[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"GCS Ramsay Santé pour l'Enseignement et la Recherche\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":540},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,74,0,25,[9,40,66,87,109,132,157,178,201,225,245,267,286,305,315,338,360,381,402,421,440,460,480,498,519],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100053542","early-maladaptive-schemas-in-french-health-care-professionals-with-burn-out-100053542",false,"NCT06104202","Early Maladaptive Schemas in French Health Care Professionals With Burn Out","Early Maladaptive Patterns as Markers of Vulnerability and Targets for Therapeutic Intervention in Burned-out Healthcare Professionals","SEMBO","Inclusion Criteria:\n\n* Age ≥ 18 years ;\n* State of burnout (at least one of the 3 dimensions of the Maslach Burnout Inventory) for care professionals and non-professionals in a state of burnout and absence of a state of burnout for the group of care professionals without a state of burnout;\n* Membership of a social security scheme;\n* Patient having been informed and having given his\u002Fher oral non-opposition.\n\nExclusion Criteria:\n\n* Characterised psychiatric pathology pre-existing the burn out state for the burn out groups and characterised psychiatric pathology for the no burn out group;\n* Participation in another clinical trial, or in a period of exclusion from another clinical trial;\n* Participant under guardianship, curatorship or deprived of liberty.","ALL","18 Years",{"count":21,"type":22},208,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to compare the profiles and domains of maladaptive early schemas in care professionals with burnout symptoms with care professionals without burnout symptoms and with care non-professionals with burnout symptoms.",[26],"Burn Out","RECRUITING","2026-07-09",{"date":30,"type":31},"2026-07-13","ACTUAL",{"date":33,"type":31},"2024-04-09",{"date":35,"type":22},"2026-12-31",{"name":37,"class":38},"GCS Ramsay Santé pour l'Enseignement et la Recherche","OTHER",1,{"id":41,"slug":42,"hasResults":12,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":39},"100598834","phase-3-efficacy-and-safety-of-intravenous-lidocaine-versus-placebo-in-patients-receiving-morphine-rachi-analgesia-100598834","NCT07076641","Efficacy and Safety of Intravenous Lidocaine Versus Placebo in Patients Receiving Morphine-rachi Analgesia","Phase III, Randomized, Double-blind Study to Assess the Efficacy and Safety of Intravenous Lidocaine Versus Placebo in Patients Receiving Analgesic Morphine Rachi Anesthesia for Major Digestive or Abdominal Surgery by Laparotomy.","LIDORACHI","Inclusion Criteria:\n\n* Age ≥ 18 years;\n* Major digestive or abdominal surgery (pancreatic, hepatic, colorectal, gynecological, esophageal, gastric, duodenal, small intestine...);\n* Scheduled surgery;\n* Laparotomy;\n* Patient in agreement with morphine rachi anesthesia;\n* Social security affiliation;\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Emergency surgery;\n* Contraindication to non-steroidal anti-inflammatory drugs: history of gastro duodenal ulcer, renal failure from stage 3 A or higher;\n* History of bradycardia and\u002For known conduction disorder (atrioventricular block) \u002F Pacemaker ;\n* Unstable coronary ;\n* Myocardial infarction \\\u003C6 months;\n* Severe cardiocirculatory insufficiency;\n* Severe hepatic insufficiency;\n* Allergy to morphine ;\n* Allergy to lidocaine;\n* Rhythm disorders at risk of sudden death (e.g. Brugada syndrome);\n* Flecaine as usual treatment;\n* Chronic pain with level II or III analgesics;\n* Gabapentinoids: pregabalin (Lyrica), gabapentin;\n* Drug addiction and substitute drugs;\n* Epileptic disorders ;\n* Myasthenia gravis;\n* Creatinine clearance below 10 mL\u002Fmin;\n* Hypokalemia, hypoxia or acid-base disorders;\n* Patient participating in another clinical trial, or in a period of exclusion from another clinical trial;\n* Inability to understand study information (due to linguistic, psychological, cognitive or literacy problems);\n* Women who are or may become pregnant\\* (of childbearing age, without effective contraception) or who are breast-feeding;\n* Patient deprived of liberty, under guardianship or unable to give consent.",{"count":49,"type":22},76,"INTERVENTIONAL",[52],"PHASE3","The purpose of this study is to evaluate the superiority of IV lidocaine combined with morphine spinal anesthesia versus placebo combined with morphine spinal anesthesia, in reducing postoperative morphine consumption at 48 hours, in patients undergoing major digestive or abdominal surgery by laparotomy.",[55,56],"Digestive System Disease","Surgery","NOT_YET_RECRUITING","2026-06-30",{"date":60,"type":31},"2026-07-01",{"date":62,"type":22},"2026-07",{"date":64,"type":22},"2027-07-30",{"name":37,"class":38},{"id":67,"slug":68,"hasResults":12,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":50,"phases":76,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":86,"locationsCount":39},"100563885","evaluation-of-the-fundoplicature-of-the-excluded-stomach-post-omega-bypass-100563885","NCT06621979","Evaluation of the Fundoplicature of the Excluded Stomach Post Omega Bypass","Evaluation of Post-Omega Bypass Excluded Stomach Fundoplication to Treat Disabling Gastroesophageal Reflux Disease Resistant to Medical Treatment and Requiring Surgery","FEE-RGOIC","Inclusion Criteria:\n\n* Age ≥ 18 years;\n* Patient operated for one anastomosis gastric bypass followed by Fundoplicature with stomach excluded for disabling gastroesophageal reflux requiring surgery within 2 years prior to inclusion;\n* Patient in failure of medical treatment;\n* Weight loss greater than 50% of excess weight;\n* Patient with preoperative objective investigations (gastrojejunal fibroscopy, ph-impedancemetry, abdominal CT scan) of gastroesophageal reflux disease;\n* Patient able to understand study-related information and to complete quality-of-life questionnaires in the opinion of the investigator;\n* Patient willing to accept study evaluations;\n* For women of childbearing age, effective contraception for the duration of the study or negative blood pregnancy test;\n* Patient has been informed and has given free, informed and written consent.\n\nExclusion Criteria:\n\n* Patient with conversion from one anastomosis gastric bypass to Y bypass for disabling gastroesophageal reflux requiring surgery;\n* Patient with concomitant hiatal hernia correction for one anastomosis gastric bypass ;\n* Patient with secondary one anastomosis gastric bypass ;\n* Patient with a deregulated diet;\n* Patient under legal protection, or deprived of liberty by judicial or administrative decision;\n* Patient unable to understand study information for linguistic, psychological, cognitive or other reasons;\n* Women who are or may become pregnant, of childbearing age, without effective contraception or who are breast-feeding;\n* Patient participating in another clinical trial, or in a period of exclusion from another clinical trial that could interfere with the results of the present study;\n* Patient not covered by a social security scheme.",{"count":75,"type":22},17,[77],"NA","The purpose of this study is to evaluate the efficacy of fundoplication with stomach excluded in the suppression of disabling gastroesophageal reflux requiring surgery in patients who have undergone one anastomosis gastric bypass, with complete objective evaluation of reflux.",[80],"Bypass, Gastric",{"date":82,"type":31},"2026-07-02",{"date":84,"type":31},"2025-11-24",{"date":35,"type":22},{"name":37,"class":38},{"id":88,"slug":89,"hasResults":12,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":94,"targetDuration":4,"studyType":50,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":39},"100644597","assessment-of-the-benefits-of-psychological-care-before-anterior-cruciate-ligament-surgery-of-the-knee-clipper-100644597","NCT07671430","Assessment