[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Gaziosmanpasa Research and Education Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":667},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,26,0,25,[9,47,83,113,136,158,187,217,244,268,299,321,348,378,404,428,451,476,499,526,551,574,603,628,648],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100628266","the-effect-of-peloidotherapy-in-young-adults-undergoing-physical-therapy-scoliosis-specific-exercises-psse-100628266",false,"NCT07459400","The Effect of Peloidotherapy in Young Adults Undergoing Physical Therapy Scoliosis Specific Exercises (PSSE)","The Effect of Peloidotherapy on Pain and Quality of Life in Young Adult Individuals With Scoliosis Undergoing Physiotherapy Scoliosis-Specific Exercises (PSSE)","Inclusion Criteria:\n\n* Aged 20-40 years\n* Diagnosed with idiopathic scoliosis by a specialist physician\n* Cobb angle between 15-40 degrees\n* Able to perform PSSE exercises throughout the study period\n* VAS ≥3 at the start of the study\n* Has had pain complaints for at least 3 months\n* Individuals who have agreed in writing to participate in the study\n\nExclusion Criteria:\n\n* Individuals who have undergone scoliosis surgery\n* Individuals with neuromuscular, congenital, or secondary scoliosis\n* Individuals with rheumatological, inflammatory, or serious chronic diseases (such as cardiopulmonary insufficiency or kidney disease)\n* Pregnant and breastfeeding women\n* Conditions in which peloidotherapy is contraindicated (active skin infection, open wound, serious dermatological disease, history of allergic reaction, severe cardiopulmonary, kidney or liver failure, bleeding disorder or anticoagulant use, pregnancy\u002Fbreastfeeding, and systemic infection)\n* Individuals with serious psychiatric disorders that may interfere with treatment compliance or affect consent\n* Individuals receiving additional physical therapy during the study period","ALL","20 Years","40 Years",{"count":21,"type":22},54,"ESTIMATED","4 Months","OBSERVATIONAL","Scoliosis is a musculoskeletal disorder defined by a three-dimensional spinal deformity that can result in substantial clinical and functional limitations, particularly during adolescence and young adulthood. Affected individuals commonly experience postural asymmetry, muscular imbalance, pain, and diminished quality of life. In conservative management, Physiotherapeutic Scoliosis-Specific Exercises (PSSE) have gained recognition as a fundamental intervention. The primary objectives of PSSE include optimizing spinal alignment, facilitating rotational breathing, and restoring muscular symmetry to improve functional capacity. Evidence from systematic reviews suggests that PSSE, especially the Schroth method, are superior to general exercise programs in improving both radiographic parameters and health-related quality of life.Meta-analytic findings further support the effectiveness of PSSE in reducing curve magnitude and enhancing quality of life outcomes. Among the various PSSE approaches, the Schroth method is one of the most extensively investigated and widely applied in clinical settings. This method incorporates three-dimensional postural correction, targeted breathing techniques, and the development of postural awareness. Randomized controlled trials have demonstrated that Schroth exercises significantly improve SRS-22 quality of life scores and positively influence pain, body image, and overall well-being.Despite these established benefits, pain and muscle tension occurring during exercise sessions may negatively influence adherence to rehabilitation programs. In young adults, pain is a critical factor limiting treatment compliance and restricting engagement in daily activities. Accordingly, adjunctive interventions implemented prior to exercise may enhance exercise tolerance and optimize therapeutic outcomes.Peloidotherapy, which involves the therapeutic application of natural medicinal mud, is commonly used in musculoskeletal rehabilitation due to its analgesic, muscle-relaxant, and circulation-enhancing effects. By alleviating pain and reducing muscular tension, peloidotherapy may facilitate greater participation in exercise programs and support improved clinical outcomes.This study aims to investigate the effects of adjunctive peloidotherapy administered before Schroth-based PSSE in young adults with scoliosis, focusing on pain, exercise adherence, and quality of life, with particular emphasis on SRS-22 measures..",[27,28,29],"Spine Deformity","Adult Scoliosis","Peloidotherapy",[29,28,31,32,33],"Physiotherapy Scoliosis-Specific Exercises (PSSE)","Pain","Quality of Life","RECRUITING","2026-06-08",{"date":37,"type":38},"2026-06-10","ACTUAL",{"date":40,"type":38},"2026-03-23",{"date":42,"type":22},"2026-10-23",{"name":44,"class":45},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":12,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},"100639336","effects-of-aquatic-exercise-in-older-adults-with-sarcopeniaa-randomized-trial-100639336","NCT07575958","Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial","Effects of Aquatic Exercise Program on Muscle Strength, Muscle Mass, Physical Performance and Quality of Life in Older Adults With Sarcopenia: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age ≥65 years\n2. Diagnosis of \"definite sarcopenia\" according to the ISarcoPRM diagnostic algorithm\n3. Not receiving nutritional supplementation and not requiring nutritional support according to the Mini Nutritional Assessment (MNA)\n4. Sufficient cognitive ability to understand and follow instructions, including study-related questions and the home exercise program\n5. Voluntary participation in the study\n6. Ability to ambulate independently (assistive devices such as a cane are allowed; however, fully dependent individuals will be excluded)\n\nExclusion Criteria:\n\n1. Inability to complete assessment tests and questionnaires\n2. Presence of severe systemic disease that may contraindicate exercise\n3. Severe visual or hearing impairment\n4. Presence of a cardiac pacemaker\n5. Severe cardiopulmonary disease\n6. Uncontrolled hypertension\n7. Uncontrolled diabetes mellitus\n8. Receiving nutritional supplementation\n9. Severe anemia\n10. Conditions contraindicating hydrotherapy, including aquaphobia (fear of water), behavioral disorders, dyspnea at rest, urinary or fecal incontinence, known chlorine allergy, open wounds, acute systemic illness, epilepsy, tracheostomy, indwelling drainage devices, and immunodeficiency","65 Years",{"count":56,"type":22},44,"INTERVENTIONAL",[59],"NA","Sarcopenia is a geriatric syndrome characterized by age-related loss of skeletal muscle mass, strength, and physical performance, leading to increased risk of falls, functional decline, and reduced quality of life. Exercise interventions, particularly resistance training, are effective in managing sarcopenia; however, land-based exercises may be challenging for older adults due to balance impairments, joint problems, and fear of falling.\n\nPool-based exercise programs may offer a safe and feasible alternative, as water buoyancy reduces joint loading while providing resistance to support muscle strengthening. Despite these potential benefits, evidence regarding the effects of aquatic exercise in individuals with sarcopenia remains limited, especially in Türkiye.\n\nThis study aims to evaluate the effects of a 6-week supervised pool-based exercise program on muscle strength, muscle morphology, physical performance, mood, and quality of life in individuals aged 65 years and older with sarcopenia. Sarcopenia will be identified using the Sonographic Thigh Adjustment Ratio (STAR), based on ultrasound measurements of anterior thigh muscle thickness. In addition, appendicular skeletal muscle mass will be assessed using bioelectrical impedance analysis (ASM\u002Fheight²).