[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"International Food Policy Research Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":137},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,50,81,93,112],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100053887","expanding-coverage-of-severe-acute-malnutrition-sam-treatment-in-kenya-100053887",false,"NCT06441305","Expanding Coverage of Severe Acute Malnutrition (SAM) Treatment in Kenya","Assessing the Impact, Implementation and Cost of Empowering Community Health Promoters to Improve Wasting Treatment Coverage in Turkana County Through Family-led MUAC Scale-up, Weight-for-age Screening, and Defaulters' Follow-up","R-SWITCH","Inclusion Criteria:\n\n* Household in a village of the study area covered by a CHP (although the child may or may not be registered by a CHP) AND\n* Child is 6-59.9 months of age AND\n* Caregiver consents to be part of the study AND\n* any of the following:\n\n  * WHZ \\\u003C -3 (relative to WHO 2006 reference) OR\n  * MUAC \\\u003C115 mm OR\n  * Presence of bilateral edema OR\n  * receiving treatment as follow-up for an initial SAM condition on the way to full recovery\n\nexclusion criteria is:\n\n* Congenital malformation that makes anthropometric measurements impossible.\n* Length is below 54 cm or height is above 120cm.",true,"ALL","6 Months","5 Years",{"count":22,"type":23},1600,"ESTIMATED","INTERVENTIONAL",[26],"NA","Child wasting is a type of malnutrition which occurs when a child becomes too thin. This medical condition increases the risk of becoming sick or dying. A child with severe wasting needs to be seen in a medical consultation to check on health status and to receive some medicine and a medical food supplement for daily consumption until cured. Yet, only a small proportion of children suffering from severe wasting are presently receiving appropriate treatment.\n\nIn Kenya, there is an opportunity to build on the existing network of community health promoters (CHPs) to increase the number of children with wasting who are identified and treated. In intervention areas, CHPs will be equipped with smartphones and an application which provides guidance on household members to visit and simple actions to take, related to health. CHPs will distribute color-coded mid-upper arm circumference tapes to households with young children and train caregivers on how to use it. After training, CHPs will send Short Message Services (SMS) to remind caregivers to regularly measure the arm circumference of the child. In addition, CHPs will receive a scale to measure the weight of children every month. Finally, wasted children registered in the treatment program who fail to attend a planned consultation will be flagged to their CHP through the phone application, and CHPs will conduct a specific home visit to investigate and help solve potential issues.\n\nThe study will assess whether this community intervention (called SWITCH) allows to identify and treat more children suffering from severe wasting. Before the start of the intervention, the proportion of wasted children receiving treatment in 40 community units in Turkana South, Turkana East and Aroo will be assessed. After this survey, a computer will randomly select 20 community units where the intervention will be scaled up. The survey will be repeated after 2 years to assess if the proportion of severely wasted children receiving treatment is higher in the area where the intervention was scaled up compared to the area where it was not scaled up.\n\nIn addition, after 1 year of implementation, the study will assess how the intervention was scaled up, what are the main challenges, and what are the overall perceptions on the intervention in the community among those who receive it and those who deliver it. Finally, costs of the various components of the intervention will be measured for all actors involved, including for caregivers.",[29,30,31],"Acute Malnutrition, Severe","Malnutrition, Child","Wasting",[33,34,35,31,36],"Outpatient Therapeutic Feeding Program","Treatment","Screening","Severe acute malnutrition","RECRUITING","2026-07-09",{"date":40,"type":41},"2026-07-13","ACTUAL",{"date":43,"type":41},"2024-06-03",{"date":45,"type":23},"2027-07-30",{"name":47,"class":48},"International Food Policy Research Institute","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":18,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":24,"phases":61,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":49},"100643436","randomized-evaluation-of-voucher-interventions-for-value-and-effectiveness-revive-in-philippines-100643436","NCT07640594","Randomized Evaluation of Voucher Interventions for Value and