[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Gaziantep City Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":291},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,53,80,108,139,174,199,231,264],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":25,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":4},"100644664","foreign-national-burn-patients-in-a-border-region-burn-center-100644664",false,"NCT07673796","Foreign-National Burn Patients in a Border-Region Burn Center","Clinical Characteristics and In-Hospital Outcomes of Foreign-National Burn Patients in a Border-Region Burn Center: A Retrospective Cohort Study","Inclusion Criteria: Patients hospitalized and treated with a diagnosis of burn injury at the Burn Center of Gaziantep City Hospital between October 2023 and June 2026.\n\nPatients with a confirmed diagnosis of burn injury in patient files, discharge summaries, or hospital information management system records.\n\nPatients whose nationality status can be classified as Turkish citizen or foreign-national according to hospital records.\n\nPatients with available basic demographic, clinical, and in-hospital outcome data.\n\nPatients of all age groups and both sexes.\n\nExclusion Criteria: Patients treated outside the predefined study period. Patients without a confirmed diagnosis of burn injury. Patients evaluated only in the outpatient setting without hospitalization. Patients with missing nationality data. Patients with insufficient demographic or clinical outcome data for analysis. Duplicate records related to the same burn event; only the first hospitalization will be included.\n\nPatients evaluated only for consultation without hospitalization at the Burn Center of Gaziantep City Hospital.\n\n\\-","ALL",{"count":18,"type":19},1400,"ESTIMATED","OBSERVATIONAL","This retrospective cohort study will evaluate burn patients hospitalized and treated at the Burn Center of Gaziantep City Hospital between October 2023 and June 2026. The study aims to compare demographic characteristics, burn severity, clinical course, and in-hospital outcomes between Turkish citizens and foreign-national burn patients.\n\nData will be obtained retrospectively from patient files, discharge summaries, intensive care records, operative notes, and the hospital information management system. Variables will include age, sex, nationality status, burn etiology, total body surface area burned, inhalation injury, sepsis, intensive care unit admission, mechanical ventilation requirement, surgical treatment requirement, number of operations, length of hospital stay, discharge status, transfer to another center, and in-hospital mortality.\n\nNo additional intervention, diagnostic test, treatment, or follow-up procedure will be performed as part of this study. All analyses will be conducted using anonymized or coded retrospective clinical data.",[23,24],"Burn Injury","Burns",[26,27,28,29,30,31,32,33,34,35,36,37,38,39,40],"Burn injury","Burn center","Foreign-national patients","Refugees","Border region","Retrospective cohort","Total body surface area","Inhalation injury","Intensive care","Mechanical ventilation","Sepsis","In-hospital mortality","ABSI score","Revised Baux score","Ryan-based modified clinical score","NOT_YET_RECRUITING","2026-06-23",{"date":44,"type":45},"2026-06-29","ACTUAL",{"date":47,"type":19},"2026-07",{"date":49,"type":19},"2026-09",{"name":51,"class":52},"Gaziantep City Hospital","OTHER",{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},"100641174","esp-vs-subcostal-tap-block-for-analgesia-after-laparoscopic-cholecystectomy-100641174","NCT07661693","ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy","Comparison Of Ultrasound-guided Erector Spinae Plane Block And Subcostal Transversus Abdominis Plane Block For Postoperative Analgesia In Laparoscopic Cholecystectomy: A Prospective Randomized Double-blind Multicenter Trial","ESP TAP","Inclusion Criteria:\n\nAdults aged 18 years and older\n\nScheduled for elective laparoscopic cholecystectomy under general anesthesia\n\nAmerican Society of Anesthesiologists (ASA) physical status I-III\n\nAbility to understand the study protocol and provide written informed consent -\n\nExclusion Criteria:Refusal to participate\n\nKnown allergy or contraindication to local anesthetic agents\n\nCoagulopathy or anticoagulant therapy contraindicating regional anesthesia\n\nInfection at the planned injection site\n\nBody mass index (BMI) \\> 35 kg\u002Fm²\n\nChronic opioid use or opioid dependence\n\nChronic pain syndromes requiring regular analgesic treatment\n\nSevere hepatic, renal, or cardiac dysfunction\n\nPregnancy or breastfeeding\n\nInability to communicate or assess pain using the Numerical Rating Scale (NRS)\n\n\\-",{"count":62,"type":19},100,"INTERVENTIONAL",[65],"NA","This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic cholecystectomy. The primary outcome is 24-hour postoperative opioid consumption. Secondary outcomes include postoperative pain scores, time to first analgesic request, shoulder pain, postoperative nausea and vomiting, and block-related complications.",[68],"Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy",[70],"ESP Block, TAP Block, Regional Anesthesia, Ultrasound, Laparoscopic Cholecystectomy, Postoperative Analgesia, Opioid Use","2026-06-16",{"date":73,"type":45},"2026-06-22",{"date":75,"type":19},"2027-06-15",{"date":77,"type":19},"2027-09-15",{"name":51,"class":52},1,{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":91,"conditions":92,"keywords":97,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":107,"locationsCount":4},"100619603","evaluation-of-anterior-neck-ultrasound-in-predicting-difficult-airway-in-obese-patients-100619603","NCT07346768","Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients","Ultrasound Assessment of Anterior Neck Soft Tissue Thickness to Predict Difficult Airway Risk in Obese Patients Undergoing for Surgery Under General Anesthesia: an Observational Study","Inclusion Criteria:\n\n* Age 18-70 years\n* ASA physical status I-III\n\n  \\* BMI \\>25 kg\u002Fm²\n* Scheduled for elective surgery under general anesthesia\n\nExclusion Criteria:\n\n* Emergency surgery\n* Pregnancy\n* Maxillofacial anomalies or neck masses\n* Rapid sequence induction\n* Previous history of difficult intubation\n* BMI \\>60 kg\u002Fm²","18 Years","70 Years",{"count":90,"type":19},52,"Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues. Accurate preoperative prediction of difficult airway remains challenging using conventional clinical airway assessment tests alone.\n\nThis prospective observational study aims to evaluate the role of ultrasound assessment of anterior neck soft tissue thickness in predicting difficult airway risk in overweight and obese adult patients undergoing elective surgery under general anesthesia. Ultrasound-based anterior neck measurements will be compared with standard clinical airway assessment parameters to determine their diagnostic accuracy for difficult laryngoscopy and intubation.\n\nThe results of this study may contribute to improved preoperative airway risk stratification and safer airway management in obese patients.",[93,94,95,96],"Ultrasonography","Airway Management","Intubation, Intratracheal","Obesity and Overweight",[98,99,100,101],"Obesity","difficult airway","anterior neck ultrasound","ultrasonography","2026-06-12",{"date":71,"type":45},{"date":105,"type":19},"2026-06-20",{"date":105,"type":19},{"name":51,"class":52},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":63,"phases":118,"briefSummary":119,"conditions":120,"keywords":124,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":79},"100643364","evaluation-of-the-effectiveness-of-capacitive-and-resistive-energy-transfer-therapy-for-lateral-epicondylitis-100643364","NCT07634224","Evaluation of the Effectiveness of Capacitive and Resistive Energy Transfer Therapy for Lateral Epicondylitis","Effectiveness of Capacitive and Resistive Energy Transfer Therapy in Patients With Lateral Epicondylitis: A Sham-Controlled, Double-Blind Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients with lateral epicondylitis who have experienced elbow pain for at least 6 weeks and have at least two positive provocative tests (Cozen's, Mill's, or Maudsley's test).\n* Age between 18 and 65 years.\n* Unilateral pain and tenderness over the lateral epicondyle lasting longer than 6 weeks.\n* Clinically diagnosed lateral epicondylitis.\n* No cognitive impairment.\n* Willingness to participate and provide informed consent.\n\nExclusion Criteria:\n\n* History of interventional injection to the affected elbow within the previous 3 months.\n* Receipt of physical therapy for the affected elbow within the previous 3 months.\n* Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) within the previous 2 weeks.\n* History of fracture or surgery involving the affected elbow.\n* Presence of a chronic inflammatory disease.\n* History of malignancy.\n* Active infection.\n* Pregnancy.\n* Presence of a cardiac pacemaker or other electronic implant.\n* Coagulation disorders.\n* Cervical radiculopathy, entrapment neuropathy, or peripheral nerve injury.\n* Body mass index (BMI) ≥ 35 kg\u002Fm².","65 Years",{"count":117,"type":19},62,[65],"This prospective, randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy of Capacitive and Resistive Energy Transfer (TECAR) therapy in patients with lateral epicondylitis. Participants will be randomly assigned to either a TECAR plus exercise group or a sham TECAR plus exercise group.