[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Gary Goldfield\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":65},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100625955","the-rewire-behaviour-study-100625955",false,"NCT07429357","The REWIRE Behaviour Study","Research on Education With Individualized REwarding Behaviour (REWIRE): A Comparison of Two Youth Mental Health Programs","REWIRE","Inclusion Criteria:\n\n* Own a smartphone.\n* Use social media for \\>3 hours\u002Fday.\n* Are aged 12-17 years.\n* Are experiencing feelings of anxiety or depression.\n* Have a caregiver who is able and willing to participate in the study alongside them.\n* Have the ability to communicate in English.\n* Must sign and date the informed consent form, or provide assent and have a Substitute Decision Maker provide informed consent\n\nExclusion Criteria:\n\n* Own a smartphone.\n* Use their smartphone for \\>1 hour\u002Fday.\n* Are accompanying a youth participant enrolled in the study.\n* Have the ability to communicate in English.\n* Are willing to sign informed consent forms.","ALL","12 Years","17 Years",{"count":21,"type":22},220,"ESTIMATED","INTERVENTIONAL",[25],"NA","This two-phase, double-blind, balanced, parallel-group randomized controlled trial involves youth aged 12 to 17 years who experience symptoms of anxiety or depression and use social media for more than three hours per day.\n\nIn Phase 1, a small pilot group will participate in the REWIRE program to assess its feasibility, usability, and engagement before launching Phase 2. Results of the pilot will inform whether any modifications to the intervention are required and identify ways to increase adherence and reduce barriers.\n\nIn Phase 2, approximately 100 youth and their caregivers will be randomly assigned to one of two groups to evaluate the REWIRE program on anxiety and depression symptoms. One group will participate in the REWIRE program, which aims to reduce social media use to about half of usual levels while encouraging participation in positive offline activities such as spending time with friends, hobbies, physical activity, or time outdoors. The comparison group will receive psychoeducation about social media and health, but will not be asked to change their social media use. Both youth and caregivers will attend weekly group sessions over 12-weeks. Participants will also track their physical activity, complete questionnaires about mental health, daily activities, and social media use, and will provide daily smartphone usage screenshots. Youth will additionally take part in brain imaging scans and neurocognitive assessments before and after the program to explore how changes in social media use may be related to brain function. At the end of Phase 2, 20 participants will be randomly selected for interviews to explore their experiences with the intervention.\n\nAdditional secondary outcomes in Phase 2 include social phobia, social comparison, Fear of Missing Out (FOMO), loneliness, body esteem, disordered eating, social media disorder symptoms, cyberbullying, reinforcing efficacy of social media, impulsivity, suicidal ideations, well-being, executive functioning and cognition, while further assessing the feasibility.",[28,29],"Anxiety Depression","Social Media","NOT_YET_RECRUITING","2026-02-20",{"date":33,"type":34},"2026-02-24","ACTUAL",{"date":36,"type":22},"2026-03",{"date":38,"type":22},"2029-12",{"name":40,"class":41},"Gary Goldfield","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":42},"100603001","the-mb-eat-smart-teen-study-100603001","NCT07130838","The MB-EAT Smart Teen Study","Effects of Application-Based Mindfulness and Eating Awareness Training on Disordered Eating in Youth With Obesity: The MB-EAT Study","MB-EAT","Inclusion Criteria:\n\n* Have access to a mobile\u002Ftablet device with internet access\n* Are aged 12-17.5 years\n* Are waitlisted or have recently been waitlised for treatment at CHAL at CHEO\n* Are willing and capable to sign consent\u002Fassent forms\n* Have the ability to complete the study in English\n\nExclusion Criteria:\n\n* Are currently enrolled in psychotherapy or a weight management program\n* Have previously been diagnosed with Bulimia Nervosa, purging subtype\n* Have previously been diagnosed with a condition that may impair cognition and neurodevelopment, particularly Fetal Alcohol Syndrome, Down Syndrome, Prader-Willi Syndrome, and Fragile X Syndrome\n* Have previously been diagnosed with ASD\n* Have had a concussion or brain injury in the past 6-months.",{"count":52,"type":22},170,[25],"This two-phase, double-blind, balanced, parallel-group randomized controlled trial evaluates the feasibility, usability, engagement, and clinical impact of an app-based adaptation of the Mindfulness-Based Eating Awareness Training (MB-EAT) program for adolescents living with obesity.\n\nMB-EAT, has been shown to reduce binge eating episodes, improve food-related self-control, and decrease depressive symptoms in adults with obesity. The app based program promotes mindful awareness and self-regulation in response to hunger and satiety cues, without caloric restriction.\n\nYouth aged 12-17.5 years who are waitlisted or have recently been waitlisted for treatment at the Centre for Healthy Active Living (CHAL) at the Children's Hospital of Eastern Ontario (CHEO) will be enrolled in a 4-week app-based MB-EAT program (Phase 1, n=10) to evaluate feasibility, usability, and engagement.\n\nPhase 2 is a 12-week randomized controlled trial with 160 participants who will be randomized to the experimental arm (app-based MB-EAT program; 60-90 minutes\u002Fweek) or an active comparator arm (app-based psychoeducation) to evaluate whether the MB-EAT program improves disinhibited eating. At the end of the intervention, 20 participants will be randomly selected for interviews to explore their experiences with the app.\n\nAdditional secondary outcomes in Phase 2 include depressive symptoms, anxiety symptoms, emotion regulation, dispositional mindfulness, food craving, mindful eating, body image, health-related quality of life, impact of weight on quality of life, internalized weight bias, food impulsivity, and food reinforcement.",[56],"Obesity &Amp; Overweight","2025-08-18",{"date":59,"type":34},"2025-08-19",{"date":61,"type":22},"2025-10-01",{"date":63,"type":22},"2028-04-01",{"name":40,"class":41},""]