[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ilya Lukin\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":51},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100614408","pace-af-prospective-analysis-of-cardiac-electrostimulation-and-atrial-fibrillation-100614408",false,"NCT07279207","PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation","Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation (PACE-AF)","PACE-AF","Inclusion Criteria:\n\n* • Age ≥ 18 years\n\n  * Implantation of a dual-chamber permanent pacemaker\n  * Ability to provide informed consent\n  * Willingness to participate in long-term follow-up\n\nExclusion Criteria:\n\n* • Single-chamber pacemaker or Cardiac Resynchronization Therapy device at baseline\n\n  * Life expectancy \\\u003C 1 year due to non-cardiac comorbidities\n  * Inability to comply with follow-up visits or device interrogation\n  * Participation in another clinical trial that could interfere with study endpoints","ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","3 Years","OBSERVATIONAL","PACE-AF is a prospective, observational patient registry designed to evaluate the impact of pacemaker algorithms on atrial fibrillation (AF) incidence, progression, and clinical outcomes in patients implanted with dual-chamber pacemakers. The registry aims to include 400-500 patients with longitudinal follow-up. Primary outcomes are progression to permanent AF and all-cause mortality. Secondary outcomes include quality of life, hospitalization, and cardiovascular events.",[26,27,28],"Atrial Fibrillation","Sick Sinus Syndrome","Atrioventricular Block",[30,31,32,33,34,35,36,37,38],"Pacemaker","Dual-chamber pacing","Pacemaker algorithms","Conduction system pacing","His bundle pacing","Left bundle branch pacing","Catheter ablation","Cryoablation","Arrhythmia prevention","NOT_YET_RECRUITING","2025-11-30",{"date":42,"type":43},"2025-12-12","ACTUAL",{"date":45,"type":21},"2025-12",{"date":47,"type":21},"2028-12",{"name":49,"class":50},"Ilya Lukin","OTHER",""]