\n\nBoth groups will receive a standardized home exercise program including elbow and wrist range-of-motion, stretching, eccentric strengthening, and handgrip strengthening exercises. The TECAR group will additionally receive active TECAR therapy, while the control group will receive sham TECAR treatment using the same device and treatment protocol without therapeutic energy delivery.\n\nOutcome assessments will be performed by a blinded evaluator at baseline, immediately after treatment, and at 1- and 2-month follow-up visits. The study aims to determine whether TECAR therapy provides additional benefits in pain relief, functional improvement, and clinical outcomes when combined with exercise therapy in patients with lateral epicondylitis.",[121,122,123],"Lateral Epicondylitis","Capacitive and Resistive Electric Transfer Therapy","Exercise",[125,126,127,128,129],"Lateral epicondylitis","Capacitive and resistive energy transfer therapy (TECAR)","Exercise therapy","Rehabilitation","Randomized controlled trial","RECRUITING","2026-06-09",{"date":133,"type":45},"2026-06-11",{"date":135,"type":45},"2026-05-11",{"date":137,"type":19},"2027-05-11",{"name":51,"class":52},{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":146,"sex":16,"minAge":87,"maxAge":147,"enrollmentInfo":148,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":150,"conditions":151,"keywords":155,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":4},"100639198","combined-rsbi-tof-and-bis-for-prediction-of-extubation-success-100639198","NCT07577453","Combined RSBI, TOF, and BIS for Prediction of Extubation Success","Predictive Value of Combined RSBI, TOF, and BIS Monitoring for Extubation Success After General Anesthesia","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* ASA physical status I-III\n* Patients scheduled for elective surgery under general anesthesia\n* Patients undergoing endotracheal intubation during general anesthesia\n* Patients receiving neuromuscular blocking agents during anesthesia\n* Patients planned for extubation in the operating room\n* Availability of pre-extubation RSBI, TOF ratio, and BIS measurements\n* Written informed consent obtained from the patient\n\nExclusion Criteria:\n\n* Emergency surgery\n* Age \\\u003C18 years or \\>80 years\n* ASA physical status IV or higher\n* Known or anticipated difficult airway\n* Anticipated difficult extubation\n* Preoperative mechanical ventilation\n* Planned postoperative mechanical ventilation or transfer to the intensive care unit while intubated\n* Known neuromuscular disease\n* Severe chronic respiratory failure\n* Severe chronic obstructive pulmonary disease associated with respiratory failure\n* Significant neurological disease affecting respiratory drive or level of consciousness\n* Conditions or medications that may interfere with reliable neuromuscular monitoring\n* Inability to obtain reliable RSBI, TOF ratio, or BIS measurements\n* Refusal to participate\n* Incomplete perioperative or post-extubation outcome data",true,"80 Years",{"count":149,"type":19},150,"This prospective observational study aims to evaluate the predictive value of the combined use of the rapid shallow breathing index, train-of-four ratio, and bispectral index for extubation success after general anesthesia. Adult patients undergoing elective surgery under general anesthesia and planned for extubation in the operating room will be included.\n\nBefore extubation, RSBI, TOF ratio, BIS value, respiratory parameters, and relevant perioperative data will be recorded. The decision to extubate will be made by the attending anesthesiologist according to routine clinical practice and will not be altered by the study protocol. Patients will be followed for 30 minutes after extubation to assess extubation success or the development of complications such as desaturation, laryngospasm, need for airway intervention, mask ventilation, or reintubation.\n\nThe primary aim is to determine whether the combined RSBI, TOF, and BIS model predicts extubation success more accurately than each parameter alone.",[152,153,154],"Extubation Success","Extubation Failure","Postoperative Respiratory Complications",[156,157,158,159,160,161,162,163,164,165],"Extubation","Extubation Succcess","Extubation failure","General anesthesia","Rapid shallow breathing index","TOF ratio","Bispectral index","Neuromuscular monitoring","Postoperative respiratory complications","Prediction