[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Groupe Hospitalier Mutualiste de Grenoble\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":123},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,74,98],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100631060","prospective-study-to-determine-the-prevalence-of-signs-of-central-sensitization-in-adults-with-asd-without-intellectual-developmental-disorders-100631060",false,"NCT07495761","Prospective Study to Determine the Prevalence of Signs of Central Sensitization in Adults With ASD Without Intellectual Developmental Disorders","Presca : Prospective Study to Determine the Prevalence of Signs of Central Sensitization in Adults With ASD Without Intellectual Developmental Disorders","Presca","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Medical diagnosis of ASD without established intellectual developmental disorder\n3. Patient affiliated with a social security system or beneficiary of such a system\n4. Understanding of written French (good comprehension of self-questionnaire questions)\n5. No objection from the patient to participate in the study\n\nExclusion Criteria:\n\n1. Intellectual developmental disorder that prevents understanding of self-administered questionnaires\n2. Individuals subject to legal or judicial protection measures or unable to express their consent","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","Autism is a neurodevelopmental disorder (NDD) characterized by two key features: persistent deficits in communication and social interaction, and restricted, repetitive patterns of behavior, interests, and activities. Ninety-five percent of children aged 3 to 6 with autism spectrum disorder (ASD) have sensory peculiarities. In adulthood, this figure remains at 90%. This atypical sensory processing has been part of the DSM diagnostic criteria since 2013.\n\nEach sense can be affected by hypo- or hypersensitivity. In the continuum of this particular sensory processing, pain, which is defined as an unpleasant sensory and emotional experience, can be very present but also difficult to detect and manage. It is now established that there are other characteristics that impact pain in ASD: information processing time may be longer, referred to as \"latency time,\" but there are also difficulties in representing the body schema and difficulties in identifying and\u002For interpreting perceptions. Expression may be atypical, and there may be an apparent lack of reaction to pain due to a lack of flexibility.\n\nAll of these characteristics themselves vary over time (with age, the menstrual cycle, lack of sleep, fatigue, etc.), to the point that even pain specialists in pain clinics may not recognize them.\n\nIt is therefore essential to carry out appropriate, individualized assessments.\n\nThe scientific literature refers to the high frequency of painful events in ASD. For example, the prevalence of gastrointestinal disorders with their associated abdominal pain is significantly higher. Recent research has revealed that 82.4% of children and adolescents with ASD have at least one gastrointestinal symptom. Researchers have found that children with ASD are almost eight times more likely to have one or more chronic gastrointestinal symptoms than typically developing children. There are also more common comorbidities that facilitate or maintain chronic pain: Ehler Danlos syndrome and hypermobility spectrum disorders, IBD, ADHD, post-traumatic stress disorder, depression, migraines and tension headaches, anxiety disorders, epilepsy, small fiber pathologies, nutritional deficiencies, musculoskeletal disorders, etc.\n\nMutations in certain genes involved in ASD (such as SCN9A, SHANK3, and CNTNAP2) lead to impaired neuronal function, producing different responses to pain, as demonstrated in both mouse and human models. The links between ASD and chronic pain are therefore complex. Sometimes it is the unusual characteristics of the pain that could lead to a diagnosis of ASD.\n\nThe concept of central sensitization (CS), which underlies the type of pain known as \"nociplastic,\" helps explain the state of pain hypersensitivity and pathologies such as fibromyalgia and irritable bowel syndrome. In 2022, Grant et al. found that 21% of adults with ASD surveyed in the cohort reported having a diagnosis of central sensitization syndrome (CSS), but 60% scored at or above the cut-off. This suggests that CS symptoms such as pain and fatigue are very common in people with autism, and perhaps more prevalent than in the general population. For example, three-quarters of women diagnosed with ASD and\u002For ADHD in childhood report chronic pain in adulthood.