[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital of Stomatology, Sun Yat-Sen University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":62},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,36],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":31,"leadSponsor":33,"locationsCount":4},"100583453","clinical-efficacy-of-different-maxillary-sinus-floor-elevation-procedures-100583453",false,"NCT06876519","Clinical Efficacy of Different Maxillary Sinus Floor Elevation Procedures","Clinical Efficacy of Different Maxillary Sinus Floor Elevation Procedures Based on Maxillary Sinus Anatomy","Inclusion Criteria:\n\n* Patients undergoing translateral maxillary sinus floor elevation or hydraulic transcrestal maxillary sinus floor elevation in the maxillary molar region.\n* Patients undergoing maxillary sinus floor elevationwith simultaneous implantation in the maxillary molar region，and having successful osseointegration after 6 months from surgery.\n* Patients having CBCT examination for preoperative, the day of surgery, and six months after surgery.\n* Patients treated between January 1, 2016 and June 30, 2024.\n\nExclusion Criteria:\n\n* Patients having osteointegration failure within six months after surgery.\n* Refusal to participate in the study.\n* Other conditions deemed unsuitable for participation by the investigator.","ALL","18 Years",{"count":19,"type":20},43,"ESTIMATED","OBSERVATIONAL","The goal of this study is to investigate the clinical efficacy of different maxillary sinus floor elevation procedures based on maxillary sinus anatomy.\n\nThe main questions it aims to answer are:\n\n* How does the anatomical morphology of maxillary sinus affect postoperative bone resorption?\n* How to select the appropriate maxillary sinus floor elevation procedure based on maxillary sinus anatomy? Preoperative, immediate postoperative, and six-month postoperative CBCT images of patients undergoing translateral maxillary sinus floor elevation or hydraulic transcrestal maxillary sinus floor elevation will be measured.",[24],"Maxillary Sinus Floor Elevation","NOT_YET_RECRUITING","2025-03-10",{"date":28,"type":29},"2025-03-14","ACTUAL",{"date":26,"type":20},{"date":32,"type":20},"2025-06-30",{"name":34,"class":35},"Hospital of Stomatology, Sun Yat-Sen University","OTHER",{"id":37,"slug":38,"hasResults":11,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":4,"eligibilityCriteria":42,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":43,"enrollmentInfo":44,"targetDuration":4,"studyType":46,"phases":47,"briefSummary":49,"conditions":50,"keywords":4,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},"100569284","efficacy-and-safety-of-additive-manufacturing-personalized-titanium-mesh-in-guided-bone-regeneration-100569284","NCT06692244","Efficacy and Safety of Additive Manufacturing Personalized Titanium Mesh in Guided Bone Regeneration","Efficacy and Safety of Additive Manufacturing Personalized Titanium Mesh in Guided Bone Regeneration: a Randomized, Single-blind, Positive-controlled Prospective Study","Inclusion Criteria:\n\n1. Patients missing single or multiple teeth with moderate to severe bone defects in the edentulous area requiring complex guided bone regeneration. （Moderate bone defects: bone loss with residual alveolar ridge width between 1 mm and 3 mm; severe bone defects: bone loss with residual alveolar ridge width ≤ 1 mm.）\n2. The edge of the edentulous area within 1 mm is alveolar bone, with no adjacent tooth roots or nerve canals, ensuring complete retention of the personalized titanium mesh edge. The apical edge of the edentulous area within 2 mm is alveolar bone, with no nerve canals, ensuring that retention screws for the personalized titanium mesh can be designed in this area.\n3. The patient and\u002For his\u002Fher guardian agrees to participate in this trial and signs the informed consent form.\n\nExclusion Criteria:\n\n1. Patients with edentulism.\n2. Patients with mild bone defects (residual alveolar ridge width greater than 3 mm).\n3. Presence of acute or chronic infection in the surgical area.\n4. Presence of acute or chronic infection in the teeth adjacent to the edentulous area.\n5. Participation in similar trials or other interventional clinical trials within 30 days prior to signing the informed consent form.\n6. History of metal allergies, severe allergy history, or severe immune deficiency.\n7. Uncontrolled metabolic diseases, such as Type 1 diabetes or Type 2 diabetes (HbA1c ≥ 7% or fasting blood glucose ≥ 7 mmol\u002FL despite medication control), severe liver or kidney dysfunction (ALT, AST \\> 2 times the upper limit of normal, serum creatinine above the upper limit of normal).\n8. Long-term use of steroid medications.\n9. History of drug abuse or alcoholism.\n10. Pregnant or breastfeeding women.\n11. Poor compliance.\n12. Other conditions deemed unsuitable for participation by the investigator.","60 Years",{"count":45,"type":20},142,"INTERVENTIONAL",[48],"NA","This goal of this single-blind, simple randomized, positive-controlled prospective study is to evaluate the effects of additive-manufactured personalized titanium mesh and traditional titanium mesh in guided bone regeneration for large alveolar bone defects. The study will assess the short-term and long-term efficacy, safety, and incidence of complications of the additive-manufactured personalized titanium mesh, along with an analysis of risk factors. Participants will be followed up for two years after surgery with free-of-charge clinical and radiographic examinations.",[51,52],"Alveolar Bone Atrophy","Guided Bone Regeneration","RECRUITING",{"date":55,"type":29},"2025-03-11",{"date":57,"type":29},"2024-11-30",{"date":59,"type":20},"2028-12",{"name":34,"class":35},1,""]