model","2026-05-09",{"date":168,"type":45},"2026-05-13",{"date":170,"type":19},"2026-06-15",{"date":172,"type":19},"2026-08-15",{"name":51,"class":52},{"id":175,"slug":176,"hasResults":11,"nctId":177,"briefTitle":178,"officialTitle":179,"acronym":4,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":147,"enrollmentInfo":181,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":182,"conditions":183,"keywords":185,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":196,"leadSponsor":198,"locationsCount":4},"100633868","agreement-between-artificial-intelligence-and-anesthesiologists-in-ultrasound-guided-axillary-brachial-plexus-block-100633868","NCT07532278","Agreement Between Artificial Intelligence and Anesthesiologists in Ultrasound-Guided Axillary Brachial Plexus Block","Evaluation of Agreement Between Artificial Intelligence and Experienced Anesthesiologists in Target Point Identification for Ultrasound-Guided Axillary Brachial Plexus Block: A Prospective Observational Study","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Patients scheduled for upper extremity surgery under ultrasound-guided axillary brachial plexus block as part of routine clinical practice\n* Ability to obtain adequate real-time ultrasound imaging of the axillary region prior to block performance\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Inability to clearly visualize the axillary artery and at least one peripheral nerve (median, ulnar, radial, or musculocutaneous) on ultrasound imaging\n* Presence of significant ultrasound artifacts impairing image interpretation\n* History of previous surgery in the axillary region causing anatomical distortion\n* Anatomical deformities or significant anatomical variations in the axillary region\n* Inadequate ultrasound image quality due to severe obesity or other technical limitations\n* Failure to obtain real-time ultrasound imaging prior to block performance\n* Withdrawal of informed consent",{"count":62,"type":19},"This prospective observational study aims to evaluate the agreement between artificial intelligence (AI)-assisted target point identification and experienced anesthesiologists during ultrasound-guided axillary brachial plexus block.\n\nUltrasound guidance is widely used in regional anesthesia to improve block success and safety. However, accurate identification of anatomical structures and optimal injection points remains operator-dependent. Artificial intelligence-based systems have the potential to assist clinicians by identifying anatomical landmarks in real time.\n\nIn this study, AI-generated target points will be compared with those determined by experienced anesthesiologists. The level of agreement between the two methods will be analyzed. Secondary outcomes will include block performance parameters and image quality.\n\nThe findings of this study may contribute to understanding the clinical utility of AI in ultrasound-guided regional anesthesia.",[184],"Ultrasound-Guided Nerve Block and Artificial Intelligence",[186,187,188,189,190,191],"Ultrasound-Guided Regional Anesthesia","Axillary Brachial Plexus Block","Artificial Intelligence","Ultrasound Imaging","Anatomical Structure Recognition","Agreement Analysis","2026-04-09",{"date":194,"type":45},"2026-04-15",{"date":194,"type":19},{"date":197,"type":19},"2026-07-15",{"name":51,"class":52},{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":205,"eligibilityCriteria":206,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":115,"enrollmentInfo":207,"targetDuration":4,"studyType":63,"phases":209,"briefSummary":210,"conditions":211,"keywords":215,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":79},"100631305","comparison-of-paravertebral-block-and-deep-parasternal-intercostal-plane-block-in-cardiac-surgery-100631305","NCT07498946","Comparison of Paravertebral Block and Deep Parasternal Intercostal Plane Block in Cardiac Surgery","Comparison of Ultrasound-Guided Thoracic Paravertebral Block and Bilateral Deep Parasternal Intercostal Plane Block in Adult Patients Undergoing Elective Cardiac Surgery Via Median Sternotomy: A Prospective Randomized Controlled Trial","SPARE-CABG","Inclusion Criteria:\n\nAge 18 to 65 years Scheduled for elective cardiac surgery via median sternotomy American Society of Anesthesiologists physical status II or III Planned to undergo surgery under general anesthesia Able to comply with postoperative pain assessment using the Visual Analog Scale Able to provide written informed consent\n\nExclusion Criteria:\n\nEmergency cardiac surgery Cardiac surgery performed through an approach other than median sternotomy Redo sternotomy Local infection or skin disruption at the planned block site Known allergy or hypersensitivity to amide local anesthetics Clinically significant coagulopathy or antiplatelet\u002Fanticoagulant treatment preventing safe regional block according to institutional protocol Clinically unstable condition or high risk for pleural complications that would make the block unsafe Chronic