[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital San Jose\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100643478","milled-vs-3d-printed-partial-coverage-restorations-in-endodontically-treated-molars-100643478",false,"NCT07643311","Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars","Clinical Performance of CAD\u002FCAM-Milled Versus 3D-Printed Composite Resin Partial-Coverage Restorations for Endodontically Treated Molars: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 to 70 years\n* Absence of active periodontal disease\n* Good oral hygiene (O'Leary plaque index \\\u003C20%)\n* Absence of parafunctional habits (e.g., bruxism, onychophagia)\n* Endodontically treated first molars (maxillary or mandibular) with extensive Class II cavities and loss of at least one cusp, requiring onlay or overlay restoration\n* Tooth with functional occlusal contact and at least one proximal contact\n* Referred from the Endodontics Department of Hospital San José, with endodontic treatment completed at the same institution\n* Ability to provide written informed consent\n* Ability to attend follow-up visits at 12, 24, and 36 months\n\nExclusion Criteria:\n\n* Untreated active periodontal disease\n* Poor oral hygiene (O'Leary plaque index ≥20%)\n* Generalized active caries\n* Active parafunctional habits\n* Teeth with complete circumferential structural destruction or insufficient coronal tooth structure for onlay\u002Foverlay restoration\n* Subgingival margins compromising the biologic width\n* Known allergy to study materials\n* Pregnancy or breastfeeding","ALL","18 Years","70 Years",{"count":20,"type":21},142,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to compare the clinical performance of Computer-Aided Design and Computer-Aided Manufacturing (CAD\u002FCAM)-milled and 3D-printed composite resin partial-coverage restorations in endodontically treated molars.\n\nThe main questions it aims to answer are:\n\n* Do 3D-printed composite resin partial-coverage restorations show similar clinical performance compared with CAD\u002FCAM-milled composite resin restorations?\n* Are there differences in survival, success rates, and complications between the two types of restorations over a 3-year follow-up period?\n\nResearchers will compare CAD\u002FCAM-milled composite resin restorations with 3D-printed composite resin restorations to evaluate their clinical performance.\n\nParticipants will:\n\n* Receive a partial-coverage restoration (onlay or overlay) in an endodontically treated molar.\n* Be randomly assigned to receive either a CAD\u002FCAM-milled or a 3D-printed composite resin restoration.\n* Attend follow-up visits at 12, 24, and 36 months.\n* Undergo clinical evaluations by two blinded evaluators using the revised FDI criteria and standardized photographic documentation.",[27],"Endodontically Treated Teeth",[29,30,31,32,33,34,35,36,37],"Onlay","Overlay","Milled Composite Resin","3D-Printed Composite Resin","partial coverage restoration","CAD\u002FCAM","3D printing","Indirect restoration","FDI Criteria","RECRUITING","2026-06-09",{"date":41,"type":42},"2026-06-11","ACTUAL",{"date":44,"type":42},"2026-05-29",{"date":46,"type":21},"2030-06-30",{"name":48,"class":49},"Hospital San Jose","OTHER",""]