[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Helse Møre og Romsdal HF\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":243},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,50,82,118,145,166,192,216],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100594578","dbt-skill-training-for-autistic-adults-with-difficulties-in-emotion-regulation-100594578",false,"NCT07021274","DBT Skill Training for Autistic Adults With Difficulties in Emotion Regulation.","DBT Skill Training for Autistic Adults With Difficulties in Emotion Regulation: a Feasibility Study.","Inclusion Criteria:\n\n* Fit general inclusion criteria for the out- patient treatment at the clinic.\n* Have diagnosed autism, and pervasive difficulties in emotion regulation.\n* Speak Scandinavian (Norwegian, Danish and\u002For Swedish).\n* Manage to commit to participating in the DBT- skills training.\n* Be willing to sign the written informed consent.\n\nExclusion Criteria:\n\n* Have a clinically significant low linguistic functioning that hinders the patient in understanding and answering the questions on the self-report instruments.\n* Being actively psychotic.\n* Have a Body Mass Index (BMI) under 17.\n* Cognitive disability Intelliganve quotient (IQ) \\\u003C85","ALL","18 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23],"NA","One in 44 has autism, 70% of them have additional mental health challenges. Currently, this patient population does not have access to effective treatment within specialist healthcare services and has struggled to benefit from standard treatments. The goal of this project is to increase access to treatment tailored to their challenges. We will investigate whether a treatment program with an adapted version of Dialectical Behavior Therapy (DBT) is feasible, accepted, and perceived as useful for people with autism. The purpose of the treatment is to improve emotion regulation, function better in relationships, and avoid crises, thereby enhancing their ability to achieve personal goals, reduce suffering, and increase quality of life. Autism is a lifelong neurodevelopmental disorder, presenting with great variation and more widespread than previously thought. Difficulties with emotion regulation are a central challenge for many with autism. These difficulties often manifest as an inability to recognize, understand, and manage emotional responses, leading to destructive strategies, behaviors, and suffering. DBT is developed with a focus on emotion regulation and has shown good effects in other patient populations. The project can increase access to treatment for a patient population that currently stands without.",[26,27,28],"Difficulties of Emotion Regulation","Self-harm Behavior","Autism Spectrum Disorder",[30,31,32,33,34,35,36],"Autisim","emotion regulation","DBT skills training","adults","ASD","Feasibility","Autism spectrum disorder","RECRUITING","2026-06-26",{"date":40,"type":41},"2026-06-29","ACTUAL",{"date":43,"type":41},"2025-08-15",{"date":45,"type":20},"2027-02-28",{"name":47,"class":48},"Helse Møre og Romsdal HF","OTHER_GOV",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":21,"phases":61,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":49},"100638168","genicular-nerve-block-in-knee-arthroplasty-100638168","NCT07589127","GENicular Nerve Block in KNEE Arthroplasty","GENicular Nerve Block in KNEE Arthroplasty - The GENKNEE Trial","GENKNEE","Inclusion Criteria:\n\n* Symptomatic knee OA grade II-IV according to the Kellgren-Lawrence classification system scheduled for primary total knee arthroplasty\n* American Society of Anesthesiologists (ASA) Physical Status grade I-III\n* Able to provide written informed consent\n* Able to undergo surgery under spinal anesthesia\n\nExclusion Criteria:\n\n* Younger than 18 or older than 80 years\n* ASA physical status IV\n* Allergy to local anesthetics\n* Revision surgery\n* Chronic opioid use (\\> 3 months)\n* Coagulopathy\n* Cognitive impairment\n* Inability to comply with study procedures\n* Patients scheduled for day care surgery.","80 Years",{"count":60,"type":20},70,[23],"The goal of this clinical trial is to learn whether a preoperative genicular nerve block (GNB) can reduce pain after knee replacement surgery in adults with knee osteoarthritis (OA) undergoing total knee arthroplasty (TKA). It will also assess whether this treatment can reduce opioid use and improve recovery.\n\nThe main questions it aims to answer are:\n\n* Does a preoperative GNB reduce pain during movement 24 hours after surgery compared with placebo?