[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"IMDEA Food\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":99},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,61],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":4},"100640704","food-i-sense-analytics-integrating-ai-into-continuous-glucose-monitoring-data-analysis-for-precision-nutrition-100640704",false,"NCT07626658","Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition.","Food_i Sense Analytics: Integrando la Inteligencia Artificial Con la monitorización Continua de la Glucosa Para la nutrición de precisión","Food_i Sense","Inclusion Criteria:\n\n* Adults aged 18 to 70 years.\n* Willing and able to undergo 14 days of continuous glucose monitoring (CGM) using a wearable sensor.\n* Able to maintain stable dietary habits during the monitoring period.\n* Able and willing to complete dietary records, including two structured 3-day food logs.\n* Able and willing to photograph all meals during the 14-day monitoring period following instructions provided.\n* Able to keep a record of physical activity as instructed.\n* No previous diagnosis of diabetes or other serious metabolic disorders.\n* Sufficient commitment and availability to attend all study visits (screening, baseline evaluation, final evaluation).\n* Capable of providing written informed consent.\n\nExclusion Criteria:\n\n* Diagnosed diabetes mellitus or other serious metabolic disorders.\n* History of severe gastrointestinal, cardiovascular, or other medical conditions that may interfere with stable diet or physical activity during the study.\n* Pregnant or breastfeeding women.\n* Inability or unwillingness to comply with continuous glucose monitoring (CGM) procedures for 14 days.\n* Participants with skin conditions or allergies that prevent safe use of a CGM sensor.\n* Current participation in another clinical trial that could affect study results.\n* Use of medications that significantly alter glucose metabolism or interfere with CGM accuracy.\n* Inability to attend all scheduled study visits or complete required records (diet logs, photos, questionnaires).\n* Any condition judged by the investigators to make the participant unsuitable for the study or unable to provide informed consent.",true,"ALL","18 Years","70 Years",{"count":22,"type":23},471,"ESTIMATED","OBSERVATIONAL","This study aims to improve how we understand and manage blood sugar responses in adults without diabetes. Even in people who appear healthy, blood sugar levels after meals can behave in different ways. These patterns may help predict future risk of diseases such as type 2 diabetes or other cardiometabolic problems.\n\nTo study this, researchers at IMDEA Nutrition have developed a computer algorithm called GLIA, which uses artificial intelligence (AI) to analyze continuous glucose monitoring (CGM) data. The goal is to classify people into different \"glucotypes\", meaning typical patterns of how their blood sugar behaves throughout the day. These glucotypes could help tailor dietary recommendations in the future.\n\nGoals of the study\n\n1. Train and validate the GLIA algorithm\\*\\* in a large and diverse sample of adults.\n2. Study how glucotypes relate to health indicators\\*\\*, such as blood pressure, body composition, cholesterol, or lifestyle.\n3. Predict how each person responds to different foods\\*\\*, to support personalized nutrition advice.\n\nWho can participate?\n\nAdults 18-70 years old who:\n\n* Do not\\*have diagnosed diabetes or serious metabolic disease.\n* Agree to wear a glucose sensor for 14 days.\n* Can keep stable eating habits and record diet and physical activity.\n\nWhat participation involves\n\nThe study lasts 3 weeks and includes 3 visits:\n\nVisit 1 - Screening (20 min):\n\n* Review of eligibility criteria.\n* Explanation of the study.\n* Signing informed consent.\n* Visit 2 - Initial assessment (45 min)\n* Collection of personal and health information.\n* Measurements: weight, height, waist, body composition, blood pressure.\n* Placement of a FreeStyle Libre 3 CGM sensor.\n* Instructions for:\n* Completing two 3-day food records (one each week).\n* Taking photos of all meals.\n* Reporting physical activity.\n\nContinuous monitoring (14 days)\n\nVisit 3 - Final evaluation (45 min)\n\n* Review of diet records.\n* Repeat measurements.\n* Blood and urine samples are collected for metabolic and molecular analyses.\n\nMeal photos are analyzed using an AI-based food recognition model. The system identifies foods and estimates nutrients (macronutrients, vitamins, minerals, glycemic index, etc.). This helps researchers understand how meals relate to blood sugar patterns.\n\nPotential benefits: Although participants may not receive direct health benefits, the study will:\n\n* Improve understanding of how healthy people process glucose.\n* Help identify early risk markers for metabolic diseases.