[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Groupe Hospitalier du Havre\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":152},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,78,103,124],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100630828","effect-of-using-a-reminder-to-encourage-patients-to-be-active-during-their-hospital-stay-100630828",false,"NCT07492745","Effect of Using a Reminder to Encourage Patients to be Active During Their Hospital Stay.","Effect of Using a Reminder to Encourage Patients to be Active During Their Hospital Stay : a Multicenter Randomised Controlled Double Blind Study.","REMOTIVE","Inclusion Criteria:\n\n* Patients aged 50 or over with a score of 4 or above on the Clinical Frailty Scale (vulnerable but not dependent patients, symptoms limiting activities, patients who are slower\u002Fmore fatigued).\n* Must be able to get up from a chair without assistance.\n* Patients must be able to communicate with staff, understand instructions, give consent, and cooperate with staff.\n\nExclusion Criteria:\n\n* Patients with an estimated hospital stay of less than 5 days.\n* Contraindications to physical activity determined by the medical team (e.g., cardiovascular instability, orthopedic contraindications, etc.).\n* Terminal illness.\n* Patients scheduled for surgery.\n* Pregnant women.\n* People who do not understand French.\n* People protected under the law.","ALL","50 Years",{"count":20,"type":21},204,"ESTIMATED","INTERVENTIONAL",[24],"NA","Around 30% of patients aged 65 and over experience functional decline due to hospitalization. Physical inactivity, often without medical justification, is common during hospital stays.This immobility leads to loss of autonomy, muscle strength, and increases post-discharge risks.\n\nSlow walking for 25-40 minutes daily significantly improves functional capacity. However, it could be difficult to reach this time of walking due to a lack of physiotherapist in hospital.\n\nA vibrating watch may encourage patients to walk or perform strengthening exercises. This simple intervention aims to improve function without requiring additional staff or resources",[27,28],"Inpatients","Frail",[30,31,32,33,34],"inpatients","physical activity","reminder device","frailty","functional independancy","RECRUITING","2026-06-15",{"date":38,"type":39},"2026-06-16","ACTUAL",{"date":41,"type":39},"2025-11-19",{"date":43,"type":21},"2029-01-01",{"name":45,"class":46},"Groupe Hospitalier du Havre","OTHER",4,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":59,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100621525","shear-wave-elastography-of-intercostal-muscles-for-the-non-invasive-assessment-of-the-work-of-breathing-100621525","NCT07371754","Shear Wave Elastography of Intercostal Muscles for the Non-invasive Assessment of the Work of BreathinG","SWING","Inclusion Criteria:\n\nAdult patient with chronic obstructive pulmonary disease (COPD), stage 3-4.\n\nHealthy adult volunteer.\n\nExclusion Criteria:\n\nRefusal to participate or withdrawal of consent.\n\nAge \\\u003C 18 years.\n\nBMI \\> 35 kg\u002Fm².\n\nPregnancy or breastfeeding.\n\nInability to understand instructions or cooperate (cognitive impairment, language barrier).\n\nNeurological condition affecting breathing (e.g., recent stroke, ALS, myopathy).\n\nThoracic condition limiting access to the intercostal muscles (e.g., major chest wall deformity, surgical scar).\n\nRecent thoracic or abdominal surgery (\\\u003C 3 months).\n\nKnown esophageal disease (stricture, achalasia, severe esophagitis, diverticulum, history of perforation).\n\nENT or tracheal abnormality preventing probe insertion (e.g., tumor, malformation, tracheostomy).\n\nSwallowing disorders or risk of aspiration.\n\nRecent exacerbation (\\\u003C 6 weeks).\n\nOxygen therapy \\> 2 L\u002Fmin during exertion.\n\nHemodynamic instability.\n\nNot affiliated with a social security scheme.\n\nLegally protected persons (as defined by law).",true,"18 Years",{"count":58,"type":21},20,"1 Day","OBSERVATIONAL","Quantifying respiratory effort is a key step in physiological and clinical research on exercise tolerance, mechanisms of fatigability, and ventilatory impairment. To date, reliable assessment relies on an invasive method: esophageal pressure (Pes) measurement using a balloon catheter inserted into the esophagus. Although Pes provides an indirect estimate of pleural and intrathoracic pressure, it is uncomfortable for patients, requires dedicated equipment, and may limit study participation.