opioid use or chronic pain syndrome Advanced musculoskeletal disease or deformity that may interfere with pain assessment Neurological or psychiatric disorder causing inability to comply with postoperative pain assessment Cognitive impairment preventing reliable pain assessment Clinically significant peripheral neuropathy or other neurosensory condition affecting pain perception Pregnancy or breastfeeding Severe pulmonary disease, including advanced chronic obstructive pulmonary disease or severe restrictive lung disease Anticipated inability to comply with the study protocol",{"count":208,"type":19},80,[65],"Median sternotomy is commonly used in cardiac surgery and is often associated with significant postoperative pain. Poor pain control after sternotomy may increase opioid use, delay mobilization, prolong extubation time, and contribute to respiratory complications and longer hospital stay. Regional analgesia techniques may help improve pain management and reduce opioid requirements after surgery.\n\nThis study is a prospective, randomized, single-center clinical trial that will compare two ultrasound-guided regional analgesia techniques in adult patients undergoing elective cardiac surgery through median sternotomy: thoracic paravertebral block and bilateral deep parasternal intercostal plane block. A total of 80 patients will be randomly assigned in a 1:1 ratio to receive one of these two blocks in addition to standard general anesthesia and routine multimodal analgesia.\n\nThe main objective of the study is to compare the effects of these two techniques on total opioid consumption during the first 24 hours after surgery. Secondary outcomes include postoperative pain scores, need for additional analgesics, analgesia-related side effects such as nausea, vomiting, or respiratory depression, and extubation time. Pain will be assessed using a visual analog scale at predefined time points during the first 24 postoperative hours.\n\nThe study hypothesis is that there will be a clinically meaningful difference in postoperative analgesic effectiveness between thoracic paravertebral block and bilateral deep parasternal intercostal plane block in patients undergoing cardiac surgery via median sternotomy. The results of this study may help guide the selection of the most appropriate regional analgesia technique for pain control after sternotomy.",[212,213,214],"Postoperative Pain","Cardiac Surgery","Postoperative Pain After Cardiac Surgery Via Median Sternotomy",[212,213,216,217,218,219,220,221,222],"Median Sternotomy","Thoracic Paravertebral Block","Deep Parasternal Intercostal Plane Block","Regional Analgesia","Ultrasound-Guided Nerve Block","Opioid Consumption","Visual Analog Scale","2026-03-23",{"date":225,"type":45},"2026-03-27",{"date":227,"type":19},"2026-04-18",{"date":229,"type":19},"2027-04-18",{"name":51,"class":52},{"id":232,"slug":233,"hasResults":11,"nctId":234,"briefTitle":235,"officialTitle":236,"acronym":4,"eligibilityCriteria":237,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":115,"enrollmentInfo":238,"targetDuration":4,"studyType":63,"phases":239,"briefSummary":240,"conditions":241,"keywords":244,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":79},"100617183","preoperative-deep-parasternal-intercostal-plane-block-and-intraoperative-opioid-use-in-cardiac-surgery-100617183","NCT07315308","Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery","Preoperative Ultrasound-Guided Deep Parasternal Intercostal Plane Block Reduces Intraoperative Opioid Consumption in Adults Undergoing Cardiac Surgery Via Median Sternotomy","Inclusion Criteria:\n\nAdults aged 18 to 65 years Scheduled to undergo elective cardiac surgery via median sternotomy Planned general anesthesia Able to provide written informed consent\n\nExclusion Criteria:\n\nKnown allergy or contraindication to local anesthetics Coagulation disorders or ongoing anticoagulant therapy that contraindicates regional anesthesia Infection at or near the planned injection site Pre-existing chronic pain conditions requiring long-term opioid use Severe cognitive impairment or inability to communicate pain intensity Emergency surgery Refusal or inability to provide informed consent",{"count":208,"type":19},[65],"Median sternotomy is commonly used in cardiac surgery and is associated with significant intraoperative and postoperative pain, often requiring substantial opioid administration. High opioid use during cardiac surgery may contribute to adverse effects such as respiratory depression, delayed extubation, postoperative nausea and vomiting, and prolonged intensive care unit stay. Therefore, effective opioid-sparing strategies are an important component of modern perioperative care.