[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Fundacin Biomedica Galicia Sur\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":220},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,48,77,101,138,168,191],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100645190","immersive-virtual-reality-applied-to-therapeutic-physical-exercise-in-cellular-therapy-100645190",false,"NCT07679958","Immersive Virtual Reality Applied to Therapeutic Physical Exercise in Cellular Therapy","RVI-ET","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Signed informed consent.\n* Patients eligible for CT scan at the Alvaro Cunqueiro Hospital.\n* Patients capable of performing therapeutic exercise independently, based on an objective initial functional assessment.\n* The clinical investigator, in their professional judgment, determines that the patient can adhere to all study requirements.\n\nExclusion Criteria:\n\n* Patients under 18 years of age.\n* Any medical condition or mental illness that could interfere with understanding HIP and CI.\n* Patients participating in another clinical trial.\n* Balance disorders that increase the risk of falls.\n* Severe visual and\u002For auditory impairments that prevent participation in the session.\n* History of vertigo, seizures, or epileptic fits.","ALL","18 Years",{"count":19,"type":20},144,"ESTIMATED","INTERVENTIONAL",[23],"NA","Cell therapy (CT), including hematopoietic stem cell transplantation (HSCT) and advanced CAR T-cell therapies, is used for the treatment of oncohematological and other diseases. HSCT is associated with treatment-related toxicities, including fatigue, muscle weakness, and reduced functional capacity due to intensive conditioning chemotherapy, immunosuppressive treatments, corticosteroids, and complications such as infections or graft-versus-host disease. Emotional symptoms, including anxiety, depression, fear, and frustration, also affect patients' recovery and ability to regain functional independence. Evidence indicates that exercise interventions improve emotional well-being, fatigue, quality of life, physical function, cardiovascular fitness, and muscle mass in patients with hematological malignancies and HSCT recipients.\n\nVirtual reality (VR) has emerged as an innovative tool in rehabilitation, supporting patient motivation, exercise guidance, and monitoring. Immersive virtual reality (IVR), through head-mounted displays and multisensory environments, enhances the sense of presence and engagement. Studies suggest that IVR-based exercise programs are feasible, improving functional abilities, quality of life, satisfaction, and adherence.\n\nSince 2017, a Therapeutic Exercise program for patients admitted for HSCT has been implemented at Álvaro Cunqueiro Hospital (Vigo) through collaboration between the Physiotherapy Unit and the Hematology Department. Before admission, patients undergo a physical assessment, receive an individualized exercise plan, education, and a therapeutic exercise guide. Based on clinical experience, the team hypothesizes that integrating IVR into therapeutic exercise may improve motivation, adherence, and emotional well-being during hospitalization.",[26,27,28,29,30],"Hematologic Diseases","Hematopoietic Stem Cell Transplantation","Cellular Therapy","Quality of Life","Oncologic Disorders",[32,33,34],"Therapeutic Exercise","Immersive virtual reality","Cellular therapy","NOT_YET_RECRUITING","2026-06-25",{"date":38,"type":39},"2026-07-01","ACTUAL",{"date":41,"type":20},"2026-07-24",{"date":43,"type":20},"2029-06-01",{"name":45,"class":46},"Fundacin Biomedica Galicia Sur","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":47},"100616849","clinical-utility-of-the-numerical-verbal-scale-nvs-and-the-pain-and-functional-activity-scale-pfas-in-the-management-of-rescue-analgesia-in-acute-postoperative-pain-randomized-study-100616849","NCT07310953","Clinical Utility of the Numerical Verbal Scale (NVS) and the Pain and Functional Activity Scale (PFAS) in the Management of Rescue Analgesia in Acute Postoperative Pain. Randomized Study.","EVN\u002FEDAF","Inclusion Criteria:\n\n* Scheduled surgery with VATS admission\n* Age \\> 18 years\n* Signed informed consent\n\nExclusion Criteria:\n\n* Cognitive-mental deficit assessed using the Pfeiffer questionnaire. Patients with more than two errors if they have a university degree and more than three errors if they do not have a university degree are excluded from the study.