\n\nIn critically ill patients, a noninvasive approach to quantify respiratory effort would have major clinical and scientific value. In acute respiratory distress, accurately tracking the intensity and evolution of respiratory effort could support earlier therapeutic decision-making.\n\nShear Wave Elastography (SWE) is an ultrasound technology enabling very high acquisition rates and estimating tissue stiffness from shear-wave propagation induced by an acoustic impulse. Because muscle stiffness is strongly related to force produced during contraction, we hypothesize that intercostal muscle stiffness measured by SWE correlates with respiratory work and increases with rising inspiratory load.",[63,64],"COPD","Healthy Adult",[66,67,68],"Shear wave elastography","Intercostal muscles","work of breathing","NOT_YET_RECRUITING","2026-01-19",{"date":72,"type":39},"2026-01-28",{"date":74,"type":21},"2026-03-01",{"date":76,"type":21},"2027-03-01",{"name":45,"class":46},{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},"100592535","clinimetric-properties-of-muscle-mass-and-stiffness-measurements-of-the-quadriceps-in-patients-with-copd-100592535","NCT06994689","Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD","Clinimetric Properties Assessment of Quadriceps Muscle Mass and Stiffness Using Perimetry and ShearWave Elastography in Patients With COPD : a Prospective Observational Study","Metriquad","Inclusion Criteria:\n\n* COPD patients\n* Adults (\\>18 years old)\n* Patients starting a pulmonary rehabilitation (PR) programme\n\nExclusion Criteria:\n\n* Patients included in other research protocol\n* Minors or under guardianship\n* Pregnancy\n* Patients with lower limb amputation or history of neuromuscular disease\n* Cardiovascular contradications for PR",{"count":87,"type":21},30,"A large amount of patients with COPD suffer from muscle dysfunction characterized by losses of muscle mass and strength. Studies have shown an association between a loss of quadriceps muscle mass and premature death.\n\nThis study aims to investigate the clinimetric properties of a simple quadriceps perimetry and ShearWave elastography to improve the monitoring of skeletal muscle function in patients with COPD.",[63,90],"Quadriceps Muscle Atrophy",[92,93,94],"Clinimetric properties","Muscle mass","Muscle strength",{"date":96,"type":39},"2026-01-21",{"date":98,"type":39},"2025-05-30",{"date":100,"type":21},"2026-12-01",{"name":45,"class":46},1,{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":55,"sex":110,"minAge":56,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":22,"phases":113,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":117,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},"100575470","validation-of-the-french-version-of-the-edinburgh-postnatal-depression-scale-epds-postnatally-in-the-father-100575470","NCT06772701","Validation of the French Version of the Edinburgh Postnatal Depression Scale (EPDS) Postnatally in the Father","EPDS-PERE","Inclusion Criteria:\n\n* All fathers whose baby is 10 days old or less\n\nExclusion Criteria:\n\n* People with a poor understanding of spoken or written French\n* Minors\n* Persons under court protection, guardianship or curatorship","MALE",{"count":112,"type":21},1000,[24],"In recent years, fatherhood has changed considerably. Fathers are now more involved during the perinatal period, with their partner but also in caring for the child. Investigators now know that this period is also a source of major psychological upheaval, identity crisis, apprehension and anxiety for men. These upheavals can lead to depression that must be detected and treated as early as possible. This is an easy screening to perform using the EPDS (Edinburgh Postnatal Depression Scale). Currently, the EPDS is the most widely used self-questionnaire to assess the risk of depression in women during the perinatal period. Indeed, it is systematically recommended in many countries. It is starting to be used for the same purpose in the perinatal period in men, although the scale has not been validated in a representative sample of men in the pre- or post-natal period.