of the Benefits of Psychological Care Before Anterior Cruciate Ligament Surgery of the Knee (CLIPPER)","CLIPPER","Inclusion Criteria:\n\n* Patient having signed the consent form for participation in the study\n* Patient scheduled for first-line outpatient ACL reconstruction surgery\n* Patient with a score \\>30 on the SFQ questionnaire (which assesses fear of surgery)\n* Patient with the ability to connect to the internet and follow a teleconsultation on a screen\n\nExclusion Criteria:\n\n* Surgical history of the operated knee\n* History of psychiatric disorders and\u002For regular use of psychotropic medication\n* Regular use of opioid medication\n* Mental disability or any other reason that may hinder understanding or strict adherence to the protocol\n* Patient not affiliated with the French social security system\n* Patient under legal protection, guardianship or curatorship\n* Pregnant, breastfeeding or childbearing women without effective contraception\n* A patient who is already enrolled in another therapeutic study protocol or who has participated in another trial within the past three months",{"count":95,"type":22},126,[77],"The primary objective of this study is to assess the impact of a preoperative psychological consultation on postoperative pain in anxious patients undergoing primary anterior cruciate ligament reconstruction surgery.",[99,100],"Anxiety","Ligament Reconstruction Surgery","2026-06-22",{"date":103,"type":31},"2026-06-26",{"date":105,"type":31},"2026-05-07",{"date":107,"type":22},"2027-10",{"name":37,"class":38},{"id":110,"slug":111,"hasResults":12,"nctId":112,"briefTitle":113,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":116,"targetDuration":4,"studyType":50,"phases":118,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":129,"leadSponsor":131,"locationsCount":39},"100644356","assessment-of-smi-superb-microvascular-imaging-for-characterising-the-endocystic-material-of-papillary-intraductal-mucinous-pancreatic-tumours-pimpt-100644356","NCT07663734","Assessment of SMI (Superb Microvascular Imaging) for Characterising the Endocystic Material of Papillary Intraductal Mucinous Pancreatic Tumours (PIMPT)","ENDOKYSMILE","Inclusion Criteria:\n\n* Patient referred for an endoscopic ultrasound assessment of a PIMPT\n* Patient with endocystic material of undetermined nature measuring 3 mm or more\n* Patient registered with or covered by the social security scheme\n* Patient who speaks French\n* Patient who has signed an informed consent form\n\nExclusion Criteria:\n\n* Patient whose lesion meets the criteria for malignancy (tissue mass, metastases, ascites, vascular infiltration)\n* Patient for whom Sonovue is contraindicated\n* Pregnant woman\n* Vulnerable patient: an adult under guardianship, curatorship or other legal protection, or deprived of their liberty by a judicial or administrative decision\n* Patient admitted to hospital without consent",{"count":117,"type":22},60,[77],"There are many types of pancreatic cysts, and papillary intraductal mucinous pancreatic tumours (PIMPTs) are among the most common.\n\nPIMPTs carry a risk of progressing to a cancerous lesion. To assess this risk, the key examination involves performing an endoscopic ultrasound combined with an injection of a contrast agent called Sonovue.\n\nSuperb Microvascular Imaging (SMI) is a new ultrasound modality that enables the analysis of PIMPTs without the need for a Sonovue injection.\n\nThe Mermoz Endoscopy Centre will be equipped with an ultrasound console enabling SMI to be performed during an endoscopic ultrasound examination.\n\nThis technology is now available on the new EUS Aplio i800 console (Canon-Olympus), which bears the CE mark.\n\nTo date, no data have been published on the potential of SMI for analysing a PIMPT. This is why this clinical investigation is being conducted",[121],"Papillary and Mucinous Intraductal Tumours of the Pancreas",[123,124],"papillary and mucinous intraductal tumours of the pancreas","SMI","2026-06-17",{"date":127,"type":31},"2026-06-23",{"date":62,"type":22},{"date":130,"type":22},"2028-01",{"name":37,"class":38},{"id":133,"slug":134,"hasResults":12,"nctId":135,"briefTitle":136,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":139,"sex":18,"minAge":19,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":50,"phases":143,"briefSummary":144,"conditions":145,"keywords":147,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":39},"100641984","assessment-of-neuro-k-starts-following-primary-anterior-cruciate-ligament-acl-reconstruction-100641984","NCT07659613","Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction","NEURO-K-STARTS","Inclusion Criteria (patients):\n\n* Patient who has undergone primary ACL reconstruction at least 6 months ago\n* Patient who has undergone an isokinetic strength test, the results of which do not indicate any contraindications to performing a functional test\n* Patient who has resumed performing horizontal jumps under the supervision of a healthcare professional\n* Patient with no history of surgery on the joints of the contralateral leg\n* Patient enrolled in or covered by a social security scheme\n* French-speaking patient who has signed an informed consent form\n\nExclusion Criteria (patients):\n\n* Patient with a history of ligament surgery on the affected or contralateral knee\n* Patient with a BMI \\\u003C 18.5 or \\> 30\n* Patient who is professional athlete\n* Patient with severe associated conditions (neurological, connective tissue disorders, congenital diseases)\n* Patient with colour blindness\n* Patient with multi-ligament injury or associated osteotomy\n* Patient enrolled in another study whose procedures may interfere with this study\n* Protected patient: adults under guardianship, curatorship or other legal protection, or deprived of their liberty by judicial or administrative decision\n\nInclusion Criteria (healthy volunteers):\n\n* Subject with no history of surgery on the joints of either leg\n* Subject who is member of or beneficiary of a social security scheme\n* French-speaking subject who has signed an informed consent form\n\nExclusion Criteria (healthy volunteers):\n\n* Subject with a BMI \\\u003C 18.5 or \\> 30\n* Subject who is professional athlete\n* Subject with severe associated conditions (neurological, connective tissue disorders, congenital diseases)\n* Subject with colour blindness\n* Subject with multi-ligament deficiency or associated osteotomy\n* Subject enrolled in another study whose procedures may interfere with this study\n* Subject under legal protection: adults under guardianship, curatorship or other legal protection, or deprived of their liberty by judicial or administrative decision",true,"35 Years",{"count":142,"type":22},144,[77],"Anterior cruciate ligament (ACL) reconstruction is the major treatment option for ACL injuries. Despite this, recurrence rates are high. Half of all recurrences occur within 8 months of reconstruction, and 70% within the first 6 months after return to sport (RTS). The decision to RTS is therefore a critical one, as returning too early can increase the risk of recurrence, whilst a delayed return delays a return to pre-injury performance levels.\n\nTo guide this decision-making process, objective data is required to determine fitness for RTS. This is why the K-STARTS (Knee Safety Athletic Return to Sport) was developed. It is a composite test comprising functional and psychological assessments that enable the calculation of an overall score used to determine the functional recovery of the knee six months after ACL reconstruction.