[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Gansu Provincial Maternal and Child Health Care Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":61},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100634773","transradial-vs-transfemoral-group-randomized-efficacy-and-safety-trial-for-cerebral-angiography-100634773",false,"NCT07544043","Transradial vs Transfemoral Group-Randomized Efficacy and Safety Trial for Cerebral Angiography","Transradial vs Transfemoral Group-Randomized Efficacy and Safety Trial for Cerebral Angiography：A Prospective, Multicenter, Cluster-Randomized Controlled, Open-Label, Blinded Endpoint Evaluation Study（TARGET-CA）","TARGET-CA","Inclusion Criteria:\n\n1. Age \\> 18 years;\n2. Patients requiring full cerebrovascular angiography;\n3. Objective evidence indicates the patient is suitable for transfemoral or transradial cerebrovascular angiography, with upper limb vascular ultrasound 4.showing a radial artery internal diameter ≥ 1.5 mm;\n\n5.Modified Rankin Scale (mRS) score ≤ 2 points; 6.Signed informed consent form.\n\nExclusion Criteria:\n\n1. Positive right Allen's test\u002FBarbeau test; femoral artery occlusion (for the TFA group);\n2. Local infection or trauma at the puncture site;\n3. Coagulation abnormalities: INR \\> 1.5 or platelet count \\\u003C 50 × 10⁹\u002FL;\n4. Presence of access vessel disease or anatomical variation deemed potentially hazardous to the subject, such as aortic arch interruption, subclavian artery occlusion, or aortic dissection;\n5. Pregnancy;\n6. Planned or recent (within the past 2 weeks) major surgery or severe trauma;\n7. Expected survival less than 5 years;\n8. Severe cardiac, hepatic, renal, or other organ dysfunction;\n9. Contraindication to contrast agents used in cerebrovascular angiography;\n10. Inability to comply with follow-up.","ALL","18 Years",{"count":20,"type":21},2473,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will compare the efficacy and safety of the transradial approach versus the transfemoral approach for performing full cerebral angiography. Participants will undergo cerebral angiography via one of the two approaches and will be followed up during and after the procedure. The primary endpoint of this study is to evaluate the success rate of completing full cerebral angiography (including superselective catheterization of bilateral common carotid arteries, subclavian arteries near the vertebral artery origin, and the aortic arch) via the transradial approach versus the transfemoral approach. During the study, the medical team will also document procedural details, incidence of complications, patient comfort, and related costs to comprehensively evaluate the clinical performance differences between the two approaches.",[27],"Cerebrovascular Disease","NOT_YET_RECRUITING","2026-04-19",{"date":31,"type":32},"2026-04-22","ACTUAL",{"date":34,"type":21},"2026-05-01",{"date":36,"type":21},"2027-05-01",{"name":38,"class":39},"Gansu Provincial Maternal and Child Health Care Hospital","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":47,"maxAge":18,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":4,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":4},"100635251","prospective-registry-of-acute-ischemic-stroke-in-children-under-18-years-old-in-china-100635251","NCT07550257","Prospective Registry of Acute Ischemic Stroke in Children Under 18 Years Old in China","Prospective Registry of Acute Ischemic Stroke in Children Under 18 Years Old in China (KIDS-AIS-REGISTRY)","Inclusion Criteria:\n\n* Age \\>28 days and \\\u003C18 years;\n* Presence of stroke-related symptoms (hemiparesis, facial palsy, aphasia, altered level of consciousness, seizure, headache) or atypical symptoms (sudden lethargy or irritability, crying, feeding difficulties, incontinence, sensory loss, ataxia, vertigo, nausea and\u002For vomiting, neck pain, fever);\n* First-ever stroke and onset within ≤7 days prior to admission;\n* Acute ischemic stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI);\n* Legal guardian provides signed informed consent;\n* For children aged ≥8 years to \\\u003C18 years who are conscious and without comprehension impairment, assent obtained from the child;\n\nExclusion Criteria:\n\n* Lack of imaging examination or stroke diagnosed without imaging\n* History of hypoxic-ischemic encephalopathy\n* Ischemic stroke caused by cerebral venous system\n* Concurrent presence of indistinguishable ischemic and hemorrhagic stroke","28 Days",{"count":49,"type":21},1000,"OBSERVATIONAL","This observational study aims to investigate the real-world effectiveness and safety of different treatment strategies for acute ischemic stroke (AIS) in Chinese children under 18 years of age.\n\nIts primary research question is: In real-world clinical practice, does endovascular therapy (e.g., stent retriever thrombectomy, aspiration thrombectomy) improve 90-day functional outcomes in pediatric AIS patients with acute anterior or posterior circulation large vessel occlusion? Children under 18 years of age receiving routine AIS diagnosis and treatment at approximately 25-35 study centers across China will undergo neurological function assessments, imaging examinations, and evaluations of growth, development, and psychosocial status at baseline, 24 hours post-procedure, 7 days post-procedure or at hospital discharge, and at 90 days and 6 months post-onset. Adverse events will also be documented.",[53],"Acute Ischemic Stroke (AIS), Pediatric Stroke",{"date":55,"type":32},"2026-04-24",{"date":57,"type":21},"2026-06-01",{"date":59,"type":21},"2029-12-31",{"name":38,"class":39},""]