[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Halic University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":301},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,48,79,108,133,163,190,223,248,274],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100643578","osteopathy-in-postpartum-lumbopelvic-pain-100643578",false,"NCT07631949","Osteopathy in Postpartum Lumbopelvic Pain","Effects of Osteopathy on Pain, Function, Quality of Life, Stress Hormones and Inflammatory Biomarkers in Women With Postpartum Lumbopelvic Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Female participants aged 18 to 50 years. History of childbirth within the previous 6 to 15 months. Diagnosis of postpartum lumbopelvic pain confirmed by an obstetrician-gynecologist.\n\nPresence of low back pain and\u002For pelvic girdle pain for at least 3 months according to the European Guidelines for the Prevention of Low Back Pain and the European Guidelines for Pelvic Girdle Pain.\n\nPain intensity of at least 5\u002F10 on the Visual Analog Scale (VAS). Willingness to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* History of low back pain or pelvic girdle pain before pregnancy. Multiple pregnancy (twins or higher-order pregnancy). Receiving other physical therapy interventions or pain-related medication during the study period.\n\nHistory of major trauma. Musculoskeletal injury or fracture. Myofascial pain syndrome. Fibromyalgia. Osteoarthritis. Neurological disorders (e.g., radiculopathy or myelopathy). Chronic inflammatory disease. History of cancer. Osteoporosis. Inability to comply with the study procedures.","FEMALE","18 Years","50 Years",{"count":20,"type":21},45,"ESTIMATED","INTERVENTIONAL",[24],"NA","Postpartum lumbopelvic pain is a common condition after childbirth and may affect pain levels, physical function, daily activities, and quality of life.\n\nConservative treatment options include patient education, exercise, and manual therapy. Although osteopathic manupilative treatment has been shown to improve pain and function in musculoskeletal disorders, limited evidence is available regarding its effects on stress hormone levels and inflammatory biomarkers in women with postpartum lumbopelvic pain.\n\nThis randomized controlled trial aims to investigate the effects of osteopathic manupilative treatment on pain, physical function, quality of life, stress hormone levels, and inflammatory biomarkers among women with postpartum lumbopelvic pain.\n\nParticipants will be randomly assigned to one of three groups: education and core stabilization exercises, education and core stabilization exercises combined with osteopathic manupilative treatment, or education and core stabilization exercises combined with sham osteopathic manupilative treatment. Outcome measures will be assessed before treatment and one week after the final treatment session.",[27,28,29],"Postpartum Lumbopelvic Pain","Postpartum Pelvic Girdle Pain","Postpartum Low Back Pain",[27,31,32,33,34],"Osteopathic Manipulative Treatment","Core Stabilization Exercise","Inflammatory Biomarkers","Cortisol","NOT_YET_RECRUITING","2026-06-02",{"date":38,"type":39},"2026-06-08","ACTUAL",{"date":41,"type":21},"2026-06-01",{"date":43,"type":21},"2026-12-01",{"name":45,"class":46},"Halic University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":78,"locationsCount":4},"100625583","psychosocial-effects-of-mindfulness-based-exercise-in-postmenopausal-women-100625583","NCT07424521","Psychosocial Effects of Mindfulness-Based Exercise in Postmenopausal Women","The Effects of Mindfulness-Based Exercise on Anxiety, Depression, and Sleep Quality in Postmenopausal Women","Inclusion Criteria:\n\n* Volunteering to participate in the study\n* Being in the early postmenopausal period (no more than 8 years have passed since menopause)\n* Having experienced natural menopause\n* Having had at least one pregnancy\n* Residing in Istanbul or Izmir provinces\n\nExclusion Criteria:\n\n* History of trauma or illness that would prevent exercise\n* Having received hormone replacement therapy\n* Being involved in a different exercise program\n* Presence of a severe cardiopulmonary, orthopedic, or neurological disease\n* Presence of a psychological or psychiatric diagnosis\n* Presence of physical discomforts such as severe dizziness\n* Cooperation problems and incompatibility",true,"45 