\n\nCurrently, functional tests are limited to measuring physical performance, whereas athletes often manage complex visuospatial processing whilst performing physically. It is therefore necessary to develop clinical tests that integrate neurocognitive and physical functions in order to better simulate the sporting challenges that lead to injury and thus improve preparation for RTS NEURO-K-STARTS is a battery of functional tests based on three standard horizontal jump tests from the K-STARTS, supplemented by four neurofunctional tests.\n\nNo evaluation of the NEURO-K-STARTS in patients undergoing primary ACL reconstruction has been published. This is why this research is set up.",[146],"ACL - Anterior Cruciate Ligament Rupture",[148,137,149],"K-STARTS","ACL rupture","2026-06-15",{"date":101,"type":31},{"date":153,"type":22},"2026-09",{"date":155,"type":22},"2029-02",{"name":37,"class":38},{"id":158,"slug":159,"hasResults":12,"nctId":160,"briefTitle":161,"officialTitle":161,"acronym":162,"eligibilityCriteria":163,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":164,"enrollmentInfo":165,"targetDuration":4,"studyType":50,"phases":167,"briefSummary":168,"conditions":169,"keywords":170,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":174,"startDateStruct":175,"completionDateStruct":176,"leadSponsor":177,"locationsCount":39},"100641760","assessment-of-electromyographic-activity-in-the-quadriceps-and-hamstrings-of-the-operated-limb-versus-the-unaffected-limb-in-patients-who-have-undergone-acl-surgery-with-and-without-post-operative-ami---an-exploratory-study-100641760","NCT07659561","Assessment of Electromyographic Activity in the Quadriceps and Hamstrings of the Operated Limb Versus the Unaffected Limb in Patients Who Have Undergone ACL Surgery, With and Without Post-operative AMI - an Exploratory Study","AMIMYO","Inclusion Criteria:\n\n* Patient who has undergone ACL surgery at least 3 weeks ago\n* Patient with no severe knee inflammation: stroke test ≤ 1+ and pain ≤ 3\u002F10 (EN) at rest\n* Patient with a Tegner score ≥ 5\n* Patient with a Marx score ≥ 8\n* Patient with or without a diagnosis of subjective AMI (Sonnery-Cottet et al. classification)\n* French-speaking patients who do not object to the use of their data\n\nExclusion Criteria:\n\n* Patient with a previous injury or surgery to the same or opposite knee\n* Patient with a multi-ligament injury\n* Patient with an AMI \\> grade 2b (Sonnery-Cottet et al. classification)\n* Patient with a BMI \\> 30\n* Pregnant or breastfeeding woman\n* Patient with previous or current neurological and cardiovascular disorders or diseases\n* Patient under legal protection: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision","45 Years",{"count":166,"type":22},40,[77],"Traumatic injuries to the knee joint, such as an anterior cruciate ligament tear, can compromise the ability of the muscle at the front of your thigh-known as the quadriceps-to contract voluntarily, despite the anatomical integrity of the nerve and muscle structures responsible for contraction. This phenomenon, commonly known as 'arthrogenic motor inhibition' (AMI), is a major limiting factor for recovery and rehabilitation following an anterior cruciate ligament tear, as well as a potential cause of functional disability if left undiagnosed and untreated. Indeed, motor inhibition that persists during the early months of rehabilitation could lead to under-activation of the quadriceps and over-activation of the hamstrings (the muscles at the back of your thigh).\n\nIt is of interest to assess, during the rehabilitation phase, the contraction capacity of the various quadriceps and hamstring muscles in the operated limb compared with the unaffected limb in patients who have undergone anterior cruciate ligament surgery and who experience post-operative motor inhibition, and in patients who have undergone anterior cruciate ligament surgery but do not experience post-operative motor inhibition. This is why this study has been initiated.",[146],[149,171,172,173],"AMI","electromyography","thigh",{"date":101,"type":31},{"date":153,"type":22},{"date":107,"type":22},{"name":37,"class":38},{"id":179,"slug":180,"hasResults":12,"nctId":181,"briefTitle":182,"officialTitle":182,"acronym":183,"eligibilityCriteria":184,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":185,"enrollmentInfo":186,"targetDuration":4,"studyType":50,"phases":188,"briefSummary":189,"conditions":190,"keywords":191,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":39},"100641387","intraoperative-analysis-of-knee-kinematics-during-acl-reconstruction---an-exploratory-study-100641387","NCT07655726","Intraoperative Analysis of Knee Kinematics During ACL Reconstruction - an Exploratory Study","CINEGEN","Inclusion Criteria:\n\n* Patient, male or female, aged between 18 and 40\n* Patient eligible for ACL and LAL reconstruction\n* Patient who is member of or covered by a social security scheme\n* Patient who speaks French and has signed an informed consent form\n\nExclusion Criteria:\n\n* Patient with a contraindication to MRI\n* Patient with osteoarthritis of the joint\n* Patient with a BMI \\> 30\n* Patient with history of trauma or previous knee surgery\n* Patient with knee trauma other than a sprain\n* Patient under legal guardianship: an adult under guardianship, curatorship or other legal protection, or deprived of liberty by judicial or administrative order\n* Pregnant or breastfeeding woman","40 Years",{"count":187,"type":22},30,[77],"Reconstruction of anterior cruciate ligament (ACL) is a common procedure in orthopaedic surgery, aimed at restoring stability to your knee. This procedure involves performing an anterior cruciate ligament (ACL) graft and an anterolateral ligament (ALL) graft.\n\nDespite technological advances and improvements in surgical techniques, failure rates remain high. In this context, a better understanding of knee movements (the position of the femur and tibia, as well as the ligaments) during flexion whilst reconstructing your ACL could improve the precision of reconstructions and reduce the long-term failure rate.\n\nUsing a surgical navigation system, it is possible to record data on the positioning of the femur and tibia during flexion and extension. This type of morpho-functional analysis of knee kinematics during ACL reconstruction has never been carried out before.",[146],[149,192],"Knee cinematics","2026-06-13",{"date":195,"type":31},"2026-06-18",{"date":197,"type":22},"2027-07",{"date":199,"type":22},"2028-03",{"name":37,"class":38},{"id":202,"slug":203,"hasResults":12,"nctId":204,"briefTitle":205,"officialTitle":205,"acronym":206,"eligibilityCriteria":207,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":208,"enrollmentInfo":209,"targetDuration":4,"studyType":50,"phases":211,"briefSummary":212,"conditions":213,"keywords":215,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":219,"startDateStruct":220,"completionDateStruct":221,"leadSponsor":223,"locationsCount":224},"100641218","comparison-of-minced-cartilage-implantation-versus-microfracture-for-acetabular-chondral-lesions-due-to-fai-femoro-acetabular-impingement-100641218","NCT07657871","Comparison of Minced Cartilage Implantation Versus Microfracture for Acetabular Chondral Lesions Due to FAI (Femoro-acetabular Impingement)","CARTIFRAC","Inclusion Criteria:\n\n* Patient, male or female, aged 18-50 years old;\n* Patient with an acetabular chondral lesion due to FAI, characterised as Beck class 4 or 5, measuring 1-6 cm2;\n* Patient with Tönnis grade 0-2;\n* Patient who signed the informed consent form and is willing to comply with the protocol requirements based on the investigator's judgment;\n* Patient affiliated with a social security scheme;\n* Patient able to answer questionnaires and to communicate freely in French\n\nExclusion Criteria:\n\n* Patient with prior ipsilateral hip surgery;\n* Patient with borderline or frank hip dysplasia (lateral centre edge angle \\\u003C25º);\n* Patient with hyperlaxity (Beighton score \\>7);\n* Patient with any concomitant disease or disorder which, in the opinion of the investigator, may put the patient at risk or may influence the result of the study;\n* Patient that is pregnant or breastfeeding;\n* Patient with protected status under articles L1121-6, LL121-8 and L1122-2 of the French Public Health Code;\n* Patient who cannot comply with the protocol requirements based on the investigator's judgment","50 Years",{"count":210,"type":22},180,[77],"A femoroacetabular impingement (FAI) is an abnormal contact between pelvis and the neck of femur. It occurs particularly when patient bends his hip and causes damage to the cartilage. In the long term, FAI can lead to the development of osteoarthritis (cartilage destruction) and may require a total hip replacement (THR).