\n* Does it reduce opioid consumption and improve physical activity and functional outcomes after surgery?\n\nResearchers will compare patients receiving a GNB to patients receiving a placebo injection to see if the nerve block improves postoperative pain and recovery.\n\nParticipants will:\n\n* Be randomly assigned to receive either a GNB or a placebo injection before surgery\n* Undergo standard knee replacement surgery and postoperative care\n* Report pain levels at regular intervals after surgery\n* Complete questionnaires on function, quality of life, and recovery\n* Wear an activity monitor to measure physical activity after surgery\n* Attend follow-up assessments at 1 week, 1 month, and 3 months",[64,65,66],"Osteoarthritis (OA) of the Knee","Total Knee Arthroplasty","Genicular Nerve Block",[68,69,70,71,72],"Osteoarthritis","Knee","Knee osteoarthritis","Total knee arthroplasty","Genicular nerve block","NOT_YET_RECRUITING","2026-05-11",{"date":76,"type":41},"2026-05-15",{"date":78,"type":20},"2026-06-01",{"date":80,"type":20},"2029-06-01",{"name":47,"class":48},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":94,"studyType":95,"phases":4,"briefSummary":96,"conditions":97,"keywords":104,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},"100622297","modern-technologies-in-lower-respiratory-tract-infections-in-children-100622297","NCT07381790","Modern Technologies in Lower Respiratory Tract Infections in Children","Modern Technologies for Individual Risk Stratification in Infant Lower Respiratory Tract Infections","MoT-LRTI","Inclusion Criteria:\n\n* clinical diagnosis of lower respiratory tract infection\n* with tachypnea and\u002For\n* wheezing\n* Retractions\n* Respiratory difficulties\n\nExclusion Criteria:\n\n* Severe Congenital heart disease (not ASD, small VSD, PDA)\n* Cystic fibrosis and PCD\n* Neuromuscular diseases and other diseases with reduced airway clearance\n* Severe malacia, diagnosed by bronchoscopy by time of T0.\n* Foreign body inhalation\n* Pneumothorax\n* Pleural effusion (with need of invasive interventions)\n* Bronchopulmonary dysplasia or GA \\\u003C32 weeks\n* Caretaker not able to communicate in Norwegian or English\n* Weight \\\u003C3 kg","0 Days","24 Months",{"count":93,"type":20},200,"1 Year","OBSERVATIONAL","Lower respiratory tract infections (LRTIs) are a significant cause of childhood morbidity and mortality globally, particularly in low-income countries. In Norway, LRTIs is a leading cause of hospitalization among infants, representing a great socioeconomic burden.\n\nBronchiolitis, a viral infection, is the main representation of LRTIs in infants. It affects the small airways, causing breathing- and feeding difficulties. Today, treatment relies on subjective evaluations, lacking objective measures for assessment. This increases the risk of both under- and over treating patients. In the long term, bronchiolitis increases risk of asthma, but it is unknown who the high-risk patients for chronic lung disease are.\n\nLung ultrasonography (LUS) has emerged as a promising tool for assessing bronchiolitis severity and progression of the disease. The investigators will explore its use to improve diagnostic accuracy and treatment decisions, and develop AI-driven scoring tools for novel technology.\n\nAdditionally, tidal breathing flow volume loops (TBFVL) offer a non-invasive method for evaluating airway obstruction in infants, with the potential to assess severity of bronchiolitis, treatment efficacy and post-infection lung function.\n\nIn this project the investigators will combine the use of these modern technologies to improve treatment and follow-up of infants with LRTIs.\n\nThe main aim for this observational study is to assess the utility of lung ultrasonography (LUS) and tidal flow volume loops (TBFVL) in infant lower respiratory tract infections (LRTIs) for individual risk stratification in acute and chronic settings. This aims to refine the management of bronchiolitis, identifying high-risk patients for chronic lung disease to tailor treatment and follow-up protocols.\n\nThe project has three secondary objectives.\n\n1. To assess correlation between LUS and TBFVL findings with clinical score at admission, length of stay, need of respiratory support and ICU admissions.\n2. To assess duration of symptoms following acute bronchiolitis and evaluate the use of LUS and TBFVL in objectively examine post-infectious sequela.