Effectiveness (REVIVE) in Philippines","REVIVE","Inclusion Criteria:\n\n* Households enrolled in the REVIVE study sample drawn from Listahanan 3-eligible low-income households\n* Residency within selected study clusters in the study municipalities\n* Household consent to participate in the study and all survey components\n* Availability of a primary respondent (meal planner or primary food preparer) willing to participate in household interviews\n* For individual dietary assessment components: presence of at least one woman of reproductive age (15-49 years) and\u002For at least one child under five years of age, where applicable\n\nExclusion Criteria:\n\n* Households unwilling or unable to provide informed consent\n* Households not residing within the designated study clusters at the time of baseline data collection\n* Inability to complete core survey modules due to communication barriers or other conditions preventing reliable data collection","0 Months","99 Years",{"count":60,"type":23},5320,[26],"This study aims to evaluate whether revised food voucher programs, combined with nutrition education sessions, can improve food security, dietary quality, nutrition knowledge, and nutritional outcomes among low-income households in the Philippines. Researchers will compare different monthly voucher amounts-Philippine Peso (PhP) 3,000, PhP 5,000, and PhP 8,000-with a no-voucher control group to determine which approach is most effective.\n\nThe main questions the study aims to answer are:\n\n* Do food vouchers improve household food security, reduce hunger, and improve dietary quality and nutrient intake?\n* Do larger voucher amounts lead to greater improvements in nutrition and health outcomes?\n* Does enhanced nutrition education improve nutrition knowledge and healthy eating practices?\n\nParticipants will:\n\n* Receive either a monthly food voucher or no voucher, depending on study group assignment\n* Attend nutrition education and Social and Behavior Change Communication (SBCC) sessions if assigned to a voucher group\n* Complete household interviews on food consumption, household expenditures, food security, and nutrition knowledge\n* Participate in dietary assessments and anthropometric measurements for women and children under 5 years of age",[64,65,66,67],"Food Insecurity","Undernutrition","Diet Quality","Nutrition Knowledge",[69,70,71,72],"Food Vouchers","Social and Behavior Change Communication","Cluster-Randomized Controlled Trial","Philippines","2026-06-06",{"date":75,"type":41},"2026-06-10",{"date":77,"type":41},"2026-04-29",{"date":79,"type":23},"2027-03-30",{"name":47,"class":48},{"id":82,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":83,"targetDuration":4,"studyType":24,"phases":84,"briefSummary":27,"conditions":85,"keywords":86,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":92,"locationsCount":49},"100549995",{"count":22,"type":23},[26],[29,30,31],[33,34,35,31,36],"2026-03-25",{"date":89,"type":41},"2026-03-27",{"date":43,"type":41},{"date":45,"type":23},{"name":47,"class":48},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":15,"eligibilityCriteria":99,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":100,"targetDuration":4,"studyType":24,"phases":102,"briefSummary":103,"conditions":104,"keywords":105,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":106,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":49},"100545330","increasing-the-coverage-of-severe-acute-malnutrition-sam-treatment-in-ethiopia-100545330","NCT06380504","Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia","Effect of Leveraging Community-level Structures to Strengthen Prevention, Screening and Treatment of Severe Acute Malnutrition in Ethiopia","Inclusion Criteria:\n\n* Child 6-59 months of age\n* Suffering from SAM (defined as MUAC \\\u003C 115mm or presence of bilateral pitting edema or Weight-for-Length Z-score \\\u003C-3) OR currently enrolled in SAM OTP\n\nExclusion Criteria:\n\n\\- Anthropometric malformation or being handicapped which hampers anthropometric measurements.",{"count":101,"type":23},1080,[26],"The R-SWITCH intervention aims to address the low coverage of treatment for severe wasting (SAM) by leveraging existing community groups to deliver an integrated package focused on prevention, screening, referral, and treatment of SAM. It includes behavior change communication on child nutrition and health, active screening, improved passive screening at health posts, and follow-up of referred cases and those enrolled in outpatient treatment programs (OTP). The primary objectives of the R-SWITCH studies are to assess the intervention's impact on OTP coverage, identify implementation barriers and facilitators, and