\n\nSurgery to treat cartilage damage in the hip aims to maintain joint function and delay the onset of osteoarthritis. Microfracture remains the most commonly used treatment for cartilage lesions. It is a surgical technique for repairing articular cartilage that works by creating tiny fractures in the bone, which in turn stimulate the growth of new cartilage.\n\nCartilage autografting is a promising alternative to microfracture, offering good results in the knee joint. Cartilage autografting involves the use of autologous cartilage tissue (taken from patient body), which is harvested, ground up and reimplanted in a single surgical procedure to promote the growth of new cartilage and repair.\n\nThe published literature lacks large-scale studies comparing autologous cartilage transplantation with traditional joint-preserving surgeries, such as microfracture. This is the reason why this study is set up.",[214],"Femoro-acetabular Impingement (FAI)",[216,217,218],"FAI","Minced cartilage implantation","microfracture",{"date":195,"type":31},{"date":62,"type":22},{"date":222,"type":22},"2031-06",{"name":37,"class":38},2,{"id":226,"slug":227,"hasResults":12,"nctId":228,"briefTitle":229,"officialTitle":229,"acronym":230,"eligibilityCriteria":231,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":50,"phases":233,"briefSummary":234,"conditions":235,"keywords":237,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":239,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":39},"100641512","assessment-of-the-usefulness-of-smi-superb-vascular-imaging-for-the-characterisation-of-pancreatic-cystic-tumours-imakyst-100641512","NCT07657884","Assessment of the Usefulness of SMI (Superb Vascular Imaging) for the Characterisation of Pancreatic Cystic Tumours (IMAKYST)","IMAKYST","Inclusion Criteria:\n\n* Patient referred for confocal microscopy (nCLE) assessment of a pancreatic cyst of unknown origin\n* Patient with a cyst measuring more than 15 mm in diameter and at least one cyst cavity measuring ≥ 5 mm (to allow nCLE to be performed)\n* Patient registered with or covered by the National Health Service\n* French-speaking patient who has signed an informed consent form\n\nExclusion Criteria:\n\n* Patient with calcifying chronic pancreatitis\n* Presence of a communication with the main pancreatic duct on MRI or endoscopic ultrasound\n* Patient whose lesion meets criteria for malignancy (tissue mass, metastases, ascites, vascular infiltration)\n* Patient with a contraindication to endoscopic ultrasound-guided puncture (haemostatic disorder)\n* Patient with a known allergy to fluorescein (used in nCLE)\n* Pregnant woman\n* Patient under legal guardianship: adults under guardianship, curatorship or other legal protection, or deprived of their liberty by judicial or administrative order\n* Hospitalised patient without consent",{"count":117,"type":22},[77],"A cystic lesion is an abnormal cavity formed within tissue or an organ, which may contain a liquid, semi-solid or gaseous substance.\n\nThere are different types of pancreatic cystic lesions: lesions that may become cancerous and completely benign lesions that do not require monitoring, such as serous cystadenomas (SCs) and pseudocysts.\n\nDiagnostic difficulties mean that one in three patients with a SC undergoes unnecessary surgery with significant morbidity and mortality (risk of death). Currently, needle-based confocal laser endomicroscopy (nCLE) is the gold standard technique for the diagnosis of SC.\n\nSC is a lesion characterised by an extensive network of small blood vessels present in all the cyst walls and throughout the cyst's peripheral capsule. SMI (Superb Vascular Imaging) is a new ultrasound mode that improves the visibility of blood flow in the vessels without the injection of contrast medium (a diagnostic agent used for certain medical imaging examinations, most often administered intravenously), unlike nCLE.\n\nThe Mermoz Endoscopy Centre will be equipped with an ultrasound console enabling SMI to be performed during an echoendoscopy examination. This technology is now available on the new EUS Aplio i800 console (Canon-Olympus), which is CE marked.\n\nTo date, no data has been published on the potential of SMI to characterise and diagnose CS. This is why this clinical investigation is being conducted.",[236],"Serous Cystadenoma",[124,238],"serous cystadenoma",{"date":195,"type":31},{"date":241,"type":31},"2026-05-15",{"date":243,"type":22},"2027-11-30",{"name":37,"class":38},{"id":246,"slug":247,"hasResults":12,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":251,"eligibilityCriteria":252,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":253,"targetDuration":255,"studyType":23,"phases":4,"briefSummary":256,"conditions":257,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":262,"completionDateStruct":264,"leadSponsor":266,"locationsCount":39},"100641750","patient-satisfaction-safety-and-efficacy-of-endovenous-laser-treatment-for-saphenous-veins-and-varicose-veins-100641750","NCT07629843","Patient Satisfaction, Safety, and Efficacy of Endovenous Laser Treatment for Saphenous Veins and Varicose Veins","Patient Satisfaction, Safety and Efficacy of Treatment for Saphenous Veins and Varicose Veins Outside the Operating Theater Under Strict Local Anesthesia With 1940nm Endovenous Laser: a Prospective Multicenter Observational Study","IPV-1940","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Endovenous Laser Ablation of a common or recurrent saphenous vein as part of routine care.\n* Clinical, Etiology, Anatomy, Pathophysiology, classification clinical stage.\n* Ability to understand the study objectives and complete questionnaires in French.\n* Patient has been informed and has verbally indicated their non-opposition to participating in the research.\n\nExclusion Criteria:\n\n* Endovenous Laser Ablation not feasible for technical reasons, particularly if the vein is too \"bent\" or there are endoluminal obstacles.\n* Episode of deep vein thrombosis less than 3 months ago or of superficial vein thrombosis less than 6 weeks ago.\n* Active cancer.\n* Geographical distance incompatible with study follow-up, according to the investigator's judgment.\n* Patients currently participating or having participated in research within the previous 3 months.