\n\nOutcome measures will include ultrasound-based muscle thickness, STAR, muscle strength, functional performance tests, depressive symptoms, and health-related quality of life. Assessments will be performed at baseline, immediately after the intervention, and at 1-month follow-up.",[62,63],"Sarcopenia","Sarcopenia in Elderly",[65,66,67,68,69,70,71,72,73],"sarcopenia","aquatic exercise","hydrotherapy","aquatic therapy","sarcopenia ultrasound","Geriatric","Elderly","water-based exercise","Sonographic Thigh Adjustment Ratio(STAR)","2026-05-07",{"date":76,"type":38},"2026-05-12",{"date":78,"type":38},"2026-04-01",{"date":80,"type":22},"2026-07",{"name":44,"class":45},2,{"id":84,"slug":85,"hasResults":12,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":57,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":4},"100635936","ai-chi-based-rehabilitation-for-peripheral-unilateral-vestibular-dysfunction-100635936","NCT07559162","Ai Chi-Based Rehabilitation for Peripheral Unilateral Vestibular Dysfunction","Contribution of an Ai Chi-Based Rehabilitation Program in Patients With Peripheral Unilateral Vestibular Dysfunction: A Randomized Prospective Single-Blind Study","AICHI-VR","Inclusion Criteria:\n\n* Age between 18 and 70 years\n* Diagnosis of unilateral peripheral vestibular hypofunction\n* Presence of dizziness symptoms for at least 3 months\n* Ability to participate in Ai Chi and aquatic exercise program\n* Berg Balance Scale score ≥21\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Inability to complete assessment tests and questionnaires\n* Severe systemic disease that may interfere with exercise participation\n* Central vestibular disorders\n* Berg Balance Scale score ≤20\n* Severe visual or hearing impairment\n* Initiation or change of psychiatric medication within the last 3 weeks\n* Severe cardiopulmonary disease\n* Contraindications to hydrotherapy, including water phobia, behavioral disorders, dyspnea at rest, incontinence, known chlorine allergy, open wounds, acute systemic illness, epilepsy, tracheostomy, permanent drainage devices, immunodeficiency, or known neurological disorders","FEMALE","18 Years","70 Years",{"count":95,"type":22},38,[59],"This study aims to evaluate the effects of an Ai Chi-based rehabilitation program on balance, dizziness severity, and quality of life in patients with unilateral peripheral vestibular hypofunction. Participants will be randomly assigned to either a control group receiving standard home-based vestibular rehabilitation exercises or an intervention group receiving additional Ai Chi sessions. The intervention will be conducted over a 4-week period with a total of 10 sessions under the supervision of a certified therapist.",[99,100,101,102,103,104],"Unilateral Peripheral Vestibular Hypofunction","Vestibular Disorders","Dizziness","Vertigo Benign Positional","Dizziness and Vertigo","Vestibular Function Disorder","NOT_YET_RECRUITING","2026-05-04",{"date":74,"type":38},{"date":109,"type":22},"2026-04-27",{"date":111,"type":22},"2026-07-27",{"name":44,"class":45},{"id":114,"slug":115,"hasResults":12,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":57,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":130,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":46},"100636321","ultrasound-guided-dextrose-prolotherapy-for-coccydynia-a-prospective-study-100636321","NCT07564167","Ultrasound-Guided Dextrose Prolotherapy for Coccydynia: A Prospective Study","Evaluation of the Effectiveness of Dextrose Prolotherapy on Pain Severity and Functional Status in Patients With Coccydynia: A Prospective Study","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* Pain persisting for ≥3 months and refractory to conservative treatment\n* Coccydynia of mechanical or idiopathic origin\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>75 years\n* Pregnancy\n* Allergy to the proliferant solution\n* Active infection\n* Use of anticoagulant medications\n* Presence of malignancy\n* Local abscess\n* Hemorrhagic diathesis\n* Certain types of septic arthritis\n* Parafunctional habits","75 Years",{"count":122,"type":22},30,[59],"Coccydynia is a musculoskeletal condition characterized by pain in the coccygeal region, particularly exacerbated by sitting, and is associated with impaired quality of life and functional limitation. Although various conservative and interventional treatment options are available, there remains a need for effective and safe alternative therapies, especially in treatment-resistant cases.\n\nProlotherapy is a regenerative treatment modality that aims to reduce pain and improve function by stimulating tissue repair, particularly in ligamentous structures. While there is increasing evidence supporting its effectiveness in mechanical musculoskeletal pain conditions, the literature regarding its use in coccydynia is limited.\n\nThe aim of this study is to evaluate the effect of dextrose prolotherapy on pain severity and functional status in patients diagnosed with coccydynia. This study is designed as a prospective, single-arm, open-label interventional study. Patients will receive 15% dextrose prolotherapy according to a standardized protocol. Pain severity will be assessed using the Visual Analog Scale (VAS), and functional status will be evaluated using the Dallas Pain Questionnaire before treatment and at 1 month after completion of the treatment.\n\nThis study aims to provide more comprehensive data on the effectiveness and safety of prolotherapy in coccydynia and to contribute to the currently limited evidence in the literature.",[126],"Coccydynia",[126,128,129],"Dextrose Prolotherapy","Ultrasound-Guided Injection",{"date":106,"type":38},{"date":132,"type":38},"2026-01-15",{"date":134,"type":22},"2026-06-15",{"name":44,"class":45},{"id":137,"slug":138,"hasResults":12,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":57,"phases":145,"briefSummary":146,"conditions":147,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":46},"100628267","oral-vs-intravenous-hydration-to-prevent-contrast-associated-acute-kidney-injury-in-the-ed-100628267","NCT07459413","Oral vs. Intravenous Hydration to Prevent Contrast-Associated Acute Kidney Injury in the ED","Evaluation of the Effectiveness of Oral Hydration Compared to Intravenous Hydration in Preventing Contrast-Associated Acute Kidney Injury in the Emergency Department : A Randomized Controlled Non-Inferiority Trial","Inclusion Criteria:\n\n* Patients aged 18 years and older.\n* Patients with an estimated Glomerular Filtration Rate (eGFR) between 15-59 mL\u002Fmin\u002F1.73 m².\n* Patients undergoing contrast-enhanced computed tomography (CT) in the emergency department.\n* Patients who have provided written informed consent.\n\nExclusion Criteria:\n\n* Pregnant women.\n* Patients with end-stage renal disease (ESRD) receiving dialysis or those with an eGFR \\\u003C15 mL\u002Fmin\u002F1.73 m².\n* Patients presenting with decompensated heart failure.\n* Patients with a known allergy to iodinated contrast media.\n* Patients with contrast media exposure within the last 72 hours.\n* Patients for whom oral intake is contraindicated or who cannot tolerate oral intake",{"count":144,"type":22},198,[59],"This study is planned to be conducted by emergency physicians between November 7, 2025, and December 7, 2026.\n\nInclusion and Exclusion Criteria The study will include adult patients aged 18 years and older who are considered at risk for Contrast-Associated Acute Kidney Injury (CA-AKI), with an estimated Glomerular Filtration Rate (eGFR) between 15-59 ml\u002Fmin\u002F1.73 m², a clinical indication for contrast-enhanced CT, and who have provided signed informed consent.\n\nExclusion criteria are as follows:\n\nPregnant women.\n\nPatients with a known contrast media allergy.\n\nContrast media exposure within the last 72 hours.\n\nEnd-stage renal disease (ESRD) with eGFR \\\u003C15 ml\u002Fmin\u002F1.73 m² or those receiving dialysis.\n\nPatients with clinical decompensated heart failure.\n\nPatients for whom oral intake is contraindicated or not tolerated.