[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fundación Universidad Católica de Valencia San Vicente Mártir\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":233},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,50,88,114,147,176,209],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100590595","managing-chronic-spinal-pain-with-exercise-and-neuromodulation-100590595",false,"NCT06969456","Managing Chronic Spinal Pain With Exercise and Neuromodulation","Patient-centered Management of Chronic Spinal Pain by Addressing the Peripheral and Central Component With Exercise and Non-invasive Neuromodulation: A Randomized Control Trial (RCT)","UCV\u002FPSPS","Inclusion Criteria:\n\n* Have a diagnostic of PSPS-T2\n* Neuropathic pain (DNA4 ≥ 4)\n* Patients older than 18 years\n* ≥ 6 months with pain\n* VAS score ≥ 7\n\nExclusion Criteria:\n\n* Previous or programmed surgeries in abdominal area\n* Pregnant or lactating\n* Severe fractures or pathologies\n* Spine structural deformity\n* Neurologic or psychiatric issues","ALL","18 Years","70 Years",{"count":21,"type":22},42,"ESTIMATED","INTERVENTIONAL",[25],"NA","Chronic spinal pain is a multifaceted condition frequently characterized by an absence of discernible structural causes, manifesting in symptoms such as significant disability and diminished quality of life. Persistent Spinal Pain Syndrome Type 2 (PSPS-T2) represents a common variant, implicating both peripheral and central nervous system mechanisms. This study investigates the synergistic effects of transcranial direct current stimulation (tDCS) in conjunction with motor control exercises on PSPS-T2 patients who have not responded to conventional treatments. A randomized controlled trial (RCT) will be conducted to compare an experimental group (tDCS + exercise) with a control group (exercise only), with the objective of enhancing functionality, alleviating pain levels, and improving psychological well-being. The findings may contribute to the development of more effective, patient-centered treatment strategies.",[28,29],"Spinal Pain Syndrome","Chronic Pain (Back \u002F Neck)",[31,32,33,34,35,36],"Chronic spinal pain","neuromodulation","motor control exercises","biopsychosocial approach","disability","quality of life","RECRUITING","2025-12-01",{"date":40,"type":41},"2025-12-08","ACTUAL",{"date":43,"type":41},"2025-10-27",{"date":45,"type":22},"2027-01-01",{"name":47,"class":48},"Fundación Universidad Católica de Valencia San Vicente Mártir","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":67,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":82,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":49},"100587747","orofacial-pain-self-management-personality-moderation-effect-100587747","NCT06932406","Orofacial Pain Self-management: Personality Moderation Effect","Orofacial Pain Self-management: Personality Moderation Effect - Randomized Clinical Trial","Inclusion Criteria:\n\n* The patient presents TMDs diagnosed according to the CD\u002FTMD classification.\n* Age between 18 and 65.\n* Presence of pain in mandibular, temporal, facial, peri-auricular and\u002For auricular regions.\n* Presence of chronic orofacial pain. Defined by the ICD-11 as orofacial pain or headache that occurs for more than two hours a day for 50% of the days of the last three months.\n* Orofacial pain is related to TMDs according to the International Classification of Headaches.\n* Moderate pain intensity, corresponding to a weekly average of at least 30 mm on a 100 mm VAS (validated representation of moderate pain on the VAS scale = 31-54 mm)\n\nExclusion Criteria:\n\n* Concomitant rheumatic systemic pathologies.\n* History of trauma or recent surgical intervention in the head, face, neck or chest.\n* Presence of intraoral infections or odontogenic pain.\n* Headache of neuropathic origin (trigeminal neuralgia, Arnold neuralgia, etc.).\n* Being receiving therapy (except rescue pharmacological therapy) for this disorder or pain.\n* Cognitive impairment that prevents the follow-up of an educational program (determined through the MoCA questionnaire)","65 Years",{"count":59,"type":22},98,[25],"The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed by the TMD clinical practice guidelines. It also evaluates its effect on function and various psychosocial variables.\n\nAs a secondary objective, this work proposes to study the variability between patients, in terms of personality factors, as moderators of the effect of treatment on pain perception. Including in the proposed statistical models certain covariates such as perception and\u002For coping with stress, anxiety and other psychosocial variables.