[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Harokopio University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":165},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,63,85,116,143],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":62},"100608351","meliora-virtual-coach-intervention-for-breast-cancer-prevention-100608351",false,"NCT07200427","MELIORA Virtual Coach Intervention for Breast Cancer Prevention","Multimodal Engagement and Sustainable Lifestyle Interventions Optimizing Breast Cancer Risk Reduction Supported by Artificial Intelligence","MELIORA","Inclusion Criteria:\n\nMELIORA-HEALTHY study participants must meet all of the following criteria in order to be deemed eligible for study participation:\n\n* Reside in Greece, Lithuania, or Spain.\n* Be female and at least 18 years of age.\n* Have access to and be able to use a smartphone (iOS or Android) compatible with the MELIORA app.\n* Be willing and able to use the MELIORA app for the entire study duration.\n* Willing to provide informed consent to participate in the study.\n* Have at least one of the following behavioural or metabolic risk factors for BC, assessed in a random order (each site may determine the order that is most convenient for them) until eligibility is confirmed. If a risk factor is identified, the subsequent assessments can be skipped:\n* Increased alcohol consumption: More than 1 drink per day.\n* Increased body mass index (BMI): BMI ≥ 25 kg\u002Fm² or waist circumference ≥80 cm for normal weight individuals.\n* Physical inactivity: Not meeting World Health Organization (WHO) guidelines of at least 150 minutes of moderate-intensity or 75 minutes of high-intensity aerobic exercise per week during the last month.\n* Suboptimal diet: Low diet quality based on the rapid Prime Diet Quality Score Screener (rPDQS).\n\nMELIORA-PATIENTS study participants must meet all of the following criteria in order to be deemed eligible for study participation:\n\n* Reside in Spain or Lithuania.\n* Be female and at least 18 years old.\n* Have access to and be able to use a smartphone (iOS or Android) compatible with the MELIORA app.\n* Be willing and able to use the MELIORA app for the entire study duration.\n* Willing to provide informed consent to participate in the study.\n* Have been diagnosed with breast cancer (BC) within the last 6 months and\u002For currently undergoing treatment (chemotherapy, radiotherapy, immunotherapy, hormone therapy) and\u002For in active follow-up.\n* Have at least one of the following behavioural or metabolic risk factors for BC, assessed in a random order (each site may determine the order that is most convenient for them) until eligibility is confirmed. If a risk factor is identified, the subsequent assessments can be skipped:\n* Increased alcohol consumption: More than 1 drink per day.\n* Increased body mass index (BMI): BMI ≥ 25 kg\u002Fm² or waist circumference ≥80 cm for normal weight individuals.\n* Physical inactivity: Not meeting World Health Organization (WHO) guidelines of at least 150 minutes of moderate-intensity or 75 minutes of high-intensity aerobic exercise per week during the last month.\n* Suboptimal diet: Low diet quality based on the rapid Prime Diet Quality Score Screener (rPDQS).\n\nMELIORA-SURVIVORS study participants must meet all of the following criteria in order to be deemed eligible for study participation:\n\n* Reside in Spain, Lithuania, or Sweden.\n* Be female and at least 18 years old.\n* Have access to and be able to use a smartphone (iOS or Android) compatible with the MELIORA app.\n* Be willing and able to use the MELIORA app for the entire study duration.\n* Willing to provide informed consent to participate in the study.\n* Have completed primary treatment for breast cancer (surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, etc.) and currently be in remission.\n* Be considered \"cancer-free\" according to their treating physician and may enter the study immediately following this diagnosis.\n* Ongoing adjuvant hormone therapy is permitted.\n* Have at least one of the following behavioural or metabolic risk factors for BC, assessed in a random order (each site may determine the order that is most convenient for them) until eligibility is confirmed. If a risk factor is identified, the subsequent assessments can be skipped:\n* Increased alcohol consumption: More than 1 drink per day.