\n\nRandomization and Interventions Prior to randomization, the oral intake capacity of eligible patients will be verified. Participants will be randomized into two groups-IV hydration and oral hydration-at a 1:1 ratio using stratified block randomization based on age and gender.\n\nIV Hydration Group: Isotonic 0.9% NaCl solution will be administered. The regimen consists of 3 ml\u002Fkg for 1 hour pre-procedure, followed by 2 ml\u002Fkg\u002Fhour for 4 hours post-procedure. Patients with an ejection fraction (EF) \\\u003C40% will receive half-doses (1.5 ml\u002Fkg pre-procedure; 1 ml\u002Fkg\u002Fhour for 4 hours post-procedure).\n\nOral Hydration Group: Drinking water will be administered under nursing supervision. The regimen consists of 500 ml 1 hour pre-procedure and 125 ml\u002Fhour for 4 hours post-procedure. Patients with an EF \\\u003C40% will receive half-doses (250 ml pre-procedure; 62.5 ml\u002Fhour post-procedure).\n\nFollow-up and Outcome Measures Baseline renal function tests will be obtained from all patients prior to the protocol. Patients will be re-evaluated for CA-AKI via blood samples taken 48-72 hours after contrast administration.\n\nFurthermore, eGFR changes will be calculated using the Modification of Diet in Renal Disease (MDRD) formula. Mehran Risk Scores will also be determined for each patient. Long-term outcomes, including progression to ESRD (requirement for dialysis) and mortality within 1 month, as well as creatinine levels between days 30-45, will be assessed.",[148,149],"Contrast-Associated Acute Kidney Injury","Contrast-induced Nephropathy","2026-03-05",{"date":152,"type":38},"2026-03-09",{"date":154,"type":38},"2025-11-07",{"date":156,"type":22},"2026-12-07",{"name":44,"class":45},{"id":159,"slug":160,"hasResults":12,"nctId":161,"briefTitle":162,"officialTitle":162,"acronym":4,"eligibilityCriteria":163,"healthyVolunteers":12,"sex":17,"minAge":164,"maxAge":92,"enrollmentInfo":165,"targetDuration":4,"studyType":57,"phases":167,"briefSummary":168,"conditions":169,"keywords":174,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":46},"100613036","the-effect-of-three-dimensional-exercises--schroth-method--on-trunk-muscle-endurance-sleep-quality-and-quality-of-life-in-adolescents-with-hyperkyphosis-100613036","NCT07261358","The Effect of Three-Dimensional Exercises ( Schroth Method ) on Trunk Muscle Endurance, Sleep Quality, and Quality of Life in Adolescents With Hyperkyphosis","Inclusion Criteria:\n\n* Adolescents between 12 and 18 years of age\n* Presence of thoracic kyphosis with a T3-T12 Cobb angle ≥45° measured on a lateral thoracic radiograph\n* Sufficient physical and cognitive ability to actively participate in the exercise protocol for at least 3 months\n* Adequate communication and cognitive capacity to understand the educational materials provided\n* Ability and willingness to regularly complete the exercise log throughout the study period\n\nExclusion Criteria:\n\n* Scoliosis with a Cobb angle \\>10° in the coronal plane\n* Presence of structural spinal deformities such as vertebral fracture, spondylolisthesis\n* History of previous spinal surgery\n* Neuromuscular disorders that may affect the spine (e.g., cerebral palsy, muscular dystrophy)\n* Structural or functional pathologies involving the spine, pelvic complex, or shoulder girdle\n* Balance disorders such as vestibular dysfunction, vertigo, or other conditions affecting postural control\n* Inability to comply with the exercise protocol due to intellectual disability, severe behavioral disorders, or significant communication impairments\n* Participation in professional-level sports activities that may influence exercise capacity or musculoskeletal function\n* Presence of serious cardiopulmonary diseases (e.g., congenital heart disease, pulmonary hypertension)","12 Years",{"count":166,"type":22},60,[59],"Adolescence is a critical period for spinal growth, and progression of thoracic hyperkyphosis may lead to pain, weak trunk muscles, sleep disturbances, and reduced quality of life. This study aims to investigate the effects of three-dimensional exercise program based on the Schroth Method on trunk muscle endurance, thoracic kyphosis angle, pain, sleep quality and quality of life in adolescents aged 12-18 years with hyperkyphosis.",[27,170,171,172,173],"Kyphosis","Adolescent","Sleep Quality","Trunk Muscle Endurance",[175,176,177,178],"postural kyphosis","sleep quality","trunk muscle endurance","adolescent spine deformity","2026-02-08",{"date":181,"type":38},"2026-02-11",{"date":183,"type":38},"2025-10-06",{"date":185,"type":22},"2026-05-01",{"name":44,"class":45},{"id":188,"slug":189,"hasResults":12,"nctId":190,"briefTitle":191,"officialTitle":192,"acronym":4,"eligibilityCriteria":193,"healthyVolunteers":12,"sex":17,"minAge":194,"maxAge":195,"enrollmentInfo":196,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":198,"conditions":199,"keywords":203,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":46},"100623623","evaluation-of-the-effects-of-adenoidectomy-and-adenotonsillectomy-on-voice-in-children-100623623","NCT07399041","Evaluation of the Effects of Adenoidectomy and Adenotonsillectomy on Voice in Children","A Prospective Single-Center Study Evaluating the Effects of Adenoidectomy and Adenotonsillectomy on Voice and Speech Functions in Children","Inclusion Criteria:\n\n* Aged 4-13 years\n* Scheduled for primary adenoidectomy or adenotonsillectomy\n\nExclusion Criteria:\n\n* Does not meet inclusion criteria\n* Refuses to participate in the study\n* Diagnosis of vocal cord disorders\n* History of vocal cord surgery\n* History of cleft palate or cleft lip\n* Hearing loss requiring a hearing aid\n* Chronic diseases that may impair wound healing, including: hypertension, diabetes mellitus, immunodeficiency, autoimmune diseases, rheumatologic diseases, connective tissue disorders, renal failure, liver failure, chronic heart disease\n* Known bleeding diathesis\n* Use of anticoagulant or antiplatelet drugs\n* Upper respiratory tract infection within the last 2 weeks\n* Patients undergoing revision adenoidectomy","4 Years","13 Years",{"count":197,"type":22},36,"This prospective study aims to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in children. Changes in voice quality and resonance may occur after the removal of adenoid and tonsillar tissues, particularly in pediatric patients with enlarged adenoids or tonsils.\n\nObjective voice assessments, including acoustic, aerodynamic, and nasalance measurements, as well as subjective voice-related quality of life questionnaires, will be performed before surgery and at the first and third months after surgery. The results of this study are expected to help clinicians better inform families about possible voice changes following adenoidectomy and adenotonsillectomy procedures.",[200,201,202],"Adenoid Hypertrophy","Tonsillar Hypertrophy","Voice Disorders in Children",[204,205,206,207,208],"Adenoidectomy","Adenotonsillectomy","Pediatric Voice","Nasalance","praat","2026-02-02",{"date":211,"type":38},"2026-02-10",{"date":213,"type":22},"2026-02",{"date":215,"type":22},"2026-08",{"name":44,"class":45},{"id":218,"slug":219,"hasResults":12,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":224,"sex":17,"minAge":92,"maxAge":225,"enrollmentInfo":226,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":228,"conditions":229,"keywords":232,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":243,"locationsCount":46},"100615541","ultrasonographic-evaluation-of-talar-cartilage-thickness-in-patients-with-spinal-cord-injury-100615541","NCT07293949","Ultrasonographic Evaluation of Talar Cartilage Thickness in Patients With Spinal Cord Injury","Ultrasonographic Evaluation of Talar Cartilage Thickness in Patients With Spinal Cord Injury: A Cross-Sectional Case-Control Study","Inclusion Criteria:\n\n* Aged between 18 to 60 years,\n* Cervical, thoracal or lumber level of spinal cord injury\n* AIS (American Spinal Injury Association Impairment Scale) Level A, B, C, or D\n* Assisted ambulation of any