[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Haute Ecole ARC Sante\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":87},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100584783","influence-of-the-culture-care-program-on-patient-mobility-after-thoracic-or-abdominal-surgery-a-mixed-methods-study-100584783",false,"NCT06893848","Influence of the Culture Care Program on Patient Mobility After Thoracic or Abdominal Surgery: a Mixed-methods Study","Culture Care Program: a Mixed-methods Study Evaluating the Effect of an Innovative In-hospital Experience on Patient Mobility After Thoracic or Abdominal Surgery","CULTURECARE","Inclusion Criteria:\n\n* Admission to Surgical Units in the Surgical Department of the Hôpital de Neuchâtel implementing the Culture Care program.\n* Elective thoracic or abdominal surgery with an expected hospital stay of at least 2 days (i.e. discharge on postoperative day 3).\n* Neurocognitive and physical ability to complete questionnaires and individual participation in the Culture Care program.\n* Full capacity of discernment and signed informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Outpatient surgery.\n* Emergency surgery.\n* Mobility severely impaired prior to surgery: patients with 1 or 2 lower-limb amputations, patients with wheelchair mobility only, neurodegenerative diseases.\n* Bed restiction between POD 1 and POD 5 for medical reasons, i.e. surgery, post-operative complications or other pre-existing cardiorespiratory, neurological or orthopedic reasons.\n* Transfer to ICU\n* Only during the Culture Care phase, an unplanned transfer to another unit that does not have the Culture Care program (e.g. Medicine units).\n* Technical problem with the accelerometer (e.g. disfunctioning battery).\n* Allergic reaction to any dressing used to attach the accelerometer.\n* End-of-life patients.",true,"ALL","18 Years",{"count":21,"type":22},204,"ESTIMATED","INTERVENTIONAL",[25],"NA","A sedentary behavior in the postoperative phase has a negative impact on recovery from various types of surgery (e.g. abdominal, pulmonary, cardiac or esophageal). In fact, sedentary behavior in the days following surgery is associated with an increased risk of postoperative complications, longer hospital stays and, consequently, higher healthcare costs. Stimulating early mobilization and increasing the level of physical activity after surgery therefore remains a relevant current challenge. The Culture Care program will propose a new experience of the hospital towards an attractive and stimulating intrahospital environment, including art and culture. The hypothesis is that the innovative, positive hospital experience offered by the Culture Care program could contribute to increasing patients' mobility in the postoperative phase and thus reduce the sedentary behaviour compared with a control group included before the implementation of the program.\n\nThe aim of this study is to explore the effect of the Culture Care program (Control group versus Culture Care group) on the mobility of patients hospitalized after thoracic or abdominal surgery, by determining the level of prediction in relation to the influencing covariates reported in the literature.\n\nThe first quantitative part of this research project will compare the mobility of patients hospitalized after surgery, before (control group) and after the implementation of the Culture Care program (Culture Care group). Patients will be asked to wear an accelerometer for the first five post-operative days, and to complete three questionnaires (psychological well-being, physical recovery, perception of their mobility).\n\nHealthcare workers will be asked to complete a survey on their readiness to stimulate patients' mobility before and after the Culture Care program.\n\nThe second part will be qualitative including individual semi-structured interviews with patients and healthcare workers during the Culture Care program, to gather their experiences.",[28,29,30,31],"Thoracic Surgery","Abdominal Surgery Patients","Hospital Mobility","Mobility Limitation",[33,34,35,36],"Physical activity","Postoperative recovery","Accelerometer","Early mobilization","RECRUITING","2026-06-23",{"date":40,"type":41},"2026-06-24","ACTUAL",{"date":43,"type":41},"2025-03-10",{"date":45,"type":22},"2027-12",{"name":47,"class":48},"Haute Ecole ARC Sante","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},"100604137","effects-of-early-rehabilitation-using-blood-flow-restriction-andor-surface-electromyography-biofeedback-on-quadriceps-activation-and-strength-after-anterior-cruciate-ligament-reconstruction-a-multicenter-randomized-controlled-trial-100604137","NCT07145606","Effects of Early Rehabilitation Using Blood Flow Restriction and\u002For Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18-35 years.