\n3. To evaluate the long-term impact of bronchiolitis on lung function through clinical follow-up after a 12 month period.\n\nLower respiratory tract infections (LRTIs) stand as the leading cause of hospitalization, while asthma is the leading cause of chronic lung disease among children in Nordic countries. The project seeks to improve risk stratification and treatment protocols in both acute and chronic settings.\n\nIn the acute setting, the project endeavors to prognosticate individual patient outcomes, thereby individualize treatment and mitigating unnecessary hospital admissions, use of respiratory support and antibiotic administration. Additionally there is potential of more aggressive treatment to selected patients. The study aims to improve the understanding of pathophysiological processes of LRTIs in infants, providing objective metrics to evaluate disease severity and individualize treatment.\n\nThe investigators aim to validate the utility, validity, and simplicity of handheld ultrasound devices as bedside diagnostic tools for this common disease, alongside affirming the value of tidal flow volume loops (TBFVL) in acute and chronic settings to assess airway obstruction in infants. Combining these modern technologies, evaluating affliction of both the parenchyme and the airways will probide a new perspective in treatment of LRTIs. In addition the project will strive to develop novel technology with AI-driven scoring tools of LUS.\n\nFurthermore, the project aims to examine the trajectory of symptoms post-LRTI and facilitate the early identification of patients with high-risk of chronic lung disease. Early detection of asthma and other chronic lung diseases holds the potential to improve outcomes and mitigate the need for hospitalization, thus easing both economic and emotional burdens associated with the disease.\n\nFor caregivers, the lack of information concerning symptom duration and risk of future disease represents a significant knowledge gap. The project aims to address this, by examining post-infection symptom duration and identifying high-risk cohorts predisposed to chronic lung disease. This has the potential to both improve information, personalize follow-up and reduce hospital readmissions.",[98,99,100,101,102,103],"Bronchiolitis Acute","Lower Respiratory Tract and Lung Infections","Pediatric Lung Ultrasound","Tidal Volume","Pediatric Lung Diagnosis","Pediatric Asthma",[105,106,107,108],"pediatric","lung ultrasound","lower respiratory tract infections","tidal-flow volume loops","2026-01-26",{"date":111,"type":41},"2026-02-02",{"date":113,"type":41},"2025-12-15",{"date":115,"type":20},"2029-06-30",{"name":47,"class":48},2,{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":124,"eligibilityCriteria":125,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":126,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":128,"conditions":129,"keywords":131,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":49},"100431466","intravenous-antibiotic-treatment-at-home-100431466","NCT04898452","Intravenous Antibiotic Treatment at Home","Intravenous Antibiotic Treatment at Home: A New Model for Across Services Interaction With the Use of Welfare Technology and Telemedicine.","Hosp@Home","Inclusion criteria:\n\n* Main or bi-diagnosis during stay:\n\nA692 Borreliosis G00 - G009 Central nervous system inflammatory disorders I33 Endocarditis J86 Empyema D46.3 Spondylodiscitis M86 Osteomyelitis T84 Prosthesis \u002F osteosynthesis infections M00.0-M00.9 Pyogen \u002F septic arthritis J40-J47 Chronic diseases of the lower respiratory tract\n\n* Competent to give consent\n* The infection can not be treated with oral antibiotics in monotherapy\n* Selected IV antibiotics must be suitable for administration via selected pumps\n* The patient's condition is stable and does not require frequent observation by health care professionals\n* The patient is motivated and willing to participate in intravenous treatment in home hospitals\n* Must, after training, demonstrate mastery of practical procedures related to pump handling and any other procedures described in the patient's treatment plan\n* The home must be suitable for intravenous antibiotic treatment; access to refrigerators, hygienic conditions, social conditions\n* The patient must have a mobile phone and be able to handle the system for fast and secure communication with the Regional Response Center (RRO)\n\nExclusion criteria:\n\n* consent not