\n* Increased body mass index (BMI): BMI ≥ 25 kg\u002Fm² or waist circumference ≥80 cm for normal weight individuals.\n* Physical inactivity: Not meeting World Health Organization (WHO) guidelines of at least 150 minutes of moderate-intensity or 75 minutes of high-intensity aerobic exercise per week during the past month.\n* Suboptimal diet: Low diet quality based on the rapid Prime Diet Quality Score Screener (rPDQS).\n\nExclusion Criteria:\n\nMELIORA-HEALTHY study participants will be excluded from study participation if they meet any of the following criteria:\n\n* Inability to provide fully informed consent.\n* Inability to understand or communicate in the local language i.e. Greek in Greece, Lithuanian in Lithuania, Spanish in Spain.\n* Current or past diagnosis of cancer or other uncontrolled chronic diseases (e.g., cardiovascular disease, diabetes) that affect lifestyle, dietary habits, or communication skills.\n* Mental illness or disorders that affect lifestyle, dietary habits, or communication skills.\n* Use of medication that affects lifestyle, dietary habits, or communication skills.\n* Recreational drug use.\n* Pregnancy, lactation, or intention to become pregnant shortly before, during, or after the intervention.\n* Participation in another clinical trial or program aimed at promoting behavioural changes or weight loss at the time of recruitment. If subjects already use health-related apps that affect their weight and lifestyle, including dietary habits and physical activity, the research team will ask them to pause their use until the end of the 12-month study period. However, the use of these applications by the participants cannot be controlled.\n\nMELIORA PATIENTS and MELIORA SURVIVORS study participants will be excluded from study participation if they meet any of the following criteria:\n\n* Inability to provide fully informed consent.\n* Inability to understand or communicate in the local language (i.e., Lithuanian in Lithuania, Spanish in Spain, Swedish in Sweden), unless appropriate translation support is available to ensure full understanding of study procedures and informed consent.\n* Current or past diagnosis of cancer (other than breast cancer, except skin cancer treated with surgery only) or other uncontrolled chronic diseases (e.g., cardiovascular diseases, diabetes) that affect lifestyle, dietary habits, or communication skills.\n* Mental illness or disorders that affect lifestyle, dietary habits, and communication skills.\n* Use of medication that affects lifestyle, dietary habits, or communication skills.\n* Recreational drug use.\n* Pregnancy, lactation, or intention to become pregnant shortly before, during, or after the intervention.\n* Participation in another clinical trial or program to promote behavioural changes or weight loss during recruitment. Suppose participants are already using health-related apps affecting their weight and lifestyle, including dietary habits and physical activity. In that case, they will be asked to suspend their use until the end of the 12-month study period. However, the research team cannot control the use of these applications by the participants.\n* Severe adherence issues with previous treatments that may interfere with compliance with study tasks (subject to the investigator's assessment).",true,"FEMALE","18 Years",{"count":21,"type":22},2080,"ESTIMATED","INTERVENTIONAL",[25],"NA","Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors. Traditional prevention strategies have shown limited effectiveness, creating the need for innovative approaches. The MELIORA project develops an AI-driven digital tool, the Virtual Coach (VC), to promote sustainable behaviour change in physical activity, diet, and alcohol use. Three randomized-controlled studies will be conducted: MELIORA-HEALTHY (women at risk, n=1080 in Greece, Lithuania, Spain), MELIORA-PATIENTS (women undergoing treatment, n=400 in Lithuania, Spain), and MELIORA-SURVIVORS (post-treatment survivors, n=600 in Lithuania, Spain, Sweden). Participants across diverse regions and backgrounds will be randomized to standard lifestyle advice or the same advice plus the MELIORA VC app. Each study lasts 12 months, with outcomes assessed at baseline, 6, and 12 months. The primary outcome is physical activity, with secondary outcomes including sedentary behaviour, diet, alcohol use, and quality of life. If effective, the MELIORA VC could offer a scalable, cost-effective model for BC prevention and survivorship care, providing