\n* Persons covered by articles L1121-5 to L1121-8 of the French Public Health Code (corresponds to all protected persons: pregnant women, women in labor, breastfeeding mothers, persons deprived of liberty by judicial or administrative decision, persons subject to a legal protection measure).",{"count":254,"type":22},155,"1 Year","The purpose of this study is to evaluate the post-operative patient satisfaction on the treatment of saphenous veins and varicose veins outside the operating theater under strict local anesthesia with a 1940 nm laser via the Venous Treatment Satisfaction Questionnaire early.",[258],"Saphenous Vein Injury","2026-06-12",{"date":261,"type":31},"2026-06-16",{"date":263,"type":22},"2026-06",{"date":265,"type":22},"2028-06",{"name":37,"class":38},{"id":268,"slug":269,"hasResults":12,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":273,"eligibilityCriteria":274,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":275,"targetDuration":4,"studyType":50,"phases":277,"briefSummary":278,"conditions":279,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":281,"startDateStruct":282,"completionDateStruct":283,"leadSponsor":285,"locationsCount":39},"100626606","study-comparing-neoadjuvant-versus-adjuvant-stereotactic-radiotherapy-of-brain-metastases-100626606","NCT07437820","Study Comparing Neoadjuvant Versus Adjuvant Stereotactic Radiotherapy of Brain Metastases","Prospective, Randomized, Multicenter Study Comparing the Efficacy and Tolerance of Neoadjuvant Versus Adjuvant Stereotactic Radiotherapy in the Management of Brain Metastases","NeoSRS","Inclusion Criteria:\n\n* Patients aged 18 years and older;\n* Patients with 1 to 12 brain metastases on preoperative MRI, at least one of which (contrast enhancement of at least 1 cm) is accessible for the most complete possible resection (target lesion);\n* Patients with a Karnofsky performance score of ≥ 70;\n* Patients able to perform neurocognitive tests without assistance;\n* Patients who understand the study and agree to attend all visits;\n* Patients who have signed a written informed consent form;\n* Affiliation with a social security system.\n\nExclusion Criteria:\n\n* Patient who has already been treated with surgery, radiosurgery, and\u002For radiotherapy for the target brain metastasis;\n* Medical contraindication to MRI;\n* Patient with an estimated life expectancy of ≤ 3 months;\n* Patients participating in another clinical trial, or who are in the exclusion period of another clinical trial;\n* Patients unable to complete a self-administered questionnaire;\n* Patients from a vulnerable population.",{"count":276,"type":22},68,[77],"The purpose of this study is to evaluate the local control rate on the target lesion at 6, 12, and 24 months after treatment with neoadjuvant stereotactic radiotherapy (SRS NEO group) compared to standard care, adjuvant stereotactic radiotherapy (POST OP SRS group).",[280],"Brain Metastases, Adult",{"date":150,"type":31},{"date":62,"type":22},{"date":284,"type":22},"2030-06-30",{"name":37,"class":38},{"id":287,"slug":288,"hasResults":12,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":292,"eligibilityCriteria":293,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":294,"targetDuration":4,"studyType":50,"phases":295,"briefSummary":296,"conditions":297,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":299,"startDateStruct":300,"completionDateStruct":302,"leadSponsor":304,"locationsCount":39},"100560494","immersive-sensory-projections-for-hospitalized-patients-100560494","NCT06577870","Immersive Sensory Projections for Hospitalized Patients","Immersive Sensory Projections: Evaluating the Impact of an Immersive Sensory Environment (Visual, Auditory and Olfactory) on Reducing the Overall Discomfort of Patients Hospitalized in the Resuscitation and Continuing Care Units","IHP","Inclusion Criteria:\n\n* Age ≥ 18 years ;\n* Patient hospitalized in intensive care or continuing care unit for an estimated minimum of 48 hours;\n* Patient hospitalized for a medical indication (including in the pre-surgical phase) or in the post-surgical phase;\n* Patient or support person who speaks and understands French, has understood the research procedures and is able to complete the questionnaires;\n* For women of childbearing age (non-menopausal), even for those on contraception: negative pregnancy test (urinary); If positive: completed by a biological test;\n* Patient or trusted support person having been informed and having signed an informed consent form to participate in the study.\n\nExclusion Criteria:\n\n* Deaf or blind patient;\n* Asthmatic patient with background treatment;\n* Epileptic patient or known history of convulsion;\n* Known allergy or intolerance to essential oils or to a component of essential oils;\n* Patient transferred from another intensive care unit;\n* Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision);\n* Breast-feeding or pregnant women;\n* Patient or support person unable to understand information relating to the study (linguistic, psychological, cognitive, etc.);\n* Unconscious patient with no relative or support person present;\n* Homeless patient;\n* Patient with known severe psychiatric illness such as chronic hallucinatory psychosis or paranoid syndrome;\n* Patient participating in or being excluded from another clinical trial;\n* Patient not covered by a social security scheme.",{"count":21,"type":22},[77],"The purpose of this study is to assess the impact of adding three sensory elements (visual, auditory, olfactory) on reducing discomfort in patients hospitalized in the intensive care unit\u002Fcontinuing care unit.",[298],"Hospitalism",{"date":261,"type":31},{"date":301,"type":31},"2025-05-20",{"date":303,"type":22},"2027-01",{"name":37,"class":38},{"id":306,"slug":4,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":307,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":309,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":310,"startDateStruct":311,"completionDateStruct":312,"leadSponsor":314,"locationsCount":39},"100524091",{"count":308,"type":22},273,[26],{"date":150,"type":31},{"date":33,"type":31},{"date":313,"type":22},"2026-12",{"name":37,"class":38},{"id":316,"slug":317,"hasResults":12,"nctId":318,"briefTitle":319,"officialTitle":320,"acronym":321,"eligibilityCriteria":322,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":323,"targetDuration":4,"studyType":50,"phases":325,"briefSummary":326,"conditions":327,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":330,"lastUpdatePostDateStruct":331,"startDateStruct":333,"completionDateStruct":335,"leadSponsor":337,"locationsCount":224},"100586807","infiltration-or-nerve-blocks-in-addition-to-adductor-canal-block-100586807","NCT06920186","Infiltration or Nerve Blocks in Addition to Adductor Canal Block","Comparison of the Benefit of Peripheral Nerve Quadri-block Versus Adductor Canal Block + Surgical Infiltration in Total Knee Arthroplasty","INCA","Inclusion Criteria:\n\n* Adult male or female\n* Patient with signed consent to participate in the study,\n* Patient with uni or bilateral primary gonarthrosis\n* Indication for total knee arthroplasty.