kind\n* Literacy\n* Giving oral and written consent to participate in the study\n\nExclusion Criteria:\n\n* Patients with sacral level injury\n* AIS E\n* MAS 4 level of spasticity\n* History of any lower extremity operation\n* History of fracture\n* Botulinum toxin injection in the last 6 months\n* Existing diagnosis of any rheumatologic or endocrine diseases",true,"60 Years",{"count":227,"type":22},76,"Spinal cord injury patients often present with musculoskeletal comorbidities, including osteoarthritis. Early detection of cartilage damage is important for preventing osteoarthritis progression. This study aims to compare the talar cartilage thicknesses of spinal cord injury patients with healthy subjects. The secondary aim is to investigate a correlation between the talar cartilage thickness and disease-related parameters. The patient group is to be assessed for talar cartilage thickness (via ultrasound), functional status, spasticity, and ambulation levels.",[230,231],"Spinal Cord Injuries (SCI)","Osteoarthritis (OA)",[233,234,235,236],"spinal cord injury","osteoarthritis","musculoskeletal ultrasound","talar cartilage","2026-01-30",{"date":209,"type":38},{"date":240,"type":38},"2025-12-20",{"date":242,"type":22},"2026-03-01",{"name":44,"class":45},{"id":245,"slug":246,"hasResults":12,"nctId":247,"briefTitle":248,"officialTitle":249,"acronym":4,"eligibilityCriteria":250,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":120,"enrollmentInfo":251,"targetDuration":252,"studyType":24,"phases":4,"briefSummary":253,"conditions":254,"keywords":256,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":260,"lastUpdatePostDateStruct":261,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":46},"100621577","proximal-versus-distal-superior-cluneal-nerve-block-in-entrapment-neuropathy-100621577","NCT07372430","Proximal Versus Distal Superior Cluneal Nerve Block in Entrapment Neuropathy","Proximal Versus Distal Superior Cluneal Nerve Block in Superior Cluneal Nerve Entrapment: A Prospective, Randomized, Single-Blind Trial","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* Chronic low back and\u002For gluteal pain lasting longer than 3 months\n* Localized point tenderness and\u002For paresthesia on palpation over the unilateral posterior iliac crest\n* Clinical suspicion of superior cluneal nerve entrapment based on physical examination\n* Failure to respond to conservative treatment\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Active local or systemic infection\n* Cognitive impairment or psychiatric disorders interfering with study participation\n* History of malignancy or cancer-related pain\n* Uncontrolled diabetes mellitus or severe comorbid conditions adversely affecting general health\n* Pregnancy\n* Known allergy to the medications used in the injection\n* Prominent radicular pain associated with neurological deficit\n* History of interventional procedures applied to the lumbar region within the last 6 months\n* Initiation of another lumbar interventional or medical treatment during the follow-up period\n* Suspected bilateral superior cluneal nerve entrapment\n* Sphincter dysfunction related to neurological disease\n* Bleeding diathesis or coagulation disorders",{"count":21,"type":22},"3 Months","Superior cluneal nerve (SCN) entrapment is an underdiagnosed cause of chronic low back and gluteal pain. Although diagnostic nerve block is considered the gold standard for confirming SCN entrapment, there is no consensus regarding the optimal injection approach. This prospective observational study aims to compare the clinical effectiveness of proximal and distal ultrasound-guided SCN block techniques in patients diagnosed with SCN entrapment. Pain intensity and functional outcomes will be evaluated over the follow-up period to assess differences between the two approaches.",[255],"Cluneal Syndrome",[257,258,259],"Neuralgia","Peripheral Nerve Entrapment","low back pain","2026-01-19",{"date":262,"type":38},"2026-01-28",{"date":264,"type":38},"2025-12-12",{"date":266,"type":22},"2026-07-01",{"name":44,"class":45},{"id":269,"slug":270,"hasResults":12,"nctId":271,"briefTitle":272,"officialTitle":273,"acronym":274,"eligibilityCriteria":275,"healthyVolunteers":224,"sex":91,"minAge":92,"maxAge":276,"enrollmentInfo":277,"targetDuration":279,"studyType":24,"phases":4,"briefSummary":280,"conditions":281,"keywords":286,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":46},"100613870","thyroid-stimulating-hormone-levels-in-pregnancy-and-their-association-with-depression-anxiety-and-sexual-function-100613870","NCT07272213","Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function","Evaluation of the Effects of Thyroid-Stimulating Hormone (TSH) Levels in Pregnancy on Depression, Anxiety, and Sexual Function","TSH-MIND","Inclusion Criteria:\n\nPregnant women aged 18-45 years\n\nSingleton pregnancy\n\nGestational age ≥ 6 weeks\n\nLiteracy and ability to provide informed consent\n\nAvailability of a TSH result obtained within the past 4 weeks\n\nCognitive ability sufficient to complete the psychometric questionnaires (Beck Depression Inventory, Beck Anxiety Inventory, ASEX, and YKK-13 Quality of Life Scale)\n\nExclusion Criteria:\n\nMultiple pregnancy\n\nPreviously diagnosed psychiatric disorder or active use of antidepressant\u002F anxiolytic medication\n\nCurrent treatment for thyroid disease\n\nHistory of thyroid surgery\n\nMajor systemic illness or significant obstetric complications\n\nAge under 18 years or inability to provide informed consent\n\nInability to complete the questionnaires adequately (missing or invalid data)\n\nRationale:\n\nMultiple pregnancies are excluded because they differ significantly from singleton pregnancies in terms of hormonal profile, obstetric risks, and psychological stress levels. This exclusion aims to ensure a homogeneous study population.","45 Years",{"count":278,"type":22},180,"1 Month","This prospective, single-center, observational cross-sectional study aims to evaluate the relationship between thyroid-stimulating hormone (TSH) levels and psychological as well as sexual health outcomes during pregnancy. Pregnant individuals will undergo psychometric assessment using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), the Arizona Sexual Experience Scale (ASEX), and the YKK-13 Quality of Life Scale. The study will investigate whether maternal TSH levels are associated with depression, anxiety, sexual function, and overall quality of life scores.\n\nEligible participants will be pregnant women aged 18-45 years with a singleton pregnancy of at least 6 weeks, who are literate and have provided informed consent. Individuals with a prior psychiatric history, multiple gestation, or existing systemic or endocrine diseases will be excluded. The primary endpoint of the study is to determine the association between TSH levels and psychometric scale scores during pregnancy.",[282,283,284,285],"Thyroid Disorders Complicating Pregnancy","Maternal Depression in Pregnancy, Unspecified Trimester","Anxiety Disorder, Unspecified","Sexual Dysfunction, Unspecified",[287,288,289,290],"Thyroid disorders complicating pregnancy","Maternal depression in pregnancy, unspecified trimester","Anxiety disorder, unspecified","Sexual dysfunction, unspecified","2025-11-26",{"date":293,"type":38},"2025-12-09",{"date":295,"type":38},"2025-11-01",{"date":297,"type":22},"2025-12-01",{"name":44,"class":45},{"id":300,"slug":301,"hasResults":12,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":4,"eligibilityCriteria":305,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":54,"enrollmentInfo":306,"targetDuration":4,"studyType":57,"phases":307,"briefSummary":308,"conditions":309,"keywords":311,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":315,"lastUpdatePostDateStruct":316,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":320,"locationsCount":46},"100567130","analgesic-efficacy-of-quadratus-lumborum-vs-transversalis-fascia-block-in-inguinal-hernia-surgery-100567130","NCT06664177","Analgesic