given",{"count":127,"type":20},50,"The purpose of the study is to develop and evaluate a new model for across services interaction with the use of welfare technology and telemedicine. The model includes innovative and new routines for the exchange of patient information, quality systems and procedures between the municipality and the hospital. This model will first be tested for use in intravenous antibiotic therapy. The results of the study will be used to further develop the service. In the larger context, it is desirable to provide knowledge that is transferable to other diagnostic groups, treatment methods and geographical areas.",[130],"Infection",[132,133,134,135,136],"Home Care Services, Hospital-Based","Telemedicine","Home Infusion Therapy","Hospital at home","Antibiotics","2025-06-17",{"date":139,"type":41},"2025-06-22",{"date":141,"type":41},"2020-07-02",{"date":143,"type":20},"2026-12-31",{"name":47,"class":48},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":58,"enrollmentInfo":152,"targetDuration":4,"studyType":21,"phases":154,"briefSummary":155,"conditions":156,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":49},"100555050","the-personalknee-trial-100555050","NCT06507046","The personalKNEE Trial","Robotic Assisted Surgery Comparing Personalized Alignment Versus Mechanical Alignment of Total Knee Arthroplasty - A Randomized Controlled Trial","Inclusion Criteria:\n\n• femoro-tibial or patello-femoral osteoarthritis (Kellgren-Lawrence, K-L) grade 2-4 with persistent pain, referred to Kristiansund Hospital for primary TKA\n\nExclusion Criteria:\n\n* serious psychiatric disorders\n* dementia\n* drug abuse\n* patients not able to speak and read Norwegian language making them noncompliant or unable to perform an informed consent\n* Patients with ongoing cancer therapy\n* Patients with ASA (The American Society of Anesthesiologists physical status class risk stratification system) classification \\>3\n* Patients in the need of walking aid devices\n* Patients in need of primary revision arthroplasty or more than 15 degrees of varus or 5 degrees of valgus on preoperative HKA images.",{"count":153,"type":20},152,[23],"Robotic knee surgery makes it possible to adopt different alignment philosophies in total knee arthroplasty. The classical operation where the knee is placed in a neutral manner, the so called mechanical alignment, has been used for decades. The kinematical alignment has recently won popularity. With this technique the focus is to render the natural knee anatomy even if this means to end up with a varus or valgus position. In this study, the investigators will compare the mechanical alignment and kinematical alignment and test the patients clinically and with a special CT scan to see if this technique gives equal or better longevity of the implants.",[157],"Knee Osteoarthritis","2025-06-06",{"date":160,"type":41},"2025-06-11",{"date":162,"type":41},"2024-08-25",{"date":164,"type":20},"2035-05-01",{"name":47,"class":48},{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":16,"minAge":172,"maxAge":58,"enrollmentInfo":173,"targetDuration":4,"studyType":21,"phases":175,"briefSummary":176,"conditions":177,"keywords":179,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":49},"100367005","diabetic-foot-ulcers-shorter-treatment-period-using-custom-felt-relief-100367005","NCT04058639","Diabetic Foot Ulcers: Shorter Treatment Period Using Custom Felt Relief?","Inclusion Criteria:\n\n* diagnosed with Diabetes Mellitus Type 1 or 2\n* has neuropathic wounds under the foot\n* understands and speaks Norwegian well\n* competent to give consent\n\nExclusion Criteria:\n\n* responds to the filament glue and\u002For the tape used in treatment\n* in need of vascular surgery intervention\n* to be admitted to the hospital\n* in need of intravenously administered antibiotics due to wound infection.","45 Years",{"count":174,"type":20},74,[23],"The Surgical Outpatient Clinic at Molde Hospital has since 2015 offered specialized treatment for patients with diabetic foot ulcers. This treatment is given by an interdisciplinary diabetic foot ulcer team. The standard treatment for diabetic foot ulcers is relief, a method with good results.