valuable evidence to guide public health strategies.",[28],"Breast Cancer Prevention",[30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49],"Behavior change","Disease prevention","Health behaviour","Primary prevention","Public and environmental health","Breast cancer","Cancer prevention","Sustainable intervention","Nutrition","Diet","Physical activity","Exercise","Lifestyle","Public health","Cancer risk factors","Health communication","Digital health","Health technologies","Artificial intelligence","randomized controlled trial","RECRUITING","2026-06-12",{"date":53,"type":54},"2026-06-15","ACTUAL",{"date":56,"type":54},"2026-03-01",{"date":58,"type":22},"2027-09",{"name":60,"class":61},"Harokopio University","OTHER",7,{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":23,"phases":73,"briefSummary":74,"conditions":75,"keywords":76,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":84,"locationsCount":62},"100607554","meliora-data-collection-campaigns-100607554","NCT07190066","MELIORA Data Collection Campaigns","Data Collection Campaigns for Early Development Versions of the MELIORA Digital Tools","DCC","Inclusion Criteria:\n\n* Individuals residing in Greece, Lithuania, Spain or Sweden.\n* Female adults (i.e. ≥18 years of age).\n* Ability to understand and complete the outcome measures in one of the participating countries' local languages.\n* Ability to provide fully informed consent.\n* Having access to and being able to use a smartphone that supports the project app (i.e., iOS or Android smartphone)\n* Meeting the criteria for allocation to one of the three following groups:\n\n  * Healthy women with a calculated Βody Μass Ιndex (BMI) ≥ 25 or not meeting the World Health Organization's recommendations of ≥150 minutes of moderate-to-vigorous physical activity per week.\n  * Women currently undergoing active treatment for breast cancer or awaiting to begin active treatment for breast cancer.\n\n    * Women survivors of BC having completed active treatment at least six months prior to study enrolment\n\nExclusion Criteria:\n\n* Inability to provide fully informed consent.\n* Inability to understand and communicate in one of the recruitment countries' local languages.",{"count":72,"type":22},300,[25],"To support the development of the MELIORA digital app for the MELIORA main intervention, an initial pilot study (Data Collection Campaign, DCC) is being conducted with the three target participant groups: healthy women at increased risk of developing breast cancer (BC), BC patients, and BC survivors across the four intervention countries (Spain, Greece, Lithuania, Sweden). The planned sample size for each group is 156 healthy women at risk (defined as not meeting recommendations for a healthy lifestyle), 58 BC patients, and 86 BC survivors. Each participant is asked to test and evaluate a preliminary version of the MELIORA app over a 14-day period. The DCC takes place in the early stages of the project, as part of the intervention development phase, to inform the technical refinement and preliminary evaluation of the MELIORA digital app.",[28],[77,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49],"Behaviors change","2025-09-25",{"date":80,"type":54},"2025-09-30",{"date":82,"type":54},"2025-04-22",{"date":80,"type":22},{"name":60,"class":61},{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":93,"minAge":94,"maxAge":95,"enrollmentInfo":96,"targetDuration":4,"studyType":23,"phases":98,"briefSummary":99,"conditions":100,"keywords":102,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},"100586016","a-study-of-chios-mastic-water-in-dyspepsia-100586016","NCT06909890","A Study of Chios Mastic Water in Dyspepsia","The Effectiveness of a Natural Aqueous Extract of Chios Mastic in the Management of Dyspepsia: the MASTIQUA-D Randomized Controlled Clinical Trial","MASTIQUA-D","Inclusion Criteria:\n\n* Age 30-60 years old.\n* Body mass index of 20-35 kg\u002Fm2.\n* Presence of dyspepsia.\n\nExclusion Criteria:\n\n* Presence of chronic diseases (e.g. diabetes mellitus, cancer, cardiovascular, hepatic, renal, respiratory, chronic inflammatory and psychiatric diseases).\n* Presence of other chronic gastrointestinal diseases (e.g. gastroesophageal reflux, inflammatory bowel disease and celiac disease).\n* Use of immunosuppressants, anti-inflammatories, antibiotics and corticosteroids.\n* Use of dietary supplements or other products with Chios mastic.