[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Institut d'Investigacions Biomèdiques August Pi i Sunyer\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":75},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100629796","estimated-risk-of-preeclampsia-in-the-first-trimester-and-its-association-with-subclinical-atherosclerosis-and-cardiovascular-risk-in-women-with-type-1-diabetes-100629796",false,"NCT07479329","Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes","PREEATH-T1D","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Confirmed diagnosis of type 1 diabetes\n* At least one prior pregnancy with first-trimester preeclampsia screening (\\\u003C14 weeks gestation)\n* ≥3 years since last pregnancy\n\nExclusion Criteria:\n\n* Previous multiple pregnancy\n* Cardiovascular disease before pregnancy (coronary heart disease, stroke\u002FTIA, peripheral artery disease, heart failure)\n* Active pregnancy at time of evaluation\n* Alcohol or substance dependence (except nicotine\u002Fcaffeine) in the last 3 years\n* Active severe psychiatric disease, dementia, severe disability, or reduced life expectancy","FEMALE","18 Years",{"count":19,"type":20},1300,"ESTIMATED","OBSERVATIONAL","This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy.\n\nWomen with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.",[24,25,26],"Type 1 Diabetes","Preeclampsia","Preeclampsia (PE) Risk",[24,25,28,29,30,31,32],"Preeclampsia Risk","Preclinical carotid atherosclerosis","Carotid ultrasonography","Cardiovascular risk","Cardiovascular disease","NOT_YET_RECRUITING","2026-03-16",{"date":36,"type":37},"2026-03-18","ACTUAL",{"date":39,"type":20},"2026-04-10",{"date":41,"type":20},"2028-04-30",{"name":43,"class":44},"Institut d'Investigacions Biomèdiques August Pi i Sunyer","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},"100442213","fetal-brain-care-therapies-for-brain-neurodevelopment-in-fetal-growth-restriction-100442213","NCT05038462","Fetal Brain Care: Therapies for Brain Neurodevelopment in Fetal Growth Restriction","Inclusion Criteria:\n\n* Singleton pregnancies\n* Non-malformed fetus\n* Pregnancies with fetal growth restriction\n* 24-32.6 weeks of gestation\n\nExclusion Criteria:\n\n* Chromosomal or structural abnormalities diagnosed during pregnancy or in the neonatal period\n* Critical Doppler study suggesting the need for delivery within the next 14 days at the time of diagnosis: reverse end-diastolic velocity in the umbilical artery or ductus venosus pulsatility \\>95th centile\n* Maternal mental or psychiatric disorders\n* Maternal allergy to cow's milk protein",{"count":52,"type":20},304,"INTERVENTIONAL",[55],"NA","Singleton pregnancies being diagnosed of fetal growth restriction from 24 to 32.6 weeks of gestation will be randomized to two equally sized groups: maternal oral supplementation with Lactoferrin and DHA (Docosahexaenoic acid) or placebo.",[58,59],"Fetal Growth Retardation","Intrauterine Growth Restriction",[58,61,59,62,63,64],"Fetal Growth Restriction","Neurodevelopment","Lactoferrin","DHA","RECRUITING","2024-03-15",{"date":68,"type":37},"2024-03-18",{"date":70,"type":37},"2023-01-18",{"date":72,"type":20},"2026-12",{"name":43,"class":44},6,""]