[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Institut de Recherche en Sciences de la Sante, Burkina Faso\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":106},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100574454","validation-and-simplification-of-the-retinol-isotope-dilution-technique-in-burkinabe-schoolchildren-100574454",false,"NCT06759493","Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe Schoolchildren","RID_VAB","Inclusion Criteria:\n\n* School children aged 7-12 years\n\n  * Child's guardian or parent is willing to provide informed consent\n  * Child's family plans to remain resident in the study areas during the study period\n\nExclusion Criteria:\n\n* Clinical evidence of vitamin A deficiency a mis en forme : Anglais (Royaume-Uni)a mis en forme : Anglais (États-Unis)a mis en forme : Anglais (États-Unis)a mis en forme : Anglais (États-Unis)\n\n  * Severe malnutrition (weight-for age Z score (WAZ) or height-for-age Z score (HAZ) \\\u003C-3 SD)\n  * Serious illnesses including tuberculosis, symptomatic HIV infection\n  * Child aged \\\u003C6 years or \\>12 years",true,"ALL","7 Years","12 Years",{"count":21,"type":22},158,"ESTIMATED","OBSERVATIONAL","Two cross-sectional, repeated-pass, community-based studies will be carried out during the school year. The first study will be conducted from November to December. This period corresponds to the end of the rainy season and the end of the mango season, which is one of the main sources of vitamin A in the Orodara region.\n\nThe second survey will be carried out 5 to 6 months (April-May of the following year) after data collection for the first study, corresponding to the mango season. The same schoolchildren recruited during the first phase of data collection (5 to 6 months earlier) will be the participants in the second study. The interest of this study is to use nuclear techniques to implement a strategy for the precise and accurate determination of Vitamin A status in order to reinforce existing Vitamin A interventions and policies.",[26,27],"Vitamin A Deficiency","Inflammation",[29,30,31,32,33],"Vitamin A","School","children","Isotope","Burkina Faso","RECRUITING","2025-03-16",{"date":37,"type":38},"2025-03-18","ACTUAL",{"date":40,"type":38},"2024-11-21",{"date":42,"type":22},"2025-06-30",{"name":44,"class":45},"Institut de Recherche en Sciences de la Sante, Burkina Faso","OTHER_GOV",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":46},"100576982","effectiveness-of-an-alternative-protocol-in-the-management-of-acute-malnutrition-100576982","NCT06792370","Effectiveness of an Alternative Protocol in the Management of Acute Malnutrition","Effectiveness of an Alternative Protocol in the Management of Acute Malnutrition in Children Aged 6-59 Months in Burkina Faso: Reduced Dose of RUTF for SAM Children and RUTF Instead of RUSF for MAM Children","Alternat-MAL","1. MAM\n\n   Inclusion Criteria:\n   * Anthropometric measures:\n\n     * (115 mm ≤ MUAC\\\u003C 125 mm and -3 SDs ≤ WLZ \\\u003C -2 SDs) OR\n     * (115 mm ≤ MUAC\\\u003C 125 mm and WLZ ≥ -2 SDs) OR\n     * (MUAC ≥ 125 mm and -3 SDs ≤ WLZ \\\u003C -2 SDs).\n   * Age: 6 to 59 months\n   * Parents' acceptance of biweekly visits until programme discharge and monthly visits for the post-programme follow up\n\n   Exclusion Criteria:\n   * Failure of appetite test\n   * Medical complications requiring hospital treatment\n   * Presence of any congenital anomaly or underlying chronic disease that may affect growth or the risk of infection\n   * Presence of bilateral oedema\n   * History of allergies to peanuts, milk, or soya\n   * Relapse from MAM treatment or transfer from SAM treatment\n   * Children who have recently (\\\u003C2 months) taken part in a nutrition programme;\n   * Residence outside the study area\n   * Mother or caregivers deemed unable to comply with the necessary requirements of the study (particular medical condition of the mother or caregivers, etc.)\n2. SAM\n\nInclusion Criteria:\n\n* Anthropometric measures MUAC\\\u003C 115 mm or WLZ\\\u003C - 3 SDs;\n* Age: 6-59 months;\n* Parents' acceptance of weekly visits until programme discharge and monthly visits for the post-programme follow up.