Years","60 Years",{"count":59,"type":21},20,[24],"Menopause is a natural biological process characterized by the permanent cessation of the menstrual cycle in women. Hormonal changes associated with menopause commonly lead to mood swings, anxiety, depression, stress, and decreased sleep quality in women. While the current literature indicates that mindfulness-based interventions offer potential benefits in alleviating psychological and physical symptoms in postmenopausal women, the limited number of studies in the literature and methodological differences suggest a need for more randomized controlled trials in this area. The aim of this study is to examine the effect of mindfulness-based exercises on psychosomatic complaints such as anxiety, depression, and sleep quality in postmenopausal women. Designed as a randomized controlled experimental study, it was planned to include at least 20 women in the early postmenopausal period residing in Istanbul and Izmir between March and June 2026. The women included in the study will be randomized into Group 1 (n=10), which will perform mindfulness-based exercises, and Group 2 (n=10), which will receive no intervention as usual. The STAI I-II Form State and Trait Anxiety Scale and Beck Anxiety Inventory will be used to assess state and anxiety level, the Beck Depression Scale for depression level, and the Pittsburgh Sleep Quality Scale for sleep quality.\n\nContinuous variables will be presented as mean ± standard deviation, and qualitative variables as number and percentage (%). If parametric test assumptions are met, the Independent Samples t-test will be used to compare independent groups, and the Paired Samples t-test will be used to compare dependent groups. If parametric test assumptions are not met, the Mann-Whitney U test will be used to compare independent groups, and the Wilcoxon test will be used to compare dependent groups. Statistical significance will be set at p≤0.05. This study is expected to contribute to the literature by providing evidence-based data on the effectiveness of mindfulness-based exercises on common psychological symptoms in the postmenopausal period.",[63,64,65],"Psychosocial Functioning","Mindfulness","Postmenopausal Symptoms",[67,68,69,70,71],"mindfulness","postmenopausal","depression","sleep quality","anxiety","2026-02-14",{"date":74,"type":39},"2026-02-20",{"date":76,"type":21},"2026-03-01",{"date":41,"type":21},{"name":45,"class":46},{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":55,"sex":16,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":96,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":104,"completionDateStruct":105,"leadSponsor":107,"locationsCount":4},"100625637","acute-effects-of-kinesiology-taping-on-performance-in-volleyball-players-100625637","NCT07425223","Acute Effects of Kinesiology Taping on Performance in Volleyball Players","Acute Effects of Kinesiology Taping on Functional Performance in Volleyball Players: A Randomized, Sham-Controlled Trial","Inclusion Criteria:\n\n* Being between 13-19 years of age.\n* Being within the full range of active glenohumeral elevation.\n* Both the participant and the parent must be volunteers.\n* Being a licensed volleyball player for at least one year. - Participants must be female.\n* Having previously undergone kinesiological taping and not having developed sensitivity.\n\nExclusion Criteria:\n\n* Participant's unwillingness to participate in the study\n* Having an acute or active injury to the shoulder complex within the last 6 months\n* Individuals with a history of sensitivity to kinesiological tape\n* Presence of a severe cardiopulmonary, orthopedic, or neurological disease\n* Presence of physical discomforts such as severe dizziness","13 Years","19 Years",{"count":89,"type":21},24,[24],"Kinesiological tape is frequently used to provide support for injured muscles and joints, enhance fascial function, inhibit pain-inducing stimuli, and improve blood and lymph circulation. However, there is no consensus among researchers and practitioners regarding kinesiological taping, particularly its application to improve athletic performance. This study aimed to investigate the acute changes in functional performance of volleyball players who underwent kinesiological taping. Designed as a randomized controlled experimental study, it planned to include 24 licensed