\n\nThe issue is the disability associated with this chronic pain and the impairment of quality of life.",[25,26],"Pain Management","Autism Spectrum Disorder (ASD)",[28,29,30,31],"autism spectrum disorder","chronic pain","signs of central sensitization","ASD r without intellectual developmental disorder","RECRUITING","2026-03-24",{"date":35,"type":36},"2026-03-27","ACTUAL",{"date":38,"type":36},"2026-02-04",{"date":40,"type":21},"2027-07-29",{"name":42,"class":43},"Groupe Hospitalier Mutualiste de Grenoble","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100611152","evaluation-of-grampa-score-measuring-motor-abilities-of-elderly-patients-100611152","NCT07236866","Evaluation of GRAMPA Score Measuring Motor Abilities of Elderly Patients","Prospective, Single-center Interventional Study to Assess the Reliability of the GRAMPA Score, Measuring the Graduation of Motor Abilities of the Elderly Patients Hospitalised","GRAMPA","Inclusion Criteria:\n\n1. Age ≥ 75 years\n2. Patients hospitalized in the geriatrics department of the Grenoble Mutualist Hospital Group\n3. Comprehension of the French language (understanding of instructions)\n4. Signature of free and informed consent\n\nExclusion Criteria:\n\n1. Patients whose sensory and\u002For mental capacities do not allow them to understand the instructions for carrying out transfers.\n2. Patients with medical or surgical contraindications making it impossible to carry out transfers.\n3. Patients under legal protection or unable to express their consent.","75 Years",{"count":55,"type":21},55,"INTERVENTIONAL",[58],"NA","In the field of geriatrics, the Standardized Geriatric Approach (SGA) which is the benchmark for assessing elderly patients, consists of evaluating the medical, psychological and functional capacity dimensions of the elderly subject, among others.\n\nAfter a review of the literature, investigators were unable to find any scales that could study the ability to perform basic movements in a comprehensive and graded manner.\n\nScores that do assess certain aspects of motor abilities are not comprehensive, and are often based on self-reporting by the elderly or their relatives :\n\n* The AGGIR grid assesses dependency on the basis of activities performed or not performed. In addition, all basic movements are grouped together in a single item, which does not provide detailed information on the capabilities of elderly people.\n* The ADL score assesses activities of daily living, based on what patients declare. Only one item concerns basic movements, without detailing them.\n* The Tinetti score and Time up and go do not assess all basic movements, and require the patient to be able to stand to provide relevant information, whereas many geriatrics patients are unable to stand.\n\nThus, investigators created a score to assess motor abilities more comprehensively that will include the following basic movements:\n\n* Getting up in bed\n* Turning on one side in bed\n* Sitting at the edge of the bed\n* Stand up\n* Move around a small perimeter (bedroom)\n* Sitting up\n* Return to bed\n\nThe main objective is to evaluate of this study is to determine the inter-rater reliability of the GRAMPA score in elderly patients hospitalized in a geriatrics department.",[61],"Geriatric Assessment",[63,64],"motor skills","rehabilitation","2026-03-16",{"date":67,"type":36},"2026-03-18",{"date":69,"type":36},"2025-11-07",{"date":71,"type":21},"2027-11-01",{"name":42,"class":43},2,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},"100597258","association-between-early-consultation-by-the-primary-care-physician-after-hospitalization-in-geriatric-medicine-department-and-the-risk-of-re-hospitalization-at-1-and-3-months-100597258","NCT07056153","Association Between Early Consultation by the Primary Care Physician After Hospitalization in Geriatric Medicine Department, and the Risk of Re-hospitalization at 1 and 3 Months","GEREHOSP","Inclusion Criteria:\n\n1. Age ≥ 75 years\n2. Patients hospitalized in the geriatric department of one of the investigating centers\n3. Patient discharged home from the geriatrics department of one of the investigating centers\n4. No objection from patient or legal representative to participate in study\n\nExclusion Criteria:\n\n1. Patients who do not have a primary care physician\n2. Patients living in an institution or transferred to an institution",{"count":82,"type":21},301,"The time it takes for patients to be readmitted to hospital is a major public health issue, both in terms of medical time and costs.\n\nIn fact, 15% of patients of all ages are likely to be re-hospitalized within a month of hospitalization.\n\nToday, hospitalizations present a significant nosocomial risk, all the more so in fragile populations. If these hospitalizations are long or repeated, it is crucial to develop solutions to reduce their number.\n\nElderly people often have a number of complementary pathologies and frailties, which are frequently destabilized during hospitalization or on discharge.