[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"German Federal Institute for Risk Assessment\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":102},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100584042","application-of-plant-protection-products-ppp-in-apple-orchards-100584042",false,"NCT06884189","Application of Plant Protection Products (PPP) in Apple Orchards","Pilot Study on the Exposure of Operators, Residents and Workers to Plant Protection Products Used in Apple Orchards and Possible Health Effects","aPPPle","Inclusion Criteria:\n\n* belonging to one of the defined study groups\n* over 18 years of age at the time of recruitment\n* person can understand the language and content of the study requirements\n* person is capable of consenting to participate in the study and has given written consent to participate in the aPPPle study\n* person has health insurance\n\nExclusion Criteria for residents and control:\n\nperson has direct professional contact with the tested substances acetamiprid, dithianon or dodine",true,"ALL","18 Years",{"count":21,"type":22},16,"ESTIMATED","OBSERVATIONAL","The aim of the aPPPle pilot study is to test feasibility and generate first results in preparation for a main study. The aPPPle study will investigate the exposure of operators, workers and residents to plant protection products (PPP) and potential physiological effects on blood biomarkers. The target plants are apple crops, as application occurs at higher altitudes and therefore higher drift\u002Fexposure is expected compared to ground-level application. The substances to be investigated are acetamiprid (an insecticide) and dithianon and dodine (two fungicides).",[26,27,28,29],"Dermal Exposure","Inhalative Exposure","Metabolites in Urine","Effekt Biomarker in Blood",[31,32,33,34],"exposure study","plant protection products","human biomonitoring","effect biomarker","RECRUITING","2025-03-17",{"date":38,"type":39},"2025-03-19","ACTUAL",{"date":41,"type":39},"2025-03-11",{"date":43,"type":22},"2025-12-20",{"name":45,"class":46},"German Federal Institute for Risk Assessment","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":58,"conditions":59,"keywords":69,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},"100540952","cohort-study-on-plant-based-diets-coplant-study-100540952","NCT06323538","Cohort Study on Plant-based Diets (COPLANT Study)","COPLANT","Inclusion Criteria:\n\n* age between 18 and 69 years at recruitment (age-stratified recruitment in four age groups (18 to 29, 30 to 39, 40 to 49 and 50 to 69 years) which should be equally distributed across the four diets)\n* following their current diet for at least one year\n* health insured\n* are willing to have blood taken (adults)\n* are willing and able to complete questionnaires\n* only at Berlin, Jena, Giessen and Karlsruhe sites: pregnant and breastfeeding women were recruited (shortened examination programm)\n* only at the Regensburg, Heidelberg, Bonn and Vienna sites: are neither pregnant nor breastfeeding at the time of recruitment\n* only at Berlin and Karlsruhe sites: children of adult participants (shortened examination programm without collection of blood, urine, and stool)\n* are able to give informed consent to participate in the study\n* have given their consent to participate in the COPLANT study\n\nExclusion Criteria:\n\n* who can no longer be contacted\n* who withdraw their consent to participate in the study","69 Years",{"count":57,"type":22},6000,"The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria. The COPLANT study focuses on vegan (no animal products), vegetarian (no meat and fish, but dairy products and eggs), pescetarian (no meat, but fish) and omnivorous (mixed diet including all possible animal products) diets. The aim of the COPLANT study is to gain new insights on health benefits and risks as well as social, ecological and economic effects of different plant-based diets in comparison to a mixed diet. In addition to a detailed dietary survey using an app adapted to the needs of this study, the baseline examination includes measurements of body composition, bone health, cardiovascular risk factors, diabetes risk, contaminants and lifestyle. For the basic laboratory program, fasting blood, 24-hour urine collection and a stool sample are taken from all study participants. Furthermore, specific aspects of dietary behavior, physical activity and other lifestyle factors are collected via questionnaires. Follow-up studies are planned at intervals of 5, 10 and 20 years after the baseline visit.",[60,61,62,63,64,65,66,67,68],"Dietary Exposure","Diabetes Mellitus, Type 2","Cardiovascular Diseases","Bone Loss","Sustainability","Exposure","Obesity","Vitamin Deficiency","Mineral Deficiency",[70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92],"vegan","vegetarian","pescetarian","omnivor","multicenter cohort","biomarker","vitamins","minerals","bone health","cardiovascular risk","body composition","inflammation","contaminants","diabetes type 2","thyroid gland health","microbiota","metabolomics","adults","children","pregnancy","breast feeding time","mental health","sustainability","2025-02-13",{"date":95,"type":39},"2025-02-14",{"date":97,"type":39},"2024-04-09",{"date":99,"type":22},"2047-03-31",{"name":45,"class":46},8,""]