female volleyball players from Anadolu Marmara Sports Schools. Players meeting the inclusion criteria were randomized into kinesiological tape (n:12) and sham (dummy-ineffective) tape (n:12) groups. The assessment will consist of a general warm-up program followed by the single-arm hop test for upper extremity strength, speed, and stability; the closed kinetic chain upper extremity endurance test for strength and endurance; and the medicine ball throw test for functional strength. Following the initial assessment, tests will be repeated immediately after facilitative taping of the pectoralis major and anterior deltoid muscles of the athletes. SPSS 24 statistical program will be used for data analysis. Continuous variables will be presented as mean ± standard deviation, and qualitative variables as number and percentage (%). If the assumptions for parametric tests are met, the Independent Samples t-test will be used for comparing independent groups, and the Paired Samples t-test will be used for comparing dependent groups. If the assumptions for parametric tests are not met, the Mann-Whitney U test will be used for comparing independent groups, and the Wilcoxon test will be used for comparing dependent groups. Statistical significance will be accepted at p≤0.05. This study is expected to contribute to performance-enhancing practices in volleyball players by providing evidence-based data on the application method and effectiveness of kinesiological taping for functional performance.",[93,94,95],"Volleyball","Kinesiology Taping","Functional Performance",[97,98,99,100,101],"volleyball","kinesiology taping","performance","endurance","speed","2026-02-13",{"date":74,"type":39},{"date":74,"type":21},{"date":106,"type":21},"2026-04-20",{"name":45,"class":46},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":55,"sex":115,"minAge":116,"maxAge":17,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":118,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":4},"100625357","acute-effects-of-kinesiology-taping-on-performance-in-soccer-players-100625357","NCT07421583","Acute Effects of Kinesiology Taping on Performance in Soccer Players","Acute Effects of Kinesiology Taping on Functional Performance in Soccer Players: A Randomized, Sham-Controlled Trial","Inclusion Criteria:\n\n* The participant must be a volunteer and have agreed to participate with a consent form.\n* The participant must be between 14-18 years of age.\n* The participant must have been a licensed soccer player for at least one year.\n\nExclusion Criteria:\n\n* The participant must not wish to participate in the study.\n* The participant must have a history of lower extremity injury in the last 12 months.\n* The participant must have a severe cardiopulmonary, orthopedic, or neurological disease.\n* The participant must have physical discomforts such as severe dizziness.\n* The participant must have reported sensitivity to kinesiological tape.","MALE","14 Years",{"count":89,"type":21},[24],"Kinesiological taping, frequently used today for the prevention and rehabilitation of musculoskeletal injuries and to support athlete performance, has become a popular technique in the field of sports science. However, scientific evidence on the short-term effects of this application on athletes is limited. In this context, the aim of this study is to evaluate the acute changes in functional performance parameters such as speed, agility, and explosive power in football players who underwent kinesiological taping.\n\nThe aim of this study is to examine the acute effects of kinesiological taping on agility, speed, and lower extremity explosive power in football players. Participants aged 14-18 years who meet the inclusion criteria will be randomized into kinesiological tape (n:12) and sham tape (n:12) groups using a closed envelope method. The T-Agility Test will be used for agility, the 30 m Sprint Test for speed, and the Standing Long Jump Test for lower extremity explosive power. All participants will perform agility, speed, and explosive power tests after the same warm-up program. Following the initial assessment, participants will undergo quadriceps muscle technique using kinesiological taping and sham taping by the same physiotherapist. Tests will be repeated immediately after the tapes are applied. The findings are expected to provide information on the potential