[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hennepin Healthcare Research Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":121},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,73,92],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100602690","phase-1-magnesium-sulfate-in-pediatric-burn-dressing-changes-100602690",false,"NCT07126795","Magnesium Sulfate in Pediatric Burn Dressing Changes","Magnesium Sulfate for Adjuvant Analgesia in Pediatric Burn Dressing Changes: a Pilot Study","Inclusion Criteria:\n\n* \\\u003C 18 years old at time of randomization completion\n* admission to HCMC Burn Unit\n* Projected multi-day sedated dressing change requirement\n* Intention for IV Ketamine as primary analgosedative agent\n\nExclusion Criteria:\n\n* age \\\u003C 3 years (may lower pending FDA discussions)\n* Evidence of hypermagnesemia - pre-study serum Mg2+ level \\> 2.5 mg\u002FdL\n* Evidence of renal dysfunction - serum Cr level \\> 1.5x hospital upper limit normal for age\n* Presence of neuromuscular disease (specifically myasthenia gravis), underlying bradyarrhythmia or heart block\n* Bronchospastic disease (asthma, reactive airway disease) which requires continuous magnesium sulfate infusion\n* Active prescription of a calcium channel blocker (amlodipine, isradipine, nicardipine, nifedipine, clevidipine, diltiazem, verapamil), cardiac glycoside (digoxin), parenteral nutrition or an infusion for hemodynamic support (epinephrine, norepinephrine, dopamine, dobutamine, milrinone, etc)\n* Known allergy or reaction to magnesium sulfate, aluminum, or a component of the formulation\n* Presence of invasive mechanical ventilation\n* Anticipation of skin grafting within 5 days of study eligibility\n* Anyone whom child protective services are consulted\n* Any investigational drug use within 30 days prior to enrollment\n* Pregnant or lactating females\n* Anyone whom in the opinion of the investigator is at higher than anticipated risk of harm or inability to adhere to protocol\n* Patients who choose to opt out of research","ALL","3 Years","18 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","Prospective feasibility trial utilizing adjuvant magnesium sulfate for analgesia\u002Fsedation during pediatric sedated burn dressing changes, which is ultimately hypothesized to decrease ketamine and\u002For sedative requirements.",[27],"Pediatric Burns",[29,30,31,32,33,34],"magnesium sulfate","pediatrics","burn","analgesia","sedation","burn dressing change","NOT_YET_RECRUITING","2025-08-16",{"date":38,"type":39},"2025-08-22","ACTUAL",{"date":41,"type":21},"2026-01-01",{"date":43,"type":21},"2027-01-01",{"name":45,"class":46},"Hennepin Healthcare Research Institute","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":47},"100555627","phase-4-vaccine-immunity-and-inflammation-in-the-aging-person-living-with-hiv-100555627","NCT06514547","Vaccine Immunity and Inflammation in the Aging Person Living With HIV","VIVID","Inclusion Criteria:\n\n* Age\\>=18 years\n* HIV Diagnosis\n* On Antiretroviral Therapy with HIV Viral Load\\\u003C200 within last year\n\nExclusion Criteria:\n\n* Other significant immunosuppressing condition\n* Age\\\u003C 18 years\n* Pregnancy (at enrollment)\n* Contraindication to pneumococcal vaccination\n* Known contraindication to non-clinical blood draws (severe anemia last hemoglobin \\\u003C8g\u002Fdl)\n* Subjects who, in the opinion of the Investigator, may be non-adherent to study schedules or procedures.\n* Adults unable to consent\n* Individuals with impaired ability to consent\n* Incarceration at time of enrollment\n\nControls inclusion criteria:\n\n* Age\\>=18 years\n* HIV Ag-Ab test negative",true,{"count":57,"type":21},250,[59],"PHASE4","This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.",[62,63],"HIV Infections","Age","RECRUITING","2025-06-09",{"date":67,"type":39},"2025-06-12",{"date":69,"type":39},"2024-07-08",{"date":71,"type":21},"2029-06-30",{"name":45,"class":46},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":79,"targetDuration":81,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":86,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":47},"100484436","international-device-assisted-controlled-sequential-elevation-cpr-registry-100484436","NCT05588024","International Device Assisted Controlled Sequential Elevation CPR Registry","Inclusion Criteria\n\n1. Patient is at least 18 years of age\n2. Patient is in active cardiac arrest, as defined by presence of either ventricular fibrillation or ventricular tachycardia, or pulseless electrical activity, or asystole at time of enrollment.\n3. Patient receives either a) active-compression decompression cardiopulmonary resuscitation b) automated suction-cup based CPR with an impedance threshold device (ITD) c) manual CPR with an ITD\n4. Subject receives device assisted controlled elevation of the head and thorax.\n\nExclusion Criteria\n\n1\\. Prisoners",{"count":80,"type":21},5000,"30 Days","OBSERVATIONAL","The purpose of this prospective observational cardiopulmonary resuscitation (CPR) registry is to track the use and clinical outcomes from emergency medical systems across the US and Europe that have implemented a system of care approach applied rapidly to cardiac arrest that includes using the combination of an impedance threshold device (ITD), and either manual active compression-decompression (ACD) CPR device or automated compression device, with a Head Up CPR device.",[85],"Cardiac Arrest, Out-Of-Hospital",{"date":67,"type":39},{"date":88,"type":39},"2020-03-23",{"date":90,"type":21},"2027-06",{"name":45,"class":46},{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":98,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":100,"targetDuration":4,"studyType":22,"phases":102,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":47},"100527385","social-support-counseling-intervention-for-kidney-transplant-candidates-100527385","NCT06147076","Social Support Counseling Intervention for Kidney Transplant Candidates","Journey to Transplant: Virtual Coaching for Potential Kidney Transplant Patients and Their Social Support Networks","JtT","Inclusion\n\n* Determined by transplant center to be suitable for continuation in evaluation for listing (or a member of that person's social support network)\n* 18 Years of age or older\n* English-speaking\n* Willingness to participate with at least 2 social network members in the session and have calculator results shown to social network members (if a patient)\n* Able to provide informed consent\n\nExclusion\n\n* Prisoners\n* Individuals with impaired ability to consent\n* Pregnant females.\n* Patients who choose to opt out of research.\n* Non-English speaking",{"count":101,"type":21},86,[103],"NA","Virtual Coaching for Potential Kidney Transplant Patients",[106],"Kidney Transplant",[108,106,109,110,111,112],"Interventional Counseling","Interventional Mapping","Counseling","Social Support Networks","Dialysis","2024-12-13",{"date":115,"type":39},"2024-12-16",{"date":117,"type":39},"2024-08-20",{"date":119,"type":21},"2026-09",{"name":45,"class":46},""]