\n\nThis is a randomized clinical trial with two intervention groups and three measurement times (T0; pre-intervention, T1; post-5 weeks and T2; post-6 months). The experimental group will be applied a protocol based on self-management, which includes: therapeutic education, cognitive-behavioral tools, therapeutic exercise of the temporomandibular region, mind-body strategies and modifications of aspects related to lifestyle. The control group will carry out an intervention program based on the Clinical Practice Guidelines for the Management of Temporomandibular Joint Disorders. Therefore, using a set of tools based on therapeutic education, cognitive-behavioral tools for bruxism and other parafunctional habits, temporomandibular region exercises and manual therapy.",[63,64,65,66],"Chronic Orofacial Pain","Temporomandibular Disorder (TMD)","Temporomandibular Disorders (TMD)","Temporomandibular Dysfunction (TMD)",[68,69,70,71,72,73,74,75,76,77,78,79,80,81],"Temporomandibular disorder","Orofacial pain","Self-management","self-efficacy","therapeutic exercise","therapeutic education","cognitive behavioral","mind-body techniques","Lifestyle modification training","manual therapy","personality","psychosocial","biopsychosocial","physiotherapy",{"date":40,"type":41},{"date":84,"type":41},"2025-11-28",{"date":86,"type":22},"2026-05-24",{"name":47,"class":48},{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":23,"phases":99,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":111,"leadSponsor":113,"locationsCount":49},"100578969","effects-of-tdcs-on-motor-cortex-during-acl-recovery-100578969","NCT06818201","Effects of tDCS on Motor Cortex During ACL Recovery","Effects of Transcranial Direct Current Stimulation Over Motor Cortex During Recovery of ACL Patients","Inclusion Criteria:\n\n* Diagnosis complete ACL tear through clinical evaluation and MRI imaging.\n* Patients who have received surgical intervention.\n* Aged between 16 and 40 years.\n* Tegner activity level of 4 or higher.\n\nExclusion Criteria:\n\n* Rupture, such as tendons, cartilage, bones, or ligaments.\n* Absence of any pre-existing or current lower limb pathologies, such as open surgeries, knee arthroscopies, or femur\u002Ftibia fractures.\n* Neuromuscular or metabolic diseases.\n* Concussion within the past six months are not eligible.\n* Cranial surgery or have intracranial metal clips are ineligible.\n* Taking medications that affect neuronal activity.\n* Neurological diseases or disorders are not eligible for participation.","16 Years","40 Years",{"count":98,"type":22},54,[25],"Anterior Cruciate Ligament (ACL) is a prevalent injury, particularly among young and physically active individuals. The efficacy of transcranial direct current stimulation (tDCS) and exercise-based rehabilitation on neuromuscular control in post-ACL reconstruction patients is evaluated, and these techniques are combined.",[102],"Anterior Cruciate Ligament Reconstruction Rehabilitation",[104,105,106,107],"motor control","Anterior Cruciate Ligament","exercise","tDCS",{"date":109,"type":41},"2025-12-02",{"date":84,"type":41},{"date":112,"type":22},"2027-12-27",{"name":47,"class":48},{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":17,"minAge":122,"maxAge":123,"enrollmentInfo":124,"targetDuration":4,"studyType":23,"phases":126,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":146},"100539787","effectiveness-of-rehabilitation-protocol-in-patients-with-shortened-posterior-leg-muscles-100539787","NCT06308380","Effectiveness of Rehabilitation Protocol in Patients With Shortened Posterior Leg Muscles","Effectiveness of Rehabilitation Protocol in Patients With Shortened Posterior Leg Muscles, Whether or Not Combined With Ultrasound- Guided Surgery","EREPSOLM","Inclusion Criteria:\n\n* Patients with shortened posterior musculature.\n* Chronic ankle pain.\n* Limitations in activities of daily living.\n* Atypical gait.\n* Clubfoot.\n\nExclusion Criteria:\n\n* Previous MMII surgeries.\n* Neuropathic pain.\n* Bony cap equinus.\n* Analgesic physiotherapy.","20 Years","90 Years",{"count":125,"type":22},40,[25],"The goal of this clinical study is to develop a specialized rehabilitation exercise protocol designed for patients diagnosed with foot pathologies and calf muscle shortening, regardless of their choice to undergo minimally invasive ultrasound-guided surgery. The primary focus is to assess disparities in outcomes, particularly in the recovery of ankle mobility degrees. Additionally, for patients opting for minimally invasive ultrasound-guided surgery, the study aims to evaluate the resumption of both sporting activities and daily routines using the aforementioned specific rehabilitation protocol.\n\nThe primary questions this study aims to answer are:\n\n* How does the proposed rehabilitation protocol impact ankle mobility recovery for patients with foot pathologies and calf muscle shortening?\n* What are the differences observed in the return to sporting activities and daily life among patients undergoing minimally invasive ultrasound-guided surgery, following the prescribed protocol?