of kinesiological taping to contribute to short-term performance improvement in soccer players and its effects on preventing sports injuries.",[121,94,95],"Soccer",[123,98,99,124],"soccer player","taping","2026-02-12",{"date":127,"type":39},"2026-02-19",{"date":129,"type":21},"2026-02-01",{"date":131,"type":21},"2026-03-25",{"name":45,"class":46},{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":140,"minAge":141,"maxAge":17,"enrollmentInfo":142,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":145,"conditions":146,"keywords":150,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":4},"100623269","respiratory-function-respiratory-muscle-strength-and-hand-function-in-hemiparetic-cerebral-palsy-100623269","NCT07394439","Respiratory Function, Respiratory Muscle Strength, and Hand Function in Hemiparetic Cerebral Palsy","Association of Respiratory Function and Respiratory Muscle Strength With Hand Function in Children With Hemiparetic Cerebral Palsy","Inclusion Criteria:\n\n* Confirmed diagnosis of hemiparetic cerebral palsy by a physician.\n* Sufficient cognitive ability to understand and follow test instructions, as judged by a parent or clinician.\n* Clinically stable condition for at least 3 months, with no changes in medication, acute exacerbations, or modifications in rehabilitation programs.\n* Physical capacity sufficient to tolerate pulmonary function testing (spirometry), maximum inspiratory\u002Fexpiratory pressure (MIP\u002FMEP) measurements, and other study assessments.\n\nExclusion Criteria:\n\n* Current or recent acute respiratory infection, asthma exacerbation, pneumonia, or known cardiopulmonary disease that may affect testing.\n* Receipt of intensive upper extremity interventions other than routine physiotherapy (e.g., botulinum toxin injections, surgical procedures) within the past 6 months.\n* History of major orthopedic surgery (e.g., hip reconstruction, scoliosis surgery) within the past 3 months.\n* Severe musculoskeletal contracture or deformity that prevents the safe performance of pulmonary function testing.\n* Severe epilepsy, uncontrolled seizures, or other neurological conditions that may compromise safety during testing.","ALL","6 Years",{"count":143,"type":21},37,"OBSERVATIONAL","The goal of this observational study is to learn how respiratory function and respiratory muscle strength are related to hand use in children and teenagers with hemiparetic cerebral palsy (CP) aged 6 to 18 years.\n\nThe main questions it aims to answer are:\n\nIs respiratory function related to hand function in children with hemiparetic CP? Is respiratory muscle strength related to hand function in children with hemiparetic CP? Is respiratory function related to how strong children can squeeze with their affected hand? Is respiratory muscle strength related to how strong children can squeeze with their affected hand? Is respiratory function related to how well children use their hands in daily activities? Is respiratory muscle strength related to how well children use their hands in daily activities? Is respiratory function related to children's hand skill level? Is respiratory muscle strength related to children's hand skill level?\n\nParticipants will:\n\nVisit the clinic one time for a single assessment session. Do simple lung tests using a small portable device to measure respiratory function.\n\nDo tests that measure how strong their breathing muscles are.\n\nComplete hand and arm tests, including:\n\nA hand grip strength test, A simple block-moving test, A short questionnaire about using the hand in daily life, A standard hand skill rating. Researchers will look at how respiratory measures are related to hand strength, hand skills, and daily hand use. This study may help improve rehabilitation programs by showing whether respiratory muscle strength and hand skills should be trained together in children with hemiparetic CP.",[147,148,149],"Cerebral Palsy","Respiratory Function Tests","Fine Motor Skills",[151,152,153,154],"Hemiparetic Cerebral Palsy","Respiratory Function","Respiratory Muscle Strength","Hand