Efficacy of Quadratus Lumborum vs. Transversalis Fascia Block in Inguinal Hernia Surgery","Comparison of the Postoperative Analgesic Efficacy of Quadratus Lumborum Block and Transversalis Fascia Block in Inguinal Hernia Surgery","Inclusion Criteria:\n\n* Ages 18-65\n* ASA Classification 1-2\n\nExclusion Criteria:\n\n* Allergy to local anesthetics\n* Presence of infection at the procedure site\n* BMI \\> 35 kg\u002Fm²\n* Bleeding disorders or anticoagulant use\n* Chronic analgesic or opioid use\n* Mental or psychiatric disorders\n* ASA Classification 3-4 patients(Severe COPD, history of cerebrovascular events, liver and kidney disease will be excluded from the study.)",{"count":166,"type":22},[59],"It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective inguinal hernia surgeries.",[310],"Pain, Postoperative",[312,313,314],"quadratus lumborum block","Transversalis Fascia Plane Block","inguinal hernia","2025-11-24",{"date":297,"type":38},{"date":318,"type":38},"2024-11-01",{"date":37,"type":22},{"name":44,"class":45},{"id":322,"slug":323,"hasResults":12,"nctId":324,"briefTitle":325,"officialTitle":326,"acronym":327,"eligibilityCriteria":328,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":276,"enrollmentInfo":329,"targetDuration":330,"studyType":24,"phases":4,"briefSummary":331,"conditions":332,"keywords":336,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":340,"lastUpdatePostDateStruct":341,"startDateStruct":343,"completionDateStruct":345,"leadSponsor":347,"locationsCount":46},"100612051","timing-of-lng-iud-insertion-and-ovarian-cyst-formation-100612051","NCT07248553","Timing of LNG-IUD Insertion and Ovarian Cyst Formation","The Effect of Levonorgestrel-Containing Intrauterine Device (LNG-IUD) Insertion Timing on Ovarian Cyst Development According to the Early and Late Follicular and Luteal Phases","LNG-IUD TIMING","Inclusion Criteria:\n\n* Reproductive age: 18-45 years\n* Patients with indications for LNG-IUD (levonorgestrel-containing intrauterine device) insertion (abnormal uterine bleeding, menorrhagia, dysmenorrhea, endometriosis, adenomyosis, hormonally induced dysfunctional uterine bleeding, endometrial protection in women receiving postmenopausal hormone replacement therapy, and endouterine hyperplasia without atypia)\n* Patients without contraindications for LNG-IUD (no suspected pregnancy, no serious uterine anomalies (Müllerian anomalies), no active pelvic infection, no history of serious liver disease or breast cancer, and no anatomical or clinical contraindications to IUD insertion) will be included.\n* They must not have used oral contraceptives for at least 3 months.\n* The previous IUD must have been removed at least 1 year prior.\n* Those who signed the informed consent form and agreed to participate voluntarily will be included in the study.\n* Those who have not used steroidal anti-inflammatory drugs within 24 hours of insertion of a levonorgestrel-containing IUD will be included in the study.\n\nExclusion Criteria:\n\n* Pregnancy history or current pregnancy\n* Patients using hormone therapy\n* Patients with adnexal masses\n* Patients with severe systemic diseases (uncontrolled diabetes, advanced cardiovascular disease, active malignancies (especially hormone-sensitive ones), advanced liver or kidney failure, systemic connective tissue diseases)\n* Patients with contraindications to the levonorgestrel IUD (suspected pregnancy, severe uterine anomaly, active pelvic infection, severe liver disease, or a history of breast cancer, anatomical or clinical obstacles to intrauterine device insertion)\n* Patients with psychological disabilities\n* Patients who refuse to sign the informed consent form\n* Patients who cannot be followed up will not be included in the study.",{"count":166,"type":22},"1 Year","In this prospective observational study, the effect of timing of insertion (early\u002Flate follicular; early\u002Flate luteal) on ovarian cyst development in women receiving an LNG-IUD will be assessed ultrasonographically at months 0, 3, 6, and 12. Secondary outcomes include cyst size\u002Fstructure, bleeding pattern, pain, and other adverse events.",[333,334,335],"Ovarian Cysts","Menstrual Cycle","Intrauterine Device (IUD)",[337,338,339],"Levonorgestrel-Releasing Intrauterine Device","Menstrual Cycle Phase","Ovarian Cyst","2025-11-18",{"date":342,"type":38},"2025-11-25",{"date":344,"type":38},"2025-06-01",{"date":346,"type":22},"2026-06-01",{"name":44,"class":45},{"id":349,"slug":350,"hasResults":12,"nctId":351,"briefTitle":352,"officialTitle":353,"acronym":4,"eligibilityCriteria":354,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":355,"enrollmentInfo":356,"targetDuration":4,"studyType":57,"phases":358,"briefSummary":359,"conditions":360,"keywords":367,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":371,"lastUpdatePostDateStruct":372,"startDateStruct":374,"completionDateStruct":375,"leadSponsor":377,"locationsCount":46},"100603619","hemodynamic-effects-of-surgical-position-in-prone-vs-supine-percutaneous-nephrolithotomy-100603619","NCT07138872","Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy","The Effect of Surgical Position on Hemodynamics in Percutaneous Nephrolithotomy Performed in Prone and Supine Positions","Inclusion Criteria:\n\n* ASA physical status I-III\n* Presence of renal calculi indicated for PNL\n\nExclusion Criteria:\n\n* Pregnancy\n* Uncontrolled coagulopathy\n* Previous renal surgery\n* Severe cardiac, pulmonary, or neurological disease\n* Preoperative urinary tract infection (non-sterile urine culture)\n* Surgery duration \\\u003C60 minutes or \\>120 minutes\n* Preoperative blood transfusion\n* Multiple access tracts","80 Years",{"count":357,"type":22},84,[59],"This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.",[361,362,363,364,365,366],"Percutaneous Nephrolithotomy (PCNL)","Surgical Positioning","Prone Position","Supine Position","Hemodynamic Stability","Nephrolithiasis",[368,363,369,364,370,366],"PCNL","Percutaneous Nephrolithotomy","Hemodynamic stability","2025-08-16",{"date":373,"type":38},"2025-08-24",{"date":344,"type":38},{"date":376,"type":22},"2025-12-30",{"name":44,"class":45},{"id":379,"slug":380,"hasResults":12,"nctId":381,"briefTitle":382,"officialTitle":383,"acronym":4,"eligibilityCriteria":384,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":4,"enrollmentInfo":385,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":387,"conditions":388,"keywords":392,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":396,"lastUpdatePostDateStruct":397,"startDateStruct":399,"completionDateStruct":401,"leadSponsor":403,"locationsCount":46},"100602220","ppi-in-weaning-prediction-100602220","NCT07120672","PPI in Weaning Prediction","The Role of Peripheral Perfusion Index as a Predictive Factor During Weaning Process","Inclusion Criteria:\n\n* Patients who have been on mechanical ventilation for at least 48 hours\n* Patients over 18 years of age who are planned to undergo extubation following a spontaneous breathing trial (SBT)\n* Patients or their legal representatives who provide informed consent to participate in the study\n\nExclusion Criteria:\n\n* Patients for whom extubation is not planned due to hemodynamic instability\n* Patients with peripheral vascular disease or a history of hand surgery\n* Patients who die or cannot be followed up during the study period",{"count":386,"type":22},100,"The aim of this study is to evaluate the predictive role of the Peripheral Perfusion Index (PPI) in forecasting extubation success during the weaning process in intensive care unit (ICU) patients. The study will investigate the ability of PPI to predict extubation failure by comparing it with traditional weaning criteria, including the Rapid Shallow Breathing Index (RSBI), PaO₂\u002FFiO₂ ratio, and respiratory rate.",[389,390,391],"Perfusion Index","Weaning of Mechanical Ventilation","ICU",[393,394,395],"perfusion