[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Howard University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100625074","brave-program-to-improve-safety-and-reduce-violence-risk-in-early-psychosis-100625074",false,"NCT07417904","BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis","Young Adults and Violent Behavior During Early Psychosis (Aim 3)","BRAVE","Inclusion Criteria:\n\n* Young adults aged 18-30 years\n* Diagnosis of early psychosis\n* Currently receiving outpatient care through an early psychosis clinic\n* Psychiatrically stable and deemed appropriate for participation by a treating clinician\n* Able and willing to provide informed consent\n\nExclusion Criteria:\n\n* Unable to provide informed consent\n* Not fluent in English\n* History of antisocial behavior, as assessed at baseline\n* Immediate risk requiring a higher level of care","ALL","18 Years","30 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study evaluates the feasibility and acceptability of BRAVE, a manualized cognitive behavioral therapy (CBT)-based intervention designed to address dynamic risk factors for violence among young adults with early psychosis. Using a stepped-wedge randomized design, all participants will receive treatment as usual followed by the BRAVE intervention. The study will also explore changes in violence-related behaviors and treatment engagement over time.",[28,29],"Violence Risk","Early Psychosis",[31,32,33,34],"early psychosis","violence risk","aggression","cognitive behavioral therapy","NOT_YET_RECRUITING","2026-02-10",{"date":38,"type":39},"2026-02-18","ACTUAL",{"date":41,"type":22},"2026-02-16",{"date":43,"type":22},"2026-08",{"name":45,"class":46},"Howard University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100548056","integrating-moud-in-nonmedical-community-settings-better-together-100548056","NCT06416020","Integrating MOUD in Nonmedical Community Settings (Better Together)","Inclusion Criteria\n\n1. Be 16 years of age or older\n2. Has been newly prescribed MOUD with buprenorphine by a hub clinic provider no more than 10 days before the day of randomization or on the day of randomization \\[Note that the \"start\" of a \"current, new treatment episode\" of MOUD with buprenorphine is defined as the date MOUD with buprenorphine was prescribed by a hub clinic provider.\\]\n3. Is willing and able to provide written informed consent\n4. Is willing and able to provide reliable locator information to facilitate contacting the participant for research follow-up assessments\n5. Speaks English well enough to be able to comprehend the study procedures and complete the assessments\n\nExclusion Criteria:\n\n1. In the 30 days prior to receiving the prescription for MOUD with buprenorphine from the hub clinic provider, has either taken prescribed MOUD as an outpatient for more than 10 consecutive days OR received injectable MOUD that covers more than 10 consecutive days \\[Note that receipt of MOUD in a hospital, residential treatment, or carceral setting would not trigger exclusion.\\]\n2. Plans to move out of the area or anticipate not being able to remain in the study for 6 months\n3. Is currently in jail, prison, or other overnight facility as required by a court of law or have pending legal action that could prevent participation in study activities\n4. Has been previously enrolled in CTN-0144 or CTN-0088 or is currently enrolled in another clinical trial for treatment of OUD","16 Years",{"count":56,"type":22},400,[25],"A multisite effectiveness-implementation study will be conducted in four sites to evaluate interventions to improve engagement and retention in MOUD with buprenorphine treatment persons with Opioid Use Disorder (OUD) in urban neighborhoods with high overdose rates. The investigators hypothesize that treatment with the Better Together Integrated Collaborative Community MOUD care model (BT-MOUD) will result in better retention in treatment than standard-of-care MOUD with buprenorphine provided in the hub buprenorphine clinic only (HC-MOUD Only) through 24 weeks following randomization. BT-MOUD provides MOUD with buprenorphine in nonmedical community-based settings via telemedicine from a hub buprenorphine clinic combined with Recovery Guiding, a manual guided coaching developed for this approach, provided onsite in the community organization.",[60],"Opioid Use Disorder",[62,63,64],"MOUD","OUD","Buprenorphine","2025-11-25",{"date":67,"type":39},"2025-12-03",{"date":69,"type":22},"2026-01-26",{"date":71,"type":22},"2028-07",{"name":45,"class":46},4,""]