Function","2026-02-03",{"date":157,"type":39},"2026-02-06",{"date":159,"type":21},"2026-01-23",{"date":161,"type":21},"2026-03-09",{"name":45,"class":46},{"id":164,"slug":165,"hasResults":11,"nctId":166,"briefTitle":167,"officialTitle":168,"acronym":4,"eligibilityCriteria":169,"healthyVolunteers":11,"sex":16,"minAge":170,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":173,"briefSummary":174,"conditions":175,"keywords":178,"overallStatus":181,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":47},"100616327","investigation-of-the-effectiveness-of-a-exergame-program-in-women-with-fibromyalgia-100616327","NCT07304167","Investigation of the Effectiveness of a Exergame Program in Women With Fibromyalgia","Investigation of the Effectiveness of a Video-Based Exercise (Exergame) Program in Women With Fibromyalgia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Women aged between 30 and 70 years, which is an age range in which fibromyalgia (FM) is more prevalent;\n* Having a diagnosis of fibromyalgia;\n* Being willing to participate in the study and signing the informed consent form;\n* Meeting the 2016 American College of Rheumatology (ACR) diagnostic criteria, defined as a Widespread Pain Index (WPI) ≥ 7 and a Symptom Severity Scale (SSS) score ≥ 5, or WPI = 4-6 and SSS ≥ 9.\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Any known advanced pathology related to the locomotor system that contraindicates physical activity (such as arthritis, osteoarthritis, or uric acid disorders)\n* Epilepsy\n* History of severe headache\n* Neurological disorder\n* Peripheral neuropathy\n* Known severe cardiovascular disease (such as endocranial hypertension, uncontrolled arterial hypertension, heart failure, or presence of a pacemaker)\n* Orthopedic disorders of the upper or lower extremities that prevent participation in physical activity\n* Rheumatologic disease other than fibromyalgia\n* Pneumothorax\n* Neoplasia\n* Surgery within the last four months\n* Severe psychiatric illness (such as uncontrolled depression and anxiety, personality disorders, dementia, or cognitive impairments related to substance abuse)\n* Diagnosis of alcohol dependence or use of psychoactive drugs or narcotics\n* Participation in any physical activity program within two months prior to the start of the study\n* Body mass index (BMI) greater than 29.9","30 Years","70 Years",{"count":59,"type":21},[24],"The goal of this clinical trial is to compare the effects of an exergame-based exercise program and a home-based exercise program in women aged 30-70 years diagnosed with fibromyalgia (FM).\n\nThe main questions it aims to answer are:\n\nDoes an exergame-based program using the Nintendo Switch game Ring Fit Adventure improve pain, balance, and functional mobility in women with fibromyalgia? Is the exergame program more effective than a traditional home-based exercise program in improving physical and psychosocial outcomes? Researchers will compare the exergame group and the home-based exercise group to determine whether game-based exercises provide superior benefits in pain reduction, balance, and quality of life.\n\nParticipants will:\n\nBe randomly assigned to either the exergame or the home-based exercise group. Exercise twice a week for four weeks under the supervision of a physiotherapist or via remote monitoring.\n\nUndergo evaluations before and after the 4-week training period, and again after a 4-week detraining period.\n\nAssessments will include:\n\nPain intensity (Visual Analog Scale) Disease severity (Revised Fibromyalgia Impact Questionnaire, Widespread Pain Index, Symptom Severity Scale, Fibromyalgia Severity Scale) Lower extremity strength (Sit-to-Stand Test) Functional mobility (Timed Up and Go Test) Balance (Single-Leg Stance Test, Berg Balance Scale) Psychosocial status (Cognitive Exercise Therapy Approach Questionnaire - BETY-BQ) Quality of life (Short Form-12) Study findings are expected to provide evidence for the effectiveness of exergame applications as an enjoyable rehabilitation approach for individuals with fibromyalgia.",[176,177],"Fibromyalgia","Exergaming",[176,177,179,180],"Exercise","Rehabilitation","RECRUITING","2026-01-08",{"date":184,"type":39},"2026-01-09",{"date":186,"type":39},"2025-12-15",{"date":188,"type":21},"2026-03-05",{"name":45,"class":46},{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":11,"sex":140,"minAge":17,"maxAge":57,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":198,"briefSummary":199,"conditions":200,"keywords":208,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":222},"100606658","muscle-architecture-vs-alfredson-protocol-in-achilles-tendinopathy-100606658","NCT07178418","Muscle