[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Instituto Bernabeu\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":94},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":24,"studyType":25,"phases":4,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100620969","non-invasive-preimplantation-genetic-screening-for-aneuploidies-and-clinical-outcomes-in-egg-donation-patients-100620969",false,"NCT07364526","Non-Invasive Preimplantation Genetic Screening for Aneuploidies and Clinical Outcomes in Egg Donation Patients","Non-invasive Preimplantation Genetic Screening (niPGTA) in Oocyte Donation Patients.","niPGTAdon","Inclusion Criteria:\n\n* Women between 18 and 50 years old who are oocyte recipients.\n* Signed consent form\n* Transfer of a single blastocyst-stage embryo\n* Male with normal sperm FISH\n\nExclusion Criteria:\n\n* Uterine malformations\n* Abnormal karyotypes in either partner\n* Failure to sign informed consent",true,"FEMALE","18 Years","50 Years",{"count":22,"type":23},164,"ESTIMATED","3 Years","OBSERVATIONAL","Preimplantation genetic testing for aneuploidies (PGT-A) is commonly used in IVF but requires embryo biopsy and shows limited benefit in egg donation cycles. Non-invasive PGT-A (niPGTA), based on the analysis of cell-free embryonic DNA in spent culture media, offers a promising biopsy-free alternative. This prospective, blinded study in egg donation cycles will evaluate whether niPGTA-detected aneuploidy is associated with implantation failure and pregnancy loss, assessing its potential clinical value as a non-invasive embryo selection tool.",[28],"IVF",[30],"niPGTA","RECRUITING","2026-01-21",{"date":34,"type":35},"2026-01-23","ACTUAL",{"date":37,"type":23},"2026-02-26",{"date":39,"type":23},"2027-12-01",{"name":41,"class":42},"Instituto Bernabeu","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":43},"100531082","phase-4-trap-study-testosterone-for-androgen-receptor-polymorphism-100531082","NCT06195163","TRAP Study: Testosterone for Androgen Receptor Polymorphism","Transdermal Testosterone Pretreatment in Poor Responders With Androgen Receptor Polymorphism Undergoing ICSI: A Randomized Clinical Investigation.","TRAP","Inclusion Criteria:\n\n* Patients with low ovarian reserve according to Bologna criteria: at least two of the following three:\n\n  1. Age equal to or greater than 40 years.\n  2. Previous cycle with less than 4 oocytes retrieved.\n  3. Low ovarian reserve markers (antral follicle count \\\u003C5-7; AMH \\\u003C0.5-1.1 ng).\n* Carriers of androgen receptor polymorphism: between 22 and 24 CAG repeats.\n* Body Mass Index (BMI) less than 32.\n* Indication for in vitro fertilization.\n* Presence of both ovaries.\n* Absence of ovarian cysts.\n* Absence of endometriosis.\n* Normal karyotype and fragile X study.\n* Absence of severe male factor.\n* Semen sample from ejaculate.\n* Ability to comply with the study protocol.\n* To have given written consent.\n\nExclusion Criteria:\n\n* Non-compliance with instructions or non-formalization of informed consent.\n* Concurrent participation in another study.","40 Years",{"count":54,"type":23},100,"INTERVENTIONAL",[57],"PHASE4","To determine whether pretreatment with transdermal testosterone increases the number of cumulus-oocyte complexes (COCs) obtained after ovarian stimulation by more than 1.5 in patients with low ovarian reserve and androgen receptor polymorphism undergoing intracytoplasmic sperm injection (ICSI).",[60],"Fertility Disorders",[62],"ovarian stimulation; testosterone","NOT_YET_RECRUITING","2025-05-06",{"date":66,"type":35},"2025-05-09",{"date":68,"type":23},"2025-09-30",{"date":70,"type":23},"2026-12-31",{"name":41,"class":42},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":80,"targetDuration":82,"studyType":25,"phases":4,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":43},"100513046","impact-of-endometrial-compaction-on-reproductive-outcomes-after-cryotransfer-of-euploid-embryos-in-a-natural-cycle-100513046","NCT05960370","Impact of Endometrial Compaction on Reproductive Outcomes After Cryotransfer of Euploid Embryos in a Natural Cycle","Impact of Endometrial Compaction on Reproductive Outcomes After Cryotransfer of Euploid Embryos in a Natural Cycle: Prospective Cohort Study","Compaction","Inclusion Criteria:\n\n* Aged 18 to 50 years\n* Primary or secondary infertility\n* Normal uterine cavity\n* Endometrial preparation in a modified natural cycle for single embryo transfer\n* Embryo in blastocyst state from own oocyte or oocyte donation cycles, who had normal results on preimplantation genetic testing for aneuploidy (PGT-A) via trophectoderm biopsy.\n\nExclusion Criteria:\n\n* Uterine or endometrial disease (multiple myomatosis \\[\\>3 fibroids of \\> 3 cm\\], adenomyosis, Asherman syndrome)\n* Difficulties in correctly measuring endometrial thickness due to a retroverted or tilted uterus\n* History of recurrent implantation failure (3 or more transferred blastocysts of good quality, from their own oocyte \\[\\\u003C35 years\\] or oocyte donation); recurrent early Pregnancy Loss (the loss of two or more pregnancies before 10 weeks of gestational age.\n* Suboptimal endometrial response (endometrium \\\u003C 6 mm on the day of ovulation triggering).",{"count":81,"type":23},206,"4 Months","Multicenter prospective observational cohort study, comparing ongoing pregnancy rates in natural cycles for euploid embryo transfer in patients who present endometrial compaction at the time of the transfer versus those who have a stable or greater endometrial thickness with respect to the estrogenic phase.",[85],"Infertility Due to Nonimplantation","2024-10-02",{"date":88,"type":35},"2024-10-03",{"date":90,"type":35},"2022-06-15",{"date":92,"type":23},"2025-06-15",{"name":41,"class":42},""]