[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hyundae Meditech\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":13,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100624650","study-of-diosha-s-lido-injection-vs-youthfill-fine-with-lidocaine-in-treating-moderate-to-severe-nasolabial-folds-100624650",false,"NCT07412392","Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds","A Multi Center, Randomized, Subject & Independent Evaluator-blinded, Matched Pairs, Active Controlled, Non-inferiority, Pivotal Study to Evaluate the Efficacy and Safety of Injection With DIOSHA S Lido as Compared to YOUTHFILL(YOUTHFILL Fine With Lidocaine) in Temporary Correction of Moderate to Severe Nasolabial Folds","Inclusion Criteria:\n\n* Adults aged 19 to 75 years\n* Voluntarily provided written informed consent\n* Moderate to severe symmetrical nasolabial folds (WSRS score 3 or 4 on both sides)\n* Agree to discontinue other facial dermatologic treatments (e.g., fillers, botulinum toxin, laser) during the study\n* Able to understand instructions and comply with study procedures\n\nExclusion Criteria:\n\n* Active facial skin disease, infection, or untreated scars in the treatment area\n* History of severe allergy or hypersensitivity to device components\n* Facial aesthetic or invasive procedures in the treatment area within 6 months prior to screening\n* Use of prohibited medications within required washout periods\n* Participation in another interventional clinical trial within 4 weeks prior to screening or during the study\n* Pregnancy, breastfeeding, or non-compliance with contraception requirements\n* Any condition deemed inappropriate by the investigator",true,"ALL","19 Years","75 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA",[27],"Nasolabial Folds, Wrinkles","NOT_YET_RECRUITING","2026-02-09",{"date":31,"type":32},"2026-02-17","ACTUAL",{"date":34,"type":22},"2026-02-27",{"date":36,"type":22},"2027-07-30",{"name":38,"class":39},"Hyundae Meditech","INDUSTRY",""]