\n\nExclusion Criteria:\n\n* History of knee fracture, arthroplasty or osteotomy\n* Known or unknown contraindication to ALR or locoregional anesthesia products\n* Neurological disease, stroke sequelae\n* Mental deficiency or any other reason that may hinder understanding or strict application of the protocol\n* Patient not affiliated to the French social security system\n* Patient under court protection, guardianship or curatorship\n* Pregnant or potentially pregnant women (women of childbearing age without effective contraception)\n* Patient already included in another therapeutic study protocol",{"count":324,"type":22},100,[77],"The aim of this study is to evaluate the analgesic efficacy of this quadruple sensory block compared with the currently recommended procedure (adductor canal block + infiltration).",[328,329],"Gonarthrosis","Total Knee Arthroplasty","2026-06-03",{"date":332,"type":31},"2026-06-05",{"date":334,"type":31},"2026-05-04",{"date":336,"type":22},"2027-06",{"name":37,"class":38},{"id":339,"slug":340,"hasResults":12,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":344,"eligibilityCriteria":345,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":346,"targetDuration":4,"studyType":50,"phases":348,"briefSummary":349,"conditions":350,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":39},"100514428","value-of-capsular-repair-for-latarjet-100514428","NCT05978362","Value of Capsular Repair for Latarjet","Prospective, Multicenter, Randomized Single-blind Study on the Interest of Capsular Repair in the Latarjet Operation","CAP-LATARJET","Inclusion Criteria:\n\n* Patient, male or female, over the age of 18\n* Patient with shoulder instability with risk factors for recurrence (ISIS score \\> 3), requiring surgical stabilization by abutment\n* Affiliated patient or beneficiary of a social security scheme\n* Patient having been informed and having given his free, informed and written consent.\n\nExclusion Criteria:\n\n* Patient with history of surgery for instability of the same shoulder\n* Patient presenting contraindications to the realization of a postoperative scanner\n* Patient whose physical and\u002For psychological health is severely impaired, which according to the investigator may affect the compliance of the study participant\n* Patient participating in another clinical research or in a period of exclusion from another research still in progress at the time of inclusion\n* Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision\n* Pregnant, breastfeeding or parturient woman\n* Patient hospitalized without consent.",{"count":347,"type":22},86,[77],"The purpose of the study is to evaluate the occurrence of osteoarthritis (YES\u002FNO) by radiography.",[351],"Shoulder Pain","2026-05-12",{"date":354,"type":31},"2026-05-13",{"date":356,"type":31},"2023-10-11",{"date":358,"type":22},"2037-12",{"name":37,"class":38},{"id":361,"slug":362,"hasResults":12,"nctId":363,"briefTitle":364,"officialTitle":364,"acronym":365,"eligibilityCriteria":366,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":367,"targetDuration":4,"studyType":50,"phases":369,"briefSummary":370,"conditions":371,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":380,"locationsCount":39},"100640500","comparison-of-analgesic-efficacy-and-impact-on-motor-function-in-knee-replacement-surgery-01-naropeine-tri-block-versus-05-naropeine-ipack-saphenous-block---a-prospective-randomised-trial-100640500","NCT07578688","Comparison of Analgesic Efficacy and Impact on Motor Function in Knee Replacement Surgery: 0.1% Naropeine Tri-block Versus 0.5% Naropeine iPACK Saphenous Block - A Prospective Randomised Trial","ProBlocs","Inclusion Criteria:\n\n* Age \\> 18 years;\n* Patients scheduled for total knee replacement (TKR);\n* ASA (American Society of Anesthesiologists) class 1 to 3;\n* Patient who is able to understand the information relating to the study, read the information leaflet and agree to sign the informed consent form;\n* Enrolment iin the French healthcare system.\n\nExclusion Criteria:\n\n* Patients with an ASA score \\> 3;\n* Patients with a chronic pain condition requiring regular prescription pain relief, such as osteoarthritis, fibromyalgia, neuropathic pain or rheumatoid arthritis;\n* Patients with a major anxiety disorder (APAIS score);\n* Patients with a history of algodystrophy;\n* Pregnant or breastfeeding women;\n* History or evidence of any other clinically significant disorder, condition or disease which, in the investigator's opinion, would pose a risk to patient safety or interfere with the assessment, procedures or completion of the study;\n* Participation in any other clinical trial during the duration of the study;\n* Patients under guardianship or curatorship or subject to deprivation of liberty.",{"count":368,"type":22},120,[77],"Over the last two decades, perioperative analgesia has evolved. Spinal and epidural anaesthesia, once common, have been gradually phased out due to their side effects. The femoral block combined with the sciatic block, possibly with a perineural catheter, is now the gold standard for ensuring prolonged, high-quality analgesia. However, these blocks can cause muscle weakness in the quadriceps, limiting patients' functional recovery.\n\nTo optimise functional rehabilitation, recent techniques favour more distal and selective blocks, such as the adductor canal (saphenous) block and the iPACK, which allow effective anaesthesia to be maintained whilst preserving motor function. However, these blocks do not always guarantee complete analgesia and may require additional blocks.\n\nThe hypothesis of the current study is based on the idea that a proximal block targeting the femoral, obturator and sciatic nerves, administered with a low concentration of naropeine (0.1%), could provide more effective analgesia than a 0.5% saphenous iPACK block, whilst preserving motor function The originality of our approach in the current study lies in the use of dissociative proximal blocks performed with low concentrations of local anaesthetics, aimed at effectively covering the innervation of the knee whilst preserving motor function.\n\nThe expected outcomes of this research are to optimise analgesic management for patients undergoing functional orthopaedic knee surgery, to promote early postoperative walking rehabilitation, to reduce the risk of chronic pain following knee arthroplasty, and to provide evidence to guide anaesthetic and post-surgical rehabilitation practices",[372],"Knee Surgery","2026-05-05",{"date":375,"type":31},"2026-05-11",{"date":377,"type":22},"2026-09-30",{"date":379,"type":22},"2027-12-31",{"name":37,"class":38},{"id":382,"slug":383,"hasResults":12,"nctId":384,"briefTitle":385,"officialTitle":385,"acronym":386,"eligibilityCriteria":387,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":388,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":389,"conditions":390,"keywords":393,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":396,"startDateStruct":398,"completionDateStruct":400,"leadSponsor":401,"locationsCount":39},"100619872","prospective-study-evaluating-the-effectiveness-of-intraoperative-ventilation-for-predicting-postoperative-air-leaks-during-major-lung-resections-by-conventional-or-robotic-thoracoscopy-100619872","NCT07350265","Prospective Study Evaluating the Effectiveness of Intraoperative Ventilation for Predicting Postoperative Air Leaks During Major Lung Resections by Conventional or Robotic Thoracoscopy","NODRAIN","Inclusion Criteria:\n\n* Patient with pulmonary lobectomy or Anatomical segmentectomy with closed chest (conventional or robotic thoracoscopy);\n* Patient affiliated with a health insurance scheme.\n* Person who has not objected to the collection of his\u002Fher data for the purpose of the study.\n\nExclusion Criteria:\n\n* Patient undergoing any type of lung resection by thoracotomy;\n* Patient with a history of thoracic surgery on the same side;\n* Patient with pulmonary fibrosis;\n* Patient from a vulnerable population as defined in Articles L.1121-5 to 8 of the French Public Health Code.\n* Patient undergoing conversion to thoracotomy;\n* Patient undergoing conversion from planned pulmonary lobectomy or anatomical segmentectomy to atypical resection, bilobectomy or pneumonectomy;\n* Drainage via two chest drains;\n* Absence of autonomous drainage system;\n* Patient not extubated at the end of the procedure;\n* Early reoperation, before drain removal, due to complications.",{"count":324,"type":22},"Air leak from lung after major pulmonary resections is alveolar-pleural microfistulas resulting from damage to the visceral pleura during lung surgery. Despite advances in stapling techniques and repair methods to ensure pulmonary tightness after excision, air leak is the most common cause of prolonged hospital stay after lung surgery, accounting for 20 to 30% of post-surgical adverse events.