[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hainan Medical College\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":65},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,37],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":4},"100573830","monitoring-salivary-gland-injury-in-nasopharyngeal-carcinoma-patients-after-radiotherapy-using-multi-modal-radiomics-100573830",false,"NCT06751381","Monitoring Salivary Gland Injury in Nasopharyngeal Carcinoma Patients After Radiotherapy Using Multi-Modal Radiomics","A Prospective Study on Monitoring Salivary Gland Injury in Nasopharyngeal Carcinoma Patients After Radiotherapy Using Multi-Modal Radiomics","Inclusion Criteria:\n\n1. Histologically or cytologically confirmed diagnosis of nasopharyngeal carcinoma.\n2. Scheduled to undergo radiotherapy as part of standard treatment.\n3. Aged 18 years or older.\n4. No contraindications to MRI scans (e.g., no implanted metallic devices).\n5. Written informed consent has been provided.\n\nExclusion Criteria:\n\n1. Contraindications to MRI, such as metallic implants or claustrophobia.\n2. Severe comorbid conditions, including significant renal or hepatic dysfunction.\n3. Concurrent participation in another interventional clinical trial.\n4. Pregnant or breastfeeding.\n5. Any condition that may impair compliance with study procedures.","ALL","18 Years",{"count":19,"type":20},45,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the role of intravoxel incoherent motion (IVIM) imaging and magnetic resonance fingerprinting (MRF) techniques in monitoring salivary gland injury in nasopharyngeal carcinoma (NPC) patients undergoing radiotherapy. The study will recruit patients diagnosed with NPC who are receiving standard radiotherapy, and quantitative imaging data will be collected using IVIM and MRF techniques at multiple time points, including pre-treatment, during radiotherapy, and post-treatment. The primary objective is to analyze changes in salivary gland structure and function and to identify early imaging biomarkers indicative of radiation-induced injury. The findings are expected to provide new insights into the dynamic progression of salivary gland damage, establish predictive models for the risk of xerostomia, and guide the development of personalized therapeutic strategies to mitigate long-term complications.",[24],"Nasopharyngeal Carcinoma ,Xerostomia,Radiotherapy","NOT_YET_RECRUITING","2025-01-12",{"date":28,"type":29},"2025-01-14","ACTUAL",{"date":31,"type":20},"2025-01-20",{"date":33,"type":20},"2026-12-06",{"name":35,"class":36},"Hainan Medical College","OTHER",{"id":38,"slug":39,"hasResults":11,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":4,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":16,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":49,"studyType":21,"phases":4,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},"100568819","hainan-community-cognition-cohort-100568819","NCT06686186","Hainan Community Cognition Cohort","A Prospective Cohort of Hainan Community Elderly Population with Cognitive Impairment","* Inclusion Criteria:\n\n  * Age 60 years and above\n  * Lived in the community for more than 6 months\n  * Signed the informed consent form\n* Exclusion Criteria:\n\n  * Cannot complete the survey",true,"60 Years","120 Years",{"count":48,"type":20},2000,"30 Years","This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up. The research aims to identify risk factors as well as health and social outcomes that are associated with cognitive impairment in elderly populations, and independently develop AI-assisted software and applications for cognitive enhancement and physical rehabilitation training.",[52,53,54],"Cognitive Impairment","Dementia","Age Problems","RECRUITING","2024-11-11",{"date":58,"type":29},"2024-11-13",{"date":60,"type":29},"2022-12-16",{"date":62,"type":20},"2053-12-31",{"name":35,"class":36},1,""]