\n\nParticipants enrolled in this study will be engaged in:\n\nUndertaking the specified rehabilitation exercises tailored for foot pathologies and calf muscle shortening.\n\nThose opting for minimally invasive ultrasound-guided surgery will follow the same rehabilitation protocol post-surgery to assess its impact on their return to normal activities.\n\nIf there exists a comparison group:\n\nResearchers will compare participants who undergo minimally invasive ultrasound-guided surgery against those who choose other treatment options to discern any differential effects on ankle mobility recovery and resumption of activities.",[129,130,131],"Equinus Deformity of Foot","Gastrocnemius Equinus","Contracture",[133,134,135,136,137],"foot deformity","calf shortening","foot and ankle disease","stretching and muscle strengthening","exercise post surgery","2025-05-07",{"date":140,"type":41},"2025-05-11",{"date":142,"type":41},"2024-03-10",{"date":144,"type":22},"2025-06-10",{"name":47,"class":48},3,{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":153,"eligibilityCriteria":154,"healthyVolunteers":11,"sex":155,"minAge":156,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":23,"phases":159,"briefSummary":160,"conditions":161,"keywords":164,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":171,"completionDateStruct":173,"leadSponsor":175,"locationsCount":49},"100576290","effect-of-neuromodulation-and-therapeutic-exercise-in-urinary-incontinence-100576290","NCT06783374","Effect of Neuromodulation and Therapeutic Exercise in Urinary Incontinence","Effect of a Peripheral and Central Neuromodulation Protocol Combined With the Application of Therapeutic Exercise in Patients Diagnosed With Urinary Incontinence. A Randomized Control Trial (RCT)","UCV\u002FINCONTINEN","Inclusion Criteria:\n\n* Present with a diagnosis of urinary incontinence or overactive bladder\n* Women of menopausal age (\\>45 years)\n* ≥3 months of duration\n* Fulfill the established criteria for patient selection for neuromodulation treatment (urge urinary incontinence)\n* Speak native Spanish or English\n\nExclusion Criteria:\n\n* Prior or scheduled surgical procedures in the lumbar or abdominal region\n* Presence of fractures or severe pathological conditions\n* Current pregnancy or potential for pregnancy during the study period\n* Neurological or psychiatric disorders\n* Presence of stress urinary incontinence\n* Female subjects with autoimmune diseases or malignancies\n* Belonephobia\n* Subjects who have undergone previous neuromodulation","FEMALE","45 Years",{"count":158,"type":22},63,[25],"Urge urinary incontinence (UUI) is a component of the condition known as overactive bladder, a severe and debilitating chronic disorder affecting healthcare systems worldwide. The efficacy of therapeutic exercise and neuromodulation in the treatment of UUI is evaluated, and these techniques are combined.",[162,163],"Urge Urinary Incontinence","Overactive Bladder (OAB)",[165,106,166,167],"Menopause","Neuromodulation","Posterior tibial nerve","2025-04-10",{"date":170,"type":41},"2025-04-13",{"date":172,"type":41},"2025-03-04",{"date":174,"type":22},"2026-11-10",{"name":47,"class":48},{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":183,"sex":155,"minAge":184,"maxAge":185,"enrollmentInfo":186,"targetDuration":4,"studyType":23,"phases":188,"briefSummary":189,"conditions":190,"keywords":194,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":49},"100580572","effects-of-a-multidisciplinary-intervention-on-fall-risk-and-urinary-incontinence-in-older-women-100580572","NCT06839040","Effects of a Multidisciplinary Intervention on Fall Risk and Urinary Incontinence in Older Women","FIRE-WOMEN","Inclusion Criteria:\n\n* Woman, aged between 60 and 80 years.\n* Not having done physical exercise in the last 3 months.\n* Present UI (SUI, UUI or MUI) after clinical diagnosis.\n* Score greater than 90 on the Barthel Scale.\n* Not present pathologies or functional alterations that limit the practice of physical exercise.\n* Not present severe cognitive alterations or mild cognitive deficit (Global Deterioration Scale less than or equal to 2 or Mini Mental State Examination greater than or equal to 25 points).\n* Maintain walking without support products.\n* Carry out 80% of the total sessions\n\nExclusion Criteria:\n\n* Intake of medication that could affect the performance of the exercise or alter the variables studied.\n* Present grade II-IV uterine prolapses.\n* Clinical disease or syndrome (chronic or acute cardiovascular, neurological, respiratory or musculoskeletal disorders) that may interfere with the performance of the intervention and evaluation.\n* Present visual and\u002For auditory alterations that make it difficult to carry out the intervention and evaluation.",true,"60 Years","80 Years",{"count":187,"type":22},120,[25],"This will be a quantitative, quasi-experimental, and longitudinal study spanning 18 weeks of intervention, followed by a 24-week follow-up, scheduled to begin in January 2025.