[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hellenic Mediterranean University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":124},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,75,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100631071","effect-of-glp-1-receptor-agonists-on-body-composition-in-obesity-the-role-of-dietary-protein-consumption-in-muscle-mass-maintenance-100631071",false,"NCT07495904","Effect of GLP-1 Receptor Agonists on Body Composition in Obesity: The Role of Dietary Protein Consumption in Muscle Mass Maintenance","The Effect of GLP-1 Receptor Agonist-based Treatment on Body Composition and Muscle Mass in Adults With Obesity: The Role of Dietary Protein Consumption in Muscle Mass Maintenance","LEAN-PRO GLP-1","Inclusion Criteria:\n\n* Adults 30-65 years old\n* BMI: ≥30 kg\u002Fm²\n* Signed Informed Consent\n\nExclusion Criteria:\n\nA. Metabolic and Medical Conditions:\n\n* Uncontrolled type 2 diabetes (HbA1c \\> 9.0%)\n* Known cardiovascular disease (e.g., coronary artery disease, heart failure NYHA 3-4)\n* Chronic kidney disease stage 4-5 (GFR \\\u003C60 ml\u002Fmin)\n* Liver disease (known hepatitis, ALT ≥ 3 or total bilirubin ≥ 2 times ULN)\n* Inflammatory bowel disease\n* Celiac disease\n* History of pancreatitis\n* Any disorder potentially causing malabsorption\n* Active cancer or history of malignancy within the past 3 years\n* Psychiatric disorders affecting adherence or assessment B. Medication and Supplement Use\n* Chronic use of medications affecting metabolism or body composition (e.g., corticosteroids, anti-obesity drugs)\n* Use of anti-inflammatory or antioxidant medications\n* Use of probiotics, prebiotics, or laxatives within the last month\n* Unstable medication regimen (changes within the past 3 months)\n* Use of protein and creatine supplements.\n\nC. Dietary and Lifestyle Factors:\n\n* Alcohol or substance abuse\n* Engagement in intense regular physical activity\n\nD. Reproductive Status:\n\n* Pregnancy or breastfeeding\n* Pregnancy within the past 12 months\n* Plans to become pregnant during the study\n\nE. Other:\n\n\\- Any condition that, in the opinion of the Investigator, may interfere with participation, adherence, or the interpretation of study results.","ALL","30 Years","65 Years",{"count":21,"type":22},130,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study investigates how weight-loss medications, specifically GLP-1 receptor agonists, affect body composition, with a special focus on preserving muscle mass in adults with obesity. While these medications are highly effective for weight loss, they can sometimes lead to an unwanted loss of valuable muscle mass (a condition that can lead to sarcopenia).\n\nTo explore how to prevent this, researchers are conducting a 3- to 6-month randomized controlled trial involving adults aged 30 to 65 years with a BMI greater than 30 kg\u002Fm². Participants who are receiving GLP-1 medications will be randomly assigned to one of two groups: one group will receive the standard medication treatment alone, while the other group will receive the medication along with specific dietary guidance focused on increasing daily protein intake.",[28],"Obesity",[30,31,32,33,34],"Body composition","pharmacologically induced weight loss","GLP-1 receptor agonists","muscle mass","dietary protein","RECRUITING","2026-03-28",{"date":38,"type":39},"2026-04-02","ACTUAL",{"date":41,"type":22},"2026-03-30",{"date":43,"type":22},"2029-01-30",{"name":45,"class":46},"Hellenic Mediterranean University","OTHER",2,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":47},"100557996","nurse-led-education-on-patients-with-chronic-heart-failure-and-their-informal-caregivers-100557996","NCT06545370","Nurse-led Education on Patients With Chronic Heart Failure and Their Informal Caregivers","The Impact of Nurse-led Education on Patients With Chronic Heart Failure and Their Informal Caregivers in Optimizing the Care for Both and Improving the Clinical Outcomes of Patients","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients recently hospitalized due to the disease\n* Patients and caregivers who are literate in Greek\n* Patients and caregivers who provide written informed consent for their participation in the study\n* Patients diagnosed with heart failure for at least 6 months\n* Caregivers who have been involved in the care of the patients for at least 6 months\n* Patients taking medication according to the guidelines of the European Society of Cardiology\n\nExclusion Criteria:\n\n* History of psychiatric disease, recent history of alcohol or\u002Fand drug abuse, dementia, and Alzheimer\\'s disease (for patients and caregivers)\n* Absence of an informal caregiver according to their statement","18 Years",{"count":57,"type":22},280,[25],"The current study intends to examine the influence of nurse-led education on patients with chronic heart failure and their caregivers, with the goal of optimizing care for both and improving patients\\' clinical outcomes.",[61],"Heart Failure",[63,64,65,66],"Heart failure","informal caregivers","patient outcomes","nurse-led