index","weaning","ıcu","2025-08-06",{"date":398,"type":38},"2025-08-13",{"date":400,"type":38},"2025-05-08",{"date":402,"type":22},"2025-08-30",{"name":44,"class":45},{"id":405,"slug":406,"hasResults":12,"nctId":407,"briefTitle":408,"officialTitle":409,"acronym":410,"eligibilityCriteria":411,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":120,"enrollmentInfo":412,"targetDuration":4,"studyType":57,"phases":413,"briefSummary":414,"conditions":415,"keywords":417,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":420,"lastUpdatePostDateStruct":421,"startDateStruct":423,"completionDateStruct":425,"leadSponsor":427,"locationsCount":82},"100601710","vnotes-approach-in-mesh-free-sacrocolpopexy-a-functional-and-anatomic-evaluation-100601710","NCT07114029","VNOTES Approach in Mesh Free Sacrocolpopexy: A Functional and Anatomic Evaluation","Anatomic and Functional Comparison of Preoperative and Postoperative Outcomes of Mesh Free Sacrocolpopexy Performed Via Vaginal Natural Orifice Transluminal Endoscopic Surgery (VNOTES)","vnotes","Inclusion Criteria:\n\nPatients who applied to Gaziosmanpasa Education and Research Hospital, Gynecology and Obstetrics Clinic, have apical and anterior POP Q stage 2 and above, and have undergone surgery due to symptomatic pelvic organ prolapse, Patients who are over the age of 18 and who are citizens of the Republic of Turkey, and who have undergone surgery by experienced surgeons will be included in the study.\n\nExclusion Criteria:\n\nHaving previously received KT and\u002For RT due to any malignancy Having previously undergone surgery due to prolapse Patients with severe cardiovascular or respiratory diseases will not be included in the study.",{"count":5,"type":22},[59],"This study aims to evaluate the effectiveness of mesh-free sacrocolpopexy performed using the VNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery) technique in the surgical treatment of pelvic organ prolapse. Anatomical and functional outcomes will be assessed over a 6-month period before and after the operation. Evaluation tools will include the Pelvic Floor Distress Inventory-20 (PFDI-20), Pelvic Organ Prolapse Quantification (POP-Q) system, and the Pelvic Organ Prolapse\u002FUrinary Incontinence Sexual Questionnaire (PISQ-12).\n\nThe findings of this study are expected to provide important data on the anatomical improvement, functional outcomes, and impact on sexual function of mesh-free sacrocolpopexy performed via the VNOTES approach.",[416],"Pelvic Organ Prolapse",[418,419],"sacrocolpopexy","mesh-free","2025-08-03",{"date":422,"type":38},"2025-08-11",{"date":424,"type":38},"2025-07-01",{"date":426,"type":22},"2026-01-01",{"name":44,"class":45},{"id":429,"slug":430,"hasResults":12,"nctId":431,"briefTitle":432,"officialTitle":433,"acronym":434,"eligibilityCriteria":435,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":436,"enrollmentInfo":437,"targetDuration":4,"studyType":57,"phases":439,"briefSummary":440,"conditions":441,"keywords":443,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":420,"lastUpdatePostDateStruct":446,"startDateStruct":448,"completionDateStruct":449,"leadSponsor":450,"locationsCount":46},"100597332","comparison-of-vnotes-and-laparoscopic-salpingectomy-in-the-surgical-treatment-of-ectopic-pregnancy-100597332","NCT07057115","Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy","Comparison of vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery) Salpingectomy and Laparoscopic Salpingectomy Performed for Ectopic Pregnancy","vNOTES","Inclusion Criteria:\n\nWomen diagnosed with ectopic pregnancy Without heterotopic pregnancy Women aged 18-55 years, within reproductive age Patients for whom medical treatment is not appropriate Patients requiring surgical intervention Patients without systemic diseases that may contraindicate surgery Patients who have signed and approved the informed consent form to participate in the study\n\nExclusion Criteria:\n\nEctopic pregnancy cases that can be treated with medical therapy Patients with advanced pelvic infections or pelvic anatomical abnormalities Patients with immunodeficiency or systemic diseases that contraindicate surgery","55 Years",{"count":438,"type":22},56,[59],"This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.",[442],"Ectopic Pregnancy",[434,444,445],"laparoscopy","salpingectomy",{"date":447,"type":38},"2025-08-05",{"date":424,"type":38},{"date":346,"type":22},{"name":44,"class":45},{"id":452,"slug":453,"hasResults":12,"nctId":454,"briefTitle":455,"officialTitle":456,"acronym":457,"eligibilityCriteria":458,"healthyVolunteers":12,"sex":91,"minAge":225,"maxAge":120,"enrollmentInfo":459,"targetDuration":4,"studyType":57,"phases":461,"briefSummary":462,"conditions":463,"keywords":465,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":471,"startDateStruct":473,"completionDateStruct":474,"leadSponsor":475,"locationsCount":46},"100598463","transperineal-ultrasound-evaluation-of-vesicourethral-angle-and-de-novo-sui-after-colpocleisis-surgery-100598463","NCT07071818","Transperineal Ultrasound Evaluation of Vesicourethral Angle and de Novo SUI After Colpocleisis Surgery","Evaluation of the Vesicourethral Angle by Preoperative and Postoperative Transperineal Ultrasound in Patients Undergoing Colpocleisis Surgery and Assessment of de Novo Urinary Incontinence","colpocleisis","Inclusion Criteria:\n\nPostmenopausal women with stage 3 or 4 pelvic organ prolapse (according to POP-Q score), who are not sexually active and do not desire future vaginal intercourse, and who consent to undergo colpocleisis surgery will be included in the study.\n\nExclusion Criteria:\n\nThose with a history of stress incontinence surgery Those who underwent an additional vesicourethral intervention in addition to colpocleisis surgery Those who wanted sexual intercourse",{"count":460,"type":22},31,[59],"This prospective observational study aims to evaluate changes in the vesicourethral angle using transperineal ultrasound before and after colpocleisis surgery, and to assess the relationship of these changes with the development of de novo stress urinary incontinence.",[464],"Prolapse, Vaginal",[466,467,468,469],"Colpocleisis","Transperineal Ultrasound","de Novo Incontinence","Vesicourethral Angle","2025-07-15",{"date":472,"type":38},"2025-07-17",{"date":424,"type":38},{"date":426,"type":22},{"name":44,"class":45},{"id":477,"slug":478,"hasResults":12,"nctId":479,"briefTitle":480,"officialTitle":481,"acronym":482,"eligibilityCriteria":483,"healthyVolunteers":12,"sex":91,"minAge":484,"maxAge":54,"enrollmentInfo":485,"targetDuration":4,"studyType":57,"phases":487,"briefSummary":488,"conditions":489,"keywords":491,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":494,"startDateStruct":496,"completionDateStruct":497,"leadSponsor":498,"locationsCount":46},"100598142","post-hysterectomy-vaginal-length-horizontal-vs-vertical-closure-100598142","NCT07067645","Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical Closure","Investigation of the Effect of Horizontal and Vertical Vaginal Cuff Closure on Postoperative Total Vaginal Length in Patients Undergoing Vaginal Hysterectomy and Lateral Suspension","vagina","Inclusion Criteria:\n\n* Cases with vaginal hysterectomy and lateral suspension surgery due to stage 3-4 uterine prolapse Agree to participate in the study and sign the informed consent form\n\nExclusion Criteria:\n\n* Cases that have previously undergone a different suspension surgery due to descent uteri (vaginal hysterectomy and sacrospinous ligament fixation surgery, vaginal hysterectomy and sacrocolopexy surgery, vaginal hysterectomy and high sacouterin plication surgery) Cases that have undergone vaginal hysterectomy due to malignancy Cases that have undergone radiotherapy due to malignancy (brachytherapy) Patients who are not suitable for surgical intervention due to severe vaginal atrophy.