[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"George Mason University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":240},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,47,78,102,135,160,185,212],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100642138","brief-inhibitory-training-for-eating---intervention-100642138",false,"NCT07592728","Brief Inhibitory Training for Eating - Intervention","Inhibitory Control Training for Adolescents","BITE-I","Inclusion Criteria:\n\n* 14-17 years old\n* Have overweight or obesity (BMI-z≥85th percentile)\n* Have a smartphone\n* Can read and speak English\n* Interest in improving one's diet.\n\nExclusion Criteria:\n\n* Not currently in eating disorder or weight loss treatment or receiving pharmacological\u002Fsurgical treatment for obesity in the past four weeks\n* Not meeting criteria for atypical anorexia nervosa or bulimia nervosa","ALL","14 Years","17 Years",{"count":21,"type":22},36,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this study is to conduct a proof-of-concept intervention of daily inhibitory control (IC) training.\n\nAim 1 is to examine the feasibility, acceptability, and barriers of an IC training EMI in adolescents' daily life.\n\nAim 2 is to evaluate the efficacy of IC training for modifying the hypothesized intervention mechanism: food-related IC and eating regulation.\n\nIn the study, participants will:\n\nComplete questionnaires and cognitive tasks Receive a short nutrition education Complete three weeks of daily brain games on your phone",[28],"Overweight and\u002For Obesity",[30,31,32,33],"obesity","adolescent","nutrition","eating behavior","RECRUITING","2026-06-15",{"date":37,"type":38},"2026-06-17","ACTUAL",{"date":40,"type":38},"2026-05-01",{"date":42,"type":22},"2027-03-10",{"name":44,"class":45},"George Mason University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100634891","randomized-controlld-trial-of-dementia-education-resources-for-action-100634891","NCT07545577","Randomized Controlld Trial of Dementia Education Resources for Action","Evaluation of Dementia Education and Resources for Action","DERA","Inclusion Criteria:\n\n* Age 18 years or older\n* Currently working as a community health worker or serving in a community health worker-related role\n* Able to read and understand English\n* Has access to the internet and a computer, tablet, or smartphone to complete the online training and surveys\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Previously completed the DERA training program\n* Unable to complete study procedures in English\n* Unable to access the online training platform or study surveys",true,"18 Years",{"count":58,"type":22},100,[25],"The goal of this intervention trial is to evaluate the effectiveness the online training program Dementia Education and Resources for Action (DERA) in improving Alzheimer's disease and related dementia-(ADRD) knowledge, stigma, and service-related self-efficacy among community health workers (CHWs). We hypothesize that participants who have completed the DERA will have improved ADRD knowledge and self-efficacy in related service and reduced stigma against ADRD and people affected.",[62],"Alzheimer's Disease and Related Dementia",[64,65,66,67,68],"Community Health Workers","ADRD","Self-efficacy","Stigma","Digital Health Intervention","NOT_YET_RECRUITING","2026-05-07",{"date":72,"type":38},"2026-05-12",{"date":74,"type":22},"2026-04-16",{"date":76,"type":22},"2026-08-31",{"name":44,"class":45},{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100634412","wellness-enhancement-for-caregivers-100634412","NCT07539350","Wellness Enhancement for Caregivers","WECARE: A Personalized Intervention for Underserved Chinese American Dementia Caregivers","WECARE","Inclusion Criteria:\n\n1. currently residing in the United States,\n2. self-identify as Chinese or Chinese American and are able to read in Chinese,\n3. are 21 years of age or older,\n4. own a cellphone and use WeChat, and\n5. provide at least 8 hours of care per week to a family member or loved one with ADRD.\n\nExclusion Criteria:\n\n(1) evidence of severe cognitive impairment or mental disorders, or (2) the care recipient was receiving hospice care or had a life expectancy of fewer than six months.","21 Years","100 Years",{"count":89,"type":22},160,[25],"The purpose of this study is to test WECARE, a seven-week multimedia intervention designed to reduce psychosocial distress and provide education and support for caregivers. This study will include Chinese American family caregivers of persons living with Alzheimer's disease and related dementias. Participants will engage with digital learning materials and supportive resources over the course of the program. The goal is to determine whether this approach improves caregiver well-being and reduces stress related to caregiving.",[93],"Caregiver Burden","2026-04-13",{"date":96,"type":38},"2026-04-20",{"date":98,"type":22},"2026-09",{"date":100,"type":22},"2030-10",{"name":44,"class":45},{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":46},"100601046","evaluating-conversational-artificial-intelligence-for-depression-management-100601046","NCT07105397","Evaluating Conversational Artificial Intelligence for Depression Management","1. Participant is between 18 to 85 years old.\n2. Participant has been, or are likely to be, diagnosed with moderate to severe Major Depressive Disorder without signs of bipolar depression.