Architecture vs Alfredson Protocol in Achilles Tendinopathy","The Effects of a Muscle Architecture-Based Exercise Program and the Alfredson Protocol on Muscle-Tendon Architecture and Physical Performance in Subjects With Achilles Tendinopathy","Inclusion Criteria:\n\n* Presence of pain and tenderness in the mid-portion of the Achilles tendon (2-6 cm proximal to the insertion) persisting for at least 3 months\n* Clinical diagnosis of non-insertional Achilles tendinopathy\n* Pain aggravated by physical activity\n* Palpable tenderness localized to the mid-portion of the tendon\n* Voluntary participation in the study with signed informed consent\n\nExclusion Criteria:\n\n* Diagnosis of insertional Achilles tendinopathy\n* History of surgery or fracture in the affected lower limb within the past 12 months\n* Corticosteroid injection to the Achilles tendon within the past month\n* Presence of systemic diseases (e.g., diabetes mellitus, rheumatoid arthritis)\n* Presence of neurological disorders (e.g., peripheral neuropathy, central nervous system disorders)\n* Prior experience with eccentric exercise protocols targeting the Achilles tendon\n* Acute onset of symptoms suggestive of a tendon rupture",{"count":59,"type":21},[24],"Achilles tendinopathy is a frequent overuse disorder caused by repetitive loading of the tendon, particularly observed in athletes and middle-aged men. It is typically characterized by mid-portion pain, stiffness in the morning, and functional limitations, with structural alterations such as thickening and disrupted collagen alignment. Chronic progression often compromises performance and quality of life.\n\nEccentric training protocols, such as the Alfredson regimen, are commonly prescribed but their standardized nature does not fully address individual variability. Alternative approaches including Heavy Slow Resistance training and progressive loading models (e.g., Silbernagel protocol) have demonstrated clinical effectiveness and higher patient adherence, yet they still apply uniform loading across the triceps surae without accounting for architectural differences.\n\nGiven the heterogeneous structure of the soleus and gastrocnemii, targeted loading strategies may be required to optimize tendon adaptation. To address this, the present study employs a muscle architecture-based exercise program tailored to the functional and structural properties of each muscle. Ultrasound imaging will be used to evaluate muscle-tendon morphology, while isokinetic dynamometry and functional performance tests will quantify outcomes. Pain (VAS) and functional capacity (VISA-A) will also be assessed.\n\nThis randomized controlled trial aims to compare the effectiveness of an architecture-specific program with the Alfredson protocol on tendon remodeling, strength, endurance, functional performance, and symptom reduction in individuals with non-insertional Achilles tendinopathy.",[201,202,203,204,205,206,207],"Achilles Tendinopathy (AT)","Eccentric Exercise Training","Muscle Architecture","Isokinetic Test","Ultrasound","Balance","Anaerobic Power",[209,210,211,212,213],"Achilles tendinopathy","muscle architecture","isokinetic strength","Alfredson protocol","tendon architecture","2025-09-10",{"date":216,"type":39},"2025-09-17",{"date":218,"type":21},"2025-10-15",{"date":220,"type":21},"2026-12-31",{"name":45,"class":46},2,{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":140,"minAge":17,"maxAge":4,"enrollmentInfo":230,"targetDuration":4,"studyType":22,"phases":232,"briefSummary":233,"conditions":234,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":245,"leadSponsor":247,"locationsCount":4},"100604118","virtual-reality-intervention-for-symptom-management-in-stem-cell-transplantation-100604118","NCT07145359","Virtual Reality Intervention for Symptom Management in Stem Cell Transplantation","Development and Evaluation of A Virtual Reality Intervention for Symptoms Management During Hematopoietic Stem Cell Transplantation","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Able to speak and understand Turkish\n* Scheduled to undergo allogeneic hematopoietic stem cell transplantation (HSCT)\n* Receiving stem cell products collected from peripheral blood\n* Voluntarily agree to participate in the study and provide informed consent\n\nExclusion Criteria:\n\n* Undergoing