. Patients will be evaluated for the pain of the injection as well as the pain of the laceration repair procedure post injection.",[135],"Laceration of Skin","2026-01-06",{"date":36,"type":34},{"date":139,"type":34},"2025-09-03",{"date":141,"type":19},"2028-06-30",{"name":40,"class":41},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":150,"targetDuration":4,"studyType":20,"phases":152,"briefSummary":153,"conditions":154,"keywords":159,"overallStatus":166,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":4},"100537754","machine-learning-and-3d-image-based-modeling-for-body-weight-estimation-100537754","NCT06281938","Machine Learning and 3D Image-based Modeling for Body Weight Estimation.","Machine Learning and 3D Image-based Modeling for Real-time Body Weight and Body Composition Estimation During Emergency Medical Care.","Inclusion Criteria:\n\n\\- Any patient presenting to the Emergency Department of the study site, who will require any form of weight-based intravenous drug therapy, and who will be admitted to the hospital.\n\nExclusion Criteria:\n\n* Patients who are unable to provide consent.\n* Patients whose medical treatment could be negatively impacted by participation in the study.",{"count":151,"type":19},320,[22],"The goal of this randomized controlled clinical trial is to \\[learn about, test, compare etc.\\] in critically ill or injured cohorts of patients presenting to the Emergency Department. The main question\\[s\\] it aims to answer are:\n\n* Are weight estimates from a 3D camera system more accurate than standard methods of weight estimation?\n* Do patients who receive weight estimates with a 3D camera system have fewer drug dosing errors than patients receiving standard care?\n\nParticipants will either receive a weight estimate using a 3D camera system, or standard methods of care.\n\nResearchers will compare the 3D camera group to those with standard care to see if the weight estimates are more accurate, to see if drug dosing is more accurate, and to compare the incidence of adverse events related to medications in each group.",[155,156,157,158],"No Specific Conditions","Weight, Body","Drug Dose","Weight-Estimation",[160,161,162,163,164,165],"weight estimation","drug dosing","3D camera","total body weight","lean body weight","ideal body weight","NOT_YET_RECRUITING","2025-06-05",{"date":169,"type":34},"2025-06-06",{"date":171,"type":19},"2026-06",{"date":173,"type":19},"2027-09",{"name":40,"class":41},""]