[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fundació d'investigació Sanitària de les Illes Balears\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":155},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,73,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100633611","application-of-3d-reconstruction-for-preoperative-strategy-of-locally-advanced-colon-cancer-100633611",false,"NCT07528937","Application of 3D Reconstruction for Preoperative Strategy of Locally Advanced Colon Cancer","Randomized Multicenter Study Protocol: Application of 3D Reconstruction for Preoperative Strategy of Locally Advanced Colon Cancer","Inclusion Criteria:\n\n1. Patients of both sexes, aged ≥18 years.\n2. Adenocarcinoma of the right, left, sigmoid and recto-sigmoid junction that have cT3 or cT4a\u002Fb according to the eighth TNM edition of the American Joint Committee on Cancer (AJCC). Pre-treatment diagnosis by imaging (CT) test.\n3. Lymph node extension: cN0, the presence of cN1\u002F2 according to AJCC TNM 8th edition is allowed as long as they can be resected. Pretreatment diagnosis by imaging (CT) test.\n4. Patients who access and sign informed consent for the surgical intervention.\n\nExclusion Criteria:\n\n1. Suspected carcinomatosis on preoperative CT or intraoperative finding\n2. Suspected distant metastasis on preoperative CT or intraoperative finding\n3. Patients with tumors with infiltration considered to be unresectable (pre-surgical or intraoperatively), since the anatomical-pathological analysis will not be available.","ALL","18 Years",{"count":19,"type":20},168,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of this study is to assess the usefulness of a mathematical model of three-dimensional image process and reconstuction (3D-IPR) as a surgical planner in locally advanced colon cancer. In addition to comparing the diagnostic accuracy of this planner with that of the CT regarding the infiltration of neighbouring structures.",[26,27,28],"Colon Neoplasms","Locally Advanced Colon Cancer","3D Reconstruction",[30,31,28],"Locally advanced colon cancer","Colon neoplasm","NOT_YET_RECRUITING","2026-04-16",{"date":35,"type":36},"2026-04-21","ACTUAL",{"date":38,"type":20},"2026-05-01",{"date":40,"type":20},"2031-05-01",{"name":42,"class":43},"Fundació d'investigació Sanitària de les Illes Balears","OTHER_GOV",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},"100560386","effect-of-supplementation-with-creatine-on-the-recovery-of-ischemic-stroke-100560386","NCT06576466","Effect of Supplementation With Creatine on the Recovery of Ischemic Stroke","Effect of Supplementation With Creatine on the Early Recovery of Ischemic Stroke: A Randomized Clinical Trial","SUCRE","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Recent diagnosis of ischemic stroke (from 24 hours to 5 days) .\n* Neurological deficit due to the stroke that affects mobility (paresis and\u002For ataxia) and requires motor rehabilitation.\n* Ability to understand and sign the informed consent form, or failing that, have sufficient support to carry out the correct follow-up of the study.\n\nExclusion Criteria:\n\n* Moderate-severe disability prior to stroke, defined by an mRS\\>2.\n* Unstable or severe clinical situation that prevents active rehabilitation.\n* Neurological deficit due to stroke that prevents walking without help from another person. The use of support with a cane, crutch or walker is permitted.\n* Moderate or severe dysphagia that makes therapeutic adherence difficult.\n* Use of creatine supplements in the last 3 months, or use of anabolic products in the last 3 months.\n* Severe kidney disease (GFR \\\u003C30ml\u002Fmin\u002F1.73 m2).\n* Musculoskeletal pathology that prevents assessment of muscle strength. For example: fractures, severe osteoarthritis, ligament tears or tendinopathies.\n* History of allergic reactions to creatine.\n* Pregnancy or breastfeeding.\n* Simultaneous participation in another clinical trial.","80 Years",{"count":54,"type":20},92,[23],"Stroke is a leading cause of disability and the second leading cause of death worldwide. Most strokes are ischemic, caused by acute arterial occlusion. Post-stroke treatment focuses on secondary prevention and rehabilitation, but few treatments address functional recovery. Creatine, a supplement known for improving physical performance, may aid in the recovery of stroke patients, reducing sarcopenia and improving strength among other effects. This pilot study will investigate the effectiveness of creatine supplementation in enhancing physical and functional recovery in ischemic stroke patients. The study will involve a randomized, double-blind clinical trial comparing creatine monohydrate to a placebo.",[58],"Stroke, Ischemic",[60,61,62],"stroke","creatine","sarcopenia","RECRUITING","2025-07-02",{"date":66,"type":36},"2025-07-08",{"date":68,"type":36},"2024-09-27",{"date":70,"type":20},"2027-07-01",{"name":42,"class":43},1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":16,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":93,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},"100593817","empowering-healthy-lifestyle-personalised-intervention-to-prevent-and-control-obesity-the-healthyw8-project-100593817","NCT07011368","Empowering Healthy Lifestyle Personalised Intervention to Prevent and Control Obesity: The HealthyW8 Project","Empowering Healthy Lifestyle Behaviour Through Personalized Intervention Portfolios to Prevent and Control Obesity During Vulnerable Stages of Life: The HealthyW8 Project.","HealthyW8","Inclusion Criteria:\n\n* Overweight (BMI between 25-30 kg\u002Fm\\^2)\n* To have a smart phone\n\nExclusion Criteria:\n\n* Individuals with manifest chronic diseases\n* Individuals with cognitive diseases\n* Individuas not able to lead an independent life",true,"7 Years",{"count":84,"type":20},2720,[23],"The goal of the HealthyW8 study (an intervention study) is:\n\nTo assess the usefulness and effects of a digital-based healthy lifestyle recommender system (HRLS) on the prevention of obesity in the following propulations: schoolchildren (5-10 y) and their parents, young adults (18-25 y) and elders (\\>65 y).\n\nThe main questions it aims to answer are:\n\nOutcome 1: To select and validate a tool-assisted 3-mo intervention (mostly digital) by iteratively testing the HLRS on reducing risk of overweight\u002Fobesity among the described age groups.