[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital Universitario Mayor Méderi\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100624649","predictive-factors-for-functional-and-quality-of-life-decline-in-patients-65-years-with-a-gastrointestinal-tract-cancer-diagnosis-taken-to-curative-resectable-surgery-100624649",false,"NCT07412379","Predictive Factors for Functional and Quality of Life Decline in Patients >65 Years With a Gastrointestinal Tract Cancer Diagnosis Taken to Curative Resectable Surgery","Predictive Factors Associated With Functional Decline and Quality of Life Decline at 12 Months Follow-up and 5 Year Oncological Follow-up in Patients >65 Yares With a Gastrointestinal Tract Cancer Diagnosis Taken to Resectable Surgery With a Curative Intent in Hospital Universitario Mayor-Méderi, Bogotá, Colombia","Inclusion Criteria:\n\n* Gastrointestinal cancer tract diagnosis (oesophagus, stomach, duodenum, pancreas, liver, biliary tract, small bowel, appendix, colon and rectum)\n* Have resectable disease by surgery\n* Taken to surgery by curative intent\n* Willingness to participate and enrollment by informed consent\n* Attended in the Mederi Hospital Networn\n\nExclusion Criteria:\n\n* Mortality\n* Loss to follow-up\n* Not taken to surgery\n* Emergency surgery\n* Taken to surgery as an oncological relapse or due to complications previous to an index procedure\n* Endoscopical treatment\n* Second primary tumor without a minimum 5 year disease free period from the primary one\n* Basal functionality 0\u002F6 by Katz score.","ALL","65 Years",{"count":19,"type":20},327,"ESTIMATED","5 Years","OBSERVATIONAL","Introduction: Human life expectancy has increased significantly, leading to a transformation in the global demographic structure. Cancer is considerably more common among older adults compared to younger populations, as age is one of the main risk factors for its development. In fact, most solid tumors are considered age-related diseases. For this reason, the incidence of cancer among older individuals is expected to continue rising. Oncological care for this population group is particularly complex and represents a significant challenge, as comorbidities and the social aspects of aging create clinical scenarios that differ greatly from those seen in younger patients.\n\nObjective: To identify the predictive factors of functional decline and quality of life at 12 months of follow-up, as well as oncological outcomes at 5 years of follow-up, in patients aged 65 years and older with gastrointestinal cancer who undergo curative-intent resective surgery at Hospital Universitario Mayor - Méderi, Bogotá, Colombia.\n\nMethodology: Longitudinal and analytical observational study of prospective prognostic cohort type.\n\nExpected Results: Predictive model of functional decline and quality of life, as well as oncological outcomes, in patients with gastrointestinal cancer undergoing curative-intent surgical procedures.",[25,26,27,28,29],"Cancer Abdomen","Elderly (People Aged 65 or More)","Quality of Life","Sarcopenia in Elderly","Functional Autonomy Level","RECRUITING","2026-02-09",{"date":33,"type":34},"2026-02-17","ACTUAL",{"date":36,"type":34},"2026-01-13",{"date":38,"type":20},"2029-12-15",{"name":40,"class":41},"Hospital Universitario Mayor Méderi","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":5},"100524798","timing-of-cholecystectomy-in-severe-pancreatitis-100524798","NCT06113419","Timing of CHolecystectomy In Severe PAncreatitis","Timing of CHolecystectomy In Severe PAncreatitis (CHISPA): Study Protocol for a Randomized Controlled Trial.","CHISPA","Inclusion Criteria:\n\n* Age ≥18 years, diagnosis of pancreatitis according to Atlanta guidelines, moderately severe or severe pancreatitis (APACHE score ≥8 on admittance)\n* Biliary pancreatitis diagnosed on imaging (be it ultrasound, magnetic resonance imaging and\u002For tomography)\n* Recovery of pancreatitis by tolerance of oral intake (defined as 24 hours of food consumption of any consistency without emetic episodes and pain defined as 4\u002F10 on the visual analogue score of pain) and written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy\n* History of cholecystectomy\n* Planned open cholecystectomy\n* Pancreatitis-associated complication before laparoscopic cholecystectomy (compartment syndrome, bleeding and\u002For need for peripancreatic collection drainage)\n* Chronic pancreatitis,\n* More than one episode of pancreatitis\n* Active malignant disease\n* Septic shock\n* Choledocholithiasis not resolved by ERCP, post-ERCP perforation and post-ERCP concomitant pancreatitis.","18 Years",{"count":53,"type":20},134,"INTERVENTIONAL",[56],"NA","The goal of this clinical trial is to compare outcomes for interval or early laparoscopic cholecystectomy in patients with moderately severe and severe pancreatitis. The main question\\[s\\] it aims to answer are:\n\n* To establish whether there is a difference in surgical outcomes comparing patients diagnosed with severe or moderately severe pancreatitis on which early cholecystectomy was performed versus performing interval cholecystectomy.\n* The primary endpoint will be to evaluate major complications, defined as a Clavien-Dindo score greater than or equal to III\u002FV.\n* Secondary endpoints include evaluating minor complications (defined as a Clavien-Dindo score below III\u002FV), biliary disease recurrence, mortality, postoperative hospital stay and postoperative admittance into an intensive care unit.\n\nParticipants will be randomly assigned to either group: early cholecystectomy during the pancreatitis hospitalization or interval cholecystectomy scheduled 4 weeks after clinical resolution of pancreatitis.",[59,60],"Acute Pancreatitis","Cholelithiasis",[62,59,60],"cholecystectomy","2025-09-09",{"date":65,"type":34},"2025-09-15",{"date":67,"type":34},"2024-04-01",{"date":69,"type":20},"2027-06",{"name":40,"class":41},""]