[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Instituto Ramón y Cajal de Investigación Sanitaria\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100613346","success-score-validation-in-fuchs-dystrophy-100613346",false,"NCT07265388","SUCCESS Score Validation in Fuchs Dystrophy","Validation and Extension of the SUCCESS Score for Fuchs Dystrophy After Cataract Surgery","SUCCESS","Inclusion Criteria:\n\n* Adults aged ≥40 years.\n* Clinical diagnosis of Fuchs endothelial corneal dystrophy (FECD) grade ≥2 on the modified Krachmer scale.\n* Presence of visually significant cataract requiring phacoemulsification surgery.\n* Ability to provide informed consent and comply with study procedures.\n* Availability of preoperative Scheimpflug tomography and corneal densitometry measurements.\n\nExclusion Criteria:\n\n* Epithelial or stromal edema precluding reliable corneal imaging.\n* Previous ocular surgery (including corneal or intraocular procedures).\n* Corneal trauma, infection, or inflammation affecting endothelial integrity.\n* Coexisting ocular pathologies that could confound postoperative assessment (e.g., advanced glaucoma, macular degeneration).","ALL","40 Years",{"count":20,"type":21},250,"ESTIMATED","5 Years","OBSERVATIONAL","This prospective multicenter diagnostic study aims to externally validate and extend the SUCCESS Score for predicting the need for endothelial keratoplasty after cataract surgery in patients with Fuchs endothelial corneal dystrophy (FECD). The model's performance and clinical utility are assessed using discrimination, calibration, and reclassification metrics.",[26],"Fuchs Endothelial Corneal Dystrophy",[26,28,29,30,31,32],"Cataract Surgery","endothelial keratoplasty","Diagnostic Accuracy","Prognostic Validation","Predictive Modeling","RECRUITING","2025-11-24",{"date":36,"type":37},"2025-12-04","ACTUAL",{"date":39,"type":37},"2020-06-01",{"date":41,"type":21},"2026-12",{"name":43,"class":44},"Instituto Ramón y Cajal de Investigación Sanitaria","OTHER",""]