\n\nIn this context of medico-social and financial stakes, a 2012 survey showed that 86% of French physicians would be prepared to make themselves available within 24-48 hours of hospital discharge if the situation justified it. Changes in medical demographics are forcing primary care physicians to adapt their practices, and the evidence of a reduced risk of re-hospitalization would make it possible to prioritize the provision of this consultation on discharge from hospital.\n\nPost-hospitalization follow-up consultations with the primary care physician are recommended, but investigators have very little data on their benefits.\n\nInvestigators hypothesise that an early consultation (1 month post-hospitalization at most) by an elderly patient's primary care physician after hospitalization in geriatric medicine promotes: patient follow-up; reduced risk of re-hospitalization within 3 months.\n\nThe aim of this study is to determine the association of an early consultation by the primary care physician in the month following discharge from geriatric medicine hospitalization with rehospitalization rates within 3 months.",[85],"Geriatric",[87,88],"primary care physician","early post-hospitalization consultation","2025-07-10",{"date":91,"type":36},"2025-07-15",{"date":93,"type":36},"2025-06-19",{"date":95,"type":21},"2026-03",{"name":42,"class":43},3,{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":56,"phases":108,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":44},"100592070","impact-of-a-counseling-consultation-in-the-workplace-for-smoker-health-professionals-100592070","NCT06988644","Impact of a Counseling Consultation in the Workplace for Smoker Health Professionals","Prospective Study Aimed at Evaluating the Effect of a Counseling Consultation in the Workplace for Smoker Employees in a Mental Health Establishment","PSYTaB","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Health professional\n3. Daily smoker of at least 1 cigarette or joint per day and every day\n4. Willingness to quit smoking\n5. Patient physically able and willing to undertake a carbon monoxyde measurement\n6. Patient affiliated to a social security scheme or beneficiary of such a scheme\n7. Signature of informed consent\n\nExclusion Criteria:\n\n1. Smoking via vaporizer exclusively\n2. Occasional (i.e. not daily) smoker or exhaled carbon monoxyde at inclusion \\\u003C 9 ppm\n3. Resignation, transfer or end of employment contract during the study period (1 year)\n4. Unable to undergo study follow-up for geographical, social or psychological reasons\n5. Persons under legal protection or unable to express their consent.",{"count":107,"type":21},30,[58],"Smoking is still a major cause of premature death in France (75,000 deaths a year). Health professionals also seem to be affected by smoking, but few studies have been carried out on this population of smokers. While having a job can be protective, certain working conditions are at risk: night shifts, stress, physical strain, burnout... In 2010, 23% of nurses and 40% of nursing auxiliaries were smokers. More recently, a study of 10,000 health professionals in a French health establishment in 2022 revealed a rate of 32% among nursing auxiliaries.\n\nData on smoking among health professionals is still scarce. Yet they seem essential, given that smoking among healthcare professionals seems to be an obstacle to dealing with patients' consumption and contributes to the erroneous representations that persist in psychiatry more than elsewhere, such as: \"smoking with a patient makes an alliance with them\", \"smoking is a way of reducing psychological tension\", \"patients have other problems to deal with\", \"it won't work because they've been smoking for years\". Smoking in mental health facilities is high among both patients and professionals.\n\nInvestigators now know that smoking has an impact on mood disorders and sleep. It aggravates all somatic and psychological pathologies and predisposes people to more diabetes, chronic bronchitis, cardiovascular disease, cancer, etc. It also interacts with many drugs.\n\nSmoking screening and cessation assistance have become an indicator of quality somatic care in mental health institutions.\n\nInvestigators hypothesise that a consultation in the workplace can help employees to change their smoking habits.\n\nThe aims of this study are to assess the effect of a workplace smoking clinic on smokers employed in a mental health institution, and to describe their smoking habits and profiles according to occupational category, with a view to implementing appropriate preventive and treatment measures.",[111],"Smoking Cessation",[111,113,114],"Smoking consultation","carbon monoxyde measurement","2025-05-23",{"date":117,"type":36},"2025-05-29",{"date":119,"type":36},"2024-11-11",{"date":121,"type":21},"2026-11-30",{"name":42,"class":43},""]