\n3. Participant is not in active suicidal crisis and do not face imminent risk of suicide within the next 3 hours.\n4. Participant is not pregnant or seeking to be pregnant.\n5. Participant able to communicate in English on the Internet.\n6. Participant must reside in the United States.\n7. Participant has access to a mental health clinician, or the participant is willing to see study clinicians to help review the advice and medication adjustments recommended by the AI Intake System to the participant.\n8. If the participant is seeing study clinicians, the participant must reside in a state where study clinicians are licensed.\n9. Participant must be using a device (phone or computer) that is located in the United States.","85 Years",{"count":110,"type":22},130,[25],"The goal of this clinical trial is to evaluate how a conversational method of collecting medical history affects patients' perceptions and experiences compared to clinical care as usual. This conversational AI intake system collects medical history information, can be completed by participants at home, and do not disrupt routine clinical care.\n\nThe primary questions this study aims to answer are:\n\n1\\) Does conversational intake affect patients' perceptions of empathy during their clinical interactions?\n\nThis will be a prospective study that follows a cohort of participants for four (4) months after engaging with the AI intake system. Because each participant serves as his\u002Fher own control, both comparators will be administered within-subject, and the order of exposure (AI intake vs. usual care) will be randomized to minimize sequence effects.\n\nAfter completing the AI intake method, participants will rate their experience, particularly in terms of empathy and compare it to their usual interactions with their own clinicians.",[114],"Major Depressive Disorder (MDD)",[116,117,118,119,120,121,122,123,124,125,126],"major depression","antidepressant","large language model","conversational agent","artificial intelligence","AI","NLP","major depressive disorder","medical record augmented generation","patient simulation","testbed","2026-04-03",{"date":129,"type":38},"2026-04-09",{"date":131,"type":22},"2026-04-15",{"date":133,"type":22},"2028-06-30",{"name":44,"class":45},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":55,"sex":17,"minAge":143,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":23,"phases":146,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":46},"100625864","an-aging-healthy-intervention-for-older-adults-delivered-by-community-health-workers-in-senior-centers-a-clinical-trial-100625864","NCT07428174","An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial","ageWELL in the Community Together (aCT) Study","aCT","Inclusion Criteria: Eligible participants will be age 60 years and older, registered as a meal program participant at a participating senior center and speak English.\n\nExclusion Criteria: Non-English speakers and older adults who access meal program services in senior centers not participating in the study are not eligible for study participation.","60 Years",{"count":145,"type":22},250,[25],"The aCT Study will develop, implement and evaluate a community health worker (CHW) integrated model of care delivery for older adults that is senior center based. CHW services will be available for older adult participants at three centers, 4 hours per week for 4 months. Three centers will continue usual services. Researchers will compare blood pressure, physical activity levels, fruit\u002Fvegetable consumption and psychosocial outcomes across groups before and after the intervention.",[149],"Healthy Aging",[151],"older adults, community health workers, senior centers","2026-02-17",{"date":154,"type":38},"2026-02-23",{"date":156,"type":22},"2026-04",{"date":158,"type":22},"2026-12",{"name":44,"class":45},{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":164,"acronym":165,"eligibilityCriteria":166,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":167,"targetDuration":4,"studyType":23,"phases":169,"briefSummary":170,"conditions":171,"keywords":173,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":184},"100608270","parca-a-digital-tool-to-improve-justice-and-health-100608270","NCT07199374","PARCA (a Digital Tool) to Improve Justice and Health","Parca","Inclusion Criteria:\n\nAll officers that supervise individuals All individuals on supervision that indicate drug use -\n\nExclusion Criteria:\n\nIndividuals that have poor performance on their job clients have serious mental health disorders\n\n\\-",{"count":168,"type":22},50,[25],"The purpose of this study is to assess the effectiveness of the Probation\u002FParole and Reentry Coach Application (PARCA)-a mobile application that allows justice-involved people to set and manage personal goals to support sustained, successful community supervision. Through this study, we aim to conduct surveys and interviews aimed to gain a better understanding of ways to improve the substance use treatment process, connections between clients and officers, and goal selection and achievement for clients using the PARCA app",[172],"Behavioral Addiction",[174,175],"probation supervision","recovery