evaluate its cost-efficiency and cost-effectiveness.",[29,30,31],[33,34,35,31,36],{"date":89,"type":41},{"date":108,"type":41},"2024-05-02",{"date":110,"type":23},"2027-06-30",{"name":47,"class":48},{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":24,"phases":123,"briefSummary":124,"conditions":125,"keywords":4,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":49},"100625240","reduced-dosage-andor-visitation-protocol-for-the-treatment-of-acute-malnutrition-in-kenya-100625240","NCT07420062","Reduced Dosage and\u002For Visitation Protocol for the Treatment of Acute Malnutrition in Kenya","Research to Improve the Screening for Wasting and the Identification and Treatment of Wasted Children (R-SWITCH): Reduced Dosage and\u002For Visitation Protocol for the Treatment of Severe Acute Malnutrition in Kenya","RSWITCH","Inclusion Criteria:\n\n* 6-59.9 months of age at admission into treatment\n* Child admitted to the national treatment program according to the following criteria:\n\n  * For SAM: WHZ \\\u003C-3 or MUAC \\\u003C115 mm or presence of bilateral oedema, absence of clinical complications, pass the appetite test\n  * For high-risk MAM: -3 ≥ WHZ \\\u003C-2 or 115mm ≥ MUAC \\\u003C125 mm, and one or more of the following factors: MUAC of 115-119 mm, weight-for-age z-score (WAZ) \\\u003C -3, age \\\u003C 24 months, failing to recover from MAM after receiving other interventions (e.g. counselling, nutrient dense diet), relapse, history of SAM, co-morbidity (medical problems needing mid- or long-term follow-up care, and with a significant association with nutritional status, such as HIV, tuberculosis, or a physical or mental disability)\n* Accompanied by caregiver or legal guardian\n* Caregiver or legal guardian consents to participate\n\nExclusion Criteria:\n\n* SAM requiring hospitalization (presence of clinical complications, failure to pass the appetite test, or presence of bilateral pitting edema)\n* Enrolled in MAM or SAM treatment program before implementation of the treatment protocols to which the facilities were randomized\n* Presence of physical abnormalities that make measurement of anthropometry impossible\n* Caregiver has intention to move out of the study area within the next 3 months","59 Months",{"count":122,"type":23},2274,[26],"Severe acute malnutrition (SAM) places children at significant risk of mortality. Outpatient treatment programs are effective but there is a need to increase treatment coverage and reduce costs of treatment. Reducing the dosage of therapeutic food products and\u002For reducing visitation required by caregivers may be beneficial but evidence is limited on the treatment outcomes and costs of these approaches.\n\nThis study will compare two dosage options (full vs reduced dosages) of the World Health Organization protocol for the treatment of SAM and high-risk moderate acute malnutrition (HR-MAM) to each other and to the Kenya national protocol (which involves reducing dosage, changing treatment product, and reducing visitation schedule during the course of the treatment once the SAM child reaches the criteria for moderate acute malnutrition before recovery), in terms of treatment performance and cost. We will conduct a cluster-randomized controlled trial including 45 facilities in Samburu, West Pokot, and Wajir sub-counties. Children 6-59 months old being admitted into outpatient treatment programs for SAM or HR-MAM will be enrolled. Outcomes will be recovery, default, death, transfer, and non-response rates; treatment adherence; mean amount of therapeutic products needed for recovery; mean length of stay; and anthropometry at discharge. We will conduct a costing study in which we will estimate the costs per child admitted into treatment and cost per treated child recovered. We will estimate the non-inferiority of each of the two WHO protocol dosage options (full vs reduced) compared to the Kenya national protocol, and of the two WHO protocol options compared to each other (full vs reduced). Enrollment will begin in early 2026, and continue for 10 months. We will also conduct an observational sub-study documenting outcomes on children with MAM but who are not considered high risk in a sub-set of study facilities.\n\nEvidence generated from the study will identify the optimal treatment strategy for better treatment performance and lower cost, providing policymakers in Kenya and across the globe with high-quality evidence to inform policy change.",[126,29,127,31],"Acute Malnutrition in Childhood","Acute Malnutrition, Moderate","NOT_YET_RECRUITING","2026-02-12",{"date":131,"type":41},"2026-02-19",{"date":133,"type":23},"2026-03-01",{"date":135,"type":23},"2027-05",{"name":47,"class":48},""]