\n* Allergy to any of the analgesic drugs listed on the data collection sheet (Paracetamol \u002F NSAIDs \u002F Metamizole \u002F Dexamethasone \u002F Local anesthetics \u002F Morphine \u002F Fentanyl).\n* Patients who, in the preoperative survey, present any degree of functional limitation according to the FAS scale (Grade B and C).\n\nWithdrawal Criteria:\n\n* If the patient withdraws consent.\n* If the patient experiences delirium, as measured by a positive CAM (Confusion Assessment Method) scale, following surgery.",true,{"count":57,"type":20},76,[23],"Adequate postoperative pain management, along with mobilization and early oral nutrition, is the foundation for optimal recovery after surgery.\n\nUnidimensional pain scales (Numerical Verbal Rating Scale - NRS, Visual Analogue Scale - VAS, Categorical Scale - CRS, Facial Pain Scale - FPS) do not adequately reflect a patient's actual analgesic needs. Basing analgesic treatment on the classic algorithm of administering opioids if pain is greater than 4 on the NRS, without considering functional impairment, has been shown to be a cause of overtreatment in surgical wards.\n\nThe Functional Activity Score (FAS) is the simplest scale, designed for bedside application and geared toward therapeutic decision-making. R: Able to perform any activity; B: Pain prevents some activity; C: Unable to perform any activity.\n\nGiven the need to standardize functional limitation when measuring postoperative pain, we propose the Pain and Functional Activity Scale (PFAS), which combines the NVA (Non-Visual Analogue Scale) with the Functional Activity Scale. Specifically, pain on movement would be recorded using the NVA in motion (NVAm), along with functional limitation (A, B, or C). The rescue analgesia treatment algorithm adapted to the PFAS would involve treating patients with pain greater than 4 on the NVA whenever it represents a severe limitation of their functional activity (C).\n\nIn this study, we aim to evaluate whether there are significant differences in the proportion of patients who meet the criteria for needing rescue analgesia according to the NVA compared to the proportion of patients who meet the criteria for needing rescue analgesia established by the PFAS, during the 2-day postoperative period.\n\nTo this end, an experimental, longitudinal, prospective, randomized, single-blind study for the data analyzer will be carried out, where a group that will receive rescue analgesia if VNS\\>4 and another if VNSm\\>4 + FAS C will be compared in the first two days of postoperative surgical patients of the surgeries selected in the EOXI of Vigo.",[61,62,63,64],"Analgesia","Post Operative Pain","Acute Pain","Functional; Anesthesia",[66,67],"numerical verbal scale","Functional Activity Score","RECRUITING","2026-02-17",{"date":71,"type":39},"2026-02-18",{"date":73,"type":39},"2025-10-30",{"date":75,"type":20},"2026-09-30",{"name":45,"class":46},{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":55,"sex":84,"minAge":17,"maxAge":4,"enrollmentInfo":85,"targetDuration":87,"studyType":88,"phases":4,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":47},"100621899","cardiovascular-research-in-embarazo-and-maternity-emma-study-on-heart-rate-variability-and-hemodynamic-adaptations-during-pregnancy-and-postpartum-100621899","NCT07376616","Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.","EMMA","Inclusion Criteria:\n\n* Over 18 years of age\n* Pregnancy from the third month of gestation\n* No pre-existing cardiovascular disease\n* Good cognitive level\n* Sign informed consent\n\nExclusion Criteria:\n\n* Diabetes mellitus\n* Hyperthyroidism\n* Hypothyroidism\n* Chronic hypertension diagnosed before pregnancy\n* Heart failure\n* Ischemic heart disease or malignant ventricular arrhythmias (ventricular fibrillation, ventricular tachycardia, grade 2 or 3 AV block, atrial fibrillation in patients with Wolff-Parkinson- White syndrome, paroxysmal fibrillation or flutter with rapid ventricular response and hemodynamic deterioration, uncontrolled supraventricular tachycardia)\n* Exercise-induced ischaemia\n* Unstable angina\n* Disease not susceptible to revascularization\n* Associated valvular heart disease\n* Chronic kidney disease\n* Degenerative neurological condition\n* Brain aneurysms\n* Arteriovenous malformations\n* History of transient cerebral infarction (ICTUS)\n* Migraines diagnosed\n* Epilepsy\n* Brain or spinal cord injury\n* Tumors\n* Diseases