\n* Excessive alcohol consumption (\\>210 g and \\>140 g of ethanol per week for men and women, respectively).\n* Currently on a weight-loss diet or recent (within 6 months) significant change in lifestyle habits.\n* Pregnancy or breast feeding (for women)","ALL","30 Years","60 Years",{"count":97,"type":22},60,[25],"Chios mastic is a natural product with strong antimicrobial, anti-inflammatory and antioxidant properties, and well-established benefits for dyspeptic disorders. The aim of the present study is to investigate the effectiveness of a natural aqueous extract of Chios mastic (mastic water), a by-product of Chios mastic processing, in the management of dyspepsia. This will be a 3-month randomized double-blind controlled clinical trial in adults with dyspepsia. Participants will be blindly randomized to an intervention group, which will receive 600 mL\u002Fd of a carbonated beverage enriched with Chios mastic water (0.2%), or a control group, which will receive 600 mL\u002Fd of an identical placebo beverage with no active ingredients. Participants will be evaluated in terms of anthropometric indices, lifestyle habits, severity of dyspepsia-related gastrointestinal symptoms, quality of life, as well as biochemical markers, both pre- and post-intervention.",[101],"Dyspepsia",[103,104,105,106],"Pistacia Lentiscus var. Chia","Chios mastic","dyspepsia","gastrointestinal health","2025-09-09",{"date":109,"type":54},"2025-09-15",{"date":111,"type":54},"2025-07-10",{"date":113,"type":22},"2026-12",{"name":60,"class":61},1,{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":120,"acronym":121,"eligibilityCriteria":122,"healthyVolunteers":17,"sex":93,"minAge":19,"maxAge":123,"enrollmentInfo":124,"targetDuration":4,"studyType":23,"phases":126,"briefSummary":127,"conditions":128,"keywords":130,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":142,"locationsCount":62},"100602230","better4all-personalized-intervention-pilot-study-100602230","NCT07120802","Better4All Personalized Intervention Pilot Study","BETTER4ALL","Inclusion Criteria:\n\n* Age: Participants aged 18-65 years to represent the adult general population.\n* Body Mass Index (BMI):\n\n  * Overweight or obesity group: BMI ≥ 25 kg\u002Fm².\n  * Normal weight group: BMI 18.5-24.9 kg\u002Fm².\n* Technology Use:\n\n  * Willingness and ability to use wearable devices and an Android mobile application for the duration of the study.\n  * Owning a smartphone device with the Android operating system.\n* Eating utensil technique: dominant hand gestures that correspond to handling of food via a fork or a spoon.\n* Language Proficiency: Ability to read and understand the language in which the mobile app and study materials are provided.\n* Consent: Willing to provide informed consent to participate in the study.\n* Residency: Must be a resident of one of the seven participating countries.\n* Availability: Able to participate for the full three-week duration of the study and comply with the study protocol.\n\nExclusion Criteria:\n\n* Health Conditions: Pregnant or breastfeeding women, as they might have different lifestyle behaviours or health needs.\n* Physical Limitations: Any physical or mental condition that would prevent the participant from using the wearable device or mobile application as intended.\n* Eating utensil technique: eating food with chopsticks on a daily or regular basis.\n* Technical Incompatibility: Individuals who do not own a compatible smartphone or are unable to use the provided wearable devices for technical reasons.","65 Years",{"count":125,"type":22},490,[25],"The BETTER4U project (Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you) is funded by the European Union (EU) and involves an international consortium consisting of 28 partners across Europe, Israel, and Australia. The project started in November 2023 and will run until October 2027. The main aim of BETTER4U is to improve weight management through a tailor-made intervention, the \"BETTER4ALL personalized intervention\", using modern monitoring tools and artificial intelligence (AI), including machine learning (ML) practices.\n\nIn the context of the BETTER4U project, the present Pilot Study aims to a) evaluate the usability, feasibility and acceptability of the BETTER4U mobile application (\"BETTER4U App\") and Intervention Platform that will be used to monitor and collect data from participants in the BETTER4ALL personalized intervention (randomized controlled trial; RCT) and b) collect data to evaluate and improve the BETTER4U causal AI models for the prevention of weight gain, before deploying them at large scale, as well as test and identify the optimal ways of delivering the AI-based interventions to the participants. The study will be conducted in seven sites in Cyprus, France, Greece, Poland, Portugal, Spain, and Sweden.