[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Harrison Shong-Wen Chow\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100633952","extended-emergence-strategy-on-post-anesthesia-care-unit-events-after-outpatient-orthopedic-surgery-100633952",false,"NCT07533370","Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery","Extended Emergence Trajectory on Post-Anesthesia Care Units Events in Ambulatory Lower-Extremity Orthopedic Surgery: A Randomized Controlled Trial","PACU-EMERGE","Inclusion Criteria:\n\n* Participants with American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for Elective Foot\u002FAnkle Orthopaedic surgery at Stanford Health under planned propofol-based intravenous anesthesia and regional nerve block for preoperative analgesia\n* Able and willing to complete all cognitive assessments and Brice Interview in PACU\n\nExclusion Criteria:\n\n* ASA physical status IV or V\n* Chronic opioid therapy\n* Chronic benzodiazepine use or ongoing treatment with strongly anticholinergic medications within 30 days prior to surgery.\n* Known major neuro-cognitive disorder, active psychotic disorder, or other severe psychiatric condition that, in the opinion of the investigator, would interfere with valid cognitive testing.\n* Active cardiac or neurological stimulators or pumps in use\n* Severe uncorrected visual or hearing impairment that precludes valid cognitive battery or interview completion.\n* Inability to speak and understand the study language sufficiently to provide informed consent and complete study assessments.\n* Inability to provide informed consent or lack of a legally authorized representative when required.\n* Concurrent participation in another interventional study that could confound PACU cognitive or delirium outcomes.",true,"ALL","18 Years",{"count":21,"type":22},300,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks. The primary questions it aims to answer are:\n\n* Does a longer wake-up help participants think more clearly soon after surgery compared with usual approaches?\n* Does it lower pain scores, lower the amount of pain medications used, and shorten the time it takes to go home from recovery room?\n\nResearchers will compare 2 groups of adults who are having similar lower-extremity orthopaedic surgeries with regional and propofol anesthesia.",[28,29,30],"Perioperative Care","EEG Power Spectra","Delirium - Postoperative",[32,33,34,35],"Post-anesthesia care unit (PACU)","Postoperative delirium","EEG-guided anesthesia","Neurocognitive outcomes","NOT_YET_RECRUITING","2026-05-19",{"date":39,"type":40},"2026-05-22","ACTUAL",{"date":42,"type":22},"2026-07",{"date":44,"type":22},"2027-10",{"name":46,"class":47},"Harrison Shong-Wen Chow","OTHER",""]