of the respiratory tract\n* Diseases of lung tissue\n* Diseases of pulmonary circulation","FEMALE",{"count":86,"type":20},242,"21 Months","OBSERVATIONAL","Heart rate variability (HRV) provides a non-invasive assessment of autonomic control of the nervous system over the heart. During pregnancy, the cardiovascular system adapts significantly, affecting HRV and hemodynamics. Studying the relationship between HRV and hemodynamic changes is critical to understanding and monitoring cardiovascular health during pregnancy and postpartum, and predicting potential complications.",[91,92,93],"Pregnancy Related","Heart Rate Variation (HRV)","Hemodynamics","2026-02-12",{"date":69,"type":39},{"date":97,"type":39},"2025-05-19",{"date":99,"type":20},"2027-12-15",{"name":45,"class":46},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":55,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":122,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},"100605106","optical-diagnosis-of-neoplasia-using-artificial-intelligence-100605106","NCT07158203","Optical Diagnosis of Neoplasia Using Artificial Intelligence","Assistance for Optical Diagnosis of Neoplasia Using Artificial Intelligence (FAIR Study)","FAIR","Endoscopists who meet the following inclusion\u002Fexclusion criteria Inclusion criteria\n\n* Endoscopists experienced with more than 100 colonoscopies. Exclusion criteria\n* Endoscopists who are involved in the development of the protocol of the present study.\n\nInclusion and exclusion criteria for the study videos. Inclusion criteria.\n\n* Videos with a duration of 15 seconds including both WL and NBI.\n* Videos with diminutive polyps with confirmed pathology. Exclusion criteria.\n* Videos with no clear image of the polyps.\n* Videos with more than one polyp on-screen.\n* Inflammatory bowel disease\n* Polyposis\n* Hereditary colorectal disease\n* Videos which CADx cannot provide sufficient number of outputs.",{"count":110,"type":20},70,[23],"Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI. Psychological interventions like cognitive forcing, such as delaying CADx suggestions, may improve human-AI interaction by fostering critical assessment. However, their impact on patient-important outcomes remains unexplored.\n\nThe investigators will conduct an ex-vivo randomized study with 70 endoscopists assessing 100 polyp videos (≤5 mm) using a CADx tool (GI Genius, Medtronic). Participants will be randomized to either:\n\n* Intervention group: CADx suggestions will be shown in the last 3 seconds of the 15 second polyp video.\n* Control group: CADx suggestions will be shown in real-time throughout the playback of the 15 second polyp video.\n\nThe primary endpoint is sensitivity for high-confidence neoplasia detection, with secondary endpoints assessing endoscopists' reliance on AI.\n\nCADx systems on the market function in various ways, such as real-time, delayed, or on-demand diagnosis. Our study aims to inform users and manufacturers whether cognitive forcing through delayed CADx suggestions enhances human-AI interaction, leading to improved clinical outcomes.",[114,115,116,117,118,119,120,121],"Polyps Colorectal","Colonoscopy","Optical Biopsy","Colorectal Cancer Control and Prevention","Colorectal Cancer Screening","Behavior Change","Psychological Factors","Psychological Intervention",[123,124,125,126,127,128],"behaviour","optical biopsy","colonoscopy","CADx system","colorectal polyps","psychological intervention","2025-08-28",{"date":131,"type":39},"2025-09-05",{"date":133,"type":20},"2025-09",{"date":135,"type":20},"2025-12",{"name":45,"class":46},2,{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":145,"enrollmentInfo":146,"targetDuration":4,"studyType":21,"phases":148,"briefSummary":149,"conditions":150,"keywords":155,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":47},"100592013","impact-of-a-perioperative-physical-exercise-and-respiratory-physiotherapy-program-on-the-patient-undergoing-bariatric-surgery-100592013","NCT06987903","Impact of a Perioperative Physical Exercise and Respiratory Physiotherapy Program on the Patient Undergoing Bariatric Surgery","CAPS-OB","Inclusion Criteria:\n\n* Patients undergoing bariatric surgery at the General and Digestive Surgery Department of the Álvaro Cunqueiro Hospital in Vigo.\n* Be over 18 and under 69 years old.\n* Sign the informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Patient's refusal to enter the study.