\n\nThe BETTER4All Pilot Study will be a longitudinal, correlational, observational study, including a total of n=490 participants, equally distributed among the seven sites (i.e. n=70 per site). Specifically, n=60 (± 3-5) \"general population\" participants (henceforth: \"end-users\" of the wearables and the BETTER4U App) and n=10 (± 3-5) healthcare or other types of providers (henceforth: potential \"implementers\" of the BETTER4U intervention) will constitute each site's sample.\n\nThe study will involve the following two components: a) the administration of the wearables (smartwatches) to the \"end-users\" and their registration to and training on the BETTER4U App, to be used for a total duration of three weeks (21 days). During this period, their lifestyle behaviours (i.e. \"BETTER4U Core Behavioural Indicators - BCBIs\", such as eating occasions, physical activity, sedentary time, sleep etc.) and \"living environment indicators - LEIs\"; (e.g. access to parks in your area, distance from your home to your work place etc.) will be recorded daily, either in an automated way via the wearables or self-reported by the end-users through the App; and b) the registration to and training on the BETTER4U Intervention Platform of the \"implementers\" for a total duration of one week (7 days), during which they will be asked to test the platform's functionalities using synthetic data. The implementers will also be provided with the wearables and the App (similarly to the end-users) for one week only to allow collection of additional data that will help verify the accuracy of the algorithms in the gathered data from the wearables\u002Fmonitoring tools regarding BCBIs and LEIs.\n\nOverall, the outcomes and the findings of the Pilot Study will be used to further refine, optimize, and adjust the tools for the BETTER4ALL RCT, according to the feedback received by both end-users' and implementers' perspectives.",[129],"Obesity Prevention",[131,132,133,134,135,49],"weight management","polygenic risk score","artificial intelligence","personalized intervention","obesity","2025-08-06",{"date":138,"type":54},"2025-08-13",{"date":140,"type":54},"2025-06-01",{"date":80,"type":22},{"name":60,"class":61},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":147,"acronym":121,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":93,"minAge":19,"maxAge":123,"enrollmentInfo":149,"targetDuration":4,"studyType":23,"phases":151,"briefSummary":152,"conditions":153,"keywords":154,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":62},"100592751","better4all-personalized-intervention-100592751","NCT06997510","Better4All Personalized Intervention","Inclusion Criteria:\n\n* Age: Participant aged 18-65 years\n* Body Mass Index (BMI): BMI ≥ 25 kg\u002Fm² (overweight or obesity)\n* Willingness and ability to use wearable devices and an Android mobile application for the duration of the study\n* Owning a smartphone device with Android operating system\n* Eating utensil technique: dominant hand gestures that correspond to handling of food via a fork or a spoon\n* Language proficiency: participant has the ability to read and understand the language in which the mobile app and study materials are provided\n* Consent: participant is willing to provide informed consent to participate in the study\n* Residency: participant is resident of the country\n* Availability: participant is able to participate for the full three-week duration of the study and comply with the study protocol\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding or intending to get pregnant in the short-term\n* Comorbidities which might affect inflammation levels (i.e. type 1 diabetes, uncontrolled type 2 diabetes, unstable cardiovascular disease, eating disorders, gastrointestinal disorders)\n* Mental illness affecting cognitive and communication skills, lifestyle and\u002For dietary habits\n* History of cancer within 5 years prior to intervention onset\n* Physical Limitations: any physical or mental condition that would prevent the participant from using the wearable device or mobile application as