[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Friedrich-Alexander-Universität Erlangen-Nürnberg\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":100},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100618546","lonely-in-depression-100618546",false,"NCT07333027","Lonely in Depression","Effects of Loneliness in the Treatment of Depression","Inclusion Criteria:\n\n* primary diagnosis of depression according to ICD-10 (F32 or F33), as diagnosed by a physician or clinical psychologist in conjunction with the M.I.N.I. Mini-International Neuropsychiatric Interview diagnostic tools\n* inpatient elective or emergency admission to one of the two psychiatric clinics; - age over 18 years\n* sufficient understanding of spoken and written German\n* informed voluntary consent\n\nExclusion Criteria:\n\n* a current lack of capacity to provide consent (e.g., pronounced psychotic symptoms, stuporous depressive syndrome, and thought constriction to suicidality)\n* previous participation in the study\n* pregnancy or breastfeeding\n* inpatient stay of less than 7 days, even if the patients initially met the inclusion criteria.","ALL","18 Years",{"count":19,"type":20},200,"ESTIMATED","3 Months","OBSERVATIONAL","The goal of this prospective study is to better understand the link between loneliness and depression in the inpatient psychiatric treatment of depression. It aims to answer:\n\nDo lonely and not lonely persons benefit the same way from inpatient depression treatment? Is loneliness a clinical relevant factor in inpatient treatment of depression? What are the underlying biopsychosocial mechanisms?\n\nParticipants will be asked to do some\n\n* self-report questionnaires\n* clinical interview\n* biosampling (blood, saliva, stool) at three main measurement timepoints (1. begin of inpatient treatment, 2. day of discharge, 3. three months after discharge).",[25,26],"Depression Disorder","Loneliness",[28,29,30,31,32],"loneliness","depression","prospective","biosampling","clinical","RECRUITING","2026-06-11",{"date":36,"type":37},"2026-06-15","ACTUAL",{"date":39,"type":37},"2026-02-05",{"date":41,"type":20},"2027-09",{"name":43,"class":44},"Friedrich-Alexander-Universität Erlangen-Nürnberg","OTHER",2,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":17,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},"100632917","improvement-of-understanding-of-pediatric-sacral-neuromodulation-therapeutic-strategies-and-outcome-variables-100632917","NCT07519915","Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables","Stimulation Modeling and Adaptive Response Tracking in Pediatric Gastrointestinal Motility Disorders","SMART-GUT","Inclusion Criteria:\n\n* informed consent of patient and care taker\n* gastrointestinal motility disorder, disregarding underlying diseases\n* exclusion of mechanical obstructions in the gastrointestinal passage\n* age between 3 and 18\n\nExclusion Criteria:\n\n* pregnancy\u002Fbreast feeding\n* decreased renal or thyroidal function\n* drug intake of Beta-blockers, antispasmodics, cyclopropane, bisulfite compounds, haloperidol, heroin, meperidine, metamizole, methadone, morphine, nitrofurantoin, opium alkaloids, phenobarbital, phenylbutazone, probenecid, rifamycin\n* contradictions for MRI\n* indication for analgosedation for MRI\n* inflammatory bowel diseases\n* fractures\u002Fdifferent anatomy in sacral region\n* epilepsy\n* presence of cardiac pacemakers","3 Years",{"count":56,"type":20},25,"INTERVENTIONAL",[59],"NA","The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders. By combining advanced neuroimaging, patient-specific biophysical modeling, electrophysiological characterization, and clinical translation, the SMART-GUT project establishes a comprehensive framework to systematically investigate neuromodulation in this pediatric population. This integrative approach enables a direct link between mechanism, targeting, and clinical outcome.",[62,63,64],"Gastrointestinal Motility Disorders in Children","Hirschsprung Disease","Constipation - Functional",[66,67,68,69],"pediatric gastrointestinal motility disorders","chronic constipation","Hirschsprung disease","sacral neuromodulation","2026-04-06",{"date":72,"type":37},"2026-04-09",{"date":74,"type":37},"2018-07-01",{"date":76,"type":20},"2029-12-31",{"name":43,"class":44},1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":86,"targetDuration":4,"studyType":57,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":78},"100490475","fistula-in-ano-in-infants-and-children-100490475","NCT05666609","Fistula-in-ano in Infants and Children","Fistula-in-ano in Infants and Children: Prospective, Randomized Clinical Trail on the Duration of Non-cutting Seton Placement","Inclusion Criteria:\n\n* any patient with FIA and treatment with non-cutting seton placement in our institution\n* regardless of underlying diagnoses\n* age 0-18 years\n\nExclusion Criteria:\n\n* none",{"count":87,"type":20},20,[59],"In this prospective, randomized trail, duration of non-cutting seton placement in patients with fistula-in-ano is evaluated.",[91],"Fistula in Ano","2025-08-31",{"date":94,"type":37},"2025-09-08",{"date":96,"type":37},"2023-01-01",{"date":98,"type":20},"2027-12-31",{"name":43,"class":44},""]