\n\nThe deep parasternal intercostal plane (DPIP) block is a regional anesthesia technique that targets the anterior cutaneous branches of the intercostal nerves, which are responsible for transmitting pain from the sternum and adjacent tissues. When performed under ultrasound guidance, this block allows precise local anesthetic deposition while minimizing the risk of pleural or vascular injury.\n\nThe purpose of this randomized controlled study is to evaluate whether a preoperative ultrasound-guided DPIP block reduces intraoperative opioid consumption in adult patients undergoing elective cardiac surgery via median sternotomy. Patients will be randomly assigned to receive either a bilateral DPIP block in addition to standard general anesthesia or standard general anesthesia alone.\n\nThe primary outcome of the study is total intraoperative opioid consumption. Secondary outcomes include time to extubation, postoperative opioid consumption within the first 24 hours, postoperative pain scores, and the incidence of opioid-related adverse effects. The results of this study may help define the role of the DPIP block as part of a multimodal, opioid-sparing analgesic strategy in cardiac surgery.",[212,242,221,243],"Sternotomy","Intraoperative Pain Control",[245,246,247,248,249,250,251,252,253,254,255],"Deep parasternal intercostal plane block","Parasternal block","Ultrasound-guided regional anesthesia","Sternotomy analgesia","Cardiac surgery pain management","Opioid-sparing analgesia","Multimodal analgesia","Anterior chest wall block","Regional anesthesia in cardiac surgery","Intraoperative Pain","Intraoperative Opioid Consumption","2026-03-02",{"date":258,"type":45},"2026-03-04",{"date":260,"type":45},"2026-02-12",{"date":262,"type":19},"2027-01-01",{"name":51,"class":52},{"id":265,"slug":266,"hasResults":11,"nctId":267,"briefTitle":268,"officialTitle":269,"acronym":270,"eligibilityCriteria":271,"healthyVolunteers":11,"sex":272,"minAge":87,"maxAge":273,"enrollmentInfo":274,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":276,"conditions":277,"keywords":279,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":284,"lastUpdatePostDateStruct":285,"startDateStruct":286,"completionDateStruct":288,"leadSponsor":290,"locationsCount":4},"100624223","spinal-versus-general-anesthesia-in-pregnancies-with-placenta-accreta-spectrum-a-retrospective-comparative-study-100624223","NCT07406841","Spinal Versus General Anesthesia in Pregnancies With Placenta Accreta Spectrum: A Retrospective Comparative Study","Comparison of Spinal and General Anesthesia on Maternal and Neonatal Outcomes in Pregnancies With Placenta Accreta Spectrum: A Retrospective Study","SAGA-PAS","Inclusion Criteria:\n\n* Pregnant patients diagnosed with placenta accreta spectrum (PAS), Undergoing elective cesarean delivery, Receiving either spinal anesthesia or general anesthesia during cesarean section, Singleton pregnancy, Availability of complete medical and anesthesia records related to surgery and perioperative management\n\nExclusion Criteria:\n\nPatients without a diagnosis of PAS, Emergency (non-elective) cesarean deliveries, Use of anesthesia techniques other than spinal or general anesthesia, Multiple pregnancy (twins or more) ,Incomplete or missing medical\u002Fanesthesia records, Missing key perioperative or neonatal outcome data","FEMALE","45 Years",{"count":275,"type":19},50,"Placenta accreta spectrum (PAS) is a serious pregnancy complication in which the placenta grows abnormally into the uterine wall. This condition is associated with a high risk of severe bleeding, need for blood transfusion, hysterectomy, and maternal complications during cesarean delivery.\n\nThis study aims to compare spinal anesthesia and general anesthesia in pregnant women diagnosed with placenta accreta spectrum who underwent cesarean delivery. The researchers reviewed existing medical records to evaluate differences in maternal and neonatal outcomes between the two anesthesia approaches.\n\nThe primary outcomes include changes in hemoglobin levels before and after surgery, the need for uterotonic medications during and after the operation, and newborn Apgar scores. Because this is a retrospective observational study, no new treatments were given, and all data were collected from routine clinical care records.\n\nThe findings are expected to help guide anesthetic decision-making in PAS cases, improve maternal and neonatal safety, and contribute to the international scientific literature on this topic.",[278],"Placenta Accreta Spectrum",[280,281,282,283],"Placenta accreta spectrum","PAS","spinal anesthesia","general anesthesia","2026-02-11",{"date":260,"type":45},{"date":287,"type":19},"2026-02-01",{"date":289,"type":19},"2026-03-30",{"name":51,"class":52},""]