[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Indus Hospital and Health Network\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100617104","phase-4-meropenem-vs-azithromycin-efficacy-in-case-xdr-enteric-fever-100617104",false,"NCT07314281","Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever","\"Comparing Efficacy of Intravenous Azithromycin and Meropenem for Extensively Drug-Resistant Enteric Fever: A Randomized Controlled Trial\" (Pilot Study)","Inclusion Criteria:\n\n* Participants will enrolled on following criteria\n\n  * Voluntarily sign the written informed consent\n  * Patient's of age 1-70 years with clinically suspected on physician decision or XDR enteric fever confirmed by blood culture and sensitivity tests.\n  * Married females with negative pregnancy test.\n  * No history of cardiac issues with ECG abnormalities, cholestatic jaundice\u002Fhepatic dysfunction associated with prior azithromycin use.\n  * Patients having no hypersensitivity (skin rashes, anaphylaxis) to azithromycin and meropenem\n  * Patients on concomitant medication, having no drug-drug interaction with meropenem and azithromycin will be included in study.\n\nExclusion Criteria:\n\n* Participants will excluded on following criteria\n\n  * Pregnant, lactating women or women of childbearing age with positive pregnancy test at baseline.\n  * Patients with known hypersensitivity (skin rashes, anaphylaxis) to azithromycin, meropenem, or any other macrolide or carbapenem antibiotics.\n  * Blood culture and sensitivity tests reported positive culture with MDR S. typhi (non-susceptibility to at least one agent in three or more antimicrobial categories,) o\n  * Patients with history of cardiac disorder with ECG abnormalities and history of cholestatic jaundice\u002Fhepatic dysfunction associated with prior azithromycin use will be excluded.\n  * Patients on continuous medication, having drug-drug interaction with meropenem and azithromycin will be excluded.","ALL","1 Year","70 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","1. Primary Objective:\n\n   o To evaluate the efficacy of intravenous azithromycin compared with meropenem in the treatment of extensively drug-resistant (XDR) enteric fever.\n2. Secondary Objectives:\n\n   * To evaluate the fever defervescence and Salmonella Typhi eradication\n   * To evaluate the cost-effectiveness of intravenous azithromycin versus meropenem in treating XDR enteric fever.\n3. Exploratory Objectives:\n\n   * To evaluate the drug resistance against intravenous azithromycin versus in treating XDR enteric fever.",[27],"Enteric Fever","RECRUITING","2026-05-05",{"date":31,"type":32},"2026-05-08","ACTUAL",{"date":34,"type":32},"2025-04-22",{"date":36,"type":21},"2027-01-15",{"name":38,"class":39},"Indus Hospital and Health Network","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":40},"100627540","effect-of-counselling-using-lifestyle-medicine-assessment-tool-on-hypertensive-patients-100627540","NCT07449962","Effect of Counselling Using Lifestyle Medicine Assessment Tool on Hypertensive Patients","Effect of Counselling of Patients With Hypertension Presenting in Family Medicine Clinics Using Lifestyle Medicine Assessment Tool.","Inclusion Criteria:\n\n1. Adult patients aged 18-65 yrs with diagnosed primary\u002Fessential hypertension, defined as two or more clinic BP readings of ≥130\u002F80 (ACC\u002FAHA Guidelines).\n2. If taking anti hypertensives, then on a stable regime i.e. no recent medication change for at least ≥4 weeks.\n3. Willing and able to participate in the study.\n\nExclusion Criteria:\n\n1. Diagnosed secondary hypertension.\n2. Moderate to severe CKD (eGFR \\\u003C60 ml\u002Fmin\u002F1.73m2).\n3. Moderate to severe ischemic heart disease.\n4. Diabetes Mellitus requiring insulin.\n5. Major psychiatric disorder such as dementia or schizophrenia.\n6. Pregnancy or Lactating mother.\n7. Unable to participate in study\u002F Severe mobility limitation.","18 Years","65 Years",{"count":51,"type":21},64,[53],"NA","The goal of this clinical trial is to learn if knowing and understanding a patient's daily habits and then giving clear advice on what changes to make can help control blood pressure better than the routine way of advising people with high blood pressure. The main questions it aims to answer are:\n\n* To learn if using the Lifestyle Medicine Assessment tool (A 21-item questionnaire) to understand the current lifestyle of people with hypertension and guide them accordingly, helps in lowering blood pressure more, as compared to routine advice?\n* To see if this way of guiding patients is more satisfactory for them then routine advice? Researchers will compare two groups of people with hypertension. One will be guided after assessing their current lifestyle with the Lifestyle Medicine Assessment Tool and one will be given routine guidance. The researchers will then see which group had better blood pressure control.\n\nParticipants will be:\n\n* Asked a few questions about their lifestyle and then they will be advised accordingly on ways to make it better.\n* They will also be asked to measure their blood pressure at home and bring the record with them when they come for their doctor's visit.",[56,57,58,59],"Lifestyle Intervention","Lifestyle Modification","Hypertension","Counselling",[61,62],"lifestyle counselling of hypertensive patients","Lifestyle Medicine Assessment Tool","NOT_YET_RECRUITING","2026-04-25",{"date":66,"type":32},"2026-04-30",{"date":68,"type":21},"2026-06",{"date":70,"type":21},"2027-02",{"name":38,"class":39},""]