\n* Inability to comprehend participation in a study.\n* Urgent interventions.\n* Patients undergoing combined surgery with another surgical service.\n* Patients who cannot read and write or are dependent on a legal representative.\n* Patients on treatment for diabetes with GLP-1 agonists (glucagon-like peptide type 1 agonists) and\u002For SGLT2 inhibitors (sodium-glucose cotransporter type 2 inhibitors) whose dose is not stable in the last 3 months.","69 Years",{"count":147,"type":20},132,[23],"The goal of this clinical trial is to see the impact of a physical exercise programme and respiratory physiotherapy before and after bariatric surgery in obese patients. The main questions it aims to answer are:\n\nCould it help to avoid decompensation of underlying diseases? Could it reduce the risks associated with the intervention and the number of adverse effects during the postoperative period? Could it reduce the number of patients and encourage early discharge? How does exercise affect epigenetics in obese patients undergoing bariatric surgery? Can we correlate epigenectic markers obtained from tissue obtained by invasive procedures such as fat or muscle to those obtained by non-invasive methods such as blood and saliva samples? How does exercise affect the hepatic tissue in obese patients undergoing bariatric surgery? And are the any predictive markers in pre-exercise samples that can correlate with the evolution of liver diseases such asl NALFD or NASH?\n\nResearchers will compare one group of subjects performing the exercise programme and respiratory physiotherapy and anoher group performing the normal activities of routine clinical practice.\n\nParticipants, who are on the surgical waiting list for bariatric surgery, will be assigned to one of the two groups. Participants in group 2 will follow the normal procedure before and after surgery. Participants in group 1 will be asked to do a exercise programme and respiratory physiotherapy before and after surgery.",[151,152,153,154],"Bariatric Surgery and Physical Activity","Obesity\u002FTherapy","Bariatric Surgery Complications","Bariatric Patients",[156,157,158,159],"Bariatric surgery","Obesity","Respiratory physiotherapy","Exercise programme","2025-08-27",{"date":162,"type":39},"2025-09-04",{"date":164,"type":39},"2025-05-07",{"date":166,"type":20},"2026-09-07",{"name":45,"class":46},{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":175,"targetDuration":4,"studyType":21,"phases":177,"briefSummary":178,"conditions":179,"keywords":181,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":4},"100555657","efficacy-of-the-e-motional-training-program-for-improving-social-cognition-in-people-with-dual-pathology-in-a-clinical-and-prison-environment-100555657","NCT06514937","Efficacy of the E-motional Training Program for Improving Social Cognition in People With Dual Pathology in a Clinical and Prison Environment","Efficacy of the E-motional Training Program for Improving Social Cognition in People With Dual Pathology in a Clinical and Prison Environment: Neuropsychological and Proteomic Study","Inclusion Criteria:\n\n* Patients diagnosed with dual pathology according to DSM-5 diagnosed by an expert clinician.\n* Have the capacity to consent (competence).\n* Read the project information sheet and sign the informed consent.\n* Age\\>18 years-old\n\nExclusion Criteria:\n\n* Illiterate\n* History of moderate or severe neurological pathology (TBI, stroke, etc.),\n* Current acute psychiatric process\n* Abstinence of less than 15 days,\n* Advanced cognitive impairment that does not allow evaluation.\n* Have participated in another similar study",{"count":176,"type":20},250,[23],"Drug use, substance-related disorders (SUD), other addictive behaviors, or, from a broader perspective, dual pathology, are problems of enormous socio-health impact that still require a great research effort to improve diagnostic and therapeutic procedures employed in healthcare practice.\n\nSince addictive behaviors have been consistently associated with the presence of alterations in cognitive and executive functions, it is necessary to be able to detect, evaluate, and have specific therapies for these dysfunctions and investigate, among other issues, the role they play in the onset and course of evolution. After implementing neuropsychological evaluation techniques for diagnostic improvement, the search addresses procedures that allow working on cognitive and executive deficits as a specific therapeutic target.