autologous hematopoietic stem cell transplantation\n* Receiving stem cell products collected from bone marrow\n* Diagnosed with medical or psychiatric comorbidities that could interfere with participation, as reported by the healthcare team\n* Presenting infection symptoms (e.g., respiratory, gastrointestinal) that may contaminate study equipment, as identified by the healthcare team\n* Having visual, auditory, verbal, or cognitive impairments that may prevent interaction with the VR equipment\n* Previously received any form of hematopoietic stem cell transplantation",{"count":231,"type":21},30,[24],"The goal of this clinical trial is to evaluate whether a virtual reality (VR) intervention based on the Symptom Management Model can reduce physical and psychosocial symptoms during hematopoietic stem cell transplantation (HSCT) in adult patients undergoing allogeneic transplantation.\n\nThe main questions it aims to answer are:\n\nDoes the VR intervention reduce distress levels during HSCT?\n\nDoes the VR intervention decrease state anxiety and symptom severity compared to standard care?\n\nDoes the VR intervention positively affect physiological outcomes and engraftment times?\n\nResearchers will compare a group receiving standard clinical care plus a VR nature-themed video during HSCT to a group receiving standard care only to see if the VR intervention improves symptom management outcomes.\n\nParticipants will:\n\nBe randomly assigned to either the intervention or control group.\n\nIn the intervention group:\n\nWatch a 15-minute nature-themed VR video during stem cell infusion using Meta Quest 3.\n\nThe video content will be specifically created by the research team based on the principles of Attention Restoration Theory (ART).\n\nIn both groups:\n\nComplete pre- and post-intervention assessments including:\n\nDistress Thermometer\n\nState-Trait Anxiety Inventory\n\nEdmonton Symptom Assessment Scale\n\nPhysiological measures (vital signs)\n\nEngraftment tracking\n\nSatisfaction and open-ended feedback forms",[235,236,237,238,239,240],"Cancer and \u002F or Hematological Malignancy","Hematopoetic Stem Cell Transplantation","Nursing Interventions","Symptom Management","Virtual Reality","ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION","2025-08-21",{"date":243,"type":39},"2025-08-28",{"date":214,"type":21},{"date":246,"type":21},"2026-09-10",{"name":45,"class":46},{"id":249,"slug":250,"hasResults":11,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":55,"sex":16,"minAge":255,"maxAge":256,"enrollmentInfo":257,"targetDuration":259,"studyType":144,"phases":4,"briefSummary":260,"conditions":261,"keywords":263,"overallStatus":181,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":222},"100603174","body-awareness-upper-extremity-function-and-quality-of-life-in-breast-cancer-survivors-100603174","NCT07133087","Body Awareness, Upper Extremity Function, and Quality of Life in Breast Cancer Survivors","Body Awareness, Upper Extremity Function, and Quality of Life in Breast Cancer Survivors: A Case-Control Study","Inclusion Criteria for breast cancer survivors:\n\n* Being a woman\n* Being between the ages of 25 and 75\n* Having been diagnosed with Stage 0-III breast cancer\n* Having completed primary treatments (surgery, chemotherapy, and\u002For radiation therapy) no more than 6 months prior to the assessment date\n* Having received medical clearance from a physician\n* Having undergone either breast-conserving surgery or mastectomy due to breast cancer\n* Willingness to participate in the study voluntarily\n\nExclusion Criteria for breast cancer survivors:\n\n* Having a history of rehabilitation due to upper extremity, thoracic, or cervical musculoskeletal disorders within 6 months prior to the breast cancer diagnosis\n* Having a history of neuromuscular dysfunction\n* Using medications that may affect neuromuscular performance\n\nInclusion criteria for the control group:\n\n* Being a woman\n* Having a body mass index (BMI) within ±3 kg\u002Fm² of the breast cancer survivor group\n* Being within ±5 years of age compared to the breast cancer survivor group\n* Matching hand dominance with the breast cancer survivor group\n\nExclusion criteria for the control group:\n\n* Having a history of neuromuscular dysfunction\n* Using medications that may affect neuromuscular performance\n* Having a history of