\n\nPatients who will not be able to comply with the follow-up process. Not accepting to participate in the study or not signing the informed consent form","35 Years",{"count":486,"type":22},62,[59],"This prospective clinical study aims to evaluate the impact of vaginal cuff closure orientation-horizontal versus vertical-on postoperative total vaginal length in patients undergoing vaginal hysterectomy combined with lateral suspension. By comparing anatomical outcomes between the two closure techniques, the study seeks to determine which method better preserves vaginal length, potentially influencing surgical preferences and postoperative quality of life.",[464,490],"Vaginal Vault Prolapse",[492,493],"Vault suspension","vaginal length",{"date":495,"type":38},"2025-07-16",{"date":424,"type":38},{"date":242,"type":22},{"name":44,"class":45},{"id":500,"slug":501,"hasResults":12,"nctId":502,"briefTitle":503,"officialTitle":504,"acronym":4,"eligibilityCriteria":505,"healthyVolunteers":12,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":506,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":508,"conditions":509,"keywords":514,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":519,"lastUpdatePostDateStruct":520,"startDateStruct":522,"completionDateStruct":523,"leadSponsor":525,"locationsCount":4},"100590941","low--vs-normal-flow-anesthesia-and-delirium-after-hip-fracture-in-the-elderly-100590941","NCT06973967","Low- vs. Normal-Flow Anesthesia and Delirium After Hip Fracture in the Elderly","Evaluation of the Association Between Low-Flow and Normal-Flow Anesthesia and Postoperative Delirium in Elderly Patients Undergoing Hip Fracture Surgery","Inclusion Criteria:\n\nPatients aged 65 years and older who are scheduled to undergo surgical treatment for hip fracture, classified as ASA physical status I-IV, and who have signed the informed consent form will be included in the study.\n\nExclusion Criteria:\n\nPatients with complex fractures (multiple fractures, extremity, abdominal, pelvic or sacral trauma, head trauma, etc.), those with relative contraindications to general anesthesia (e.g., known difficult airway, malignant hyperthermia), patients requiring postoperative intubated intensive care follow-up, those with a history of dementia, sleep disorders, or psychosis, individuals with serious neurological diseases (e.g., Parkinson's disease, stroke sequelae), those with a history of opioid, alcohol, or substance use, patients with cerebrovascular disease, those who underwent surgery within the past 6 months, patients with hearing or vision impairment, bleeding disorders or those taking medications affecting coagulation, patients with hypoalbuminemia (\\\u003C3 g\u002FdL), preoperative anemia with hematocrit \\\u003C30%, known allergy to anesthetic drugs, severe cardiopulmonary failure, immobility, malnutrition, or those who are unable to comply with the study protocol will be excluded from the study.",{"count":507,"type":22},128,"The aim of this study is to investigate the relationship between low-flow and normal-flow anesthesia techniques and the development of postoperative delirium in elderly patients undergoing surgery for hip fracture.",[510,511,512,513],"Delirium - Postoperative","Low Flow Anesthesia","Elderly Patients (>65 Years)","Hip Surgery",[515,516,517,518],"delirium","hip surgery","elderly patients","low-flow anesthesia","2025-05-14",{"date":521,"type":38},"2025-05-15",{"date":400,"type":22},{"date":524,"type":22},"2025-08-07",{"name":44,"class":45},{"id":527,"slug":528,"hasResults":12,"nctId":529,"briefTitle":530,"officialTitle":531,"acronym":4,"eligibilityCriteria":532,"healthyVolunteers":12,"sex":17,"minAge":194,"maxAge":92,"enrollmentInfo":533,"targetDuration":4,"studyType":57,"phases":534,"briefSummary":535,"conditions":536,"keywords":538,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":543,"lastUpdatePostDateStruct":544,"startDateStruct":546,"completionDateStruct":548,"leadSponsor":550,"locationsCount":46},"100585182","effects-of-hydrotherapy-in-children-with-cerebral-palsy-100585182","NCT06899035","Effects of Hydrotherapy in Children With Cerebral Palsy","Evaluation of the Effects of Hydrotherapy on Balance and Selective Motor Control in Children With Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosed with Cerebral Palsy by a specialist physician\n* Aged between 4-18 years\n* Cooperative with physiotherapy applications\n* Gross Motor Function Classification System (GMFCS) levels 1-4\n* Willing to participate in the study and undergo assessments\n\nExclusion Criteria:\n\n* Mental retardation or insufficient cognitive function to comply with study assessments\n* GMFCS level 5\n* Presence of an intrathecal baclofen pump for spasticity treatment or history of soft tissue and\u002For bone surgery\n* Active infection or localized skin infection at the injection site\n* History of active seizures\n* Presence of contractures\n* Serious systemic disease that may prevent exercise participation\n* Injury and\u002For surgery within the last 6 months\n* Botulinum toxin injection within the last 6 months\n* Contraindications to hydrotherapy, including severe fear of water, behavioral problems, shortness of breath at rest, infection, incontinence, known chlorine allergy, open wounds, acute systemic illness, epilepsy, tracheostomy, permanent drains, immunodeficiency.",{"count":197,"type":22},[59],"The goal of this observational study is to learn the effects of hydrotherapy in children with cerebral palsy. It aims to answer if hydrotherapy is affective on balance and selective motor control of the children with cerebral palsy.",[537],"Cerebral Palsy Children",[67,539,540,541,542],"rehabilitation","balance","selective motor control","cerebral palsy","2025-03-26",{"date":545,"type":38},"2025-03-27",{"date":547,"type":38},"2025-01-22",{"date":549,"type":22},"2025-12-15",{"name":44,"class":45},{"id":552,"slug":553,"hasResults":12,"nctId":554,"briefTitle":555,"officialTitle":556,"acronym":4,"eligibilityCriteria":557,"healthyVolunteers":224,"sex":17,"minAge":92,"maxAge":54,"enrollmentInfo":558,"targetDuration":4,"studyType":57,"phases":559,"briefSummary":560,"conditions":561,"keywords":564,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":568,"lastUpdatePostDateStruct":569,"startDateStruct":571,"completionDateStruct":572,"leadSponsor":573,"locationsCount":46},"100567132","efficacy-of-variable-volume-truncal-blocks-in-upper-limb-orthopedic-surgery-100567132","NCT06664203","Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery","Comparison of the Anesthetic and Analgesic Efficacy of Selective Truncal Blocks at Different Volumes in Upper Extremity Orthopedic Surgeries","Inclusion Criteria:\n\n* ASA 1-2\n* Body Mass Index (BMI) of 18-35 kg\u002Fm²\n* Age: 18-65 years -Patients undergoing all upper extremity orthopedic surgeries, except shoulder surgeries (distal humerus, elbow, forearm, hand, and wrist), will be included. -\n\nExclusion Criteria:\n\n* Patient refusal\n* Pregnancy or breastfeeding\n* Severe pulmonary disease\n* Contralateral diaphragm paralysis\n* Nerve injury secondary to trauma\n* Neuromuscular disease\n* Peripheral neuropathy\n* Bleeding diathesis\n* Allergy to local anesthetics and dexamethasone\n* Uncontrolled diabetes mellitus\n* Morbid obesity with BMI \\>35\n* Severe cardiovascular, renal, or hepatic disease\n* Infection at the site of the nerve block",{"count":166,"type":22},[59],"aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist, forearm, and elbow surgeries. Completing the operation under regional anesthesia will be considered a successful block.",[562,563],"Pain Management","Anaesthesia Complication",[565,566,567],"postoperative pain","selective turuncus block","arm anaesthesia","2025-03-02",{"date":570,"type":38},"2025-03-05",{"date":318,"type":38},{"date":297,"type":22},{"name":44,"class":45},{"id":575,"slug":576,"hasResults":12,"nctId":577,"briefTitle":578,"officialTitle":579,"acronym":4,"eligibilityCriteria":580,"healthyVolunteers":12,"sex":17,"minAge":92,"maxAge":120,"enrollmentInfo":581,"targetDuration":4,"studyType":57,"phases":583,"briefSummary":584,"conditions":585,"keywords":588,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":596,"lastUpdatePostDateStruct":597,"startDateStruct":599,"completionDateStruct":601,"leadSponsor":602,"locationsCount":46},"100580637","effects-of-hydrotherapy-on-unilateral-lower-extremity-lymphedema-100580637","NCT06839885","Effects