intended\n* Any other criterion which would deem the participant unsuitable, according to the investigator's impression\n* Technical Incompatibility: Individual does not own a compatible smartphone or are unable to use the provided wearable devices for technical reasons\n* Documented and\u002For self-reported rapid changes in body weight in the six months preceding intervention onset, attributed to a diagnosed medical condition\n* Interventional drug treatment in a clinical trial in the period within six months prior to intervention onset, which might affect intervention impact\n* Inability to adhere to the proposed diet regimens, due to medical (i.e. gluten intolerance, allergies, swallowing problems) or religious reasons\n* Medication promoting weight loss\n* Bariatric surgery in the 12 months preceding intervention onset\n* Use of supplements promoting weight loss or sleep quality, mood enhancing supplements, and\u002For consumption of probiotics and medications that influence the microbiome in the last three months preceding intervention onset Participation in a different clinical trial protocol or participation in different programs aiming at weight loss during the six months preceding intervention onset",{"count":150,"type":22},1022,[25],"The BETTER4U (Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you) project, funded by the European Union, aims to address obesity through biologically and behaviourally tailored interventions. Obesity is a major public health issue influenced by genetic, metabolic, and lifestyle factors. Despite current weight management interventions, many individuals face challenges due to these varied influences. The BETTER4U project seeks to improve weight management by incorporating artificial intelligence (AI) and polygenic risk scores (PRS) to personalize interventions. The goal is to test the effectiveness of these personalized interventions in improving weight loss compared to standard care, using advanced monitoring tools and AI models.\n\nThe BETTER4ALL personalized intervention is a multicentre, open-label, parallel-group randomized controlled trial (RCT) involving seven study sites across Cyprus, France, Greece, Poland, Portugal, Spain, and Sweden. A total of 1,022 participants with overweight or obesity (BMI ≥ 25 kg\u002Fm²), aged 18-65 years, will be enrolled. Participants will be randomized into two groups: an intervention group receiving personalized lifestyle recommendations based on AI and PRS, and a control group receiving standard care recommendations. The intervention will last six months, followed by a six-month follow-up assessment.\n\nThe intervention's key aspects include wearable devices and a mobile application to monitor participants' behaviour, including physical activity, sleep, and eating habits. The intervention also integrates genetic, metabolic, and environmental data to provide tailored recommendations for weight loss. Participants' outcomes will be assessed regarding BMI, weight loss maintenance, changes in clinical biomarkers, body composition, and other lifestyle parameters.\n\nThis RCT will provide valuable insights into the effectiveness of personalized weight management strategies. AI-driven personalized recommendations and real-time monitoring represent a significant shift from traditional, one-size-fits-all approaches. The results of this study could offer a more effective and sustainable model for obesity management, particularly by accounting for individual genetic predispositions and lifestyle factors. Furthermore, by evaluating the impact of the intervention on a wide range of health outcomes, including biomarkers and psychosocial factors, the study will provide a comprehensive understanding of how personalized interventions can improve overall health and weight management.\n\nIn addition to contributing to the scientific understanding of obesity and its management, this project has the potential to influence public health strategies, offering a more personalized, data-driven approach to obesity prevention and treatment. By integrating genetic, environmental, and lifestyle factors, the BETTER4U intervention could pave the way for future innovations in digital health and obesity management.",[129],[131,132,155,134,135,49],"aritificial intelligence","NOT_YET_RECRUITING","2025-05-21",{"date":159,"type":54},"2025-05-30",{"date":161,"type":22},"2025-10-01",{"date":163,"type":22},"2027-04-01",{"name":60,"class":61},""]