\n\nThe main objective is to validate the use of the EPDS scale as a screening tool for postnatal depression in a population of French fathers.\n\nThey complete the PH-Q9, EPDS and socio-demographic questionnaires online at inclusion and 6 to 8 weeks after the birth of their child. Fathers included at the maternity ward also too Mini International Neuropsychiatric Interview (MINI) at inclusion.",[116],"Depression, Postpartum",{"date":96,"type":39},{"date":119,"type":39},"2024-07-11",{"date":121,"type":21},"2027-03-12",{"name":45,"class":46},2,{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":136,"conditions":137,"keywords":139,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":147,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":151,"locationsCount":102},"100535252","the-importance-of-positive-expiratory-pressure-associated-with-the-in-exsufflator-in-als-patients-100535252","NCT06249412","The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in ALS Patients","The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in Patients With Amyotrophic Lateral Sclerosis on the Effectiveness of Therapy","PEPINEX","Inclusion Criteria:\n\n* Male or female patient aged over 18 years\n* Patient with Amyotrophic Lateral Sclerosis (ALS)\n* Patients with established or beginning bulbar disorders, identified by the healthcare team (speech impairment, hypersalivation, or swallowing difficulties)\n* Patient naive to INEX therapy but prescribed for its installation or patient already treated by an INEX device\n* Patient followed by the ALS mobile team of the Groupe Hospitalier du Havre or the CHU of Dijon\n* Patient whose disease progression kinetics is medically deemed compatible with inclusion in the study\n* Patient willing to participate in the research after receiving adequate information and the information letter.\n* Patient affiliated with social security or a beneficiary of such a scheme.\n\nExclusion Criteria:\n\n\"● Patient not presenting an episode of infection or a past episode of respiratory infection less than one month old\n\n* Mental illness interfering with the proper use of the device\n* History of laryngospasm\n* Inability to come for consultation with the ALS team of the Groupe Hospitalier du Havre or the CHU of Dijon\n* Pregnancy\n* Person deprived of liberty by judicial or administrative decision, person subject to a legal protection measure (patient under guardianship or curatorship) Article L1121-8.\n* Appearance of a non-inclusion criterion\n* Refusal to participate after inclusion\n* Death from any cause\"","100 Years",{"count":134,"type":21},11,[24],"Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder that impairs motor neurons, with a life expectancy of 2 to 7 years after diagnosis. ALS manifests as 'spinal' when it primarily affects limbs, or 'bulbar' when it impairs speech and swallowing. The disease progressively weakens all skeletal muscles, causing respiratory issues and increased risk of lung infections due to ineffective coughing. Mechanical cough assistance via In-exsufflation therapy\u002F mechanical in-exsufflator devie (INEX\u002FMI-E) applies positive and negative airway pressures non-invasively to improve coughing. However, MI-E may fail in some ALS patients due to airway collapse, often related to brainstem muscle dysfunction.Research by Andersen et al. in 2017 highlighted that during MI-E, ALS patients often experience adverse laryngeal movements, which can obstruct airways and reduce the therapy's effectiveness. To combat this, they suggested individualized MI-E settings to minimize airway collapse. Modern MI-E devices, such as the EOVE-70, offer adjustable positive expiratory pressure (PEP) between cycles to potentially enhance airway stability and coughing efficiency. The current study focuses on the impact of PEP during therapy pauses on the peak expiratory flow rate in ALS patients, which could lead to improved therapeutic outcomes.",[138],"Amyotrophic Lateral Sclerosis ALS7",[140,141,142,143,144,145,146],"ALS","Amyotrophic Lateral Sclerosis","MI-E therapy","INEX therapy","Airway clearance technics","Neuromuscular disease","Cough assit",{"date":96,"type":39},{"date":149,"type":39},"2024-12-19",{"date":76,"type":21},{"name":45,"class":46},""]