of Hydrotherapy on Unilateral Lower Extremity Lymphedema","Evaluation of the Effects of Hydrotherapy on Lower Extremity Volume, Quality of Life, and Functionality in Patients Diagnosed With Unilateral Lower Extremity Lymphedema","Inclusion Criteria:\n\n* Patients with primary or secondary unilateral lower extremity lymphedema diagnosis\n* Patients who have received at least 2 weeks of complex decongestive therapy in the past\n* Patients who are cooperative with hydrotherapy treatments\n* Patients who are willing to participate in the treatment\n* Patients aged 18-75\n\nExclusion Criteria:\n\n* Patients who are unable to perform the evaluation parameters\n* Patients with serious systemic diseases that may prevent exercise\n* Patients who have had an injury and\u002For surgery in the last 6 months\n* Conditions where hydrotherapy is contraindicated (severe fear of water, behavioral problems, shortness of breath at rest, incontinence, known chlorine allergy, open wound, acute systemic illness, epilepsy, tracheostomy, permanent drain, immunodeficiency)\n* Patients with an active infection anywhere in the body\n* Patients who have undergone sentinel lymph node biopsy\n* Patients with active metastatic disease",{"count":582,"type":22},52,[59],"Lymphedema is a chronic condition that negatively affects patients' quality of life and lower extremity functions, causing swelling and a feeling of heaviness in the extremity, as well as posing an economic burden. The gold standard in lymphedema treatment is complex decongestive therapy.Manual lymphatic drainage, skin care, the use of compression garments, and home exercise programs play an important role. Exercise therapies lead to a reduction in volume and an improvement in functionality and quality of life in patients with lymphedema. However, studies on this subject have mostly focused on upper extremity lymphedema. This study aims to compare the effects of a home exercise program and hydrotherapy combined with a home exercise program on quality of life, lower extremity functionality, exercise capacity, and edema severity in patients with unilateral lower extremity lymphedema",[586,587],"Lower Limb Lymphedema","Unilateral Leg Edema",[589,590,591,592,593,594,595],"Aerobic exercise","Hydrotherapy","Functionality","Gynecological cancer","Lymphedema","Exercise capacity","Quality of life","2025-02-17",{"date":598,"type":38},"2025-02-21",{"date":600,"type":38},"2024-12-15",{"date":549,"type":22},{"name":44,"class":45},{"id":604,"slug":605,"hasResults":12,"nctId":606,"briefTitle":607,"officialTitle":608,"acronym":4,"eligibilityCriteria":609,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":610,"enrollmentInfo":611,"targetDuration":4,"studyType":57,"phases":613,"briefSummary":614,"conditions":615,"keywords":617,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":621,"lastUpdatePostDateStruct":622,"startDateStruct":624,"completionDateStruct":626,"leadSponsor":627,"locationsCount":46},"100577718","evaluation-of-perioperative-cystoscopy-and-methylene-blue-test-in-detecting-complications-in-tvt-and-tot-procedures-100577718","NCT06801938","Evaluation of Perioperative Cystoscopy and Methylene Blue Test in Detecting Complications in TVT and TOT Procedures","Comparison of Complications Detected by Perioperative Cystoscopy Combined With Methylene Blue Test and Postoperative Cystoscopy in TVT and TOT Operations","Inclusion Criteria:\n\n* Providing consent to participate in the study\n* Being between the ages of 18 and 85\n* Having stress urinary incontinence\n* No active cardiac disease\n* No connective tissue disorders (e.g., Marfan syndrome)\n* No known gynecological malignancy\n* BMI under 30\n* No chronic constipation\n* No inflammatory bowel disease\n\nExclusion Criteria:\n\n* Not providing consent to participate in the study\n* Being under 18 or over 85 years old\n* Not having stress urinary incontinence\n* Having active cardiac disease\n* Having connective tissue disorders (e.g., Marfan syndrome)\n* Having a known gynecological malignancy\n* Having a BMI over 30\n* Having chronic constipation\n* Having inflammatory bowel disease","85 Years",{"count":612,"type":22},58,[59],"Comparison of complications detected by perioperative cystoscopy combined with methylene blue test and postoperative cystoscopy in TVT and TOT operations.",[616],"Incontinence Stress",[618,619,620],"tvt","tot","cystoscopy","2025-02-04",{"date":623,"type":38},"2025-02-06",{"date":625,"type":38},"2025-01-01",{"date":426,"type":22},{"name":44,"class":45},{"id":629,"slug":630,"hasResults":12,"nctId":631,"briefTitle":632,"officialTitle":633,"acronym":4,"eligibilityCriteria":634,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":120,"enrollmentInfo":635,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":636,"conditions":637,"keywords":638,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":641,"lastUpdatePostDateStruct":642,"startDateStruct":644,"completionDateStruct":646,"leadSponsor":647,"locationsCount":46},"100577761","comparison-of-postoperative-outcomes-of-laparoscopic-lateral-suspension-and-v-notes-lateral-suspension-with-the-salman-ketenci-gencer-technique-100577761","NCT06802497","Comparison of Postoperative Outcomes of Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension With the Salman Ketenci Gencer Technique","Comparison of Early Postoperative Outcomes of Patients Undergoing Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension With the Salman Ketenci Gencer Technique","Inclusion Criteria:\n\n* Patients with stage 3 or 4 pelvic organ prolapse Sexually active patients\n\nExclusion Criteria:\n\n* Cervical pathology History of loop electrosurgical excision procedure (LEEP) or conization Presence of vaginal, pelvic, or adnexal mass Suspicious abdominal malignancy Morbid obesity Any pelvic infection Signs of pregnancy",{"count":357,"type":22},"Comparison of Early Postoperative Outcomes of Patients Undergoing Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension with the Salman Ketenci Gencer Technique",[416],[444,639,640],"v-notes lateral suspension","pelvic organ prolapse","2025-01-25",{"date":643,"type":38},"2025-01-31",{"date":645,"type":38},"2024-07-12",{"date":297,"type":22},{"name":44,"class":45},{"id":649,"slug":650,"hasResults":12,"nctId":651,"briefTitle":652,"officialTitle":652,"acronym":4,"eligibilityCriteria":653,"healthyVolunteers":12,"sex":91,"minAge":92,"maxAge":120,"enrollmentInfo":654,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":656,"conditions":657,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":659,"lastUpdatePostDateStruct":660,"startDateStruct":662,"completionDateStruct":664,"leadSponsor":666,"locationsCount":46},"100539749","comparison-of-five-year-survival-and-disease-free-survival-in-patients-diagnosed-with-endometrium-cancer-who-underwent-total-laparoscopic-hysterectomy-with-and-without-uterine-manipulator-100539749","NCT06307886","Comparison of Five-year Survival and Disease-free Survival in Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With and Without Uterine Manipulator","Inclusion Criteria:\n\n* patients suitable for laparoscopic surgery patients ages 18-75 patients diagnosed figo stage 1 and 2 endometrial cancer\n\nExclusion Criteria:\n\n* patients not suitable for laparoscopic surgery patients diagnosed figo stage 3 and 4 endometrial cancer pregnant patients",{"count":655,"type":22},108,"Comparison of five-year survival and disease-free survival in patients diagnosed with endometrium cancer who underwent total laparoscopic hysterectomy with and without a uterine manipulator",[658],"Endometrial Cancer","2025-01-04",{"date":661,"type":38},"2025-01-07",{"date":663,"type":38},"2023-09-01",{"date":665,"type":22},"2028-09-01",{"name":44,"class":45},""]