\n\nFirst-time anterior cruciate ligament (ACL) reconstruction.\n\nPre-injury activity level Tegner ≥ 6.\n\nMarx activity scale ≥ 12.\n\nBody mass index \\\u003C 35.\n\nWith or without associated meniscal injury.\n\nExclusion Criteria:\n\n* Revision ACL surgery.\n\nConcurrent repair of other knee ligaments.\n\nNeurological or systemic musculoskeletal disorders.\n\nContraindications to blood flow restriction (BFR) or surface EMG monitoring\u002Fbiofeedback.\n\nPregnancy or lactation.\n\nLanguage barrier or cognitive impairment preventing valid informed consent; vulnerable populations not enrolled.","35 Years",{"count":58,"type":22},200,[25],"Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury. Two rehabilitation strategies-low-load blood flow restriction (BFR) training and surface electromyography (sEMG) biofeedback-aim to enhance neuromuscular activation and strength while limiting joint load. However, comparative and combined evidence in pragmatic, multicenter settings remains limited.\n\nAMIRACL is a multicenter, prospective, randomized, controlled, parallel-group trial with four arms enrolling 200 adults (18-35 years) undergoing a first-time ACL reconstruction. Participants are randomized with center stratification; outcome assessors are blinded to allocation. The four groups are: (1) standard rehabilitation; (2) standard + early BFR; (3) standard + early sEMG biofeedback; and (4) standard + combined BFR and sEMG biofeedback. Interventions begin about 2 weeks postoperatively, are delivered over 6 weeks at three supervised sessions per week, and are integrated into contemporary ACL rehabilitation. BFR uses individualized, auto-regulated cuff pressure during low-load isometric and then dynamic exercises. sEMG biofeedback provides real-time visual and\u002For auditory feedback to optimize quadriceps recruitment during targeted tasks. The combined arm receives both modalities concurrently.\n\nThe primary objective is to compare quadriceps activation (sEMG) and maximal isometric knee extensor strength between groups at 3 and 6 months. Secondary objectives include return-to-sport readiness and patient-reported function (e.g., ACL-RSI, IKDC), broader knee outcomes (e.g., KOOS, Lysholm), adherence and adverse events across arms, and ACL re-injury (ipsilateral graft rupture or contralateral ACL injury) within 2 years. Longer-term patient-reported quality of life is explored up to 5 years.\n\nKey eligibility criteria include age 18-35 years, first ACL reconstruction, and preinjury sport participation; major exclusions include revision ACL surgery, concomitant multi-ligament repair, neuromuscular disorders, and contraindications to BFR or sEMG. The planned sample size is 200 (50 per arm), powered to detect a clinically meaningful between-group difference in quadriceps activation. Analyses will follow the intention-to-treat principle using mixed-effects models for repeated measures. The study is conducted under Good Clinical Practice and applicable Swiss regulations; all participants provide written informed consent. Overall, AMIRACL will determine whether early BFR, sEMG biofeedback, or their combination meaningfully improves quadriceps activation, strength, and clinical recovery after ACL reconstruction compared with standard rehabilitation alone.",[62,63,64],"Anterior Cruciate Ligament Injuries","Knee Injuries","Muscle Weakness",[66,67,63,68,69,70,71,72,73,74,75,76],"Anterior Cruciate Ligament","ACL Reconstruction","Rehabilitation","Quadriceps Muscle","Quadriceps Activation","Muscle Strength","Arthrogenic Muscle Inhibition","Blood Flow Restriction Training","Surface Electromyography","Biofeedback","Return to Sport","NOT_YET_RECRUITING","2025-08-21",{"date":80,"type":41},"2025-08-28",{"date":82,"type":22},"2026-01-02",{"date":84,"type":22},"2031-01-02",{"name":47,"class":48},4,""]