[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"International Piezosurgery Academy\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":60},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100582678","effect-of-cavitation-in-post-extractive-socket-healing-100582678",false,"NCT06866431","Effect Of Cavitation In Post-Extractive Socket Healing","Piezoclean","Inclusion Criteria:\n\n* Age between 18 and 100 years\n* Two single rooted hopeless teeth of the same arch to be extracted\n* ASA scale value equal or less than 3\n* Signed informed consent\n\nExclusion Criteria:\n\n* General contraindications for dental and\u002For surgical treatments\n* Inflammatory and autoimmune disease of the oral cavity\n* Uncontrolled diabetes (HbA1c \\> 7.5%)\n* History of malignancy requiring chemotherapy or radiotherapy within the past five years\n* Previous immunosuppressant bisphosphonate or high dose corticosteroid therapy\n* Heavy smokers (\\> 20 cigarettes \u002Fday)\n* Pregnancy or lactating women\n* No compliance\n* Extraction performed after raising a flap and\u002For with osteotomy","ALL","18 Years","100 Years",{"count":20,"type":21},84,"ESTIMATED","OBSERVATIONAL","In everyday clinical practice, the proper management of the post-extraction socket is crucial in order to enable an optimal healing of the wound and a close post-surgical monitoring is critical to prevent possible complications. After an injury, the cellular reaction starts early, presenting significant changes as soon as 12 to 24 hours later. Favourable wound healing begins with the timely formation, organization, stabilization, and attachment of the blood clot. The stability of the clot is influenced by various factors including the host response, local anatomical characteristics, presence of bacteria and severity of surgical trauma. Delayed healing can lead to increased complications, patient discomfort, and potential procedure failures. In the light of these considerations, the proven effectiveness of piezoelectric devices to facilitate healing mechanisms is known in literature. Inverse piezoelectric effect, as used in current devices, creates mechanical shock waves that oscillate linearly at sonic and ultrasonic frequencies (from 30 to 30.000 Hz). In addition, mechanical micro-movements with a frequency between approximately 24 and 30 kHz create a cavitation effect in the irrigation solution, limiting intraoperative bleeding, thereby increasing the visibility and safety of the procedure.\n\nThe purpose of the present study is to evaluate if the application of cavitation effect of post-extractive socket is capable of reducing healing time and Numeric Pain Rating Scale (NPRS) values.",[25,26],"Cavitation","Healing of Extraction Socket","RECRUITING","2025-05-27",{"date":30,"type":31},"2025-05-28","ACTUAL",{"date":33,"type":31},"2025-04-01",{"date":35,"type":21},"2026-03-31",{"name":37,"class":38},"International Piezosurgery Academy","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":49,"conditions":50,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":39},"100578240","clinical-influence-of-different-surface-treatments-on-implant-stabiity-100578240","NCT06808724","Clinical Influence of Different Surface Treatments on Implant Stabiity","Clinical Influence of Different Surface Treatments on Implant Stabiity: a Prospective Observational Clinical Study","Inclusion Criteria:\n\n* Age older than 18 years old;\n* Indication for an implant-supported rehabilitation in the left and right upper premolar\u002Ffirst molar areas;\n* The area in which the implants will be placed must have had at least 6 months of healing;\n* No use of grafts or bone substitutes following tooth extraction;\n* Bone volume measuring at least 10 mm in height and 6 mm in width;\n* Absence or decision to not wear a removable prosthesis during the healing period;\n* Patients with good and stable oral hygiene;\n* Signed informed consent form.\n\nExclusion Criteria:\n\n* Acute myocardial infarction within the previous six months;\n* Uncontrolled bleeding disorders;\n* Uncontrolled diabetes (HBA1c \\> 7.5%);\n* Radiotherapy in the head-neck area in the previous 48 months;\n* Immunocompromised patients (es. AIDS \u002F chemotherapy);\n* Current or previous treatment with antiresorptive drugs via intravenous injection;\n* Psychological or psychiatric disease;\n* Alcohol and \u002For drugs abuse;\n* Heavy smokers (more than 10 cigarettes \u002F day);\n* Plaque index \\>20% and\u002For bleeding on probing \\>10%\n* Pregnant or breastfeeding patients;\n* Patients refusing to participate in follow-up checks.",{"count":48,"type":21},32,"The goal of this observational study is to monitor, within a cohort of patients requiring rehabilitation at two different sites in the premolar area, the primary and secondary stability of implants placed with different surface treatments: vacuum-plasma activation, ozonated oil and non-activated implants.",[51],"Edentulous Alveolar Ridge","2025-02-04",{"date":54,"type":31},"2025-02-05",{"date":56,"type":31},"2025-01-31",{"date":58,"type":21},"2030-12-31",{"name":37,"class":38},""]