[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital Son Llatzer\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":101},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100634059","minimaly-ivnasive-surgery-for-grade-iii-hemorrhoids-100634059",false,"NCT07534761","Minimaly Ivnasive Surgery for Grade III Hemorrhoids","Prospective Observational Study to Assess the Reproducibility of Minimally Invasive Surgery in Closed Excisional Hemorrhoidectomy: Phase 2A of theI DEAL Framework","Inclusion Criteria:\n\n* Age over 18 years\n* Grade III\u002FIV hemorrhoids\n* Indication for CEH surgery\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Acute hemorrhoidal disease (thrombosis)\n* Previous hemorrhoid surgery\n* Coexistence of anal fissure\n* Coexistence of perianal fistula\n* Coexistence of rectal or anal prolapse\n* Active inflammatory bowel disease\n* Active anal or colorectal cancer\n* Language barrier or difficulty in oral and\u002For written comprehension","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","1 Year","OBSERVATIONAL","Hemorrhoids are vascular-elastic structures of the anal canal that contribute to continence. Their enlargement and descent lead to symptoms such as rectal bleeding and the sensation of anal swelling, known as hemorrhoidal syndrome. In advanced cases (Goligher Grade III-IV), surgery is the only effective treatment. Closed excisional hemorrhoidectomy (CEH), based on the Ferguson technique, is one of the standard procedures. Although effective in the long term, it causes severe postoperative pain. Minimally invasive surgery (MIS) employs enhanced visualization devices to improve surgical precision and reduce tissue damage. While widely used in specialties with small surgical fields, it has not yet been explored in anal surgery. Its advantages include reduced tissue injury and improved healing, although it presents a learning curve and an initially longer surgical time. The IDEAL framework evaluates surgical innovations in five stages: Idea, Development, Exploration, Evaluation, and Long-Term Study. The IDEAL phase 2a is aimed at the optimization and technical definition of surgical innovation with a focus on continuous improvement based on real clinical practice, laying the foundation for broader and more rigorous subsequent studies.\n\nSince no previous studies on the application of MIS in CEH have been found, the investigators propose a study within Stage 2A of the IDEAL model to assess the reproducibility of this technique. The investigators believe its incorporation into closed excisional hemorrhoidectomy could result in less postoperative pain and faster patient recovery.",[25,26],"Hemorrhoidectomy","Minimally Invasive Surgical Technique",[28,25,29,30],"hemorrhoids grade III-IV","IDEAL stage 2A","minimally Invasive Surgical Technique","NOT_YET_RECRUITING","2026-04-16",{"date":34,"type":35},"2026-04-21","ACTUAL",{"date":37,"type":20},"2026-06-01",{"date":39,"type":20},"2027-12-01",{"name":41,"class":42},"Hospital Son Llatzer","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":43},"100553328","efficacy-of-minimally-invasive-approach-in-the-surgical-treatment-of-complex-perianal-fistula-100553328","NCT06484660","Efficacy Of Minimally Invasive Approach In The Surgical Treatment Of Complex Perianal Fistula","Efficacy Of Minimally Invasive Approach In The Mucosal Advancement Flap Technique For The Surgical Treatment Of Previously Untreated Complex Perianal Fistula","Inclusion Criteria:\n\n* Age older than 18.\n* Present with a complex perianal fistula not surgically treated with curative intention.\n* Present only one main fistulous tract.\n* Mucosal advancement flap as the chosen technique for the treatment of the fistula.\n* Patient has given informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Non-cryptoglandular internal fistulous orifice (IFO).\n* Extrasphincteric fistula.\n* Coexistence of anal fissure.\n* Coexistence of hemorrhoids tributary to surgery.\n* Coexistence of anal or rectal prolapse.\n* Coexistence of inflammatory bowel disease.\n* Coexistence of anal or colorrectal cancer.",{"count":52,"type":20},40,"INTERVENTIONAL",[55],"NA","The goal of this clinical trial is to study whether the minimally invasive approach in the mucosal advancement flap technique for the treatment of complex perianal fistula improves the healing rate compared to non-minimally invasive surgery.\n\nThe main question it aims to answer is:\n\n\\- Does the healing rate of patients undergoing minimally invasive approach in the mucosal advancement flap technique improve compared to patients undergoing non-minimally invasive surgery?\n\nResearchers will also compare minimally invasive approach in the mucosal advancement flap technique to the non-minimally invasive approach in terms of postoperative pain, fecal incontinence and healing time.\n\nQuality of life and global morbidity will also be analyzed.\n\nParticipants will:\n\n* Undergo surgical treatment of complex perianal fistula performed by mucosal advancement flap performed by a minimally invasive technique.\n* Attend control visits and fill in symptom forms one week, one month, three months and six months after the surgical procedure.",[58],"Fistula Perianal",[60,61,62],"Perianal Fistula","Mucosal Advancement Flap","Minimally Invasive Approach","RECRUITING","2025-08-26",{"date":66,"type":35},"2025-09-03",{"date":68,"type":35},"2021-08-01",{"date":70,"type":20},"2025-12-31",{"name":41,"class":42},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":53,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":43},"100279264","ultrasound-guided-pulsed-radiofrequency-in-the-treatment-of-patients-with-osteoarthritis-knee-usprfgenoak-100279264","NCT02915120","Ultrasound-Guided Pulsed Radiofrequency In The Treatment Of Patients With Osteoarthritis Knee (USPRFGENOAK)","Ultrasound-Guided Pulsed Radiofrequency Of The Genicular Nerves In The Treatment Of Patients With Osteoarthritis Knee Pain: Randomized, Double-Blind, Placebo Controled Trial","USPRFGENOAK","Inclusion Criteria:\n\n* Chronic knee pain with pain intensity of at least 4 out 10 on the VAS on most or all days for more than 3 months\n* Patients of either sex with primary osteoarthritis of one or both knees fulfilling diagnostic criteria for osteoarthritis knee laid down by American College of Rheumatology.\n* Patients also had to have a Kellgren-Lawrence (radiologic criterion) score of at least 2\n* Pain resistant to conventional therapy including NSAIDs, opioids, muscle relaxants, oral steroids, physical therapy, and intra-articular injection therapy.\n\nExclusion Criteria:\n\n* The patients with secondary osteoarthritis of knees\n* Associated systemic arthropathies, e.g. rheumatoid arthritis and gout\n* Previous radiofrequency ablation treatment for similar symptoms.\n* Intra-articular knee corticosteroid or hyaluronic acid injection in the past 3 months.\n* Active systemic or local infections at the site of proposed needle and electrode placement.\n* Coagulopathy or other bleeding disorder\n* Cognitive deficit.\n* Unstable medical or psychiatric illness.\n* Previous knee joint replacement surgery\n* Patients missing two or more appointments consecutively were excluded from the study","40 Years",{"count":82,"type":20},142,[55],"The purpose of this study is to determine if patients with chronic painful knee osteoarthritis experience meaningful and long-term improvement in pain, function, and analgesic use after ultrasound-guided pulsed radiofrequency of the genicular nerves following a double diagnostic genicular nerve blocks.",[86],"Osteoarthritis, Knee",[88,89,90,91,92],"Knee pain","osteoarthritis","genicular nerve","ultrasonography","pulsed radiofrequency","2024-11-08",{"date":95,"type":35},"2024-11-12",{"date":97,"type":35},"2017-03-27",{"date":99,"type":20},"2024-12",{"name":41,"class":42},""]