rehabilitation due to upper extremity, thoracic, or cervical musculoskeletal disorders within the last 6 months","25 Years","75 Years",{"count":258,"type":21},42,"1 Day","Breast cancer is one of the most common types of cancer among women and one of the leading causes of morbidity and mortality. With increasing survival rates, issues such as treatment-related morbidities and consequently upper extremity dysfunction, reduced body awareness, and decreased quality of life are frequently encountered. In the literature, the impact of treatment-related morbidities-particularly on upper extremity functions, body awareness, and quality of life-among women who have survived breast cancer treatment has not been sufficiently investigated. This gap constitutes a significant shortcoming in terms of clinical practices and the post-treatment period.\n\nThis study aims to examine the effects of breast cancer treatment on upper extremity functions, body awareness, and quality of life in women who have survived breast cancer treatment, in comparison with a healthy control group. The study will be conducted at Yeditepe University Koşuyolu Hospital between May, 2025, and October, 2025. Participants will include women who have survived breast cancer treatment and a healthy control group matched based on criteria such as age and body mass index.\n\nIn the study, three separate assessments will be conducted for upper extremity functions: the \"Quick Disabilities of the Arm, Shoulder, and Hand\" (QuickDASH) questionnaire for upper extremity functionality, a hand dynamometer for grip strength, and the Clinometer device for shoulder joint position sense. The \"Body Awareness Questionnaire\" will be used to assess body awareness, and the \"EORTC QLQ-C30\" scale will be used for quality of life assessment. The IBM SPSS Statistics software package will be used for data analysis. In statistical analyses, a significance level of p\\\u003C0.05 will be considered.",[262],"Breast Cancer Female",[264,265],"breast cancer","body awareness","2025-08-13",{"date":268,"type":39},"2025-08-20",{"date":270,"type":39},"2025-05-06",{"date":272,"type":21},"2025-11-15",{"name":45,"class":46},{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":4,"eligibilityCriteria":280,"healthyVolunteers":11,"sex":140,"minAge":17,"maxAge":18,"enrollmentInfo":281,"targetDuration":4,"studyType":22,"phases":283,"briefSummary":284,"conditions":285,"keywords":287,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":294,"lastUpdatePostDateStruct":295,"startDateStruct":297,"completionDateStruct":299,"leadSponsor":300,"locationsCount":47},"100545832","effects-of-balance-exercises-performed-with-different-visual-stimuli-100545832","NCT06387043","Effects of Balance Exercises Performed With Different Visual Stimuli","Comparison of the Effects of Balance Exercises Performed With Different Visual Stimuli in Individuals With Multiple Sclerosis","Inclusion Criteria:\n\n* ages of 18-50\n* diagnosis of MS by a neurologist according to McDonald 2017 criteria (Carroll, 2018)\n* Being between 2.5 and 4.5 on the Expanded Disability Status Scale (EDSS)\n* Not having had an attack in the last 3 months\n* Absence of spasticity severe enough to affect treatment (spasticity in any joint of the upper extremity and lower extremity is \\\u003C2 according to the Modified Ashworth Scale)\n* Getting ≥ 24 points from the Standardized Mini Mental Test (SMMT)\n\nExclusion Criteria:\n\n* hearing or vision problems\n* pregnancy\n* Having changed medication in the last 3 months and using medication containing the active ingredient Fampridine\n* Participating or participating in a regular physiotherapy and rehabilitation program in the last 3 months\n* other accompanying neurological, orthopedic or vestibular disorders\n* an upper or lower extremity contracture that prevents exercises\n* History of epileptic seizure, migraine or vertigo attack in the last 6 months",{"count":282,"type":21},40,[24],"The study aims to examine the effects of balance exercises applied with different visual stimuli on individuals with MS.",[286],"Multiple Sclerosis",[288,289,290,291,292,293],"multiple sclerosis","visual stimulus","balance","virtual reality","stroboscopic glasses","metaphoric imaginary","2024-04-24",{"date":296,"type":39},"2024-04-26",{"date":298,"type":21},"2024-12-01",{"date":43,"type":21},{"name":45,"class":46},""]