\n\nExclusion Criteria:\n\n* Failure of appetite test\n* Medical complications requiring hospital treatment\n* Presence of any congenital anomaly or underlying chronic disease that may affect growth or the risk of infection\n* Presence of bilateral oedema\n* History of allergies to peanuts, milk or soya\n* Relapse from MAM treatment or transfer from SAM treatment\n* Children who have recently (\\\u003C2 months) taken part in a nutrition programme;\n* Residence outside the study area;\n* Mother or caregivers deemed unable to comply with the necessary requirements of the study (particular medical condition of the mother or caregivers, etc.)","6 Months","59 Months",{"count":58,"type":22},3521,"INTERVENTIONAL",[61],"NA","This experimental study aims to test an alternative protocol for managing acute malnutrition in children aged 6-59 months in Burkina Faso. This alternative protocol consists of using RUTF instead of RUSF for the management of moderate acute malnutrition and reduced-dose RUTF instead of standard-dose RUTF for the treatment of severe acute malnutrition.\n\nThe main questions are:\n\n1. Does treating children with moderate acute malnutrition using RUTF lead to a non-inferior programmatic and sustained recovery rate compared to the standard care with RUSF?\n2. Does treating children with uncomplicated severe acute malnutrition using a reduced dose of RUTF lead to a non-inferior programmatic and sustained recovery rate compared to the standard care with a standard dose of RUFT?\n\nSecondly, the study will investigate the effect of this alternative protocol compared to the standard protocol on cost-effectiveness, psychomotor development, weight and linear growth and incidence of relapses.",[64],"Acute Malnutrition with No Complications",[66,67,68,69,70,71,72,73,74],"Effectiveness","acute malnutrition","management","treatment","reduced dose","Ready-to-Use Supplementary Foods","Ready-to-Use Therapeutic Foods","uncomplicated","without complication","NOT_YET_RECRUITING","2025-01-20",{"date":78,"type":38},"2025-01-24",{"date":80,"type":22},"2025-05",{"date":82,"type":22},"2026-12",{"name":44,"class":45},{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":59,"phases":95,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":105,"locationsCount":46},"100484292","microbiome-directed-food-for-sustained-recovery-from-acute-malnutrition-100484292","NCT05586139","Microbiome-Directed Food for Sustained Recovery From Acute Malnutrition","Efficacy of a Food Targeting the Microbiota for a Sustained Recovery of Children With Uncomplicated Acute Malnutrition","MDF","Inclusion Criteria:\n\n* Age between 6 and 23 months\n* Moderate wasting: WHZ \\\u003C -2 and ≥ -3 or MUAC \\\u003C 125 mm and ≥ 115mm or - Severe wasting: WHZ \\\u003C -3 or MUAC \\\u003C 115 mm\n\nExclusion Criteria:\n\n* Bilateral pitting edema\n* Not eating\u002Flack of appetite\n* Current illness medical complications requiring inpatient treatment\n* Presence of any congenital abnormality or underlying chronic disease that may affect growth or risk of infection\n* Known contraindication\u002Fhypersensitivity\u002Fallergy to MDCF of RUSF ingredients (chickpea flour, soy flour, banana, peanut)\n* Relapse from MAM treatment or transfer from SAM treatment\n* Children recently (\\\u003C2 months) or enrolled in a nutrition program\n* Residence outside the study area","23 Months",{"count":94,"type":22},6200,[61],"The goal of this experimental study is to test the efficacy of a new formulation - The microbiome-directed food (MDF) to treat acute malnutrition among children aged 6 to 23 months. The main questions are:\n\n* Does treating children with moderate or severe uncomplicated malnutrition using MDF leads to higher programmatic recovery rate compared to standard of care ?\n* Does treating children with moderate or severe uncomplicated malnutrition using MDF leads to higher sustained recovery rate compared to standard of care ? The MDF will be compared to Ready-to-use supplementary food (RUSF) for moderately malnourished children, and to Ready-to-use therapeutic food (RUTF) for severely malnourished children to see the effects on recovery and sustained recovery rate.",[98],"Acute Malnutrition With no Complications","2024-03-12",{"date":101,"type":38},"2024-03-13",{"date":103,"type":22},"2024-10",{"date":82,"type":22},{"name":44,"class":45},""]