\n* Contribute to developing \\*\\*personalized nutrition tools\\*\\* based on individual glucose responses.\n\nRisks: are minimal and mainly include:\n\n* Mild skin irritation from the CGM sensor.\n* Temporary discomfort from blood draw.",[27,28],"Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)","Artificial Intelligence Mobile Application",[30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48],"Continuous glucose monitoring (CGM)","Glucose dynamics","Glucose phenotyping","Glucotypes","Artificial intelligence","Nutrition","Machine-learning","Glucose patterns","Precision nutrition","Chrononutrition","Glycemic variability","Nutritional pattern","Glycemic response modeling","Personalized dietary recommendations","Multimodal metabolic phenotyping","Wearable glucose sensors","AI-driven health monitoring","Cardiometabolic health","Adults Without Diabetes","NOT_YET_RECRUITING","2026-06-02",{"date":52,"type":53},"2026-06-04","ACTUAL",{"date":55,"type":23},"2026-07",{"date":57,"type":23},"2028-12",{"name":59,"class":60},"IMDEA Food","OTHER",{"id":62,"slug":63,"hasResults":11,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":11,"sex":18,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":4,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":81,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},"100582024","improving-health-and-reducing-chronic-disease-risk-in-middle-aged-adults-through-nutrition-100582024","NCT06857929","\"Improving Health and Reducing Chronic Disease Risk in Middle-Aged Adults Through Nutrition\"","Nutritional Approach for the Transformation and Reduction of Chronic Disease Indicators in Middle-aged Adults at High Risk","NUTRI-M-Care","Inclusion Criteria:\n\n* BMI 27-40 Kg\u002Fm2\n* Metabolic syndrome according to International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity\n* Stable weight in the last 3 months (weight changes \\\u003C 4Kg)\n* Be able to give informed consent\n\nExclusion Criteria:\n\n* Have a diagnosed illness that interferes with the recommendations proposed in the intervention.\n* Women with established menopause.\n* Pregnant or breastfeeding women.\n* Serious psychiatric illness\u002Fdisorder.\n* Social, cultural or psychological factors that may affect adherence to the intervention protocol.\n* Inability to communicate with study staff.\n* Inability to follow recommended diet or inability to engage in physical activity.\n* Low likelihood of modifying dietary habits according to the different stages of change according to the Prochaska and DiClemente model.\n* Difficulty attending scheduled appointments within the intervention due to work schedule conflicts, travel plans, scheduled surgeries, among other reasons.\n* Therapeutic non-compliance.\n* Participating in a professionally-led nutritional intervention.\n* Being under medical treatment that affects weight, intake or energy expenditure in the 3 months preceding the start of the study.\n\nSmokers who have changed their smoking habit in the 6 months preceding the start of the study (including starting or stopping smoking).\n\n\\- Participation in another trial that may interfere with this proposed study.","30 Years","50 Years",{"count":72,"type":23},106,"INTERVENTIONAL",[75],"NA","The goal of this clinical trial is to evaluate the effect of a multifactorial lifestyle intervention combining Mediterranean diet, energy reduction and physical activity on weight loss in middle-aged adults (men and women 30-50 years old) with metabolic syndrome. The main questions it aims to answer are:\n\nIs a multifactorial intervention based on Mediterranean diet, energy reduction and physical activity able to promote weight loss maintenance in middle-aged men and women with metabolic syndrome? syndrome? Which are the sociodemographic barriers to adhere to a multifactorial lifestyle intervention to promote cardiometabolic health? How is the lifestyle pattern of middle-aged Spanish adults with metabolic\n\nResearchers will compare a multifactorial lifestyle intervention combining Mediterranean diet, energy reduction and physical activity to a control intervention based on usual primary healthcare to see if the intervention improve cardiometabolic traits and promote weight loss maintenance after 1 year.\n\nParticipants in the intervention arm will be asked to follow an energy-reduced Mediterranean diet plus a physical activity program with the aim of reducing 5-10% of the initial weight in 6 months and of maintaining the weight lost after 1 year o follow-up.",[78,79,80],"Metabolic Syndrome","Obesity Prevention","Obesity and Overweight",[82,83,84,85,86,87,88],"metabolic syndrome","Mediterranean diet","Caloric restriction","Physical activity","Weight loss","Weight","body composition","RECRUITING","2026-03-23",{"date":92,"type":53},"2026-03-27",{"date":94,"type":53},"2026-03-01",{"date":96,"type":23},"2028-09-30",{"name":59,"class":60},1,""]