education","2025-09-19",{"date":69,"type":39},"2025-09-24",{"date":71,"type":39},"2024-09-01",{"date":73,"type":22},"2027-09-01",{"name":45,"class":46},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":4},"100606234","nutrition-education-by-nurses-in-patients-after-coronary-artery-bypass-grafting-effect-on-patients-dietary-pattern-adherence-and-clinical-outcomes-100606234","NCT07172906","\"Nutrition Education by Nurses in Patients After Coronary Artery Bypass Grafting: Effect on Patients' Dietary Pattern, Adherence and Clinical Outcomes\"","Inclusion Criteria:\n\n* Age over 18 years\n* Patients who underwent CABG and were discharged from the hospital in the previous 10 days\n* Knowledge of reading and writing in Greek by the patients\n* Provision of written informed consent by the patients for their participation in the study\n\nExclusion Criteria:\n\n* History of psychiatric illness, recent history of alcohol and\u002For drug abuse, dementia or Alzheimer's disease\n* Patients with comorbidities (diabetes mellitus, chronic renal failure, idiopathic inflammatory bowel disease, other gastrointestinal disorders, food allergies, etc.) that would justify the adoption of a special dietary pattern that is not identical to the proposed dietary pattern\n* Patients with a preference for strict vegetarianism (vegan) and\u002For cultural-religious beliefs that do not allow the adoption of the proposed dietary pattern",{"count":82,"type":22},160,[25],"The purpose of this study is the investigation of the effect of nurse-led nutritional education of post-CABG patients on their dietary pattern, on their adherence to it, but also on their quality of life and well-being.",[86],"Coronary Heart Disease",[88,89,90,91],"Coronary Artery Bypass Grafting","Nutritional Education from nurses","Weight measurement","adherence to the Mediterranean diet","NOT_YET_RECRUITING","2025-09-08",{"date":95,"type":39},"2025-09-15",{"date":97,"type":22},"2025-10",{"date":99,"type":22},"2027-10",{"name":45,"class":46},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":23,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},"100561176","effect-of-nurse-led-education-and-tele-interventions-on-reducing-surgical-site-infections-in-patients-after-coronary-artery-bypass-surgery-a-clinical-trial-100561176","NCT06586749","Effect of Nurse-Led Education and Tele-Interventions on Reducing Surgical Site Infections in Patients After Coronary Artery Bypass Surgery: a Clinical Trial","The Effect of Patient Education and Implementation of Teleinterventions by Nurses, on the Incidence of Surgical Wound Infections, in Patients After Coronary Artery Bypass Surgery","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients who have undergone CABG with median sternotomy\n* Proficiency in reading and writing in Greek\n* Patients who provide written informed consent for participation in the study\n* Patients who have access to a mobile phone and know how to use it\n* Patients without difficulties in vision, speech, or hearing\n* Patients at intermediate or high risk for developing surgical site infections, based on their scores in the risk stratification models described below\n\nExclusion Criteria:\n\n* History of psychiatric illness, recent history of alcohol and\u002For substance abuse, dementia, and Alzheimer's disease\n* Presence of an active infection within 2 weeks prior to the surgical procedure\n* Preoperative hospitalization \\> 2 days\n* Concurrent surgery on the aorta or heart valves\n* Urgent or emergency nature of the surgical procedure\n* Re-sternotomy aimed at surgical re-exploration of bleeding or implementation of cardiopulmonary resuscitation (CPR) in cases of cardiac arrest\n* Patients in whom the sternum has not been closed after the completion of the surgical procedure and who are transferred to the cardiothoracic unit without sternum closure\n* Active endocarditis\n* Life expectancy \\\u003C 6 months\n* Lack of a smartphone",{"count":109,"type":22},220,[25],"The goal of this clinical trial is to determine if nurse-led education and tele-interventions can reduce the incidence of surgical wound infections in patients after coronary artery bypass surgery. The main questions it aims to answer are:\n\n* Can nurse-led education reduce the rate of surgical wound infections after coronary artery bypass surgery?\n* Does the addition of tele-interventions further decrease the incidence of these infections compared to standard care?\n\nResearchers will compare three groups:\n\n* Group A: Standard postoperative care\n* Group B: Nurse-led patient education\n* Group C: Nurse-led patient education plus tele-interventions\n\nParticipants will:\n\n* Receive standard care, nurse-led education, or nurse-led education with tele-interventions\n* Having regular follow-up as per group assignment\n* Monitor and report infection during the study period",[113,114],"Surgical Site Infection","Coronary Artery Bypass Grafting (CABG)","2024-09-04",{"date":117,"type":39},"2024-09-19",{"date":119,"type":39},"2024-03-01",{"date":121,"type":22},"2025-09-01",{"name":45,"class":46},1,""]