\n\nOutcome 2: To assess the effect of 1-y interventions (mostly digital) with the HLRS described and further iteratively improved previously (outcome 1) on reducing risk of overweight\u002Fobesity at described ages.\n\nResearchers will compare the intervention group before the intervention (baseline) and after it (3-mo intervention trial), or control group (standard care) vs. Intervention group (1-y intervention) to see changes on changes in overweight\u002Fobesity, and related parameters (body composition and biomarkers).\n\nParticipants will follow the HLRS recommendations (meal plans, physical activity and sleep pattern measures and recommendations, assessment of behavioural\u002Fpsychological aspects, and motivational features through digital devices), which will be assessed by means of measurement of body weight, body composition, and biomarkers.",[88,89,90,91,92],"Obesity Prevention","Obesity and Overweight","Obesity and Obesity-related Medical Conditions","Digital Health","Behavioural Science Interventions to Improve Health Equity",[94,95,96,97,98,99,100,101,102],"Healthy lifestyle recommender system","digital empowerment","health literacy","personalised prevention","pre-obesity biomarkers","mHealth","Human Digital Twin","behavior change techniques","physical activity","2025-06-27",{"date":105,"type":36},"2025-07-01",{"date":105,"type":20},{"date":108,"type":20},"2028-06-30",{"name":42,"class":43},13,{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":81,"sex":16,"minAge":118,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":21,"phases":122,"briefSummary":123,"conditions":124,"keywords":130,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100592640","effects-of-a-multifaceted-school-based-intervention-to-protect-mental-health-and-prevent-suicidal-behaviour-in-adolescents-in-spain-100592640","NCT06996054","Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain","DEVELOPMENT AND EVALUATION OF A MULTIFACETED SCHOOL-BASED INTERVENTION TO PROTECT MENTAL HEALTH AND PREVENT SUICIDAL BEHAVIOR AMONG ADOLESCENTS IN SPAIN","Inclusion Criteria:\n\n* Students enrolled in the 2nd or 3rd year of compulsory secondary education during the 2026-2027 academic year in the Balearic Islands, Spain.\n* Aged between 12 and 16 years at the time of recruitment.\n* Provision of written informed consent from both the student and at least one parent\u002Flegal guardian.\n* Attending school centres with a student population composed of no more than 75% of a single gender.\n* Enrollment in a participating classroom randomly selected for the study.\n\nExclusion Criteria:\n\n* Presence of cognitive, developmental, or language impairments that, in the judgment of school staff or study personnel, would prevent the student from understanding the intervention content or completing the study assessments reliably.\n* Students currently receiving intensive psychological or psychiatric treatment for acute suicidality or severe mental health conditions that require individualized clinical management beyond the scope of a school-based programme.\n* Students or parents who explicitly decline participation in specific intervention components, such as group discussions on suicide or mental health.\n* Participation in a concurrent school-based mental health programme that could confound the effects of the intervention.","12 Years","16 Years",{"count":121,"type":20},2280,[23],"What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain. Suicide is one of the leading causes of death among young people. Many teens who think about or attempt suicide are also struggling with mental health problems like depression. Schools offer a unique opportunity to help because almost all adolescents attend school regularly.\n\nWhat will happen in the study?\n\nThe study will include about 2,280 students aged 12 to 16 years from 38 secondary schools in the Balearic Islands, Spain. Schools will be randomly assigned to one of two groups:\n\nIntervention group: Students will participate in four weekly classroom sessions led by trained psychologists. These sessions will help students learn about mental health, manage their emotions, recognize signs of distress in themselves or others, and ask for help when needed. At the same time, parents and teachers will follow a digital training program with videos and resources to help them support students' mental health and recognize warning signs.\n\nControl group: Students will receive a minimal intervention, which includes educational posters displayed in classrooms.\n\nWhat is the purpose of this program? The main goal is to reduce suicidal thoughts and behaviors. The program also aims to improve students' overall mental well-being, reduce depression symptoms, and encourage help-seeking behaviors. It also helps parents and teachers feel more confident in supporting teens who may be at risk.\n\nHow will the study be evaluated? Students will complete questionnaires at the start of the study and again after six months. These surveys will ask about mental health, suicidal thoughts, emotional well-being, self-harm, substance use, and experiences with bullying. Parents and teachers will also complete surveys about their knowledge and confidence in supporting students.\n\nWhy is this study important? There is an urgent need to find effective ways to prevent suicide and support young people's mental health. This program involves students, families, and schools in working together to create a safe and supportive environment. If the program works, it could be used in schools throughout Spain and possibly in other countries too.\n\nWho is funding this study? The study is funded by Fundación Mutua Madrileña.",[125,126,127,128,129],"Suicide Attempt","Depression","Adolescent Mental Health","Self-Harm","Suicidal Ideation and Behavior",[131,132,133,134,126,135,136,137,138,139,140,141,142,143,144,145,146],"School-based intervention","Suicide prevention","Suicidal ideation","Suicidal behavior","Adolescents","Mental health promotion","Psychoeducation","Gatekeeper training","Teachers","Parents","Digital health","Cluster randomized controlled trial","Spain","Secondary education","Emotional regulation","Self-harm","2025-05-21",{"date":149,"type":36},"2025-05-30",{"date":151,"type":20},"2025-10",{"date":153,"type":20},"2027-06",{"name":42,"class":43},""]