\n\nAlthough the treatment as usual gives good results, the team wants to optimize this treatment. By using custom felt relief for each patient, the treatment period might be reduced considerably. The aim of this study is therefore to investigate whether custom felt relief gives shorter processing time compared to standard relief treatment.",[178],"Diabetic Foot Ulcer",[180,181,182,183],"Bandages","Wound Healing","Time","Relief","2025-03-12",{"date":186,"type":41},"2025-03-14",{"date":188,"type":41},"2019-10-01",{"date":190,"type":20},"2026-03-01",{"name":47,"class":48},{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":16,"minAge":199,"maxAge":4,"enrollmentInfo":200,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":49},"100551306","attr-cardiac-amyloidosis-in-a-selected-population-100551306","NCT06458374","ATTR Cardiac Amyloidosis in a Selected Population","Prevalence and Long Tem Follow Up of ATTR Cardiac Amyloidosis in a Selected Population of Patients Operated on Carpal Tunnel Syndrome","Inclusion Criteria:\n\n* Male \\> 50 years\n* Female \\> 60 years\n* operated CTS at Ålesund Hospital\n\nExclusion Criteria:\n\n* not consented\n* do not speak Norwegian\n* secondary cause of CTS as traumatic or rheumatic\n* cannot be followed \\> 5 years due to other medical conditions\n* Cardiac disease at time of operation for CTS","50 Years",{"count":201,"type":20},180,"Patients operated for carpal tunnel syndrome (CTS) at Ålesund Hospital (200 patients) will have a biopsy to diagnose ATTR amyloidosis. Patients with positive biopsy will be examined to decide wether they have cardiac amyloidosis. All patients with positive biopsy will be followed closely for 10 years wit echocardiography an clinically.",[204,205,206,207],"ATTR Amyloidosis Wild Type","ATTR Gene Mutation","Carpal Tunnel Syndrome","Cardiac Amyloidosis","2024-10-14",{"date":210,"type":41},"2024-10-16",{"date":212,"type":41},"2024-09-01",{"date":214,"type":20},"2039-02-28",{"name":47,"class":48},{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":11,"sex":16,"minAge":223,"maxAge":58,"enrollmentInfo":224,"targetDuration":4,"studyType":21,"phases":226,"briefSummary":227,"conditions":228,"keywords":230,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":236,"lastUpdatePostDateStruct":237,"startDateStruct":239,"completionDateStruct":240,"leadSponsor":242,"locationsCount":49},"100554434","the-ace-avanteon-study---a-randomized-controled-trial-100554434","NCT06499038","The Ace Avanteon Study - A Randomized Controled Trial","Migration Analysis of a Hybrid Hip Replacement Evaluating Stem and Ancillary Acetabular Screw Fixation-A Randomized Controlled CT-RSA Trial","Inclusion Criteria:\n\n* • Patients with primary hip osteoarthritis between the age of 65 and 80 years at time of surgery\n\n  * Patients requiring primary total hip replacement\n  * Patients who understand the conditions of the study, are willing to, and able to comply with the postoperative scheduled clinical and radiographic evaluations\n\nExclusion Criteria:\n\n* • Patients who are unable to provide informed consent\n\n  * Patients who require revision hip arthroplasty\n  * Patients who have had a previous osteotomy or osteosynthesis of the femur or acetabulum\n  * Patients with metabolic bone disease, other than osteoporosis\n  * Patients with inflammatory arthritis\n  * Obese patients where obesity is severe enough to affect the patient's ability to perform activities of daily living (BMI \\> 40)\n  * Patients with active or suspected infection\n  * Patients with malignancy\n  * Patients unable to cooperate caused by language or psychosocial conditions","65 Years",{"count":225,"type":20},60,[23],"The goal of this randomized controled trial is to compare if using of ancillary screws yields equal results as no use of ancillary screws in the ACE acetabulum cup of a total hip arthroplasty. Further, the migration of the Avanteon stem over time will be assessed. Patients included are patients with hip osteoarthritis from 65-80 years old. The purpose of this study is to compare implant migration and early fixation of a hybrid hip replacement combining the uncemented ACE acetabular component and the cemented Avanteon femoral stem, by using CT based Radiostereometric Analysis, a new innovative method for evaluating implant migration. Our study may predict the long term survival of the implants used.\n\nParticipants will go through total hip arthroplasty, and be followed by CT-RSA, plain x-rays and patients reported outcome measures.",[229],"Hip Osteoarthritis",[231,232,233,234,235],", Total Hip Arthroplasty,","Total Hip Replacement","CT-RSA","CTMA","Migration study","2024-08-26",{"date":238,"type":41},"2024-08-28",{"date":162,"type":41},{"date":241,"type":20},"2028-11-01",{"name":47,"class":48},""]