app","2025-09-26",{"date":178,"type":38},"2025-09-30",{"date":180,"type":38},"2025-03-01",{"date":182,"type":22},"2027-05",{"name":44,"class":45},2,{"id":186,"slug":187,"hasResults":11,"nctId":188,"briefTitle":189,"officialTitle":190,"acronym":4,"eligibilityCriteria":191,"healthyVolunteers":55,"sex":192,"minAge":56,"maxAge":4,"enrollmentInfo":193,"targetDuration":4,"studyType":23,"phases":195,"briefSummary":196,"conditions":197,"keywords":201,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":46},"100526950","prep-intervention-in-prince-georges-county-maryland-100526950","NCT06141408","PrEP Intervention in Prince George's County, Maryland","A Community-based Intervention to Increase PrEP Initiation in Prince George's County, Maryland: Reducing HIV Stigma and Increasing Social Support","Inclusion Criteria:\n\n* Male\n* Black\n* HIV-negative\n* 18 years of age or older\n* Either residing in Prince George's County Maryland, or having a sexual partner in Prince George's County Maryland within the past year.\n\nExclusion Criteria\n\n* HIV Positive\n* Refusal of HIV testing","MALE",{"count":194,"type":22},120,[25],"The goal of the proposed research is to design a peer-based community intervention focused on addressing HIV stigma, and peer support to increase PrEP initiation in Prince George's County, MD. Participants will attend intervention events focused on stigma reduction and building community. Researchers will compare intervention and control group participants to see if there in a difference in PrEP initiation and adherence.",[198,199,200],"Hiv","Mental Health Issue","Support, Family",[202,67,203,204],"HIV","Support","PrEP",{"date":206,"type":38},"2025-10-01",{"date":208,"type":38},"2022-03-31",{"date":210,"type":22},"2026-12-31",{"name":44,"class":45},{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":4,"eligibilityCriteria":218,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":219,"enrollmentInfo":220,"targetDuration":4,"studyType":23,"phases":222,"briefSummary":223,"conditions":224,"keywords":226,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":46},"100336697","effects-of-gait-retraining-on-lower-extremity-biomechanics-100336697","NCT03663790","Effects of Gait Retraining on Lower Extremity Biomechanics","Comparison of the Effects of Gait Modification Strategies on Knee Adduction Moment in Patients With Medial Knee Osteoarthritis: Randomized Controlled Trial","Inclusion Criteria:\n\n* a clinical diagnosis of knee osteoarthritis by a qualified health professional such as an orthopedic surgeon or physical therapist\n* between the ages of 18 and 80\n* able to walk unaided for a minimum of 20 minutes\n\nExclusion Criteria:\n\n* body mass index greater than 35\n* history of lower back, hip or, knee surgery within the last 2 years\n* knee arthroscopy or pharmacological injection in the previous six months\n* neurological, or musculoskeletal conditions affecting ambulation\n* cognitive impairment that would inhibit motor learning\n* use of gait aid, orthotic shoe inserts, or hinged knee brace","80 Years",{"count":221,"type":22},51,[25],"The purpose of this proposed study is to investigate both the acute and chronic response of frontal plane knee moment after gait retraining and to assess the effects on the biomechanics of the contralateral side. Fifty-one patients diagnosed with tibiofemoral joint osteoarthritis (TFJ OA) will be recruited to participate in the proposed study. Participants will complete baseline trials to assess gait kinematic and kinetic parameters. Following baseline, each participant will perform six conditions of the foot progression gait or three conditions of the trunk lean gait modifications to determine which strategy is most effective in reducing frontal plane knee moment. Participants will then be randomized to either the control or experimental group based on their identified preferred strategy.\n\nParticipants will complete eight gait retraining sessions using patient-specific gait modifications (tailored foot progression and tailored lateral trunk lean), or normal gait (control) during the training period. A fading feedback design will be implemented. Real-time haptic biofeedback will be provided on every step during the first two weeks and reduced by 25% every subsequent two weeks. No feedback will be provided during baseline and at testing sessions. Measures of pain and function will also be collected at all testing sessions. Variables of interest include ankle, knee, hip sagittal and frontal plane moments. In addition, sagittal and frontal plane impulse will also be assessed.\n\nDescriptive statistics will be calculated for foot progression angle, trunk lean angle, frontal and sagittal plane hip, knee, and ankle angles as well as moments. Descriptive statistics for frontal plane knee impulse will also be calculated. A multivariate analysis of variance (MANOVA) will be conducted to compare frontal plane knee moment, frontal plane knee impulse and the absolute sagittal plane moment will be compared across three groups at four different time points. Repeated measures analysis of variance (ANOVA) will be conducted to compare both sagittal and frontal plane joint biomechanics for the contralateral limb. The p-value will be set at .05.",[225],"Knee Osteoarthritis",[227,228,229,230,231],"osteoarthritis","biomechanics","gait retraining","real-time biofeedback","knee","2023-10-25",{"date":234,"type":38},"2023-10-26",{"date":236,"type":38},"2018-10-10",{"date":238,"type":22},"2026-10-01",{"name":44,"class":45},""]