\n\nIn a previous project, the investigators studied the presence of social cognition (SC) dysfunctions in a clinical sample of patients treated in drug addiction care facilities. The investigators evaluated the therapeutic efficacy of the ET® program in those who presented difficulties in SC and analyzed molecular patterns in saliva that could be associated with SC dysfunctions and predict therapeutic response. The ET® program is an online self-training program for SC rehabilitation that includes modules for emotion recognition (ER), Theory of Mind (ToM), and attributional style (AS).\n\nTo replicate the RCT carried out in patients with SUD in patients with dual pathology with difficulties in ER or ToM, in addition to including a gender perspective, tele-neuropsychology, and searching for a biomarker or a pattern of them that predicts the patient profile that will benefit from the training, using advanced LC-ESI proteomics techniques. It is also intended to subsequently improve the instrument (ET®) through the implementation of a gender perspective and big data analysis and machine learning, and the introduction of automated user management.\n\nFrom the perspective of the STATE PLAN FOR SCIENTIFIC AND TECHNICAL RESEARCH AND INNOVATION, the project combines clinical and translational research, based on evidence of scientific and technological knowledge, and the use of e-health enabling technologies in the area of Health Services. Health for people with dual pathology, with special attention to the gender perspective.",[180],"Social Behavior",[182],"dual pathology","2024-07-25",{"date":185,"type":39},"2024-07-26",{"date":187,"type":20},"2024-09",{"date":189,"type":20},"2026-06",{"name":45,"class":46},{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":4,"eligibilityCriteria":197,"healthyVolunteers":55,"sex":16,"minAge":198,"maxAge":199,"enrollmentInfo":200,"targetDuration":4,"studyType":21,"phases":202,"briefSummary":203,"conditions":204,"keywords":206,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":47},"100436739","polyprev-study-to-compare-fecal-immunochemical-test-with-endoscopic-surveillance-after-advanced-adenoma-resection-in-fecal-immunochemical-test-colorectal-cancer-screening-programs-100436739","NCT04967183","Polyprev: Study to Compare Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs.","Polyprev Study: Randomized, Multicenter, Controlled Trial Comparing Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs.","Inclusion Criteria:\n\n1. Individuals aged 50 to 65 years.\n2. Individuals with at least one advanced adenoma (tubulovillous or villous histology, high grade dysplasia or ≥ 10mm), and \u002F or at least three non-advanced adenomas detected and resected completely within the population-based CRC screening program.\n\nExclusion Criteria:\n\n1. Personal history of CRC.\n2. Colonic lesion ≥10mm resected without histological diagnosis.\n3. More than 10 adenomas in baseline colonoscopy.\n4. Serrated polyposis syndrome.\n5. Two or more first-degree relatives with CRC.\n6. Hereditary predisposition to CRC.\n7. Relevant comorbidity with life expectancy inferior to 5 years.\n8. Colonoscopy with incomplete mucosal examination.\n9. Incomplete resection of baseline lesions.\n10. Non-acceptance after reading the informed consent.","50 Years","65 Years",{"count":201,"type":20},3788,[23],"Colorectal cancer (CRC) screening programs have been implemented to reduce the burden of the disease. When an advanced colonic lesions is detected, it is recommended to perform endoscopic surveillance with different intervals between explorations. Although the reduction in CRC incidence, endoscopic surveillance is producing a considerable increase in the number of colonoscopies. However, participation in CRC screening programs based on the fecal immunochemical test (FIT) could be a non inferior alternative to endoscopic surveillance.\n\nBased on this hypothesis, the research group have designed a randomized clinical trial within the population CRC screening programs to compare FIT surveillance to endoscopic surveillance in patients with advanced lesions resected.",[205],"Colorectal Cancer",[207,208,209,210,211],"Screening program","Endoscopic surveillance","Fecal immunochemical test","Mediterranean diet","Physical activity","2024-02-26",{"date":214,"type":39},"2024-02-28",{"date":216,"type":39},"2022-06-01",{"date":218,"type":20},"2035-06",{"name":45,"class":46},""]