[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital Nord\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100608521","evaluation-of-the-variation-of-the-sub-pulmonary-velocity-time-integral-to-predict-fluid-responsiveness-100608521",false,"NCT07202637","Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness","Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness Prospective Observational Study","Inclusion Criteria:\n\n* Patient with measurable sub-pulmonary VTI in at least one of the two windows: parasternal short-axis or subcostal.\n* Patient with measurable sub-aortic VTI in apical 4-chamber view before and after PLR maneuver.\n* Patient with suspected hypovolemia or whose hemodynamic status justifies vasopressor infusion.\n\nExclusion Criteria:\n\n* Severe left ventricular dysfunction defined by left ventricular ejection fraction (LVEF) \\\u003C 30%.\n* Severe right ventricular dysfunction defined by TAPSE \\\u003C 12 mm.\n* Cardiac arrhythmia or atrial fibrillation.\n* Abdominal compartment syndrome.\n* Amputation of one or both lower limbs.\n* Intracranial hypertension.\n* Pregnant women (ruled out by systematic pregnancy test at ICU admission).\n* Minors.","ALL","18 Years",{"count":19,"type":20},205,"ESTIMATED","OBSERVATIONAL","Fluid administration is the first-line treatment in hypovolemic states in critically ill patients. Prediction of fluid responsiveness is possible with echocardiography by assessing the variation of the sub-aortic velocity-time integral (AoVTI) during a passive leg raising test (PLR) or Mini-fluid challenge. However, VTI-Ao measurement is not feasible in all patients due to poor echogenicity. Validation of new fluid-responsiveness indices may facilitate the evaluation in this patient population. Among the available indices, variation of the sub-pulmonary VTI is a potential criterion.",[24,25],"Fluid Resuscitation","Fluid Responsiveness Predictability",[27,28,29,30],"fluid responsiveness","echocardiography","Passive Leg Raising","Mini Fluid Challenge","RECRUITING","2025-09-23",{"date":34,"type":35},"2025-10-02","ACTUAL",{"date":37,"type":35},"2024-11-07",{"date":39,"type":20},"2027-05",{"name":41,"class":42},"Hospital Nord","OTHER",2,""]