\n\nThe primary objective of this study is to evaluate the effects of a multidisciplinary intervention comprising physiotherapy, physical exercise, and psychoeducation on fall risk and urinary incontinence in non-institutionalized older adult women aged 60 to 80 years. Participants will be randomly assigned to one of four groups:\n\n1. A multicomponent exercise group with verbal instructions for pelvic floor exercises.\n2. A multicomponent exercise group with verbal instructions for pelvic floor exercises and psychoeducation.\n3. A multicomponent exercise group without verbal instructions for pelvic floor exercises.\n4. A control group.\n\nMulticomponent exercise sessions will be conducted twice a week, while the psychoeducation group will participate in five group therapy sessions throughout the program. The variables to be analyzed include balance, strength, power, pelvic floor function, quality of life, and self-esteem.",[191,192,193],"Urinary Incontinence","Frailty","Balance Impairment",[195,196,197,198,199,200],"older women","pelvic floor","balance","multicomponent exercise","urinary incontinence","phsychoeducation","2025-02-16",{"date":203,"type":41},"2025-02-21",{"date":205,"type":41},"2025-02-03",{"date":207,"type":22},"2025-12-28",{"name":47,"class":48},{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":4,"eligibilityCriteria":215,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":185,"enrollmentInfo":216,"targetDuration":4,"studyType":23,"phases":218,"briefSummary":219,"conditions":220,"keywords":222,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":226,"startDateStruct":228,"completionDateStruct":230,"leadSponsor":232,"locationsCount":49},"100537031","spinal-cord-stimulation-combined-with-exercise-in-persistent-spinal-pain-syndrome-100537031","NCT06272539","Spinal Cord Stimulation Combined With Exercise in Persistent Spinal Pain Syndrome","Spinal Cord Stimulation Combined With Exercise in Patients Diagnosed With Persistent Spinal Pain Syndrome. A Randomized Control Trial (RCT)","Inclusion Criteria:\n\n* Have a diagnostic of PSPS-T1\u002F2 with leg pain and back pain,\n* Patients older than 18 years\n* 6 months with pain\n* Visual Analogue Scale score \\>7\n* Spanish native language\n\nExclusion Criteria:\n\n* Previous surgeries in abdominal area\n* Pregnant or lactating\n* Severe fractures or pathologies\n* Spine structural deformity\n* Neurologic or psychiatric issues.",{"count":217,"type":22},36,[25],"Introduction. At the neurophysiological level, it is possible to observe an increase in the central processing of pain in patients diagnosed with persistent Spinal Pain Syndrome (PSPS-T1\u002F2), potentially stemming from dysfunctions in the endogenous facilitation and inhibition of pain. Administration of high doses of spinal cord stimulation to individuals with PSPS-T1\u002F2 may induce supraspinal descending activation. Similarly, exercise is recognized as a fundamental aspect of spinal pain management. Studies have demonstrated its impact on neurophysiological factors, including the release of spinal and supraspinal beta-endorphins, which activate μ-opioid receptors. Therefore, the purpose of this study will be to examine the effect of SCS in combination with lumbo-pelvic stability core training on perceived low back pain, quality of life and disability in failed back surgery syndrome (FBSS) patients. Methods\u002FMaterials. A double-blind randomized clinical trial (RCT) has been designed. All participants will be randomized from a pre-set sequence. The intervention design has been elaborated from the CONSORT guidelines. This study protocol has been approved by the Ethics Committee in research of Salamanca Health Area (protocol number PI 2023 101435 in (24\u002F01\u002F2024) in accordance with the ethical guidelines of the Helsinki declaration. Sample size was calculated using G Power® Sample size software (University of Düsseldorf). The calculation was based on a moderate effect size of 0.4 (partial η2 = 0.40, α = .05, power = 0.90), resulting in a total of 28 patients. Assuming a 30% dropout rate, 36 participants will be recruited in total. Two sessions per week will be scheduled for 8 weeks with a total of 16 sessions. Each work session will have a duration of 60 minutes. The exercise will be adapted according to the phases based on the results already published, limiting in each phase the degrees of flexion and extension of the spine in order to avoid the risk of electrode migration. Primary outcomes will be functionality, satisfaction, strength, psychosocial variables, quality of life and pain perception.",[221],"Failed Back Surgery Syndrome",[223,224],"Spinal Cord Stimulation","Exercise","2024-08-26",{"date":227,"type":41},"2024-08-28",{"date":229,"type":41},"2024-04-09",{"date":231,"type":22},"2026-01-01",{"name":47,"class":48},""]