\n\nAlthough painless, they remain a significant source of morbidity. 10 to 20% of patients may have a prolonged air leak requiring intervention. Prolonged air leak is defined as an air leakage that persists for 5 days or more. Prolonged air leak is independently associated with increased hospitalization costs of 18% to 27% according to the series reported in the literature, but also with increased costs after hospital discharge, up to 90 days postoperatively.\n\nTraditionally, the detection of air leak at the end of surgery is done by testing the lung for submersion in saline solution. With the development of major pulmonary resection techniques by conventional or robotic thoracoscopy (with closed chest), this method has become ineffective because it requires re-ventilating the lung in a closed rib cage, which cancels the visibility of the camera. However, the frequency of these adverse events and the morbidity associated with them now induces the placement of post-operative drains, which are very painful, unlike the leak itself, which makes the pain even more complex to bear for patients.\n\nGiven the rapid transition to a minimally invasive surgical approach, having a method to detect and quantify intraoperative air leak on a closed chest is necessary in order to accelerate patients' postoperative recovery, reducing their postoperative pain while controlling the incidence of complications.\n\nA recent study has shown that the risk of postoperative air leak is possible based exclusively on intraoperative ventilator measurements, but the data are still too scarce to rely on them extensively.",[391,392],"Air Leak From Lung","Lung Surgery",[394],"intraoperative ventilation","2026-03-27",{"date":397,"type":31},"2026-03-30",{"date":399,"type":31},"2026-01-14",{"date":313,"type":22},{"name":37,"class":38},{"id":403,"slug":404,"hasResults":12,"nctId":405,"briefTitle":406,"officialTitle":407,"acronym":408,"eligibilityCriteria":409,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":164,"enrollmentInfo":410,"targetDuration":4,"studyType":50,"phases":412,"briefSummary":413,"conditions":414,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":416,"startDateStruct":417,"completionDateStruct":418,"leadSponsor":420,"locationsCount":39},"100609125","therapeutic-benefits-of-a-motor-imaging-protocol-following-anterior-cruciate-ligament-reconstruction-surgery-100609125","NCT07210489","Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery","Therapeutic Benefits of a Motor Imaging Protocol After Anterior Cruciate Ligament Reconstruction Surgery: Study of Lower Limb Symmetry During Various Functional Tests","IMAGERIEMOTR","Inclusion Criteria:\n\n* Patients aged 18 to 45;\n* Individuals who have undergone anterior cruciate ligament reconstruction for the first time on the operated leg;\n* All types of surgery (harvesting of the new gracilis or patellar tendon) within 3 months prior to inclusion;\n* Patients able to understand and read French;\n* Affiliation with a social insurance plan;\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Recurrence or rupture of the contralateral anterior cruciate ligament;\n* Osteotomy;\n* Cognitive disorders observed by the investigator;\n* Vestibular disorders known to the patient or observed by the investigator;\n* Post-surgical complications (infection, early graft rupture);\n* Patient participating in another interventional clinical trial, or in a period of exclusion from another interventional study;\n* Patient under guardianship or conservatorship;\n* Pregnant or breastfeeding women.",{"count":411,"type":22},70,[77],"The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months post-surgery versus patients who did not receive the motor imagery program.",[415],"Anterior Cruciate Ligament Tear",{"date":397,"type":31},{"date":62,"type":22},{"date":419,"type":22},"2027-03",{"name":37,"class":38},{"id":422,"slug":423,"hasResults":12,"nctId":424,"briefTitle":425,"officialTitle":426,"acronym":427,"eligibilityCriteria":428,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":429,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":431,"conditions":432,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":438,"leadSponsor":439,"locationsCount":39},"100557000","study-of-post-operative-complications-after-laparoscopic-outpatient-nephrectomy-100557000","NCT06532422","Study of Post-operative Complications After Laparoscopic Outpatient Nephrectomy","Study of Post-operative Complications After Laparoscopic Outpatient Nephrectomy in Patients With Localised Kidney Cancer","NEPHRAMBU","Inclusion Criteria:\n\n* Patients over 18 ;\n* Localised kidney cancer ;\n* Validation of curative treatment at a multidisciplinary consultation meeting;\n* Partial or total laparoscopic nephrectomy scheduled on an outpatient basis;\n* Membership of a social security scheme or receiving State Medical Aid;\n* Patient able to understand the information relating to the study, to read the information leaflet and who has given his\u002Fher oral non-objection.\n\nExclusion Criteria:\n\n* Emergency intervention ;\n* Patient not eligible for outpatient treatment;\n* Long-term curative anti-coagulant treatment ;\n* Resident more than 100km from the clinic;\n* Home alone on the first night;\n* Patient of protected age (under guardianship or curatorship, or deprived of liberty).",{"count":430,"type":22},50,"The purpose of this study is to compare to assess the incidence of post-operative complications related to nephrectomy, which occur up to 1 month after the operation.",[433],"Kidney Cancer",{"date":435,"type":31},"2026-04-01",{"date":437,"type":31},"2024-12-13",{"date":153,"type":22},{"name":37,"class":38},{"id":441,"slug":442,"hasResults":12,"nctId":443,"briefTitle":444,"officialTitle":445,"acronym":446,"eligibilityCriteria":447,"healthyVolunteers":12,"sex":448,"minAge":19,"maxAge":4,"enrollmentInfo":449,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":451,"conditions":452,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":454,"startDateStruct":455,"completionDateStruct":457,"leadSponsor":459,"locationsCount":39},"100514229","outpatient-laparoscopic-radical-prostatectomy-100514229","NCT05975775","Outpatient Laparoscopic Radical Prostatectomy","Study of Postoperative Complications After Laparoscopic Outpatient Radical Prostatectomy in Patients With Localized Prostate Cancer","LORP","Inclusion Criteria:\n\n* Male, age ≥ 18 years;\n* Localized prostate cancer;\n* Validation in a multidisciplinary consultation meeting of curative treatment;\n* Scheduled laparoscopic radical prostatectomy;\n* Patient able to understand the information related to the study, to read the information leaflet and to signify his\u002Fher non-opposition or opposition to participating in the study;\n* Membership of a social security scheme;\n* Patient having been informed and having given oral non-opposition.\n\nExclusion Criteria:\n\n* Surgical emergency;\n* Patient not eligible for ambulatory care;\n* Long-term curative anti-coagulant treatment;\n* Resident more than 100km from the clinic;\n* Home alone the first night;\n* Patient under guardianship, curatorship or deprivation of liberty.","MALE",{"count":450,"type":22},64,"The purpose of the study is to evaluate the incidence of surgery-related complications between Day 0 and Day 30.",[453],"Prostate Cancer",{"date":397,"type":31},{"date":456,"type":31},"2023-10-20",{"date":458,"type":22},"2026-10",{"name":37,"class":38},{"id":461,"slug":462,"hasResults":12,"nctId":463,"briefTitle":464,"officialTitle":465,"acronym":466,"eligibilityCriteria":467,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":468,"targetDuration":4,"studyType":50,"phases":470,"briefSummary":471,"conditions":472,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":474,"startDateStruct":475,"completionDateStruct":477,"leadSponsor":479,"locationsCount":39},"100512251","clinical-improvement-obtained-by-endoscopic-ilio-psoas-tenotomy-lesser-trochanter-versus-acetabular-notch-100512251","NCT05950022","Clinical Improvement Obtained by Endoscopic Ilio-Psoas Tenotomy (Lesser Trochanter Versus Acetabular Notch)","Study Evaluating the Clinical Improvement Obtained by Endoscopic Tenotomy of the Ilio-Psoas, at the Level of the Lesser Trochanter Versus at the Level of the Acetabular Notch, on Psoas Cup Impingements After Total Hip Prosthesis","ETIPIC","Inclusion Criteria:\n\n* Age ≥ 18 years old;\n* Definite diagnosis of iliopsoas tendinopathy due to conflict between the tendon and the prosthetic cup;\n* Failure of first-line conservative treatment;\n* Planned endoscopic tenotomy;\n* Affiliation to the social security scheme;\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Revision total hip prosthesis, multiple operations prior to tenotomy;\n* Other surgical or medical interventions planned during the study;\n* Participation in another clinical trial, or during a period of exclusion from another clinical trial;\n* Pregnant or likely to be pregnant (of childbearing age, without effective contraception) or breastfeeding;\n* Patient deprived of liberty or under guardianship or curatorship or unable to give consent.",{"count":469,"type":22},108,[77],"The purpose of the study is to assess Oxford Hip Score at baseline, at 2 months and at over 12 months.",[473],"Tendinopathy",{"date":435,"type":31},{"date":476,"type":31},"2023-12-19",{"date":478,"type":22},"2028-12",{"name":37,"class":38},{"id":481,"slug":482,"hasResults":12,"nctId":483,"briefTitle":484,"officialTitle":484,"acronym":485,"eligibilityCriteria":486,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":487,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":489,"conditions":490,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":492,"startDateStruct":493,"completionDateStruct":495,"leadSponsor":497,"locationsCount":39},"100506190","longitudinal-prospective-french-multicenter-cohort-study-on-pancreatic-radiofrequency-100506190","NCT05871164","Longitudinal, Prospective, French, Multicenter Cohort Study on Pancreatic Radiofrequency","RAFPAN2","Inclusion Criteria:\n\n* Age ≥ 18 years old;\n* Patient to be treated for a pancreatic tumor by ultrasound-guided RF with a fine needle;\n* Indication of pancreatic radiofrequency validated in a Multidisciplinary Consultation Meeting;\n* Patient able to understand the information related to the study;\n* Patient accepting study follow-up visits;\n* Patient having been informed and agreeing to participate in the study.\n\nExclusion Criteria:\n\n* Patient with a contraindication to radiofrequency treatment;\n* Pregnant or breastfeeding women",{"count":488,"type":22},200,"The purpose of the study is to evaluate the oncological efficacy of pancreatic radiofrequency by the objective response rate (complete and partial responses according to RECIST 1.1.), 5 years after the end of treatment.",[491],"Pancreatic Tumor",{"date":435,"type":31},{"date":494,"type":31},"2023-06-12",{"date":496,"type":22},"2030-05",{"name":37,"class":38},{"id":499,"slug":500,"hasResults":12,"nctId":501,"briefTitle":502,"officialTitle":503,"acronym":504,"eligibilityCriteria":505,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":506,"targetDuration":4,"studyType":50,"phases":508,"briefSummary":509,"conditions":510,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":512,"lastUpdatePostDateStruct":513,"startDateStruct":515,"completionDateStruct":517,"leadSponsor":518,"locationsCount":39},"100600162","study-comparing-two-anesthetics-for-arthroscopic-rotator-cuff-repair-100600162","NCT07093905","Study Comparing Two Anesthetics for Arthroscopic Rotator Cuff Repair","Prospective, Randomized Study Comparing General Anesthesia Combined With Locoregional Anesthesia to Locoregional Anesthesia Alone for Arthroscopic Rotator Cuff Repair.","ALRAGA","Inclusion Criteria:\n\n* Age ≥ 18 years;\n* Patients with surgically repairable complete or partial rotator cuff tears;\n* American Society of Anesthesiologists Class I to III;\n* Patient able to understand study information;\n* Patient willing to accept study evaluations and follow-up visits;\n* Affiliation with a social insurance plan;\n* Patient having been informed and having agreed to participate in the study by signing an informed consent form.\n\nExclusion Criteria:\n\n* Contraindication to general or locoregional anesthesia;\n* Chronic opioid use;\n* Patient unable to understand study information (linguistic, psychological, cognitive, etc.);\n* Patient unable to answer a self-questionnaire;\n* Patient participating in or being excluded from another interventional research study;\n* Pregnant or breast-feeding women;\n* Protected patient (under legal protection, guardianship or deprived of liberty by judicial or administrative decision).",{"count":507,"type":22},34,[77],"The purpose of this study is to to compare the post-anesthetic recovery time to awake consciousness and hemodynamic and ventilatory capacities for discharge from the Post-Interventional Monitoring Room in patients admitted for shoulder rotator cuff arthroscopy (using local anesthesia versus general anesthesia + local anesthesia).",[511],"Rotator Cuff Syndrome","2026-03-13",{"date":514,"type":31},"2026-03-16",{"date":516,"type":31},"2026-03-12",{"date":313,"type":22},{"name":37,"class":38},{"id":520,"slug":521,"hasResults":12,"nctId":522,"briefTitle":523,"officialTitle":523,"acronym":524,"eligibilityCriteria":525,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":526,"targetDuration":4,"studyType":50,"phases":528,"briefSummary":529,"conditions":530,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":532,"lastUpdatePostDateStruct":533,"startDateStruct":535,"completionDateStruct":537,"leadSponsor":539,"locationsCount":39},"100496642","haemostatic-gel-prophylaxis-for-post-duodenal-endoscopic-resection-bleeding-100496642","NCT05746884","Haemostatic Gel Prophylaxis for Post Duodenal Endoscopic Resection Bleeding","PURASTAT","Inclusion Criteria:\n\nAmpullary lesions\n\n* Single ampullary lesion ≥ 10mm\n* Resection via hot ampullectomy, injection\u002FEndoscopic mucosal resection of adjacent lateral spreading component Duodenal Lesions\n* ≤ 2 lesions\n* Lesion ≥15mm\n* Resection via hot Endoscopic mucosal resection\n* Morphology: 0-Is, 0-IIa\u002Fb\u002Fc or combination, submucosal lesions\n\nExclusion Criteria:\n\n* Inability to provide informed consent (including people with cognitive impairment);\n* Pregnant or breastfeeding women;\n* Allergy to PuraStat®;\n* \"Cold\" mucosal endoscopic resection;\n* Patient under guardianship or curatorship, or under a regime of deprivation of liberty;\n* Participating patient, or in a period of exclusion from another clinical trial;\n* Patient not benefiting from a social security scheme.",{"count":527,"type":22},234,[77],"The purpose of this study is to test whether prophylactic application of haemostatic gel will reduce the rate of clinically significant bleeding requiring intervention (such as blood transfusion, admission to hospital, other blood products) following endoscopic resection of advanced duodenal neoplasia compared to standard therapy.",[531],"Duodenal Bleeding","2026-02-24",{"date":534,"type":31},"2026-02-27",{"date":536,"type":31},"2023-08-21",{"date":538,"type":22},"2028-09-30",{"name":37,"class":38},""]